World perception - a larval condition, which defines readiness to realization worldoutlook to activity, and which is expressed by mutual contact with external ambience on the base of the beliefs about the world and about itself, social rates and valuables. The Model world perception consists of motivation, profound and operation component. World understanding is built on the base world sensation and world perception. The Particularity world understanding on measure of the shaping the science all more open through got by her knowledges. The Sense world understanding consists of that that he is a foundation of the development of need and outlook of the person, his(its) judgements about rate and value, and naturally and argument to activity. Shaping and improvement world sensation, world perception and world understanding leads to growing of efficiency to essence of the worldoutlook and increasing of power of the influence him(it) on active life.
The Cold War was not only traditional in international relations next phase of the struggle for world domination, but also an ideological war aimed to impose on the opposing powers a certain value system, social structure, political regime, etc. As a result the ideological conflict of the opposing powers became an important component of the Cold War. With the end of the Cold War the problems of «end of history» and the “end of ideologies” were actualized on the West. It became about an axiom that the world politics lost its ideological dimension. In fact, however, ideological component is deeply integrated into the emerging «new» world order. Even the dominance of Western countries in the emerging system of international relations was legitimated by the postulates of neo-liberalism. The coming to power in the USA of president D. Trump and changes in American foreign policy stress a deep transformation in the modern system of international 51 relations. Unconditional dominance of the liberal paradigm in global scale is gradually coming to an end. This process is accelerated due to the completion of the «unipolar moment» in world politics and process of step by step formation of a polycentric world order. The world is entering to a turbulent era. And one of its main features will probably be decline of ideology influence and the strengthening of political realism as an intellectual dominant in making decisions in dynamic and unclear international environment.
In the modern world, various states pay special attention to their cultural diplomacy and the formation of their image. The purpose of cultural diplomacy is to strengthen international relations with foreign countries and influence on the system of international relations. It also plays an important role in shaping the image and improving status in the world community. The cultural factor, as a “soft power” in international politics, seriously affects the socio-economic processes in the world and international relations. The term "soft power" refers to cultural diplomacy conducted by a particular state. Japan, which is one of the developed countries of the world, pays special attention to the soft power factor in foreign policy. It is known that Japan managed to preserve the values of its national culture, despite the fact that it used the achievements of Western civilization for many decades. And therefore, modern Japanese culture is characterized by the fact that it harmoniously combines tradition and modernity. Thanks to the successful combination of national characteristics and the achievements of computer digital technologies, Japan has become a world leader among information societies. Cultural diplomacy not only serves Japan to resolve many issues of a political and economic nature, but also integrates it deeper into the international community and enhances its image in the international arena. Thus, Japan, effectively using the processes of globalization, has achieved world recognition of its culture through the development of cultural diplomacy. In this regard, it is of interest to us to study the best practices of Japan in this area.
In Uzbek poetry of the independence period, which is a legitimate part of world literature, special attention is paid to the generalization of scientific theoretical views on the creative worldview and creative philosophy of the socio historical period, the artistic perception of reality in poetry and the study of artistic realization. The intensification of the desire for the deep artistic development of the human spiritual world in the poetry of the independence period is associated with the renewal of the period, the historical environment and the artistic thinking of the creators themselves. The harmony of poetry and literary-aesthetic views is a direct result of the synthesis of the principles of creative phenomenon, personality, perception of the world, which is reflected in the author's "I". Image poetics plays an important role in revealing the creative concept and uniting it into a common denominator. The perfection of the product of artistic thinking as a synthesized system is determined by the level of creative thinking and talent. The work of Amir Khudoiberdi is one of such events in the history of national artistic thought, and in the works of the poet created in different genres, he expresses the life, dreams and will of the people in different socio-historical periods. The poet's tendency to create a holistic artistic history of the Uzbek people in the twentieth century is explained by the vast opportunities provided by independence, the end of ideological monopoly, the restoration of national values, the renewal of literary and aesthetic views, the translation of world literature into Uzbek. The transition from the depiction of things to the depiction of ideas has changed the content of artistic creation, while enriching the formal, semantic scale of artistic research.
Close acquaintance with world poetry has long served as one of the important factors in the renewal of our national literature, separated from its spiritual sources- religious and mystical literature, classical and modern literature. The content of the themes of emotional literature is characterized by a focus on the person, not directly on reality. The synthesis of world literary traditions can be seen in the works of Fakhriyor, Ulugbek Hamdam, Bahrom Ruzimuhammad, Farida Afroz, Nodira Afokova, Zebo Mirzaeva, Khosiyat Rustamova, Gozal Begim. Amir Khudoiberdi is also one of the poets of this literary generation who has his own creative credo and works in various genres. Any national literature manifests itself as a systematic, evolving stable phenomenon only in the harmony of different ideologies, styles, views, approaches, ideas, and even contradictions. Only then can it be a true metaphorical representation of being. Amir Khudoiberdi is one of the new generation of artists who lived in a complex and controversial period and saw and understood the subjective approaches to the literature of the Soviet era. A comprehensive scientific study of the creative style, individuality and mastery in the poetry of the independence period on the example of the work of a poet, the generalization of scientific and theoretical views on the poetry of this period gives important conclusions, this scientific research is the product of such a necessary need. In Uzbek literature, the works of Amir Khudoiberdi have not yet been comprehensively studied. The study of the poet’s work is also important in determining the influence, position, and place of local artists in literature. Also, the issue of art and literature, which is one of the means of spiritual and educational environment, education and their formation in our country, has always been in the forefront. Therefore, as the President of Uzbekistan Sh.M.Mirziyoev said: “...attention to literature and art, culture is first of all attention to our people, attention to our future, as our great poet Cholpon said, we have no right to forget that literature, culture and nation can live ”. This fact also determines the relevance of the topic.
Accordingly, this study is based on the Decree of the President of the Republic of Uzbekistan dated February 7, 2017 No. PF-4947 "On the Strategy for further development of the Republic of Uzbekistan", dated September 13, 2017 No. PQ- 3271 "Development of the system of publishing and distribution of books. to a certain extent in the implementation of the tasks set out in the Resolution "On a comprehensive program of measures to improve and promote the culture of reading and reading" and other regulations related to this activity.
The Cold War was not only traditional in international relations next phase of the struggle for world domination, but also an ideological war aimed to impose on the opposing powers a certain value system, social structure, political regime, etc. As a result the ideological conflict of the opposing powers became an important component of the Cold War. With the end of the Cold War the problems of «end of history» and the “end of ideologies” were actualized on the West. It became about an axiom that the world politics lost its ideological dimension. In fact, however, ideological component is deeply integrated into the emerging «new» world order. Even the dominance of Western countries in the emerging system of international relations was legitimated by the postulates of neo-liberalism. The coming to power in the USA of president D. Trump and changes in American foreign policy stress a deep transformation in the modern system of international 51 relations. Unconditional dominance of the liberal paradigm in global scale is gradually coming to an end. This process is accelerated due to the completion of the «unipolar moment» in world politics and process of step by step formation of a polycentric world order. The world is entering to a turbulent era. And one of its main features will probably be decline of ideology influence and the strengthening of political realism as an intellectual dominant in making decisions in dynamic and unclear international environment.
This scientific article expounds analytical thoughts that in the first decades of the twenty-first century the level of global problems related to the security of mankind has increased many times over, the reasons for this phenomenon are also stated, including the inconsistency of the formation of a new world order, the difficulties of democratization. Conclusions are drawn about new false barriers to the formation of new international relations. The article focuses on the significance of the 75th anniversary session of the General Assembly of the United Nations and new conceptual ideas that were voiced in the speech of the President of the Republic of Uzbekistan Sh.Mirziyoyev. The author concludes that the constructive ideas and initiatives put forward in the speech of the President of our country will be of great importance in the formation of a fair international system, and at the same time, the institutional capacities and effectiveness of the UN will increase. The article concludes that as a result of the implementation of the new ideas put forward, the recommendations of the head of our state under the auspices of the UN, a very large number of problems facing humanity will find their positive solution, as a result, new conditions will appear for the formation of a modern, fair, democratic world order. The article emphasizes that the new ideas put forward by the President of our country, in their essence, are aimed at updating the world order. In this regard, our President calls for an increase in common responsibility, as well as strengthening the democratic approaches of the world community to address these challenges. Therefore, the author believes that the initiatives of our head of state have a very positive meaning for all peoples of the world. The scientific article emphasizes that the proposal of the head of the country to increase the role of national parliaments is also of historical importance. In this regard, as noted in the article, the initiative of the President of the Republic of Uzbekistan for the adoption by the UN of a special decision to enhance the role of parliaments is extremely important for the formation of modern foundations for the development of parliamentary diplomacy. Also, the article pays special attention to the historical role and significance of the new initiatives of the President of the Republic of Uzbekistan for the peaceful solution of the problem of Afghanistan. The article concludes that these fundamentally new, effective initiatives to solve the Afghan problem will contribute to a thorough solution to all the contradictions that exist in modern Afghanistan.
The article deals with the study of the picture of the world and its language expression. This issue is the subject of close attention of many disciplines.
This article deals with the experience of translating historical novels in translation studies. It is also devoted to current and important problems of the theory and practice of translation of historical novels in translation studies today. The process of translating historical novels in translation studies is explained on the basis of examples of educational, political, ideological and aesthetic significance. It says that the translation of historical novels into foreign languages is important in promoting the national values of the
people to the world. The article also discusses the role of the experience of world translation schools in the translation of historical novels in translation studies, as well as a comparative analysis of the specific methods of the Uzbek National School of translation studies and world translation schools. It is emphasized that the translation of historical novels, unlike works of other genres, is important as works of high artistic expression, which clearly show the history, values, spiritual world and national spirit of the people. The main condition for achieving adequacy in the translation of historical novels is the transfer of artistic originality of the original, its national characteristics and the ability to fully reflect the individual creative style of the author. It also considers the successes and shortcomings of direct or indirect translation from one language to another. Of course, in the direct translations of historical novels, special attention is paid to the fact that the mastery of the translator is the primary task in restoring the artistry of the work. Also, the genesis of translation of Uzbek historical
novels, methods of translation, especially the problem of style in translation into English and
the peculiarities of working on the translation of historical works are studied on a scientific
basis. In this regard, scientific and practical recommendations have been given today, taking
into account the experimental trends of the world schools of translation, to improve the mechanisms of action for the formation of professional competence in the practice of translating historical novels.
Malignancies have been increasingly regarded as one of the main challenges to healthcare systems throughout the world. Malignant diseases were reported by the World Health Organization to be the second leading cause of death throughout the world accounting for about sixth of all deaths during the year 2018. There has been increasing interest in the historic patterns of malignant disease which can help in establishing understanding of the possible changes of pattern of cancer. The aim of this paper is to provide an overview of the pattern of malignancy in Iraq during the previous half century.
The top five cancers reported in Iraq during ten-year period (1976-1985) were different from the top cancers throughout the world as reported by the World Health Organization during the previous years. The pattern of malignant disease in Iraq during the years 2000 to 2004 was rather different from the pattern of malignancies in other countries like United States of America. The incidence rate of new cases of malignancies were increasing during the previous decades as it was 38.91/100,000 population in 1994, 52.8\100,000 in 2006, and 82.62/100,000 population in 2018. The pattern of cancers in Iraq was not very similar to the latest global pattern reported by the World Health Organization. In addition, the pattern of childhood cancers in Iraq witnessed some changes during the previous decades.
This article analyzes the linguistic and pragmatic features of a journalistic text. It is known that in the mass process of modern communicative society, publicistic communication takes an increasingly important place. A single center of knowledge and periphery comes to replace a multifaceted world with diverse knowledge and culture. This center has its own industries, which it provides with the necessary knowledge. The characterization of the modern communication society by such a clash will radically change our life. These changes will manifest themselves through the formation of public opinion. Scientific research carried out in the fields of linguistics and journalism in recent years is devoted to the problems of society, culture and other issues. It is generally accepted that factors such as economics, politics, cultural and national customs and traditions have a direct impact on the language. It is impossible to deny the fact that this list of sociocultural criteria needs to be clarified and supplemented. Therefore, the consideration of the specific communicative speech activity of journalism in a pragmatic aspect requires a modern approach.
In modern abdominal surgery, one of the current areas for research continues to be the improvement of various options for plastic surgery of postoperative hernias. More than 2,100,000 operations for ventral hernia are performed annually in the world, and 42% of them are postoperative hernias. In recent years, there has been a clear trend toward the expanded use of various types of biological meshes in hernioplasty. “A pooled analysis of seven PCSTAR studies for incisional hernias using retromuscular mesh showed a hernia recurrence rate of 5.7%”[1]. The use of standard surgical interventions such as alloplasty in the onlay position does not solve the problem of early postoperative complications: seroma discharge, mesh migration, adhesive disease, high frequency of hernia recurrence, etc. At the same time, hernia repair with local tissue creates the problem of increased intra-abdominal pressure and late complications in the form of recurrent hernias. “An increase in postoperative intra-abdominal pressure leads to multiple organ failure, then abdominal compartment syndrome, and even death.” [2]. Currently, there is no consensus on the surgical approach for giant postoperative abdominal wall hernias, and therefore the need to continue to develop new technologies and improve There is no doubt about the tactics. In world practice, at present, the most relevant studies continue to be studies aimed at studying the morphological and functional aspects of recurrent postoperative ventral hernias; electron microscopy reveals ultrastructural destructive changes in skin cells, aponeurosis and muscles, which indicates morphofunctional insufficiency of abdominal wall tissues; issues of cell engineering are discussed new innovative materials, experimental studies are being carried out on animals testing the biotechnical properties, texture and elasticity of new polymers, research is being conducted on open approaches with division of the posterior component with the release of the transverse abdominis muscle and a retrograde mesh, robotic operations have begun. Modern aspects of the development of domestic healthcare include many measures aimed at improving the results of treatment of patients with postoperative ventral hernias and associated pathological conditions through the introduction of modern principles of intensive care and surgical tactics. The development strategy of New Uzbekistan for 2022-2026 in seven priority areas includes tasks to improve the quality of provision of qualified medical services to the population[3]. The implementation of these tasks, including by optimizing tactical and technical approaches to the choice of hernioplasty method, as well as the development of methods for the prevention of purulent-inflammatory complications in the field of alloplastic material, is one of the current areas of abdominal surgery and medicine in general, due to the high medical and social the significance of this pathology.
This dissertation research to a certain extent serves to fulfill the tasks approved by the Decree of the President of the Republic of Uzbekistan “On comprehensive measures to radically improve the healthcare system of the Republic of Uzbekistan” No. UP-5590 dated December 17, 2018, the Resolutions of the President of the Republic of Uzbekistan “On measures to transform the surgical service, improving the quality and expanding the scale of surgical operations in the regions" for No. PP-5254 dated October 4, 2021 and "On additional measures to ensure public health by further increasing the efficiency of medical prevention work" for No. PP-4891 dated November 12, 2020, and as well as other regulatory documents adopted in this area. Compliance of the research with the priority directions of development of science and technology of the republic. The dissertation research was carried out in accordance with the priority direction of development of science and technology of the VI Republic “Medicine and Pharmacology”. Review of foreign scientific research on the topic of the dissertation.[4] Research work aimed at improving the quality of therapeutic and preventive care for patients with ventral hernias, carried out by many leading scientific centers and higher educational institutions in the world, including the Department of Surgical and Perioperative Sciences, Umeå University, Umeå (Sweden), Department of Surgery, Kingston General Hospital, 76 Stuart Street, Kingston (Sweden). nada), Department of Surgery, Helsinki University Hospital, Helsinki ( Finland), Service de chirurgie digestive et oncologique, CHU d'Amiens (France), Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Tulsa (USA), Department of Surgery, Howard University College of Medicine, Washington (USA) , Yong Loo Lin School of Medicine, National University of Singapore (Singapore), Department of Surgery, Michigan Medicine, Ann Arbor, MI, USA; University of Calgary, Calgary (Canada), Division of Plastic Surgery, Perelman School of Medicine at the University of Pennsylvania, University of Pennsylvania Health System, Philadelphia (USA), Brigham and Women's/Faulkner Hospital, Harvard Medical School, Boston (USA) , Department of Surgical Sciences, Uppsala University Hospital, Uppsala (Sweden), Department of Surgery, University of Texas Health Sciences Center at Houston, Houston (USA), Department of Surgery, Erasmus University Medical Center Rotterdam, Rotterdam (Netherlands), Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University, Fukuoka (Japan), National Medical Research Center for Surgery named after A.V. Vishnevsky" (Russia), Republican Scientific Center for Emergency Medical Care (Uzbekistan), Tashkent Medical Academy (Uzbekistan), Republican Specialized Scientific and Practical Medical Center for Surgery named after Academician V. Vakhidov (Uzbekistan).
As a result of studies conducted around the world to increase the effectiveness of alloplasty for postoperative ventral hernias and reduce the risk of complications in the postoperative period, a number of scientific results were obtained, including: it was determined that patients who underwent reconstruction of the abdominal wall have an increased risk of postoperative respiratory failure, understanding the epidemiology of this complication can improve prevention (the Division of Plastic and Reconstructive Surgery, Department of Surgery, Oregon Health & Science University, USA); It has been proven that the larger the hernia, the higher the risk of early surgical complications, including such as respiratory decompensation, since hernias often increase in size over time, delaying surgery can lead to an increase in the size of the hernia and, therefore, a greater risk of complications (CentreforDigestiveDiseases, KarolinskaUniversityHospital, Stockholm, Sweden); it has been shown that the ratio of the hernia volume to the volume of the abdominal cavity <20% is an independent factor in tension-free closure, which justifies the interest in preoperative volumetry to adapt the tactics of surgical care (Servicedechirurgiegénérale, digestiveetendocrinienne, CHU LyonSud, HospicescivilsdeLyon, France); It has been determined that in patients undergoing elective laparoscopic hernia repair, predictors of mortality are older age and certain concomitant diseases: congestive heart failure, pulmonary circulatory disorders, coagulopathy, liver disease, metastatic cancer, neurological disorders and paralysis (Department of Surgery, College of Medicine, University of Oklahoma, Tulsa , USA); Older age, ascites, preoperative renal and pulmonary insufficiency have been found to be independent predictors of 30-day mortality, and in the presence of these risk factors, conservative treatment should be seriously considered (Department of Surgery, University of Kentucky College of Medicine, Lexington, USA); The American College of Surgeons (ACS) Universal Surgical Risk Calculator has been shown to accurately predict thirty-day outcomes, including major complications: venous thromboembolism, medical morbidity, surgical site infection, unplanned reoperation, mortality, and length of hospital stay (Department of Plastic Surgery, Brown University and Rhode Island Hospital, Providence, USA). At the present time in the world, the most relevant research in surgery continues to be the development of new methods of hernioplasty for large and giant ventral hernias, each of which has its own pros and cons depending on the complexity of implementation, the risk of postoperative complications and relapse, large randomized clinical trials are being conducted, comparing existing methods of traditional hernioplasty with laparoscopic access and robotic surgery, which has become increasingly widespread in the last 10 years, a search is being made for new synthetic and biological materials developed for the production and use of composite meshes that have the necessary strength and the ability to prevent fatal local complications in a contaminated environment. However, despite technical advances in this field, no modern hernia repair method or prosthesis meets all the requirements. One of the key problems is that existing synthetic endoprostheses do not have sufficient elasticity, resistance to infection, high mechanical strength and integrity over a long period of time. Further research into these clinical aspects will undoubtedly improve the current understanding of the capabilities of biocompatible endoprostheses and will make it possible to develop an optimal method for their placement during allohernioplasty. The degree of knowledge of the problem. The current period of development of abdominal surgery is characterized by an emphasis on the problems of the effectiveness of introducing new installation methods and techniques for attaching bioprostheses, options for various suture materials to determine the most promising directions for the development of these technologies [5]. Researchers led by BittnerR.[6] (2019) state that a giant postoperative abdominal wall hernia, the maximum diameter of which exceeds 12 cm or the ratio of the volume of the hernial sac to the abdominal cavity more than 20%, is difficult to treat, with a high recurrence rate and a large number of complications. One of the most challenging problems is that after the hernia contents return to the abdominal cavity, postoperative intra-abdominal pressure will increase, leading to multiple organ failure, then abdominal compartment syndrome (ACS), and even death. There is currently no agreement on the surgical approach for these giant incisional abdominal wall hernias. To prevent recurrences, some articles recommend placing the hernia mesh in the sublayer position and or linings (KirkpatrickAW.)[7]. According to CornetteB.[8], to prevent recurrence, it is recommended to place the hernia mesh in a sublayer or underlay position, and to achieve better mesh expansion, a component separation technique (CST) may be a suitable solution, but with a significant risk of complications and recurrence. JensenKK, et al. believe that truly successful giant hernia repair requires effective bridging or augmentation that will prevent recurrence with an acceptable risk of complications[9]. Another pressing issue in abdominal surgery is that patients with incisional hernias are extremely difficult to treat due to a number of factors including obesity, previous hernia repair, previous mesh placement, domain loss, and other variables.
The approach to patients with incisional hernias has changed significantly over the past 20 years due to both advances in mesh technology and surgical approaches. Key factors for successful outcome include modification of risk factors preoperatively, such as smoking cessation and weight loss, selection of mesh appropriate for the type of hernia and planned mesh location, and wide mesh coverage beyond the hernia defect. New techniques such as transabdominal muscle release and component separation with retrograde mesh placement and robotic approaches to abdominal wall hernia are increasingly being used in these patients[10]. Recent years have seen an increase in the number of biological meshes available for abdominal wall hernia repair. Biological meshes typically consist of materials obtained from humans, pigs, or cattle. The rationale for using biological meshes is that they can act as a scaffold for the growth of natural tissues. In addition, there are absorbable synthetic meshes that have properties similar to those of biological meshes, but with theoretically less risk because they are not derived from animal or human material. The choice of mesh for a ventral hernia depends on many factors, which include both the properties of the mesh and its location, for example, whether it should be placed intraperitoneally, preperitoneally, or retrorectus. BaierKF[11](2021) believes that the guiding principle should be to avoid placing uncoated polypropylene mesh in an intraperitoneal location where it may be in direct contact with internal organs. In addition, the type of hernia defect is another risk factor, such as whether the wound is clean or dirty, and whether the repair is performed with a bridge or abutment. Lightweight or biologic meshes to bridge the defect should be avoided due to increased recurrence rates. Holihan JL [12] (2016), Hodgkinson JD [13] (2018) believe that the principle of anatomical restoration to achieve a reliable, tension-free repair with reinforced mesh reduces the incidence of early postoperative complications and late recurrence of hernia compared with bridging mesh. The analysis of the literature concerning the theoretical aspects and clinical experience of using technologies for improving modern synthetic and biological prostheses that can provide a better plastic effect, as well as methods for preventing recurrence of ventral hernias, indicates that this is one of the priority areas in modern abdominal surgery. An unresolved issue remains the choice of the optimal endoprosthesis, which is highly effective and meets international standards for such properties as biological inertness and mechanical strength, as well as the method of positioning the mesh in relation to the layers of the abdominal wall. Considering that many of the allohernioplasty methods used today are not without drawbacks, the current direction is the development of new methods of repair for giant ventral hernias and methods for the prevention of postoperative complications in conditions of a contaminated wound, with justification of their effectiveness in a clinical experimental study. The connection between the dissertation research and the research plans of the research institution where the dissertation was completed. The dissertation research was carried out within the framework of the research work plan of the State Institution “RSNPMCH named after. acad. V. Vakhidov" under the project AL-422105574 "Development of new biocompatible mesh implants made of composite materials for reconstructive surgery of abdominal and diaphragmatic hernias" (2022-2024).
The purpose of the study is to improve the results of surgical treatment of large and giant postoperative ventral hernias by introducing new laser technologies and improving the tactical and technical aspects of surgical treatment. Objectives of the study: to study the structure of immediate complications after various types of prosthetic plastic surgery; to clarify the influence of obesity factors, primary or repeat hernioplasty on the incidence of immediate and long-term complications; to evaluate the role of the immediate complicated course of the postoperative period in the incidence of long-term complications of hernioplasty; to improve the technical aspects of alloplasty for large and giant postoperative ventral hernias (POVH); to improve the technique of photodynamic therapy (PDT) of the wound surface after prosthetic plastic surgery; to study in an experiment the effectiveness of using the proposed technique of alloplasty and PDT; evaluate the morphological features of the condition of tissues during prosthetic plastic surgery using the proposed method; in a comparative aspect, evaluate the clinical effectiveness of the proposed alloplasty options in the immediate and long-term periods. The object of the study was the results of allohernioplasty in 448 patients with extensive (large) and giant POVH, who were operated on at the surgical department of the 1st clinic of the Samarkand State Medical Institute in the period from 2012 to 2021, as well as experimental animals on which the effectiveness was assessed developed a technique for prosthetic repair of postoperative ventral hernias and applied the technique of photodynamic therapy.
The subject of the study is to analyze the effectiveness of the developed alloplasty of postoperative ventral hernias and intraoperative photodynamic therapy in abdominal surgery in experiments and in the clinic. Research methods. To achieve the goal of the study and solve the assigned problems, general clinical, instrumental, biotechnological, experimental, histomorphological, microbiological and statistical research methods were used. The scientific novelty of the study is as follows: it was established that the need for extensive tissue mobilization and, as a consequence, the intersection of lymphatic capillaries during implantation of the prosthesis in the onlay position, as well as the lack of sufficient resorption function of the hernial sac in the inlay position causes a high risk of the formation of clinically significant seromas; It was determined that with prosthetic hernioplasty, along with the volume of the defect, the type of plastic surgery and the degree of obesity, the most significant predictor of the risk of developing immediate complications is the factor of re-intervention in case of recurrent hernia with the presence of a “dormant infection” hidden in the remaining ligature granulomas or scar tissue; the structure and clinical features of the course of long-term complications of hernioplasty for giant and extensive hernias were clarified, taking into account the results of the immediate postoperative period, as well as the option of fixing the prosthesis, primary or repeated hernioplasty and the degree of obesity; the method of surgery for large hernias of the anterior abdominal wall has been improved, characterized by a combination of factors such as the formation of tension-free prosthetic repair, preservation of local resorptive function to prevent the development of fluid accumulations and reducing the risk of infection; the method of preventing the development or progression of wound infection during alloplasty of ventral hernias has been improved, aimed at enhancing the antibacterial effect and stimulating reparative activity through the photosensitizing and photodynamic effect of low-energy laser radiation; It was determined in an experimental model of prosthetic plastic surgery that the proposed method of fixing the prosthesis in combination with the use of the effect of photodynamic therapy through laser radiation helps to enhance reparative processes with a reduced risk of wound complications; It has been proven that all methods of antiseptic exposure and laser stimulation of the wound surface after prosthetic plastic surgery enhance preventive measures against the development of local infection, but are ineffective in the case of an already developed purulent-inflammatory process against the background of the use of alloplastic material. The practical results of the study are as follows: it has been determined that the implantation of synthetic materials for giant and extensive hernias is accompanied by a significant number of wound complications caused by both the surgical technique itself and the reaction of surrounding tissues to a foreign body, requiring improvement of tactical and technical approaches when performing hernioplasty; it was clarified that scar-degenerative changes in the tissues of the aponeurosis in giant and extensive hernias are a predisposing factor to the occurrence of post-prosthetic hernias, especially when implanting the prosthesis in the “inlay” position and, accordingly, require increasing the efficiency of their fixation and engraftment, as well as reducing the risk of developing local complications; it was determined based on the data of an experimental study that the proposed method of alloplasty for large ventral hernias makes it possible to achieve adequate reconstruction of the anterior abdominal wall, reduce the incidence of infection in the wound, and also use a smaller size of prosthetic material; it was determined that the proposed method of tension-free repair of large hernias of the anterior abdominal wall with strengthening of the aponeurosis with a mesh implant allows maintaining physiology, reducing the number of complications, shortening treatment time and reducing the risk of hernia recurrence; It has been determined that the proposed method for preventing the development or progression of wound infection during alloplasty of ventral hernias can reduce the frequency of suppuration, shorten the treatment time and the likelihood of relapse; It has been proven that the use of the proposed tactical and technical aspects of prosthetic repair for postoperative ventral hernias can reduce the incidence of specific complications, reduce rehabilitation time and the risk of hernia recurrence. Reliability of the research results. The reliability of the results is justified by the use of objective criteria for assessing the condition of patients, modern methods of diagnosis and treatment, the correct application of methodological approaches and sets of statistical analysis, methods for solving the problems discussed in the dissertation are based on modern scientific and practical concepts and approaches to the diagnosis and surgical treatment of patients with giant postoperative hernias. Scientific and practical significance of the research results. The results obtained make a significant contribution to the expansion of irradiation of existing ideas about the structure and clinical features of complications of hernioplasty for giant and extensive ventral hernias by identifying the morphological features of the development of a purulent-inflammatory process against the background of the use of alloplastic material, studying predictors of the risk of developing immediate complications, mechanisms for enhancing reparative processes through the use of an improved method of fixing the prosthesis in together using the effect of photodynamic therapy through laser radiation, which made it possible to enhance the antibacterial effect and improve the wound healing process. The practical significance of the study is that, based on the results obtained, the tactical and technical aspects of prosthetic hernioplasty have been optimized, the features of methods of antiseptic exposure and laser stimulation of the wound surface after prosthetic repair have been revealed, enhancing preventive measures for the development of local infection, and the method of surgery for large anterior abdominal hernias has been improved walls, characterized by a combination of factors such as the formation of tension-free prosthetic plasty, preservation of local resorptive function to prevent the development of fluid accumulations, thereby reducing the risk of developing postoperative complications, reducing the frequency of unsatisfactory results, length of hospitalization and the likelihood of relapse. Implementation of research results. According to the results of a scientific study to optimize the tactical and technical aspects of surgical treatment of large and giant postoperative ventral hernias: the “method for plastic surgery of giant hernias of the anterior abdominal wall” has been improved (invention patent No. IAP 2022 0148 dated April 18, 2022). The proposed method of tension-free repair of large hernias of the anterior abdominal wall with strengthening of the aponeurosis with a mesh implant made it possible to reduce the number of complications, shorten the treatment time and reduce the risk of hernia recurrence; the “method for preventing the progression of infection during alloplasty of infected hernias” has been improved (certificate of the Ministry of Health No. 08-32071 dated October 17, 2022). The proposed method made it possible to reduce the frequency of wound purulent-inflammatory complications and shorten the period of rehabilitation of patients after allohernioplasty; methodological recommendations “Tactical and technical aspects of prosthetic repair for large and giant postoperative ventral hernias” have been developed (certificate of the Ministry of Health No. 08-32071 dated October 17, 2022) . The developed recommendations made it possible to optimize the tactical and technical aspects of allohernioplasty in patients with large and giant postoperative ventral hernias; The scientific results obtained were introduced into the practical activities of healthcare, in particular, in the departments of surgery of the Khorezm and Andijan regional multidisciplinary medical centers, the clinic of the Samarkand State Medical University (certificate of the Ministry of Health No. 08-32071 dated October 17, 2022). Improving the tactical and technical aspects of prosthetic repair for postoperative ventral hernias has made it possible to reduce the incidence of specific immediate complications from 40.9% to 15.6%, to reduce rehabilitation time from 8.6±2.7 to 7.1±1.5 days, and also reduce the likelihood of long-term complications from 11.7% to 3.1%. Approbation of research results. The results of this study were discussed at 8 scientific and practical conferences, including 5 international and 3 republican ones. Publication of research results. 26 scientific works have been published on the topic of the dissertation, including 9 journal articles, 4 of which in republican and 5 in foreign journals recommended by the Higher Attestation Commission of the Republic of Uzbekistan for publication of the main scientific results of doctoral dissertations. Structure and scope of the dissertation. The dissertation consists of an introduction, seven chapters, a conclusion, conclusions, practical recommendations and a list of cited literature. The volume of work is 200 pages.
A person is in contact with the outside world throughout his life and receives information about it and from it with the help of five senses. According to M. McLuhan, one of the famous sociologists of the 20th century, a person perceives reality not as it is, but as "given" by means of communication. Today's world is a visually oriented world, a world of virtual opportunities and information technology. Therefore, television and video began to attract viewers not only as entertainment, but also actively used for educational purposes in all areas of human activity, including education.
Over the past few decades, Islamic finance has developed in very fast pace accupying big place in the world economy and the value of its assets is increasing rapidly day by day. This article aims to give brief information about what exactly Islamic finance is, investigate its role in the world economy and why it should be introduced to Uzbekistan. Comparative, event analysis, content analysis methods were used while writing this article. The benefits of Islamic finance for Uzbekistan, the develoments which will come after introducing it were concluded in this scientific work. This academic writing may be useful for economists and officials in making contribution to the development of Uzbekistan economy.
There are different opinions about the origin of the “Thousand and One Nights”, one of the masterpieces and pearls of world civilization, and science it was translated into different languages of the world. Scientists of the world expressed opinions on this issue, and the author in the article cites his views on these conclusions. Scientists are divided into two camps in their views on the origin of the source. On the first side were scholars who believed that the source of all fairy tales in the collection is Arabic folklore. We admite true who thinks that this work of Persian folklore. The omnibus was writed in pehlavi language and was very famous in Iranian language. This folklore product was translated from pehlavi into Arabian language e in golden age of Arabian translation, actually in 9-10 centuries. The names of heroes “Thousand and One Nights” Padishah Shakhriyor and Princesse Shakhrezad are persian. The book “Alf Leila wa Leila” belongs and tells not only about the Arabs, but also when creating the work, the motifs of fairy tales from Central Asia, Iran and India were used. Analyzed on the example of a combination of motifs and plots of world folklore of different peoples and the processes of “plot migration”. There two options for this source. The first option is the translation of Persians into Arabic in the 8 th century. The second version was assembled in the 10 th century by Jahshiyor, who came from Baghdad. Explain of oral creation is recognized Egyptian fary tales, were collected by Jaxshiyor, was written in 13-14 centuries. The famous omnibus which named “Thousand fary tales” was collected in Egypt after that the new fary tales were added. “A Thousand and One Nights” was originally created in the form of Indian fairy tales cultivated by Arab masters, and became a unique monument of the Arab people. The current copy of the collection is a valuable monument of the Arab people. It is also a unique gem of world civilization. Literatury antiques of all Orient nation and uzbek are recognized antiques like on “Thousand and One Nights”.