The article gives a brief description of viral diarrhea, rota- and coronavirus infection, colibacillosis and proteosis of calves. data on the effect of the blood of cows vaccinated with the activated, associated vaccine "Enterovak-5" against viral diarrhea, rota, coronavirus infection, colibacteriosis and proteosis on the hematological indicators of calves. It was found that this vaccine does not have a negative effect on the hematological parameters of the blood of vaccinated cows.
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