The age is common risk factor for cardiovascular diseases (CVD). One of the main risk factors for ageing is biologic age of vessels or vessel ageing. Main mechanisms of vessel ageing are oxidative stress, chronic inflammation, endothelial disfunction, apoptosis of endothelial cells, demage of endothelial EPCs progenitory cells functions, replication ageing of endothelial cells, disregulation of circadian system, arterial stiffness. Understanding of the mechanisms that lead to ageing pathophyziological changes in vessels is important and necessary of for novel methods of patogenetic treatment
"Psychomotor" development refers to changes in a child's cognitive, emotional, motor, and social abilities from the beginning of life through the embryonic and neonatal periods, infancy, childhood, and adolescence. This happens in a wide variety of fields. Knowledge of typical child development and related theories and models is very useful for clinical practice, leading to the recognition of developmental disorders and how to treat them. A thorough but focused history and neurological examination remain the most important initial elements of neurological diagnosis at any age.
Subject of research: the evolution of English Grammars in the framework of information technologies development.
Purpose of work: the influence of information technologies to the constituents characteristics of English grammars in the process of evolution, the analyses of constituents of electronic English Grammars in comparison to traditional ones.
Methods of research: descriptive method, comparative method, expert-analythic method, observation method.
The results obtained and their novelty: the study of English Grammars in the framework of Information Technologies Development allows to clarify the achievements in the sphere of General and Applied Linguistics, the History of Linguistics, Text Linguistics, the Methods of Teaching Languages, allows to form the theoretical prerequisites in creation of electronic English Grammars, and defining the nature of new types of English Grammars.
Practical value: results of the dissertation can be used in creation of interactive electronic resources, in giving courses on Applied Linguistics, Text Linguistics, General Linguistics, the History of Linguistics and the Theory of Grammatical Description.
Degree of embed and economic effectivity. The main results of research and ideas arc reflected in scientific articles published by the candidate as well as her speeches at scientific conferences and arc implemented into teaching process of English language at the Academy of State and Social Construction under the President of the Republic of Uzbekistan and the Higher School of Business.
Field of application: creation of the new types of English Grammars, creation of interactive electronic resources, delivering courses of lectures on General Linguistics, the History of Linguistics, the Theory of Language and the courses on the methods of teaching.
This article describes the ways of reflection of historical events in created epics and some lyrical poems at literary environment of Kokand. In this regard, there was a study of epics such as “Umarnoma”, “Voqeoti Muhammadalikhon”, “Shahnomai devona Mutrib”, “Shahnomai devona Andalib”, “Zafarnomai Xudoyorkhon”, “Jangnomai Xudoyorkhon”, “Maktubchai Khon” along with compositions of poets such as Akmal, Nodira, Muqimi, Nasimi. The ways of reflection of historical events in poems were explained by examples.
Zamon jadallik bilan rivojlanayotgan bir paytda, insoniyatga o’z ta’sirini ko’rsatmay qolmayapti. Ma’lumotlarni ko’pligi, shovqin-suron, internet rivojlanishi va boshqalar inson psixikasiga o’z ta’sirini ko’rsatmoqda. Bugungi kunda antidepressant preparatlariga talab kuchaymoqda. Albatta preparatning nojoyi ta’siri kamligi, qabul qilish intervali uzoqligi va tabiiyligi ko’p taraflama qulayliklarga olib keladi. Ushbu ilmiy maqolada Supurgi oilasiga mansub Cistanche o'simliklarining toksik- farmakologik xususiyatlari keltirilgan. Hozirgi vaqtda mahalliy o'simliklardan samarali dorivor moddalarni topish juda muhim. Cistanche an'anaviy Xitoy tabobatida keng qo'llaniladi. Chet elda Cistanche tubulosa osteoporoz (OP), Altsgeymer kasalligi (AD) va erkaklar jinsiy disfunktsiyasini (MSD) davolashda keng qo'llaniladi. Cistanches Herba - buyrak etishmovchiligi, ayollarning bepushtligi, patologik ajralmalar va qarilikdagi qabziyatni davolash uchun qo’llaniladi. Yuqoridagilarni hisobga olgan holda, biz Oʻzbekiston Respublikasining Fargʻona viloyatida oʻsadigan Cistanche mongolica turidan tayyorlangan ekstraktning ba'zi farmakologik xususiyatlarini va o'tkir toksikligini, undan tashqari antideprassant xususiyatini tahlil qildik. Ushbu tadqiqot haqida ma'lumot quyida keltirilgan.
The influence of negative factors of biological, chemical and physical nature leads to changes in the activity of various systems of the human body [9,2,3]. Numerous studies have shown that the diversity and specificity of etiological factors of the production environment, their various combinations and ways of exposure to the organism reflect the characteristics of the development and course of occupational pathology, determine the specificity of their pathophysiological and pathomorphological nature
Analysis of risk factors and clinical-hemodynamic parameters of patients with ischemic heart disease and arterial hypertension. Among the risk factors encountered in the examined IHD +AH patients, smoking + obesity + alcohol coexistence was 50%, obesity + hypodynamics 23.6%, alcohol + smoking 17%, heredity + alcohol + smoking 9.44%. Patients experienced headache in 75% of cases, tinnitus in 64%, weakness in 59%, tachycardia in 45%, and dizziness in 41%. The VEM test was performed in both groups of patients, with a threshold of (99.8 ± 2.3) Wt in patients with IHD + AH and 10.9% in patients with IHD without AH (109 ± 3.8) Wt. was At the same time (load) the duration of stress was equal to the initial value in the group with IHD + AH (8.3 ± 1.8), while in patients with IHD without AH was 9.2 ± 2.3 and 10.8%.
It was found that in many neurological diseases, cognitive impairment is a complication of the underlying disease. Cognitive impairment also leads to early disability in patients and negatively affects quality of life. Therefore, it is possible to prevent the development of dementia in patients with exercise that stimulates cognitive functions
Age-related macular degeneration (AMD) is a progressive disease characterized by damage to the central zone of the retina, leading to blindness and disability, which is a medical and social problem. The aim of the study is to improve the organization of medical care for AMD by creating an electronic program for clinical examination of a patient with AMD.
The article analyzes the organization and activities of people’s universities, which were considered a mass form of continuous education of citizens in the country in the Soviet period and supplemented the system of political and economic education of workers and personnel experience.
This article analyzes the role of political parties in the formation of state bodies (legislative and executive branches), the positive features of a multi-party system, the place of political parties and elections in the formation of civil society, reforms in the electoral system, the electoral function of political parties, and the place of the electoral platform
The article points out the issues associate with combination of pharmaco-physiologic methods of treatment in complex treatment of glaucomatous optic neuropathy in condition with compensate intraocular pressure. There was informationabout main conceptions of neuroprotection and the role of retinalamin as a main biogenic stimulator from the citomedin group. It should be noted that, these days, hypotensive therapy is not enough effectively retain process of the progression of GON. It is more reasonable to use drugs directed to improve a blood supply in the optic nerve area, mainly via targeted delivery with a help of endonasal electrophoresis and percutaneous electrostimulation with ESOM apparatus that considerably improve a quality of patient`s life by retaining atrophic process
The oral cavity plays an important role in perceiving the environment, and its condition is an informative indicator that reflects changes in the state of the human body that is affected by environmental factors. Epoxy resins were first used in commercial trade in 1946 and today are used in various sectors of the national economy, including shipbuilding, chemical, automotive, road, construction, aviation, furniture, agriculture and household industries. [2, 3].
The study of dental disease in individuals exposed to harmful industrial chemicals shows that in many cases a general trend in the development of pathological processes in the oral cavity is observed. Dental caries and its complications, inflammatory diseases, as well as periodontal injury have an etiological connection with the violation of the oral microbiocenosis. The constant exposure of chemical compounds to the oral mucosa at low concentrations in the air can contribute to changes in saliva composition, microbiocenosis structure, which ultimately leads to a secondary deterioration of the hygienic condition of the oral cavity.
Несмотря на преимущества дентальной имплантации, имеются некоторые сложности в использовании этого метода у пациентов с заболеваниями, возникшими после перенесенной коронавирусной инфекции. Количество и качество костной ткани является важным фактором, который может отразиться на исходе лечения дефектов зубных рядов методом дентальной имплантации. Установлено, что с общим снижением костной массы в иериимплантационной зоне больных, страдающих хроническими заболеваниями и перенесенной инфекцией Кавид-19, уменьшаются темпы физиологической и репаративной регенерации, уменьшается удельный вес непосредственно костных структур и параллельно увеличивается доля губчатого компонента, а также отличается нарастанием примитивной грубоволокнистой кости и хондроидной зоны в имплантационной зоне.
Ушбу мақолада Республикамизда «Рақамли Ўзбекистон – 2030» стратегиясига мувофиқ иқтисодиёт тармоқлари ва ҳудудларини рақамлаштириш, электрон хизматларни жорий этиш, шунингдек, рақамли технологиялардан кенг фойдаланишни таъминлаш бўйича иқтисодиётнинг барча тармоқ ва соҳаларида комплекс чора-тадбирлар амалга оширилаётганлиги батафсил ёритиб берилган
In this research work, the analysis of the lifestyle of students showed the need to develop and carry out preventive and sanitary-educational work to eliminate and correct the identified negative trends. Mastering this profession requires not only the assimilation of certain skills. The volume of knowledge and skills implies a certain attitude towards life, makes high demands on the personal qualities of a person, and, last but not least, on his physical and mental health. In modern conditions of social, environmental, economic, and political instability of our society, student youth is under significant pressure from society and the environment. The widespread introduction of innovative technologies also has a significant impact on the rhythm of a person’s life and on his psychological state.