Among rheumatic diseases reactive arthritis occupies one of the leading places in terms of prevalence and it is one of the most common chronic inflammatory joint diseases. When the process is chronic, destructive processes in the joints develop up to ankylosing. This article presents the results of studies on the features of the clinical course of reactive arthritis of post-enterocolitic and urogenital forms. The study was carried out in 120 patients with an established diagnosis of reactive arthritis.
In many countries and in our country reactive arthritis (RA) is a topical rheumatologic problem requiring early and individual therapy. Recently in the diagnostics of RA there is an active search of early biomarkers (BM) of articulate structures damage, which provide revealing of the symptoms of lesion of articulate soft tissues elements at the early stages of the disease. It can also help to assess the stage of lesion and prognosis of the disease. Later it will assist to prescribe adequate therapy according to the stage of the pathological process and perform monitoring of the therapy [1].
Reactive arthritis is an inflammatory lesion of the joints that occurs as a reaction to the invasion of the body by any infectious agents. The high social significance of nosologies dictates the need to search for reliable cartilage biomarkers that have diagnostic value not only in recognizing degenerative changes at an early stage of joint deseases, but also in monitoring the effectiveness of treatment.