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CHARACTERISTICS OF THE CHANGE IN THE RHEOLOGICAL
PROPERTIES OF BLOOD IN PATIENTS WITH CONCOMITANT
INJURIES OF THE BONES OF THE FACIAL SKELETON
Narmuratov B.K.
Tashkent Medical Academy
bahtiyor.normuradov1968@gmail.com
At present, the influence of the rheological properties of blood on the state of
microcirculation is generally recognized. It is known that microcirculation disorders
can lead to insufficient blood supply, tissue hypoxia and tissue dystrophy. Therefore,
we were tasked with studying the rheological properties of blood in patients with
concomitant injuries of the bones of the facial skeleton and analyzing them
depending on the functional activity of platelets, vascular wall endothelium, and the
coagulation link of the hemostasis system. In the occurrence of violations of the
rheological properties of blood, an important role belongs to a change in the
biophysical properties of erythrocytes - aggregation, deformability, orientation in
the flow.
Results.
Changes in blood viscosity, noted by us in patients with concomitant
injuries of the bones of the facial skeleton before and during the traditional course
of treatment. We revealed a statistically significant increase in blood viscosity before
treatment in patients with mandibular fractures compared with the control group at
all shear rates.
In a statistical analysis of changes in blood viscosity in a group of patients
during the course of traditional treatment (compared with the data before the start of
treatment), there was no statistically significant increase in blood viscosity on days
35 at all shear rates (p2=0.4 at 20 1/s ; p2 = 0.5 at 100 1 / s; p2=0.34 at 200 1/s) and
a significant decrease at the time of discharge of patients (p2=0.02) only at a shear
rate of 20 1/s. Complete restoration of blood viscosity at all shear rates in patients
with combined injuries of the bones of the facial skeleton does not occur during
traditional treatment, as evidenced by the presence of a statistically significant
difference in the value of blood viscosity on days 10-12 of treatment and the data of
a control group of practically healthy people. In patients with concomitant injuries
of the bones of the facial skeleton, before the start of treatment, there was a
statistically significant increase (p 1=0.09) in the aggregation of erythrocytes and a
decrease (p1=0.01) in the deformability of erythrocytes compared with the control
group. In the course of the treatment, the erythrocyte aggregation index does not
statistically significantly change on days 3-5 (p2=0.61) and on days 10-12
(p2=0.059) in comparison with the data before treatment. At the time of discharge,
IAE is equal to 1.29±0.18 conventional units, which is higher than in the control
(1.3±0.08 conventional units), but the se data are not reliable (p1=0.59). Thus, the
restoration of erythrocyte aggregation to the level of practically healthy people from
the control group occurs only by 10-12 days.
The index of deformability of erythrocytes in patients with combined injuries
of the bones of the facial skeleton on admission is statistically significantly reduced
(p1=0.01) compared with the control and is 1.03±0.02 conv. units. There was no
299
statistically significant change in the course of treatment on days 3-5 (p2=0.07) and
10-12 (p2=0.41) compared with the data at the time of admission. At the time of
discharge from the hospital, there was no complete recovery of the IDE, it remained
significantly (p1=0.01) lower than the value of healthy people in the control group
(1.09±0.05 conventional units).
Thus, in patients with combined injuries of the bones of the facial skeleton,
the syndrome of increased blood viscosity, increased aggregation of erythrocytes,
and a decrease in erythrocyte deformability are determined. In the process of treating
patients, there is no complete recovery of indicators characterizing the rheological
properties of blood.
Bibliography:
1.
Каюмова, Н., Хасанов, Ш., Хаджиметов, А., & Жилонова, З. (2021).
Оценка гематологических показателей крови у практически здоровых лиц и
больных острым гнойным одонтогенным оститом.
in Library
,
21
(2), 19–22.
извлечено от
https://inlibrary.uz/index.php/archive/article/view/13594
2.
Сувонов,
К.
(2020).
Особенности
микробного
пейзажа
периферической крови и перитонеальной жидкости при экспериментальной
кишечной непроходимости.
in Library
,
20
(2), 187–189. извлечено от
https://inlibrary.uz/index.php/archive/article/view/13977
3.
Суванов K., Халманов B., Эшмаматов I., & Камалитдинов A. (2022).
Ғиз бўшлиғида поносимон нуқсони бор беморларда микробиологик ва
иммунологик
холати.
in
Library
,
22
(1),
1–2.
извлечено
от
https://inlibrary.uz/index.php/archive/article/view/13992
ЧАСТОТА ВСТРЕЧАЕМОСТИ ВОСПАЛИТЕЛЬНЫХ
ЗАБОЛЕВАНИЙ ПАРОДОНТА У БОЛЬНЫХ С ПЕРЕЛОМАМИ
НИЖНЕЙ ЧЕЛЮСТИ
Нормуродов М.Т.
Ташкентский государственный стоматологический институт
Актуальность.
Возрастной состав пострадавших с переломами
челюстей в большинстве случаев 20-40 лет (до 70%), т.е. наиболее
трудоспособная часть мужского населения. По данным ВОЗ в данной
возрастной группе очень высок уровень заболеваний пародонта. По данным
разных авторов, в возрасте 35-40 лет он составляет от 60 до 98% случаев.
Воспалительные заболевания пародонта, как правило, сопровождаются
общими и местными нарушениями иммунитета, кровообращения и
иннервации.
Цель работы.
Изучить частоту встречаемости заболеваний пародонта с
учетом их степени тяжести у больных с переломами нижней челюсти при
неосложненном течении и в случае развития гнойно-воспалительных
осложнений - нагноения костной раны, мягких тканей, травматического
остеомиелита, а также влияние воспалительных заболеваний пародонта на
заживление костной раны.
