Both nephrologists [Vasilyeva M.P. et al., 2015; Mukhin N.A. et al., 2015], and cardiologists [Кuo-ChengLue.a.,2014 ] recognized the fact that most of the currently known risk factors for cardiovascular disease (hypertension, obesity, diabetes mellitus, dyslipoproteinemia, microalbuminuria, etc.) are also risk factors for chronic kidney disease (ChKD). An inverse relationship, i.e. the influence of renal pathology on the frequency of cardiovascular disease detection has been established [Galushkin A.A. et al., 2013]. This fact is especially relevant in disorders of uric acid (UA) metabolism, as the recent literature data indicate a significant role of UA in the development of cardiovascular diseases. However, these issues are intensively studied in therapeutic practice, but they are certainly relevant for pediatric practice [M.S.Ignatova, 2011; VyalkovaA.A.,2012].
Rovda Y.I., Kazakova L.M., Minyaylova N.N. Metabolic anomalies in children: arthritic diathesis; hyperuricemia and associated diseases (gout, urate nephropathy, arterial hypertension, metabolic syndrome, type 2 diabetes) // Textbook. - Kemerovo. - 2008, p. 4-5.
Kazak S.S. Acetonemic syndrome in children / S.S. Kazak, G.I. Beketova // Nova Med. -2003. - С. 58-61.
Sapa Y.S. Syndrome of cyclic acetonemic vomiting. // Zdorov'e Ukrainy. - 2001p.-number 7.-p.31-38.
Ivanov I.V., Filippova G.M. et al. Syndrome of acetonemic vomiting in children with acute intestinal infections // Materials of the All-Russian Scientific-Practical Conference "Therapy of infectious diseases in children: current views and unresolved issues", Proceedings, St. Petersburg, 2005. -с.56.
УДК 616.36-008.331.1-005.6-053.2-089
A.T. Khaziev, S.D. Kashirin, A.A. Mikhanoshina.
Altai State Medical University Barnaul, Russia