ISSN:
2181-3906
2024
International scientific journal
«MODERN SCIENCE АND RESEARCH»
VOLUME 3 / ISSUE 2 / UIF:8.2 / MODERNSCIENCE.UZ
537
TREATMENT AND PREVENTION OF SYMPTOMS OF DIFFUSE TOXIC GOITER
Bakhramov Shokhrukh
Primkulov Muhammad
Ergashov Otabek
Students of Samarkand State Medical University
Department of Endocrinology
Scientific supervisor:
Togʻayeva Gulnora Siddikovna
Samarkand State Medical University
https://doi.org/10.5281/zenodo.10658439
Abstract.
Diffuse toxic goiter is a pathology associated with the functioning of the
endocrine system. Its essence is that some autoimmune processes lead to an increase in the
production of thyroid hormones. Against this background, thyrotoxicosis occurs - simply put, this
is poisoning of the div with hormones produced by the thyroid gland.
Key words:
diffuse toxic goiter, symptoms, manifestations, prevention.
ЛЕЧЕНИЕ И ПРОФИЛАКТИКА СИМПТОМОВ ДИФФУЗНОГО
ТОКСИЧЕСКОГО ЗОБА
Аннотация.
Диффузный токсический зоб – патология, связанная с
функционированием эндокринной системы. Суть его в том, что некоторые аутоиммунные
процессы приводят к увеличению выработки гормонов щитовидной железы. На этом фоне
возникает тиреотоксикоз – проще говоря, это отравление организма гормонами,
вырабатываемыми щитовидной железой.
Ключевые слова:
диффузный токсический зоб, симптомы, проявления,
профилактика.
Symptoms of diffuse toxic goiter include:
increased div temperature;
increased sweating: the patient always feels hot;
cardiopalmus;
increased blood pressure;
weakness in arms and legs;
dermatological manifestations. As a result, the nails may break and the hair may fall out a
lot. Sometimes there is a change in the color of some areas of the skin and darkening of others.
Usually the integument is dark on the elbows, lower back and neck;
changes in behavior. For example, a person becomes more restless and tense.
bulging eyes (bulging eyes). This is common, but not necessary;
tears, feeling that there is something extra in the eyes (garbage, sand);
enlargement of the thyroid gland (this is called a goiter);
severe weight loss, which is especially noticeable in initially overweight people.
Often women face this disease. According to various sources, they get sick 5-6 or even 8-
9 times more often than men. There is also a dependence on the place of residence. Toxic goiter is
most actively detected in women living in big cities.
Reasons
ISSN:
2181-3906
2024
International scientific journal
«MODERN SCIENCE АND RESEARCH»
VOLUME 3 / ISSUE 2 / UIF:8.2 / MODERNSCIENCE.UZ
538
It is very difficult to say why diffuse goiter appears and endocrine diseases appear.
Currently, medicine does not have a clear answer to this question. But there are some factors that
contribute to the appearance of "toxic" goiter: heredity. It is noted that if one of the close relatives
is sick, the risk of the disease is high;
bad ecology. Obviously, this is why we often talk about large cities with more polluted air
than other settlements;
infections;
psychotrauma. Stress is also a symptom of big cities;
poor quality food. In particular, people who do not get enough iodine from food or, on the
contrary, have an excessive amount of iodine, are at risk;
other autoimmune diseases;
smoking Studies show that this problem occurs twice as often in smokers than in people
who lead a healthy lifestyle.
Usually, after talking to the patient, it becomes clear that diffuse toxic goiter is caused by
a combination of several factors.
Levels or stages
Diffuse toxic goitre There are three stages (levels) of disease development. A mild case is
accompanied by a relatively small tachycardia (up to a hundred beats per minute), as well as
anxiety.
The severe level of toxic goiter is characterized by severe fatigue, disruption of the
functioning of various organs, as well as div systems. Such a condition does not appear suddenly
- we are talking about a problem that has been ignored and has not been treated, even if we take
into account that it has manifested itself for a long time.
There are other classifications that evaluate diffuse goitre according to its size, level of
palpation, etc.
Complications and consequences
Without treatment of diffuse toxic goiter, the patient's condition is always complicated. We
are talking about pathologies of heart, blood vessels, central nervous system and gastrointestinal
diseases. In difficult situations, there is a risk of paralysis. The extreme manifestation of the disease
is a thyrotoxic crisis, as a result of which 30 to 50% of patients die.
However, do not be afraid to make such a diagnosis. If you start treatment on time and
follow all the recommendations of doctors, all div functions will be normal - the patient will live
a long and very comfortable life.
Diagnostics
Diagnostic measures to determine diffuse toxic goiter include:
visual inspection and palpation. Often suspicions about the disease appear already at the
first visit to the doctor;
tests. There is a complete list of them, but do not forget to check the TSH level, as well as
T3 and T4;
Ultrasound examination of the examined organ;
scintigraphy. This is a gamma camera study;
Thyroid scan using an MRI machine.
ISSN:
2181-3906
2024
International scientific journal
«MODERN SCIENCE АND RESEARCH»
VOLUME 3 / ISSUE 2 / UIF:8.2 / MODERNSCIENCE.UZ
539
When diagnosing diffuse goitre, it is very important not only to make a correct diagnosis,
but also to know in advance the possible complications for a particular patient. For this reason,
research is usually comprehensive.
Treatment
Diffuse toxic goiter Consult an endocrinologist for treatment of diffuse toxic goiter. This
includes:
use of various drugs. They are prescribed individually - such drugs should never be used
without consulting a doctor. In some cases, patients require outpatient treatment;
correction of nutrition. Patients are prescribed a diet aimed at controlling iodine intake;
treatment of diffuse goiter with radioactive iodine;
surgical intervention. After surgery, patients are prescribed lifelong use of certain hormonal
drugs.
Treatment of toxic goitre with traditional methods, information about which can be easily
found on the Internet, is not a suitable solution in this case. If the disease starts (and it certainly
happens without medical help), the health and life of the patient is in danger. Therefore, it is
important not to delay a visit to the doctor and seek help immediately at the first symptoms.
REFERENCES
1.
Andryev S. et al. Experience with the use of memantine in the treatment of cognitive
disorders //Science and innovation. – 2023. – Т. 2. – №. D11. – С. 282-288.
2.
Antsiborov S. et al. Association of dopaminergic receptors of peripheral blood
lymphocytes with a risk of developing antipsychotic extrapyramidal diseases //Science and
innovation. – 2023. – Т. 2. – №. D11. – С. 29-35.
3.
Farrukh S. ORGANIZATION OF DIGITALIZED MEDICINE AND HEALTH
ACADEMY AND ITS SIGNIFICANCE IN MEDICINE //Science and innovation. – 2023.
– Т. 2. – №. Special Issue 8. – С. 493-499.
4.
Asanova R. et al. Features of the treatment of patients with mental disorders and
cardiovascular pathology //Science and innovation. – 2023. – Т. 2. – №. D12. – С. 545-
550.
5.
Begbudiyev M. et al. Integration of psychiatric care into primary care //Science and
innovation. – 2023. – Т. 2. – №. D12. – С. 551-557.
6.
Bo’Riyev B. et al. Features of clinical and psychopathological examination of young
children //Science and innovation. – 2023. – Т. 2. – №. D12. – С. 558-563.
7.
Borisova Y. et al. Concomitant mental disorders and social functioning of adults with high-
functioning autism/asperger syndrome //Science and innovation. – 2023. – Т. 2. – №. D11.
– С. 36-41.
8.
Farrukh S. ORGANIZATION OF DIGITALIZED MEDICINE AND HEALTH
ACADEMY AND ITS SIGNIFICANCE IN MEDICINE //Science and innovation. – 2023.
– Т. 2. – №. Special Issue 8. – С. 493-499.
9.
Ivanovich U. A. et al. Efficacy and tolerance of pharmacotherapy with antidepressants in
non-psychotic depressions in combination with chronic brain ischemia //Science and
Innovation. – 2023. – Т. 2. – №. 12. – С. 409-414.
ISSN:
2181-3906
2024
International scientific journal
«MODERN SCIENCE АND RESEARCH»
VOLUME 3 / ISSUE 2 / UIF:8.2 / MODERNSCIENCE.UZ
540
10.
Karshiyev Z. et al. The degree of adaptation to psychogenic effects in social life in patients
with psychogenic asthma //Science and innovation. – 2023. – Т. 2. – №. D11. – С. 295-
302.
11.
Konstantinova O. et al. Clinical and psychological characteristics of patients with
alcoholism with suicidal behavior //Science and innovation. – 2023. – Т. 2. – №. D11. – С.
399-404.
12.
Konstantinova O. et al. Experience in the use of thiamine (vitamin B1) megadose in the
treatment of korsakov-type alcoholic encephalopathy //Science and innovation. – 2023. –
Т. 2. – №. D12. – С. 564-570.
13.
Kosolapov V. et al. Modern strategies to help children and adolescents with anorexia
nervosa syndrome //Science and innovation. – 2023. – Т. 2. – №. D12. – С. 571-575.
14.
Farrukh S. ORGANIZATION OF DIGITALIZED MEDICINE AND HEALTH
ACADEMY AND ITS SIGNIFICANCE IN MEDICINE //Science and innovation. – 2023.
– Т. 2. – №. Special Issue 8. – С. 493-499.
15.
Lomakin S. et al. Biopsychosocial model of internet-dependent behavior. Risk factors for
the formation of the internet //Science and innovation. – 2023. – Т. 2. – №. D12. – С. 205-
211.
16.
Lomakin S. et al. Features of electroencephalographic disorders in patients with mental
disorders due to brain damage or dysfunction //Science and innovation. – 2023. – Т. 2. –
№. D12. – С. 367-372.
17.
Farrukh S. ORGANIZATION OF DIGITALIZED MEDICINE AND HEALTH
ACADEMY AND ITS SIGNIFICANCE IN MEDICINE //Science and innovation. – 2023.
– Т. 2. – №. Special Issue 8. – С. 493-499.
18.
Lomakin S. et al. Socio-demographic, personal and clinical characteristics of relatives of
patients with alcoholism //Science and innovation. – 2023. – Т. 2. – №. D12. – С. 278-283.
19.
Lukasheva A. et al. Psychosomatic relationships in different age groups in patients with
facial dermatosis //Science and innovation. – 2023. – Т. 2. – №. D11. – С. 289-294.
