Study of the influence of obesity in parentals on teething in children of the first year of life who are exclusively breastfeeded

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Даминова S., Исаходжаева X., Маликов S., & Акрамова D. (2022). Study of the influence of obesity in parentals on teething in children of the first year of life who are exclusively breastfeeded. in Library, 22(1), 86–88. извлечено от https://inlibrary.uz/index.php/archive/article/view/14499
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Аннотация

The  purpose  of  this  study  was,  based  on  the  study  of  the characteristics of hormonal and lipid metabolism in newborns and obese women, to determine the diagnostic criterion for disorders in the process of teething in children of the first year of life. The object of the study was 78 practically healthy lactating women  aged  20-27  years,  as  well  as  their  newborns.  Statistically  significant differences were found in the mean leptin concentrations, increasing in proportion to the baseline BMI, while the adiponectin level, on the contrary, was significantly low.

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STUDY OF THE INFLUENCE OF OBESITY IN PARENTALS ON

TEETHING IN CHILDREN OF THE FIRST YEAR OF LIFE WHO ARE

EXCLUSIVELY BREASTFEEDED.

Daminova Sh. B., Isahodjaeva H. К., Malikov S. T., Akramova D. K.

Summary.

The purpose of this study was, based on the study of the

characteristics of hormonal and lipid metabolism in newborns and obese women, to

determine the diagnostic criterion for disorders in the process of teething in children

of the first year of life. The object of the study was 78 practically healthy lactating

women aged 20-27 years, as well as their newborns. Statistically significant

differences were found in the mean leptin concentrations, increasing in proportion

to the baseline BMI, while the adiponectin level, on the contrary, was significantly

low.

Material and research methods.

The object of the study was 78 practically

healthy lactating women aged 20-27 years living in the city of Tashkent, as well as

their newborns. In accordance with the objectives of the study, patients were divided

into 2 groups: group 1, obese patients (38 puerperas) and group 2 of patients without

obesity (30 puerperas). The main group of the study consisted of patients according

to the criteria suitable for the diagnosis of obesity. The diagnosis was made using

data from an anthropometric study of patients, determining the div mass index.

Anthropometric examination included determination of div weight, height, waist

circumference (OT), hip volume (OB), OT / OB ratio. BMI was assessed according

to the recommendations of the WHO experts [WHO, 2000]. According to the level

of this parameter, patients with normal weight (BMI - 18.5-24.99 kg / m :),

overweight (BMI - 25.0-29.99 kg / m2) and obesity (BMI - 30, 0 kg / m2 or more).

Exclusion criteria from the study: chronic renal failure, type 1 diabetes mellitus,

severe anemia, pregnancy and lactation, cancer, respiratory failure, taking

medications that affect the level of bone resorption and gingival hypertrophy.

Research results and their discussion.

As shown by the studies, the majority

of mothers of the main group were obese (69.7 ± 5.6%), more than half (52.8 ±

5.9%) had a burdened heredity for obesity. Among the diseases associated with

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obesity, in the group of surveyed puerperas, arterial hypertension (27.8 ± 3.3%),

various variants of carbohydrate metabolism disorders (45.1%) that occurred before

or during pregnancy should be indicated. Significant perinatal outcomes of obesity

in mothers, according to our data, are the birth of children with asphyxiation (27.8 ±

2.6%, morphological and functional immaturity of newborns (26.6 ± 4.8%),

macrosomia (41.8 ± 3.4%). The incidence of macrosomia was higher in the presence

of metabolic complications of obesity in mothers, reaching 65.0 ± 10.9%. From the

point of view of the consequences, macrosomia of the fetus and newborn is

considered a risk factor.

In the course of a dynamic study of the characteristics of the hormonal profile

in the blood, statistically significant differences in the mean concentrations of leptin

were established, increasing in proportion to the initial BMI. With an increase in

gestational age, an increase in the concentration of leptin was observed. The

adiponectin level, on the other hand, was significantly low relative to the comparison

group. Thus, the results of our clinical laboratory study allowed us to identify

violations in the parameters of lipid and carbohydrate metabolism, which will allow

using these criteria in the diagnosis of disorders in the process of teething in

newborns from obese mothers.

Conclusion

.

1. In the course of a dynamic study of the characteristics of the hormonal profile in

postpartum women, statistically significant differences in the mean concentrations

of leptin, increasing in proportion to the initial BMI, were established, while the

level of adiponectin, on the contrary, was significantly low.

2. As a result of the assessment of the parameters of the lipid profile in the examined

persons, a statistically significant decrease in the level of HDL cholesterol and an

increase in the concentration of triglycerides in proportion to the increase in BMI

were established.

3. In children born to obese women, the level of C-peptide was significantly higher

than that in children of the comparison group. This is apparently associated with an

increase in the level of insulin in children of the main group in response to excessive

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glucose supply to the fetus through the placenta during hyperglycemia in the mother,

and also an imbalance in the lipid spectrum of the newborn's blood with an increase

in the atherogenic fraction was revealed

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