Age-related macular degeneration (AMD) is a chronic progressive disease characterized by damage to the Central photoactive zone of the retina. AMD is one of the most common eye diseases that threaten significant vision loss and disability in people over 60 years of age. Currently, several fundamental theories of the pathogenesis of senile macular degeneration have been identified: primary aging of the retinal pigment epithelium and Bruch's membrane, oxidative stress, which consists in damage to the eye tissues due to an imbalance in the system of free radical formation and antioxidant protection, damage to the eye products, primary genetic defects, and pathological changes in the blood supply to the eyeball. AMD is a multifactorial disease, and the approach to its treatment should be comprehensive. In modem ophthalmology, bioregulatory therapy is a promising direction of pathogenetic influence. In this regard, the drug of the peptide structure "Retinalamin"is of particular interest. However, drug therapy can not always provide compensation for impaired metabolism, and its results are unstable, so physiotherapy becomes particularly relevant. Hyperbaric oxygenation (HBO) is one of the most effective and promising non-drug treatments for AMD.
Фармакология: изучение эффективности препаратов Цитиколин и Билоба в комплексном лечении возрастной макулодистрофии. Материалы и методы. Комплексное лечение возрастной макулодистрофии проведено 104 пациентам (206 глаз), из них 38 мужчин и 66 женщин. Результаты и обсуждение: в комплексном лечении возрастной макулодистрофии показан эффект от применения препаратов Ц лин и Гинко Билоба в улучшении зрительных функций, гемодинамических показателей и, в то же время, функционального состояния макулы. ! - увеличение амплитуды биопотенциалов сетчатки и оптического когерентного горла] - отразилось на улучшении состояния сетчатки.