602
Ann. For. Res. 65(1): 602-607, 2022
DOI: 10.5281/zenodo.7213307
ANNALS OF FOREST RESEARCH
https://www.e-afr.org/
© ICAS 2022
EPIZOOTOLOGY OF EIMERIOSIS (COCCIDIOSIS) OF RABBITS, TREATMENT
AND PREVENTIVE MEASURES.
Davlatov Ravshan Berdiyevich
Professor,
Khushnazarov Alisher Khudoiyberdi o‘g‘li
PhD student,
Khushnazarova Mohigul Ilhomovna
student, Samarkand State University Of Veterinary Medicine, Livestock And Biotechnologies.
Annotation:
This article presents scientific data on the effectiveness of drugs that are currently
used in the treatment of eimeria in rabbits, which have been demonstrated in experiments with
antiparasitic and anti-inflammatory effects on the tissues of spontaneously infected rabbits. And
the results of scientific research on epizootology, diagnostics and measures to counteract rabbits
contained in our republic.
Keywords:
Rabbit, eimeriosis, oocyst, invasion, parasitological method, coprological method,
extensiveness, intensity, eimeriostatic, intracox oral, furazolidone.
Introduction.
In recent years, in our country, special attention has been paid to the development
of animal husbandry, in particular rabbit breeding, which is one of the small branches of animal
husbandry. To do this, special programs are being developed and a number of facilities for industry
representatives are being created. One of the important steps in this direction was the state
registration of the Association of Rabbit Breeders of Uzbekistan by the Ministry of Justice of the
Republic of Uzbekistan on December 12, 2018 No. 859.
Taking into account the current trends in healthy eating and the recommendations of the World
Health Organization on the norm of dietary consumption of meat, it should be noted that 5% of
meat is consumed per year, that is, 4.5 kg of rabbit meat. Based on this, we can say that in the
markets of our country there is a demand for 150,000 tons of rabbit meat per year.
Relevance of the topic.
Currently, rabbit breeding in the country is at an early stage of
development, and there are not many people involved in this profitable business. They also lack
knowledge and skills. Therefore, it is important to intensify educational work in this area, develop
rabbit breeding at an industrial level and form the fodder base of the industry.
When performing these urgent tasks, there is a risk of certain parasitic diseases in rabbits, and the
introduction of effective methods of their prevention and treatment into production is a necessity
for this industry. Because parasitic diseases of rabbits in our country are practically not studied by
researchers.
603
Ann. For. Res. 65(1): 602-607, 2022
DOI: 10.5281/zenodo.7213307
ANNALS OF FOREST RESEARCH
https://www.e-afr.org/
© ICAS 2022
The amount of protein in rabbit meat is higher than in lamb, beef and pork. By the content of
vitamins and minerals, it surpasses almost all types of meat. The content of vitamins, macro- and
microelements in rabbit meat cannot be compared with any other type of animal meat (table 1).
Table 1
The chemical composition of rabbit meat
Body parts
Percentage of div weight (%)
Energy value of 100
g of meat, kcal.
Water
Protein
Fat
Ash
Thigh – shin
70,30
21,21
5,83
2,66
140,31
Shoulder blade –
shoulder
71,39
20,43
4,87
3,31
122,05
Waist – coccyx
71,05
19,96
6,98
2,01
147,14
Neck-chest
71,95
18,76
5,42
3,87
124,82
long fibrous muscle
71,03
22,10
4,10
2,77
125,53
Purpose and objectives of the study.
The main purpose of the study is to determinate and analyze
the epizootology of eimeriosis (coccidiosis) in rabbits, and to develop therapeutic and preventive
measures.
Our research was conducted in the Pastdargom and Urgut districts of the Samarkand region.
Experimental, microscopic, parasitological, scatological and statistical methods were used during
the research.
Research results.
Initially, the presence of eimerium oocyst was determined in the faecal samples
of the examined rabbits, and then the study was continued.
As a result of the study and analysis of the epizootology of eimeriosis (coccidiosis) of rabbits, it
was found that 70 out of 155 rabbits grown at the State Unitary Enterprise "Guzalkent Dostoni"
are infected with eimeriosis, the prevalence of invasion was 45.1%, out of 225 rabbits bred at the
private enterprise "Maxudabonu business service" of the Urgut district, 80 were diagnosed with
eimeriosis, the extensive invasion was 35.5% (Table 2).
Table 2
The results of a coprological study of eimeriosis in rabbits
Name of the farm
Number of
rabbits
Check method
Extensiveness of
invasion
number
percent
SUE "Guzalkent
Dostoni"
155
coprological
70
45,1
PE "Maxsudabonu
business service"
225
coprological
80
35,5
604
Ann. For. Res. 65(1): 602-607, 2022
DOI: 10.5281/zenodo.7213307
ANNALS OF FOREST RESEARCH
https://www.e-afr.org/
© ICAS 2022
Thus, the prevalence of invasion in both farms averaged 40.3%.
Antiparasitic drugs effective against eimeriosis have been tested for the treatment and prevention
of eimeriosis in rabbits.
For comparison, we studied the eimeriostatic effects of
“Intracox oral”
(Interchemie werken “De
Adelaar” B.V.Metaalveg Nederland) and the eimeriostatic effects of
furazolidone
.
For the experiment, rabbits with a spontaneous disease of eimeriosis and a high intensity of
invasion were selected, which were divided into 4 groups according to the rule of analogues: 1 -
healthy control group; 2 patients in the control group; 3-4 were divided into experimental groups
(Table 3).
Table 3
Results of coprological research of rabbits
Groups
Experience
control
Number of
rabbits
Check method
Microscopy results
1 Group
Healthy
65
Coprological
Negative
2 Group
Patient Control
Group
65
Coprological
Positive
3 Group
Experience
65
Coprological
Positive
4 Group
Experience
65
Coprological
Positive
In the course of examinations after clinical, parasitological, microscopic examination of all four
groups of rabbits, the following eimeriostatic preparations were tested on rabbits of groups 3-4,
where experiments were carried out to detect eimeriosis.
Rabbits of the 3rd group were injected with the drug
"Intracox oral"
, dissolved in 1 ml per 1000
ml of water, continuously for 2 days;
Rabbits of the 4th group were given 0.5 g of
furazolidone
per 1 kg of feed for 9 days.
Rabbits of the control groups 1-2 were not given the drug.
The effectiveness of the drugs used was determined based on the clinical signs of the disease and
the results of laboratory tests (table 4).
605
Ann. For. Res. 65(1): 602-607, 2022
DOI: 10.5281/zenodo.7213307
ANNALS OF FOREST RESEARCH
https://www.e-afr.org/
© ICAS 2022
Table 4
The results of the effectiveness of drugs used in the treatment of rabbit eimeriosis
№
G
ro
u
p
s
Name of the
Groups
N
am
e
of
d
ru
gs
D
os
e
of
d
ru
gs
N
u
m
b
er
o
f
ra
b
b
it
s
in
a
g
ro
u
p
T
h
e
sa
fe
ty
o
f
ra
b
b
it
s
in
t
h
e
gr
ou
p
,%
Intensity of invasion after drug
administration
T
h
e
ef
fe
ct
iv
en
es
s
of
t
h
e
d
ru
g,
%
Examination dates (number of oocytes,
copy)
3
–
d
ay
4
–
d
ay
5
-
d
ay
6
-
d
ay
7-
d
ay
8-
d
ay
1
Healthy control
group
-
-
65
100
-
-
-
-
-
-
-
2
Patient Control
Group
-
-
65
60
15,6 16,9 21,6 18,6 16,4 17,2
-
3
Experimental
group
In
tr
ac
ox
o
ra
l
1
m
l p
er
1
li
te
r
of
w
at
er
65
100
10,1
9,9
7,3
5,4
2
1
95
4
Experimental
group
F
ur
az
ol
id
on
e
0.
5
g
pe
r
1
kg
o
f
fe
ed
65
95
12,2 11,9 10,8
6,8
3,2
2
75
According to the results of the study, the death of rabbits of the 3rd group with continuous
administration of drugs for 2 days was not observed. In the 4th group, 3 heads of rabbits died. In
the 2nd control group, 5 rabbits died. After the administration of the drugs, repeated coprological
studies were carried out according to the established scheme, when determining the activity of the
eimeriostatic action in terms of the intensity of separation of the eimeria cells, it was noted that the
effectiveness of the test drug
"Intracox oral"
in the 3rd group was 95%, and in the 4th group the
effectiveness of
furazolidone
was over 75%.
606
Ann. For. Res. 65(1): 602-607, 2022
DOI: 10.5281/zenodo.7213307
ANNALS OF FOREST RESEARCH
https://www.e-afr.org/
© ICAS 2022
Conclusion.
1. The results of the study show that coccidiosis is the most common invasive disease in rabbits.
2. It is important for the study, practice and production of the prevalence, diagnosis and modern
chemoprophylaxis of emirosis (coccidiosis).
3. Of the new eimeriostatic drugs, Introcox oral is highly effective and we recommend that it be
used in practice in an amount of 1 ml / 1 l of water.
4. Failure to keep rabbits in cages, and frequent cleaning of mangers and water containers will
prevent the spread of the disease.
5. The results of the study show that eimerosis (coccidiosis) of rabbits is widespread (extensity of
invasion averages 40.3%), and the effectiveness of "Introcox oral" from new eimeriostatic drugs
in the treatment and prevention of the disease was 95%.
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Ann. For. Res. 65(1): 602-607, 2022
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© ICAS 2022
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Picture 1. PE "Maxsudabonu business service" studies
Davlatov Ravshan Berdiyevich
- professor
ravshan.davlatov.65@mail.ru
Khushnazarov Alisher Khudoiyberdi o‘g‘li
– PhD student
isoqulovxudoyberdi@gmail.com
Khushnazarova Mohigul Ilhomovna
– student