390
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE
“
MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS
”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
MAIN GROUPS OF BIOLOGICALLY ACTIVE SUBSTANCES OF CHICKWEED
(STELLARIA MEDIA L.)
AND THEIR PHARMACOLOGICAL SIGNIFICANCE
Saipiyeva B.S.
Sayakova G.M.
Kazakh National Medical University named after S.D. Asfendiyarov, Almaty,
Republic of Kazakhstan
e-mail: bernarasajpieva@gmail.com 8-707-716-38-02
https://doi.org/10.5281/zenodo.17339453
Relevance:
Chickweed
(Stellaria media L.)
is a widespread annual plant in the
Caryophyllaceae family, possessing a rich chemical composition. Interest in this species stems from
the presence of various biologically active substances, which determine its pharmacological activity
and potential for use in herbal medicine. However, despite this, there are no medications based on
chickweed
(Stellaria media L.)
. Studying its properties would expand the pharmaceutical market.
Study Objective
. To analyze literature data on the chemical composition of chickweed, to
determine its pharmacological action, and to identify the main groups of biologically active
substances.
Materials and Methods.
International literary sources, including data on the phytochemical
composition and pharmacological activity of chickweed components, were used. A systematic
analysis and synthesis of scientific information was used. Particular attention was paid to studies
devoted to the study of flavonoids, saponins, phenolic acids, and vitamins.
Study Results.
Based on a review of the literature, it was established that chickweed
(Stellaria
media L.)
contains a wide range of biologically active substances. The most significant include
flavonoids (rutin, quercetin, apigenin), saponins, phenolic acids (chlorogenic, caffeic, ferulic), as well
as vitamins C and E and carotenoids. The flavonoids contained in the plant exhibit pronounced
antioxidant activity, helping to neutralize free radicals, reduce inflammation, and strengthen capillary
walls. Saponins exhibit immunomodulatory and anti-inflammatory effects and also influence lipid
metabolism. Phenolic acids inhibit lipid peroxidation, protecting cells from oxidative stress. The
vitamin complex of chickweed enhances its overall tonic effect.
Evidence has also been found of the potential antimicrobial, diuretic, and wound-healing
activity of the plant's extracts, confirming its suitability for use in phytotherapeutic formulations.
Additionally, literature provides information on hypoglycemic and hypolipidemic effects, opening up
potential for the use of chickweed in metabolic disorders. The combination of these properties allows
this plant to be considered a source of natural antioxidants and complex biologically active
compounds that may be useful in the development of new drugs and dietary supplements.
Conclusion.
Thus, chickweed
(Stellaria Media L.)
is a promising source of biologically active
substances with a wide range of pharmacological properties. Further research aimed at standardizing
the content of active components and assessing their bioavailability is necessary to substantiate
medical use and develop effective dosage forms based on this plant.
