Hospital or nosocomial infections are the most common complication in patients in intensive care units and the leading cause of death in both surgical and somatic patients. Despite the presence of a large number of antibacterial drugs in the doctor's arsenal, the results of HI treatment remain unsatisfactory. In recent years, there has been a steady trend towards an increase in the resistance of hospital strains of microorganisms to the most commonly used antibacterial drugs in the clinic. Approximately 90% of all nosocomial infections are caused by bacteria, a distinctive feature of which is resistance to many groups of antibacterial drugs (multiresistance). This is what causes difficulties in the treatment of nosocomial infections, predetermining the low efficiency and high cost of treatment. Resistant strains form under the influence of widely and inappropriately used antibiotics at both prehospital and hospital levels. They can enter the hospital from the body of carrier patients. The transfer of bacteria from patient to patient involves the staff of medical institutions in the process of caring for patients, performing diagnostic procedures, etc. The problem of nosocomial infection, including through respiratory equipment, is very acute due to the increased development of ventilator-associated pneumonia. Along with the impossibility of ensuring the sterilization of anesthesia and respiratory equipment after each patient, there is a serious problem of effective antibacterial therapy of NPV in hospitals.
