The number of patients with diabetes mellitus in the Andijan region who were registered according to endocrinologists from 2000 to 2015 increased almost fourfold from 26,000 to more than 110,000 in 2016 (14). This also shows that the number of patients with various purulent-necrotic complications of diabetes mellitus also increases proportionally, in addition, there is an increase in patients with severe purulent-septic complications of these processes, with widespread, deep purulent-necrotic fasciitis [3]. Of patients in the department of surgical infection of the ASMI clinic, patients with purulent-necrotic complications of diabetes mellitus account for almost 78%, which indicates a significant increase in the number of these patients. This tendency continues and goes up every year. According to the WHO, by 2030 every 15 people will have diabetes, and by 2050 this figure will be equal to every 6 people.
One of the frequent complications of diabetes mellitus (DM) is the lesion of human blood vessels, leading to the development of diabetic foot. Literature and daily practical observation show an increase of the rate of diabetic foot (30-70%), which raises the actuality of the problem of diabetic foot treatment. This article contains data concerning the results of surgical treatment of 151 patients with diabetes mellitus complicated by diabetic foot and purulent-necrotic soft tissue inflammation. Our work presents the basic principles of treatment of purulent-necrotic complications of diabetes mellitus. The effectiveness of local application of Acerbin solution and two-stage surgical tactics in the complex surgical treatment of purulent-necrotic complications of diabetes mellitus has been proved.
The problem of treatment of pyoinflammatory diseases (PID) of the face and neck is relevant for both dentists of polyclinics and maxillofacial surgeons in hospitals. About 50% of those in maxillofacial hospitals, and about 20% of those who seek help from a dentist and a surgeon of polyclinics, are patients with inflammatory diseases of the maxillofacial region (MFO), among them - 60-80% of patients with abscesses and phlegmons, the frequency of which has increased by 1.5–2.0 times over the past decade. There has been a steady growth of atypical and severely flowing progressive phlegmon, spreading simultaneously in several cellular spaces, with the development of such formidable complications as sepsis, contact mediastinitis, and thrombosis of the cavernous sinus of the dura mater. Low-symptom “erased” forms of phlegmon are found among 13.4–22% of patients, are characterized by a long course and are difficult to diagnose, which contributes to late hospitalization and untimely treatment started. Microbial etiology of HVZ CLO is due to the localization of the primary process (connection with the oral cavity, teeth).