HYPOLIPIDEMIC EFFECT OF ETHANOLIC SEED EXTRACT OF BACCAUREA RAMIFLORA IN WISTER ALBINO RATS
Keywords:
Abstract
The present study investigated the hypolipidemic effect of the ethanolic seed extract of Baccaurea ramiflora in Wister albino rats. Hyperlipidemia is a major risk factor for cardiovascular diseases, and natural plant extracts have gained attention as potential therapeutic agents for managing lipid disorders. In this study, Wister albino rats were orally administered with different doses of the ethanolic seed extract for a specified duration. The lipid profile, including total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C), was measured to assess the hypolipidemic effect of the extract.
The results demonstrated that the ethanolic seed extract of Baccaurea ramiflora significantly reduced total cholesterol, triglycerides, and LDL-C levels, while increasing HDL-C levels in hyperlipidemic rats. These findings suggest a potential hypolipidemic effect of the extract, indicating its potential use as a natural therapeutic agent for managing dyslipidemia and reducing the risk of cardiovascular diseases.
Similar Articles
-
On The Importance Of The Human Body, Nitrates
The American Journal of Medical Sciences and Pharmaceutical Research: No. 04 (2021) / Abdumuminova R.N. , Baratova R.Sh, Bulyaev Z.K., -
Diet Therapy In Food Allergy And Fungal Pathology
The American Journal of Medical Sciences and Pharmaceutical Research: No. 03 (2021) / Abdullaeva Dilafruz Gayratovna , Abdullaev Mansur Abdusattarovich , Yodgorova Nodira Turgunbaevna, -
The Intensity Of Dental Caries In Workers Is Harmful Industry
The American Journal of Medical Sciences and Pharmaceutical Research: No. 05 (2021) / Nazarova Nodira Sharipovna, Rakhimberdiev Rustam Abdunosirovich , Bakirov Asadullo Abdikodirovich, Sultonov Odiljon Raimovich, -
Hygienic Assessment Of Emission Influence From A Chemical Plant On Population’s Household Conditions, Well-Being And Health
The American Journal of Medical Sciences and Pharmaceutical Research: No. 01 (2021) / Zainab Naimova , Khurliman Kurbanova, Honbuvi Khakimova, Zokir Bulyaev, -
ANALYSIS OF DAILY ENERGY USAGE BY WORKERS IN A TOBACCO PRODUCTION FACILITY
The American Journal of Medical Sciences and Pharmaceutical Research: No. 04 (2024) / Azizova F.L, Boriboev E.M, -
AN OVERVIEW ON MULTIPATH STEERING SYSTEM IN MULTIBOUNCE REMOTE SENSOR ORGANIZATION
-
Allergy In Children With Atopic Dermatitis
The American Journal of Medical Sciences and Pharmaceutical Research: No. 01 (2021) / Klicheva T.A. , Ismailova Z.A., -
Careful Attention To The History Of Chronic Urticaria Is One Of The Important Factors Of Productive Therapy
The American Journal of Medical Sciences and Pharmaceutical Research: No. 02 (2021) / Akhmedov Shavkat Kurbonalievich , Ashirov Zohijon Fayozjonovich , Oripov Rustam Anvarovich , Siddikov Olim Abdullaevich, Haydarov Musomiddin Mukhammadievich, -
Features Of Flow Of Diseases Of The Oral Cavity In Workers Of Production Of Fiberglass Structures
The American Journal of Medical Sciences and Pharmaceutical Research: No. 10 (2020) / Jasur Ризаев Alimjanovich , Nazarova Nodira Sharipovna , Berdiev Timur Kaxorovich, -
Assessment Of Some Functional Indicators Of The Oral Cavity Working In Tobacco Production
The American Journal of Medical Sciences and Pharmaceutical Research: No. 10 (2020) / Nazarova Nodira Sharipovna , Sitora Baizakova , Sevinch Ismailova ,
References
Gupta A, Sehgal V, Mehan Hyperlipidemia: An updated review. Inter JBiopharmaceutical Toxicol Res. 2011;1:81-9.
Shattat GF. A review article on hyperlipidemia: types, treatments and new drug targets. Biomedical and Pharmacology Journal. 2015;7(1):399-409.
Rohilla A, Dagar N, Rohilla S, Dahiya A, Kushnoor A. Hyperlipidemia- a deadly pathological condition. Int J Curr Pharm Res. 2012;4(2):15-8.
Ruixing Y, Yuming C, Shangling P, Fengping H, Tangwei L, Dezhai Y, et al. Comparison of lipid levels, hyperlipidemia prevalence and its risk factors between Guangxi Hei Yi Zhuang and Han populations. Archives of medical research. 2006;37(6):787-93.
Mahamuni SP, Khose RD, Menaa F, Badole SL. Therapeutic approaches to drug targets in hyperlipidemia. BioMedicine. 2012;2(4):137-46.
Adam J. Improve cholesterol-HDL, the new paradigm dyslipidemia treatment. J Med Nus. 2005;26(3):200-4.
Damery S, Gratus C, Grieve R, Warmington S, Jones J, Routledge P, et al. The use of herbal medicines by people with cancer: a cross-sectional survey. British journal of cancer. 2011;104(6):927.
Dhaliya S, Surya A, Dawn V, Betty C, Arun K, Sunil C. A review of hyperlipidemia and medicinal plants. Int JA PS BMS. 2013;2(4):219-37.
Lin Y, Yi Z, Zhao Y. Chinese Dai medicine colorful illustrations. Kunming: Yunnan National Publishing House. 2003;380.
Sundriyal M, Sundriyal R. Underutilized edible plants of the Sikkim Himalaya: need for domestication. Current Science. 2003:731-6.
Council NR. Guide for the care and use of laboratory animals: National Academies Press; 2010.
Arafa HM. Curcumin attenuates diet-induced hypercholesterolemia in rats. Medical Science Monitor. 2005;11(7):BR228-BR34.
