Comparative analysis of intrauterine sedation and the treatment of delirium in the post-operative period of the wound and post-cardiac surgery
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Agzamkhodjaev, T., Tahirov, S., Nurmuhamedov, H., Mamatkulov, I., & Beknazarov, A. (2016). Comparative analysis of intrauterine sedation and the treatment of delirium in the post-operative period of the wound and post-cardiac surgery. in Library, 16(2), 47–50. Retrieved from https://inlibrary.uz/index.php/archive/article/view/19200
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Abstract
The purpose of the study was to evaluate the effectiveness of the selective α2-adrenoreceptor agonist dexmedetomidine for short-term controlled sedation and treatment of delirium in the early postoperative period in children after cardiac surgery. Material and Methods: Dexmedetomidine infusions were performed for sedative purposes against the background of anesthesia with Kktoprofen and trimeperidine in 28 children who underwent surgery for atrial and ventricular septal defects under general combined anesthesia and in 9 children with clinical manifestations of delirium in the early postoperative period. Results and discussion: against the background of infusions of dexmedetomidine in medium therapeutic doses, a moderate and mild level of sedation was registered, which lasted up to 8 hours. Pain syndrome did not exceed 1 point on the V\S scale in 96% of patients. Additional administration was required only in 23% of patients. Of the side effects, bradycardia (39%) and arterial hypotension (36%) were most often detected. Dexmedetomidine therapy provided the most optimal level of sedation compared with other drug combinations in children with delirium, as measured by the sedation-arousal and wakefulness scales.
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