All articles - Gastroenterology and Hepatology
Number of articles: 704
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HYPOACID STATE OF THE GASTRIC JUICE IN CHILDREN AS AN ESSENTIAL RISK FACTOR OF ECHINOCOCCOSIS INFECTIONThe study presents the acidity of gastric juice in 389 children with echinococcosis, as well as in 133 members of their families from 42 households. All children with echinococcosis were operated on in the 2nd clinic of Samarkand State Medical Institute. The nature of the acid-forming function of the stomach in the general population of children was studied on the basis of a survey of 60 healthy children. Studies of the acid-forming function of the stomach showed that echinococcosis in 81.7% of children is associated with a hypoacid state of gastric juice.
Journal of hepato-gastroenterological research -
PROSPECTS FOR THE USE OF BETAIN, GLUCURONIC ACID AND NICOTINAMIDE, AS AN INTEGRAL PART OF THE COMPREHENSIVE TREATMENT OF RECURRENT HEPATIC HYDATID CYSTSThe article presents modern views on the etiology, pathogenesis and treatment of recurrent hepatic hydatid cysts. The toxic effects on the liver of drugs of the Albendazole group are considered. Modern views on the hepatoprotective effect of trimethylglycines are considered. Recommendations are given.
Journal of hepato-gastroenterological research -
THE ROLE OF POLYMERASE CHAIN REACTION IN THE DIAGNOSIS OF ENTEROVIRUS INFECTION IN PATIENTS WITH MANIFESTATIONS OF ACUTE INTESTINAL INFECTIONResults of a laboratory research of 170 patients with acute intestinal infection regarding identification of enteroviruses are presented in article. It was taped that an appreciable part of acute intestinal infection is presented AII to an enteroviral etiology. Features epidemiological features and a clinical picture of a disease were defined.
Journal of hepato-gastroenterological research -
THE EFFECTIVINESS OF DIET THERAPY FOR PATIENTS WITH CHRONIC HEPATITIS IN ENVIRONVENTALLI UNFAVORABLE ARAL AREASIn consideration of national traditions of Uzbek and Khorezm cooking, also take account their domestic specific nutrition designed and recommended for practice in patients with chronic hepatitis new version of ration- diet №5Khz (Khorezm).
Journal of hepato-gastroenterological research -
MORPHOMETRIC CHARACTERISTICS OF THE ULTRASONIC ANATOMY OF THE YELLOW SACKS AS A FACTOR OF FETAL LOSSThe article provides data on the study of the size of the yolk sac of pregnant women with antiphospholipid syndrome up to 8 weeks of pregnancy. Studied ultrasound anatomy, the nature of development in the early gestational period. In case of a violation of pregnancy, the yolk sac in the first trimester is characterized either by other sizes, or not determined. The diameter of this extraembryonic organ is one of the criteria that allows you to assess the state of the developing fetus.
Doctor's Herald -
ROLE OF DIFFERENT ENDOSCOPIC STUDIES IN DIAGNOSTICS AND TREATMENT OF EROSIVE AND DYSPLASTIC CHANGES IN THE MUCOSA OF THE ESOPHAGUSThe development of modem medicine is reflected in all areas. This article also presents the results and the importance of using various endoscopic studies in the diagnosis and treatment of erosive and dysplastic pathologies of the esophageal mucosa, which is one of the urgent problems of medicine. Our research is based on the tactics of diagnosis and treatment of 2051 patients with gastroesophageal reflux disease complicated by various erosive pathologies of the esophageal mucosa, examined in the period 2019-2020 in the diagnostic departments of the Samarkand CMO and State Institution “RSSPMCS named after acad. V.Vakhidov".
Doctor's Herald -
uieeuing occurs not oniy wnn ordinary uicers. oui ai me same lime otner complications sucn as uicer malignancy can develop, in which the choice of surgical tactics places great responsibility for saving the patient's life. Operation gastrectomy is one of the most extensive operations, which is divided into many complex stages and can develop various formidable complications. The article analyzes the clinical data of 6 patients operated on in the surgical departments of the Samarkand branch of the RSCEMP for bleeding from malignant stomach ulcers. -
REVIEW OF RECOMMENDATIONS FOR BREAST FEEDING INFANTS IN THE PANDEMIC COVID-19 PERIODNutrition of children is a very delicate and responsible topic. In the early stages of life, the baby needs breast milk, because only breast milk can provide the baby’s growing body with all the nutrients and protect it from various diseases in the future. In the context of the COVID-19 pandemic, many questions arose for doctors regarding the diagnosis, treatment and prevention of the disease, in particular, how should the nutrition of newborn children be carried out, as well as what still outweighs the choice of this or that approach: the risk of infection of the child or the benefits of breastfeeding? There is increasing evidence in the literature that COVID-19 can be transmitted vertically from mother to newborn. This article discusses recommendations on breastfeeding for mothers with the status of COVID-19 in developed foreign countries of the world, including in Uzbekistan.
Journal of hepato-gastroenterological research -
FEATURES OF MORPHOLOGICAL CHANGES OF A STOMACH AT SMOKING "NAS" SICK OF A CHRONIC GASTRITIS TOBACCOResearch is spent at 60 patients with stomach ulcer disease. As a result of researches shows that degree of expressiveness and weight of structural changes, depth and prevalence of process are closely connected with smoking “nas’’.
Journal of hepato-gastroenterological research -
CLINICAL MANIFESTATIONS OF GASTROINTESTINAL TRACT DISEASES IN THE ORAL CAVITY IN CHILDREN OF BUKHARAThis article describes changes in the state of the oral cavity at the pathology of the digestive system, shows the main clinical manifestations of these processes and their relationship. The information presented in the work emphasizes the advisability of including the results of a dental examination in a medical record, which will optimize the work of both pediatric dentists and pediatricians.
Doctor's Herald -
GENOTYPES OF SALMONELLA RESISTANCE ISOLATED FROM PATIENTS WITH OKA AND FROM BROILER CHICKEN CARCASESSalmonellosis is unmatched in its epidemiological complexity and difficulty in controlling it. The biology of salmonella serovars varies so widely that it inevitably makes it difficult to discuss issues related to salmonellosis, the ways and mechanisms of infection with Salmonella and contamination with Salmonella. At the end of the 20th century, a significant contribution to the spread of multiple resistance in many countries was made by the epidemic spread of multidrug-resistant strains of S. Typhimurium 104, which caused diseases in humans and were isolated from animals. We examined 31 samples from carcasses of broiler chickens and 40 strains of Salmonella isolated from patients with acute intestinal infections, hospitalized in the clinic NIIEMIZ MH RUz. Having carried out genotyping of Salmonella spp strains isolated from patients with AEI and from carcasses of broiler chickens, we see a variety of resistance genes, however, the resistance genotypes isolated from the carcasses of broiler chickens bla NDM-1, CTX-M, -TEM, -SHV, which amounted to 6.5 %. These strains carry a gene resistant to antibiotics belonging to the reserve group - carbopenems (imipenem).
Journal of hepato-gastroenterological research -
INNOVATIVE METHOD FOR DIAGNOSTICS AND TREATMENT OF SECONDARY CHRONIC PYELONEPHRITIS IN CHILDRENThe proposed modified treatment helps prevent renal inflammation, frequent recurrence and the formation of renal failure. Objective: to evaluate the modified treatment of chronic pyelonephritis in children. Material and methods. We examined 85 children with chronic secondary non-obstructive pyelonephritis developing against the background of dysmetabolic disorders (oxalate crystalluria) at the age from 4 to 15 years. The patients were divided into 2 groups depending on the methods of therapy used. Group I included 48 children who received traditional methods of treatment. Group II - 37 patients who received modified treatment (antibiotics were administered regionally lymphotropically in combination with viferon and vitamin A). Results and discussion. The study of urine cytokines, depending on the method of chronic pyelonephritis therapy, showed that in children of group I, before discharge from the hospital, the amount of IL-1, IL-6, IL-8, IL-10 in urine remained elevated (P1> 0.1. Conclusions: In CP in children, there was an increase in pro-inflammatory (IL-1, IL-6, IL-8) and a decrease in anti-inflammatory cytokines (IL-10) in the urine.
Journal of hepato-gastroenterological research -
Were comprehensively examined 50 children with obesity and hypertension. It was revealed that this category of children is tall, accelerated the rate of sexual development, a decrease in the quality of life and a high frequency of pathology from the cardiovascular system in the form of functional disorders and increased blood pressure. Biochemical studies have shown that in one third of children with abdominal obesity, the pathology of carbohydrate and lipid metabolism was observed, which was accompanied by an increase in the level of uric acid in the blood. -
CHOICE OF SURGICAL TACTICS OF TREATMENT OF PATIENTS WITH ACUTE PARAPROCTIVITIS303 patients with different forms of acute paraproctitis were treated. All patients have undergone a radial operation. The treatment tactics and surgical method was different in patients with various clinical forms of acute paraproctitis, which deponded on localization of pyogenic abscess, primary purulent motion toward anal sphincter fibers, degree of development of cicatrical process in pararectal tissue of rectum wall. The designed complex of tactical and medical actions allow to reduce the time of staying in hospital, considerably decrease percentage of relapses, improve the functional results of treatment
Journal of hepato-gastroenterological research -
THE INFLUENCE OF THE HEALTH STATE OF A NURSING WOMAN ON THE MICROELEMENTAL COMPOSITION OF MOTHER'S MILKPurpose of the study. Study of the content of microelements in breast milk to clarify the indirect dependence of the health status and morbidity of children depending on the health status of the mother and the biogeochemical conditions of the place of residence. Material and methods. 400 mothers and 400 children were examined by questionnaires. Determined the content of 22 elements in breast milk in 69 lactating women using atomic absorption and neutron activation analysis. Results. In mothers, risk groups are identified - the presence of many signs of dysmicroelementosis, the cause of which is the mother's unbalanced nutrition, a low level of culture, and a violation of nutritional rules. The content of macro- and microelements in breast milk varies greatly. Our data can be used as standard indicators for the content of 22 macro- and microelements in breast milk in the Samarkand region of the Republic of Uzbekistan. Conclusions. Conducting a multielement analysis of breast milk makes it possible for a nursing mother to promptly recommend preventive measures for micronutrient deficiency, as well as monitor the condition and corrective measures for the baby if there are signs of micronutrient deficiency.
Journal of hepato-gastroenterological research -
ALGORITHM OF INTEGRATED HEALTH STATE OF CHILDREN OF CHILDREN, TAKING INTO ACCOUNT MICROELEMENTAL IMBALANCES IN THE SYSTEM "MOTHER - CHILD"The aim of the work is to study the state of health of the child depending on the state of health of the mother, taking into account the deficiency of micronutrients, through a questionnaire and a comprehensive examination of the state of health of the mother, followed by the development of an action plan for the provision of medical and social assistance to prevent micronutrient deficiency. 465 mothers and their children in 6 districts of the Samarkand region. In mothers during pregnancy, it was revealed: anemia - 67.9%, toxicosis - 64.2%, threatened condition - 27.3%, increased blood pressure - 25.5%, 57.6% use of various medications - 57.6 %. chronic diseases - 19.4%; during the feeding period were noted: little use of grain and legumes - 61.2%, vegetables, fruits and herbs - 60%, dried fruits, fruit juices up to 68%, milk and dairy products - 55.8%, meat products - 60.6 %, fish products - 75.6%; frequent use of refined sweets - 85.7%, tea up to 100%, as well as insufficient provision of the family in 44.2%, low knowledge of caring for a child in 52.1% of mothers. An action plan has been developed consisting of three stages.
Journal of hepato-gastroenterological research -
ACUTE BILIARY PANCREATITIS AND FEATURES OF ITS COURSE DEPENDING ON THE TACTICS TAKENThe authors conduct a comparative analysis of the severity of the condition of patients with acute pancreatitis and the reasons for the unsatisfactory outcome of the tactics of treatment of acute pancreatitis of biliary etiology - 438 patients from the total sample of patients according to the Ranson and APACHE II rating scales. The authors conclude that the dynamics of the severity of acute biliary pancreatitis during treatment is characterized by the possibility of progression of the pathological process with a significant increase in the proportion of destructive forms of the disease from 16.5% upon admission to 33.8% (p <0.001), including an increase in sterile from 13, 9% to 21.9% and infected from 2.5% to 11.8% pancreatic necrosis (p = 0.027) with various purulent-septic complications.
Journal of hepato-gastroenterological research -
MODERN TACTICAL APPROACHES IN THE TREATMENT OF TRAUMATIC LIVER INJURIESThe proposed active multi-stage surgical tactics as "damage control" in severe traumatic liver injuries in SFRNTSEMP has been used since 2006 as the only method of saving the lives of patients with severe traumatic liver injuries of IV and V degrees (according to E. Moore, 1986). In emergency surgery departments SFRNTSEMP for 2008-2018 operated 127 victims with liver injury. Among the 19 (14.96%) victims, severe liver injuries of IV and V degree of damage according to E. Moore were observed. The effectiveness of multi-stage tactics was assessed by the level of mortality and the number of purulent-septic complications. The results of surgical treatment of 19 patients with severe liver injuries, the age of patients from 17 to 50 years were analyzed. The median age was 26 years. There were 11 men and 8 women. The average assessment of the severity of damage on the ISS scale was 34 points (17-76), according to E. Moore IV and V degree of damage. The average blood loss was 2850 ml (1750-3850 ml). All patients underwent a multi-stage laparotomy with gauze (film) tamponade, the average number of operations per 1 person 2.7 (2-5), suturing the liver wound with tamponade (13), extensive hepatotomy and vascular ligation (3), atypical resection (2), stitching large main vessels with taponade (1). The average bed / day in the intensive care unit is 13 (3- 16) and the average bed / days in the clinic is 25 (3-28). Mortality was 26.3% (5 out of 19), mainly purulent-septic complications and multiple organ failure. Multi-stage active surgical tactics "damage control" in isolated and combined severe liver damage is an effective method in unstable patients with the risk of coagulopathy and multiple organ failure. The use of the "damage control" technique helped to reduce the mortality rate from severe liver injuries by 26.3%.
Journal of hepato-gastroenterological research -
THE SYNDROME OF ABDOMINAL HYPERTENSION WITH CONCOMITANT ABDOMINAL INJURIESAs is known, intra-abdominal hypertension develops as a result of severe closed trauma of the abdominal organs, inflammation of the peritoneum, severe pancreonecrosis, as well as other diseases of the abdominal organs and after surgical interventions. Intra-abdominal hypertension syndrome is a symptom complex that develops as a result of increased pressure in the abdominal cavity and proceeds with an increase in signs of multi-organ failure. In 2008-2018, the study of intra-abdominal pressure in 76 patients with concomitant abdominal trauma was carried out in SFRNCEMP. The age of the studied victims ranged from 18 to 70 years (30,5_+8,9), while most of the victims were persons of working age (up to 50 years), mainly men (n=61). In 37 (48.6%) of the victims, combined abdominal injuries were accompanied by TBI. The cause of injury in most cases was a traffic accident (n=61-80, 2%), in 10 (13.1%) – an illegal injury, in 7 (9.2%) catatrauma. Alcohol intoxication was observed in 41 (53.9%). In those patients in whose cases the operation is completed by suturing the abdominal wound tightly, there is a high risk of developing IAD and a high probability of developing intraabdominal hypertension syndrome (SIAG). In the same group of patients, signs of organ failure are significantly expressed, one of the causes of which may be increased intra-abdominal hypertension. SIAG is a rather unfavorable complication in terms of prognosis Intraabdominal pressure greater than 12 mmHg. mortality is a "borderline" indicator, the increase of which leads to an increase in mortality.
Journal of hepato-gastroenterological research -
SELECTION OF MEDICAL TACTICS IN PATIENTS WITH CIRRHOSIS OF THE LIVER IN A LONG PERIOD AFTER PORTHOSYSTEM SHUNTINGThe development of common approaches to the treatment and rehabilitation of patients with cirrhosis is based on the etiopathogenesis of liver diseases and the systematization of existing knowledge. A rehabilitation program in patients with cirrhosis after portosystemic shunting should be aimed not only at improving survival, but also improving the quality of life of patients. In this article, the authors tried to set out the main directions and standards for the rehabilitation of patients with cirrhosis after portosystemic shunting.
Journal of hepato-gastroenterological research -
ENDOSCOPIC MONITORING AND ENTERAL NUTRITION IN BURNED PATIENTS WITH GASTROINTESTINAL TRACT DYSFUNCTIONSSamarkand branch of republican research centre of emergency medicine, Samarkand, Uzbekistan In carrying out this work, we based the results on the assessment of lesions of the stomach and duodenum in burned patients, according to the endoscopic research method, which allows a more accurate assessment of the state of the mucous membrane of the stomach and duodenum. We examined 87 patients who received probe nutrition, with a lesion area of 25 to 35% of the body surface. Combined therapy in seriously ill people with the inclusion of probe hypclcmcntation can reduce the severity of exhaustion, effectively correct metabolic disorders of the gastrointestinal tract, provide a sufficient amount of plastic material, thereby reducing the number of complications of burn disease and improve the results of surgical treatment.
Doctor's Herald -
POSSIBILITIES OF APPLYING MINIMALLY INVASIVE TECHNOLOGIES IN TREATMENT OF SEVERE ACUTE PANCREATITISTo explore the possibilities of laparoscopic methods in the surgical treatment of severe acute pancreatitis, were selected two groups of surgical patients, depending on the method of surgery that were produced various types of open and laparoscopic operations. To assess the effectiveness of the applied treatment methods, in the postoperative period, we used the following laboratory and physiological parameters: progression or regression of a systemic inflammatory response syndrome (SIRS), pO2 level, neutrophil-lymphocyte ratio (NLR), as well as integrated scales of severity Ranson, APACHE II and BISAP. These results demonstrate the advantages of laparoscopic surgical procedures.
Journal of hepato-gastroenterological research -
RESULTS OF SURGICAL TREATMENT OF PATIENTS WITH ACUTE GANGRENOUS - NECROTIC PARAPROCTITISThe article discusses the results of treatment in 767 patients operated on in the proctology department of clinic № 1 of SamMI in the period 2005-2020, among whom patients with necrotic forms of the disease accounted for 36 (4.7%) patients. Among them, 731 (95.3%) had an aerobic etiology of lesions of peri-rectal tissue. The average age of the patients was 63.1 ± 4.9 years. The research results showed that a timely and radical operation, supplemented with antibacterial and detoxification therapy, led to recovery.
Journal of hepato-gastroenterological research -
SURGICAL TREATMENT OF PATIENTS WITH GАNGRENOUS FURNIERResults of surgical treatment of 13 patients with scrotum gangrene (Fournier's disease) admitted to the proctology department of the 1st SamMI Clinic are observed in the article. The early diagnostics and active management are used for radical surgical treatment of the purulent necrotic focus in combination with necrectomy in step-by-step maneuver. Complex system of the local treatment of the wound, purposeful and multiple component correction of systemic and metabolic disorders of the homeostasis are the real way to improve treatment results.
Journal of hepato-gastroenterological research
