Premature menopause is a pathological condition characterized by the cessation of the functional activity of the ovaries in women under the age of 40 and manifested by amenorrhea, high levels of gonadotropins in the blood, infertility and symptoms of estrogen deficiency. POF occurs on average in 1% of women. The exact nature of the disease remains unknown. The basis of this pathology, regardless of the etiological factor, is a decrease in the reserve of primordial follicles, which is unusual for this age period, up to its complete depletion and the formation of the afollicular type of POF. This condition is described as a "multifactorial syndrome" due to chromosomal abnormalities, genetic disorders, fermentopathies, infectious and iatrogenic factors.
Absatarova Yu. S., Andreeva EN Premature ovarian failure: modern aspects of patient management // Collection of theses of the III All-Russian conference with international participation "Reproductive health of women and men". - 2018 .-- S. 5-5.
Adamyan LV et al. New possibilities of surgery in restoring the lost functions of the ovaries with premature ovarian failure in women of reproductive age // Doctor. RU. - 2019. - T. 11. - No. 166 .-- S. 44-9.
Andreeva VO, Aperyan AV, Shukhardina TA Comparative analysis of the clinical efficacy of low-dose combined oral contraceptives with drospirenone and systemic enzyme therapy in adolescents with ovarian hypofunction of autoimmune genesis // Reproductive health of children and adolescents. - 2019. - T. 15. - No. 3.
Blinov DV and others. Early menopause and premature ovarian failure: problems and prospects // Obstetrics, gynecology and reproduction. - 2020. - T. 14. - No. 3. - S. 328-345.
Ignatieva R. E., Gustovarova T. A., Dmitrieva E. V. Method for assessing the state of the ovarian reserve of the ovaries. - 2018.
Kravtsova OA et al. Sonomorphological criteria of endometrium readiness for implantation during IVF // Postgraduate readings-2017. - 2017 .-- S. 110-111.
Podzolkova NM et al. Discussion issues of clinical, laboratory and instrumental diagnosis of ovarian tumors in women of reproductive age (literature review) // Gynecology. - 2020. - T. 22. - No. one.
Solomatina AA et al. Ultrasound indicators of ovarian reserve in newly diagnosed and recurrent endometrioid ovarian formations // Russian Bulletin of Obstetrician-Gynecologist. - 2017. - T. 17. - No. 4. - S. 43-48.
Cekici Y. et al. Prediction of Lipoprotein-Associated Phospholipase A2 and Inflammatory Markers in Subclinical Atherosclerosis in Premature Ovarian Failure Patients // Acta CardiologicaSinica. - 2021. - T. 37. - No. 1. - P. 30.
Chen L. et al. Effect of stem cell transplantation of premature ovarian failure in animal models and patients: A meta-analysis and case report // Experimental and therapeutic medicine. - 2018. - T. 15. - No. 5. - S. 4105-4118.
Eleazu I. C., Jones-O'Connor M., Honigberg M. C. The Impact of Premature Menopause on Future Risk of Cardiovascular Disease // Current Treatment Options in Cardiovascular Medicine. - 2020. - T. 22. - No. 12. - S. 1-11.
Gu Y., Xu Y. Successful spontaneous pregnancy and live birth in a woman with premature ovarian insufficiency and 10 years of amenorrhea: A case report // Frontiers in medicine. - 2020. - T. 7.
Xu H. et al. Effects of Low Intensity Pulsed Ultrasound on Expression of Bax and Bcl-2 in Premature Ovarian Failure Mice Induced by 4-Vinylcyclohexene Diepoxide. - 2021.