496
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE
“
MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS
”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
EFFECTIVENESS AND SAFETY OF PHYTOTHERAPY OF THE MEDICINAL
PLANT - PAPAVER SOMNIFERUM L .)
Akhmadjonov K.K.
Azamatov A.A.
Ergasheva M.J.
State Institution "The center for pharmaceutical products safety" under the Ministry of Health
of the Republic of Uzbekistan, Tashkent city, Republic of Uzbekistan
e-mail: dr.k17111998@gmail.com
https://doi.org/10.5281/zenodo.17343194
Relevance.
Opium poppy, an annual herbaceous plant, is widely cultivated in southern Central
Asia. Its petals contain 0.05% alkaloids and fatty acids. The greatest interest in studying this plant
lies in its effects on the nervous system, exhibiting a sedative effect, as well as less pronounced
hypnotic and analgesic properties. It is widely known for its hemostatic effect. An infusion made
from the petals of the opium poppy is highly valued for its cough suppressant effect. Given its well-
known beneficial pharmacological effects, the potential for adverse effects of the opium poppy cannot
be ruled out.
Purpose of the study.
The purpose of this study is
to determine the effectiveness of opium
poppy therapy and at the same time to define precautions for herbal medicine.
Materials and methods.
The main resources we used in our study were a textbook on clinical
pharmacology, articles devoted to the anatomical and morphological structure of the opium poppy
plant, and a chemical-toxicological analysis of the constituents of opium poppy.
Results.
In this study, we examined the characteristic properties of opium poppy, as well as its
pharmacological effects on human organ systems. Its widespread use in folk medicine is based on its
diverse chemical composition. Its effectiveness against coughs is due to the codeine it contains, which
facilitates expectoration. It is recommended to use a mixture containing opium poppy petals. This
mixture also has an expectorant effect. Due to its nervous system depressant properties, opium poppy
is considered a powerful pain reliever. Its effectiveness can also be demonstrated in the treatment of
insomnia. The danger of opium poppy, as a poisonous plant, is manifested in overdosing on
medications made from it. For safety reasons, it is recommended to avoid using opium poppy-based
medications in cases of general exhaustion for pain relief and respiratory failure. The use of opium
poppy carries a significant risk of cardiac arrhythmia. General contraindications to the use of opium
poppy-based medications include liver damage, children under two years of age, and the elderly.
Opium poppy and alcohol are considered ineffective combinations, so alcoholism is a
contraindication. The effects of concomitant use of certain medications with opium poppy-based
medications should also be considered. For example, lopinavir prolongs the elimination of opium
poppy-based medications, while tocilizumab, conversely, reduces the elimination of opium poppy
alkaloids.
Conclusions.
1. Based on our research, we can conclude that the effectiveness of medications
made from the opium poppy plant is greatest only when administered in the correct dosage.
2. To ensure safe use of opium poppy, it is necessary to take into account the general condition
of the patient, age, gender, bad habits, condition of the liver, respiratory and cardiovascular systems.
