In this article, opinions were expressed on the improvement of early-stage diagnostic factors and the optimal pathways of therapeutic treatment, having determined the characteristics of heterogeneous neurohumorals of metabolic syndrome, the clinical manifesto of the disease. The analysis of the study shows that the issues of pathogenesis, clinical features of improving the effectiveness of medicamentous therapy, and treatment-rehabilitation aspects have not been studied perfectly so far. In patients with metabolic syndrome, hypotensive, anti-adipose agents, as well as treatment of statins and improvement of the prophylactic order of prevention of diseases, the issues of which were not studied at the end were discussed.
The age is common risk factor for cardiovascular diseases (CVD). One of the main risk factors for ageing is biologic age of vessels or vessel ageing. Main mechanisms of vessel ageing are oxidative stress, chronic inflammation, endothelial disfunction, apoptosis of endothelial cells, demage of endothelial EPCs progenitory cells functions, replication ageing of endothelial cells, disregulation of circadian system, arterial stiffness. Understanding of the mechanisms that lead to ageing pathophyziological changes in vessels is important and necessary of for novel methods of patogenetic treatment
Aim of the research was the study activity of sympaticoadrenal system (SAS) at elderly patients with ischemic heart disease (IHD) and combinant subclinical hypothyrosis (SH) the level of daily excretion of cateholamines (CA) and activity of mo- noaminoxyase (MAO) in combination with determine activity processes of peroxide oxidation of lipids (POL). Results of examination of 28 patients with IHD and 14 patients with IHD in combination with SH were analyzed. Patients with IHD in combination with SH had the decrease of activity of SAS, which manifested by decrease excretion of CA. The maximum decrease of activity of MAO in patients with IHD and concomitant SH was detected. Also processes of POL were augmented, it was verified by increased
level of malonic dialdehyde - final substance of peroxidation. On the base of received results, it could be supposed, that decrease activities of SAS and POL are interrelated inpatient with combined pathology
This article examines the main criteria for assessing university studies. The problems faced today are analyzed. An automated system for assessing university studies has been proposed, which will allow the output of the necessary statistical data to improve the quality of education.