В ревматических заболеваниях основным характерным проявлениям является боль, возникающий вследствие поражения структур скелетно-мышечный системы. Вызванные метаболический, аутоиммунные, дегенеративные нарушения в патогенезе отражает воспалительным процессом. Больные ревматическими заболеваниями вынужденно регулярно принимать обезболивающие препараты, основная часть которого составляют нестероидные противовоспалительные препараты.
Every year there is an increasing interest in combined expectorant drugs. In the context of a new coronavirus infection, accompanied by the development of pneumonia, mucolytic and antitussive drugs were prescribed to almost all patients, so interest in this group of drugs has grown significantly.
Нестероидные противовоспалительные препараты очень широко применяются среди населения и они под названием анальгетики + антипиретики в аптечной сети реализуются без рецептов, и пациенты пользуются этими привилегиями. Изучение антипиретической и анальгетической эффективности и переносимости современных препаратов, взаимодействие и побочные эффекты и дозирование в детском периоде имеет свои особенности.
In Uzbekistan tuberculosis is one of the most threatening social and medical problem. Tuberculosis has become an epidemic in many countries of the world.Almost one and a half million people die annually from this insidious infection. Tuberculosis can be prevented and cured even with the most scarce resources.The article analyzes the case histories of patients who received in the threatment in the Khorezm regional anti- tuberculosis dispensary.
The treatment of obliterative diseases of the lower limb vessels remains a significant challenge in modern vascular surgery. The high frequency of postoperative complications, high mortality, and progression of atherosclerotic processes after reconstructive interventions on the vessels of the lower limbs have led to a search for pathogenetically justified ways and means of preventing complications of reconstructive surgeries.
The author employed hypolipidemic agents, namely glyrofam and colestid, to develop a conservative prophylaxis regimen for postoperative complications of obliterating atherosclerosis. The regimen was based on the study of platelet aggregation activity indices and lipid metabolism state. It consisted of a course of treatment with hypolipidemic drugs, administered in 1-month cycles with a 3-month periodicity.
The clinical material comprises the examination and treatment of 138 patients. The control group included 61 patients. The main group comprised 77 patients, 39 of whom took colestid and 38 patients used glyrofam.
The study of long-term outcomes demonstrated a reduction in the incidence of postoperative thrombosis from 8.1% to 1.3% and a decrease in mortality from 13% to 2.6% in patients undergoing hypolipidemic therapy.
These findings suggest that hypolipidemic drugs that affect lipid metabolism may prevent the progression of atherosclerotic processes and that drugs that affect the rheological properties of blood may reduce the incidence of postoperative thrombosis.
Subject of research: 128 patients with acute, subacute, secondary-chronic and primary-chronic types of Rock fever.
Aim of research: early diagnosis of audio and vestibular disturbances on patients undergo Rock fever and against background of usage of ototoxic medicines by applying of modem complex tools of audio research and impcdanccmctry.
Tools of research: general clinical research, special inquiries: examination of otolaryngologic organs, acoumctcring, tone threshold audiomctcring, voice audiometery, impcdanccmctry, detection of audio sensitivity to ultrasound under methodology of В. M. Sagalovich, vestibulometery, clcctronistagmography, reenccphalography.
Results received and their novelty: different types of audio disturbances were first time discovered from patients with Rock fever infection during a complex inquiry of audio and vestibular organs status: in acute and subacute types of Rock fever there dominate the audio disturbances on sound conductivity, in chronic type - the mixed or advantageously ncurosensoric character. There was applied an impcdanccmetry to define a character and level of injury of audio organ.
A scheme of complex conservative therapy included the mounts that influence on hemodynamics; adjuvants; the mounts that influence on tissue interchange; antyhypoxantincs that improve microcirculation of internal car; enzyme mounts that eliminate cicatrical and soldering processes in medium ear.
Practical value of dissertation: a qualified method of diagnosis of different types audio disturbances was proposed to practical public health. The methods of early diagnosis allow asserting a necessity of usage of early complex inquiries of audio and vestibular analyzers to make a prevention and development of further abnormalities (hard hearing and surdity).
A level of introduction: received results were introduced to the work of Otolaryngologic department of Second Tashkent State Medical Institute and clinical infectious hospital of Scientific Research Institute of Epidemiology, Microbiology of Infection Diseases of Republic of Uzbekistan.
Fields of applying: otolaryngology, infection diseases.
Hozirgi vaqtda jigar kasalliklarini davolash uchun ko'plab gepatoprotektiv o'simlik preparatlari qo'llaniladi. Bular: Silebor, Legalon, Norsil, LIV-52, Apkosul kabi dorilar. Ammo bu dorilar har doim ham printsiplar talablariga javob bermaydi. Shu munosabat bilan o‘simliklardan kelib chiqqan yangi gepatoprotektorlarni tadqiq etish va joriy etish zamonaviy tibbiyotning dolzarb muammolaridan biridir. Ishning maqsadi: o'simlik kelib chiqishi margali gepatoprotektorlari bo'yicha klinik tadqiqot natijalarini o'rganish va tahlil qilish.
The purpose of the study is to study the sensitivity of microbes to certain drugs in vitro! Material and Methods: to establish this research method, we have prepared 18-hour cultures of microbes - taking into account the most frequent inhabitants in the oral cavity. 1-2 ml of the studied microbes were applied to the surface of the dried nutrient medium by Mueller Hinton. The preparation sea buckthorn oil had an antibacterial effect on most microbes, although among them the most sensitive were such microbes as streptococci, proteas and pseudomonas. At the same time, the chlorhexidine drug had an effect on most microbes, but the effect was insignificant and only streptococci were the most sensitive and amounted to 18.0 ± 0.3 mm. Conclusions: the drugs used to treat sick children belonging to the group of traditional therapy have a weak antibacterial effect. At the same time, drugs from the special treatment group have a more pronounced antibacterial effect, especially on microbes of the genus streptococci.
Как известно при острых и хронических осложнениях у больных с заболеваниями пародонта наблюдаются различные аллергические реакции и расстройства на медикаментозные препараты что провоцирует патологическую реакцию в пародонте. Это ведёт к появлению болей и гиперестезий. Возникают кровоизлияния и аллергические реакции на применяемые препараты и могут обостряться заболевания пародонта. Поражения токсического характера или механические сдавления ортодонтическими аппаратами при заболеваниях пародонта определенных участков так же приводят к заболеваниям полости рта.
The presented literature review highlights the problems of fluid therapy at the present stage of development. A brief classification and history of the development of infusion therapy are given. The advantages and disadvantages of various groups of infusion drugs are highlighted. Special attention is paid to infusion preparations with the ability to eliminate damage to the lipid component of biomembranes, of which the most valuable are those with antioxidant membrane stabilizing and antihypoxant properties. The drugs developed at the Republican Specialized Scientific and Practical Medical Center for Hematology (RSNPMCH) of the Ministry of Health of the Republic of Uzbekistan are described. In conclusion, the prospects for further development in the development of new generation infusion preparations are given.
Обеспечение здоровья детей - главная задача общества. Кашель - это всем хорошо известный, но весьма сложный по своему механизму, рефлекс, направленный на восстановление проходимости дыхательных путей и одно из самых частых проявлений заболеваний респираторного тракта у детей.
В статье приведены данные по профилактике ценурозакаракульских овец для создания способов получения биосовместимых, безвредных и экологически безопасных антигельминтных средств растительного происхождения
The article is devoted to the problems of the development of Currently used antiretroviral therapy has made HIV infection a chronic controlled infection and has prolonged life and quality of life. However, any antiretroviral drug has side effects, although not on every patient and not always the same.
To assess the current state of the side effects problem of antiretroviral therapy in HIV - infected patients based on the analysis of literature data.
The following are data on the side effects of various groups of antiretroviral drugs used in the past and now, as well as some of their representatives. Antiretroviral drugs exhibit various side effects, in particular mitochondrial toxicity caused by nucleoside reverse transcriptase inhibitors (NRTIs), causing a wide range of side effects such as lactic acidosis, hepatic steatosis, myopathy, cardiomyopathy, peripheral neuropathy, pancreatitis, and possibly lipodystrophy syndrome. In general, integrase inhibitors are well tolerated and cause minimal drug interactions
The use of older antiretroviral drugs has been associated with a variety of side effects, which include lactic acidosis, hepatic steatosis, allergic reactions, myopathy, cardiomyopathy, peripheral neuropathy, pancreatitis and lipoatrophy.These side effects are less common with newer recommended ARVs. drugs. When treating, it is necessary to consider the likelihood of side effects and the possibility of their prevention.
Allergic rhinitis is a disease that is based on IgE-mediated inflammation of the nasal mucosa (caused by allergens), characterized by at least two of the following symptoms daily: nasal congestion, nasal discharge (rhinorrhea), sneezing, itching in the nasal cavity. Allergic rhinitis is often combined with other allergic diseases, such as bronchial asthma, allergic conjunctivitis, atopic dermatitis, and certainly is a global medical and social problem. Although allergic rhinitis is a serious, lifethreatening disease, nevertheless, its medical and social significance is due to its high prevalence among children, adolescents and adults, especially in combination with acute and chronic sinusitis, otitis media and bronchial asthma