264
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE
“
MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS
”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
ANALYSIS OF THE TRACE ELEMENT COMPOSITION OF TOOTHPASTES
Radin M.A.
Radin M.M.
1
Barmashov S.N.,
St. Petersburg State University of Chemistry and Pharmacy, Department of Physical and
Inorganic Chemistry, Russia
St. Petersburg Pavlov State Medical University, Department of Propaedeutics of Dental
Diseases, Russia
e-mail: radin.michail@pharminnotech.com
https://doi.org/10.5281/zenodo.17334077
The aim of the study is to determine the micro- and macronutrient composition of toothpastes
from various price categories using atomic emission spectral analysis to assess their safety and
effectiveness.
Atomic emission spectral analysis is a method based on the study of the optical emission spectra
of atoms that occur during the transition of electrons from excited energy levels to the main ones.
During the analysis, the sample is atomized in a high-temperature plasma (4000 °C), after which the
characteristic spectral lines of the elements are recorded. The method allows for qualitative and
quantitative analysis of the elemental composition with high sensitivity and selectivity.
Materials and methods. The study was carried out on a DFS-452 spectrograph with a
photodiode recording system. Paste samples were applied to carbon electrodes, excited in an arc
discharge (18 A, 380 V), and then analyzed in the range of 190-1100 nm. The spectra were processed
using the Atom software and a database of spectral lines.
Results
1. Toothpaste of high price category (Fig. 1)
- Macronutrients: Na, P, Si, Zn, Cr, Fe, Mn.
- Trace elements: Cu, Ni, Ti, Al, V.
- The absence of toxic elements (Pb, As,
Hg)
confirms compliance with standards.
2. Low price toothpaste:
- Macronutrients: Al, Ca, Na, Si, Zn.
- Trace elements: Cu, Fe, Mn, Ni, P, Ti, V.
The increased content of Al (in the form of
aluminum oxide) requires an additional assessment of the risks of accumulation in the div.
Useful elements were found in the studied samples: Ca, P, Zn, they contribute to the
remineralization of enamel and have antibacterial properties, Si (SiO2) is a safe, alternative abrasive.
Elements contributing to potential risks: Al (Al2O3) is an alternative, more harmful abrasive, can
bind phosphates, disrupting mineral metabolism, Cr and Mn are toxic in high concentrations.
The method confirmed the absence of toxic elements in the studied pastes, but revealed
differences in the content of functional components. Expensive pasta shows a more balanced
composition with a predominance of remineralizing and antimicrobial elements. The data obtained
can be used to optimize toothpastes formulations, taking into account regional peculiarities (for
example, mineral deficiency in the soft water of the Northwest).
