In recent years, doctors of ultrasonic diagnostics and cancers began to pay attention to
the possibility to obtain information about the status of the cervix, especially with the aim
of assessing the prevalence of tumor process, which is especially important in planning
treatment. However, the information to date is fragmented and based on a small number
of publications. However, to date not clearly developed sonographic criteria for cervical
cancer, given the clinical course of the disease and possibilities of modern digital (digital)
ultrasonic equipment, transvaginally, color echocardiography to better identify cervical
pathology, which will improve timely, differential, and clarifying the diagnosis of cervical
cancer.
To study the characteristic features of local and systemic immunity in patients with acute purulent odontogenic ostitis of the jaw. Material and methods: The data obtained during the examination and treatment of 42 patients aged from 7 to 9 years with acute purulent odontogenic ostitis who applied to the TGSI clinic were analyzed.Results: Bacteriological study of wound discharge in patients with acute purulent odontogenic ostitis showed that staphylococcus form the basis of microflora in species ratio. These microorganisms accounted for 82% of the total number of isolated strains. Conclusions: in acute purulent odontogenic ostitis, the ability of periodontal cells to recover is not observed, but rather the development of irreversible processes occurs, which requires surgical intervention and appropriate pharmacological correction.
On the basis of the eye department of the TashPMI clinic, a retrospective study of the case
histories of 42 (84 eyes) patients with congenital cataracts was carried out. The age of the patients
ranged from 1 month to 13 years. All patients underwent a comprehensive clinical, ophthalmological, laboratory and instrumental examination and consultations of related specialists. The reasons for the late surgical treatment of children with congenital cataracts are: late diagnosis associated with clinical
forms of cataracts that are difficult to detect during external examination, the presence of concomitant somatic pathology, which is a contraindication to surgical treatment.
The lack of understanding of bilateral breast cancer is a much more complex problem for oncologists. Today the incidence of unilateral as well as bilateral breast cancer is much higher than 10 years ago, which makes this problem even more urgent. Information about the causes of bilateral breast cancer, important criteria for the development of the disease, early diagnosis of the disease and early detection of the possibility of bilateral metachronous cancer, as well as preventive measures are not fully covered in the literature, scientific studies. In this article, the authors analyze the data of the recommendations of the international scientific society and the results of large clinical trials on bilateral breast cancer. Also, important criteria in the development of metachronous and synchronous breast cancer were analyzed, the results of clinical and morphological, immunohistochemical aspects were studied. The reasons for the development and modern knowledge about the diagnosis of bilateral breast cancer have been studied. In particular, the authors reviewed and studied about 40 foreign and domestic scientific works devoted to this problem.
AIM: To analyze clinicofunctional and echobiometric indicators of the eyes in children with target refraction, pseudofacial myopia, and their mothers.
MATERIAL AND METHODS: In the eye department of the clinic of the Tashkent Pediatric Medical Institute, a correlation analysis of optical and echobiometric indicators was conducted in 30 children (30 eyes) with artifakia and their mothers (60 eyes). Visiometry, keratorefractometry, and ultrasound examination (A/В scan of the eyeball) were conducted. Children were examined 12-14 months after CC extraction with intraocular lens (I0L) implantation.
RESULTS: A strong direct correlation was determined between the optical power of lOLs in children and their mothers who were theoretically planned for I0L implantation of lOLs in the group that has achieved target refraction. This may indicate the possibility that the child has the same optical power as the mother and the optical power of lOLs in a child is the same as that in adults. No correlation was found between the optical power of the I0L in the eyes of children with pseudophakic myopia and maternal artificial lenses theoretically planned for implantation.
CONCLUSION: The direct strong correlations between the optical power of the I0L of children and the lenses of their mothers in the group with the target refraction achieved by this age make it possible to use the optical power of maternal lenses as a “guideline" when calculating the power of the I0L implanted in children to achieve the target refraction. The lack of correlation between the refractive powers of the I0L in children with pseudophakic myopia and the lenses of mothers may indicate that the SRKII formula with age-related hypocorrection is not adapted to calculate the I0L power in children at risk of excessive refractive enhancement after surgery.
To study the anti-inflammatory and some other pharmaco- logical properties, toxicity of the new thiocarbamate and thiourea derivatives (codes UB-421 and BIK-15, respectively), selected after the scrinning reseaches among the compounds of this group and to ground the possibility of their using in clinic
Caesarean section (CS) is an operative method of delivery that is widely used at the moment. According to the Ministry of Health for 2022, we registered 932.2 thousand births, which is the highest figure since independence. The total fertility rate (number of births per 1,000 inhabitants) was 26.2 – in 2022, which falls into the category of countries with a “moderately high” fertility rate. The frequency of surgical births in Uzbekistan is about 23% of all births. The purpose of the study was determined the role of the level of type XXVI collagen in the blood and its influence on the viability of the surgical scar, to improve the tactics of managing women after cesarean section. 103 pregnant women and the outcomes of their births were studied. Research and scientific work were carried out for 2020-2022. on the basis of the obstetric department of the multidisciplinary clinic of SamSMU. The average concentration of type XXVI collagen in the main group during pregnancy was 328.22±17.5 ng/ml, and after childbirth - 363.1±48.4 ng/ml, while in the comparison group there was a two-fold decrease. This shows its specificity to the organs of the reproductive system, as well as its role in assessing their condition, including the condition after a surgical scar.
In 4 years, 2,375 children with various pathologies were admitted to the Department of Plastic Surgery of the clinic of the Tashkent Pediatric Medical Institute, for make plastic surgery operation. Among them, 6 children were operated
with a diagnosis of macrostomy.
Acute inflammatory polyradiculoneuropathy (Guillain-Barre syndrome) is a severe autoimmune disorder that affects the peripheral nervous system. A clinical case with acute inflammatory polyradiculoneuropathy in a 13-year-old girl is presented. The issue of the relationship between GBS and K19 is debatable (there was contact with sick parents, there was no clinic and diagnosis of the disease (PCR) in the child, although the child had an acute respiratory infection, possibly K19, erased or mild form).
Immunological mechanisms play the leading role in the pathogenesis of inflammatory destructive processes in periodontium. That's why clinical manifestations of chronic generalized periodontitis depend not so much on pathogenicity and virulence of corresponding microflora but on the character of bacterial-gostal interrelations, that is, in many respects - on the degree of macroorganism reactivity, which is determined by the functional state of immune system. Consequently, an important step in understanding the nature of inflammatory periodontal diseases is the study of those immunological factors (cytokines and antibodies) as well as enzymes that can cause shifts in the morpho-functional state of the supporting apparatus of the tooth, as well as cause the corresponding clinic of the indicated pathology.
Purpose of the study. To study risk factors for the development of complications in pseudophakic eyes. Material and methods. We carried out a retrospective and prospective analysis of the case histories of 65 children (65 eyes) diagnosed with pseudophakia, who were in the hospital in the eye department of the clinic of the Tashkent Pediatric Medical Institute over the past 5 years. The results of the study showed that the most significant risk factors for the development of intra- and postoperative complications are the following factors: FAI, neutrophil- leukocyte index (0.94±0.5), true intraocular pressure 20.5±1.2 mm Hg. Art., thickness of the choroid 1.02 ± 0.33 mm, protein in the CV above 3.5 ± 0.09 g/l, and in the blood below 62 ± 1.3 g/l
For the first time on a large clinical material, the results of the study of clinical and morphological features and prognostic factors of clear cell ovarian cancer and mixed malignant neoplasms of the ovaries with a mandatory clear cell component are presented.
Based on a comparative analysis of pure and mixed forms of clear cell neoplasms of the ovaries, their morphological signs and features of the clinical course of the disease were established.
The factors of prognosis of malignant clear-cell neoplasms of the ovaries were revealed: the stage of the disease, the volume of surgery, the degree of tumor differentiation and the degree of cellular anaplasia.