The age is common risk factor for cardiovascular diseases (CVD). One of the main risk factors for ageing is biologic age of vessels or vessel ageing. Main mechanisms of vessel ageing are oxidative stress, chronic inflammation, endothelial disfunction, apoptosis of endothelial cells, demage of endothelial EPCs progenitory cells functions, replication ageing of endothelial cells, disregulation of circadian system, arterial stiffness. Understanding of the mechanisms that lead to ageing pathophyziological changes in vessels is important and necessary of for novel methods of patogenetic treatment
Расстройства аутистического спектра (РАС) – это гетерогенные расстройства развития нервной системы, начинающиеся в раннем детстве и характеризующиеся дефицитом социального взаимодействия и ограниченными паттернами повторяющегося/стереотипного поведения. Могут проявляться ассоциированные симптомы, такие как гиперактивность, раздражительность, бессонница, судороги, нарушения функции желудочно-кишечного тракта и иммунной системы.
Бош мия қон-томир касалликлари тиббиётда ва иж тимоий ҳаётда долзарб муаммолардан бири бўлиб келмоқда. Ер юзида ЖССТ берган маълумотга кўра ҳар йили 15 млн.дан ортиқ аҳоли инсульт ташхиси билан рўйҳатга олинади, шуларнинг ярмидан кўпида 1 йил давомида ўлим ҳодисаси кузатилади. Тирик қолганларнинг 80%дан ортиғида ногиронлик келиб чиқади (27,26,19). Дастлабки 1-йилда инсульт ўтказганларнинг 5-25% ида қайта инсульт кузатилади, кейинги 5 йилда эса 20-40% беморларда кузатилади ( 21,8.). Такрорий инсульт натижасида эса 95-100% беморлар ногирон бўлиб қолишади ва уларнинг 65-80% и бегоналар ёрдамига мухтож бўладилар. 70% касалларда эса психик бузилишлар кузатилади (28). РАМН(РТФА) берган маълумотларга кўра ишемик инсульт(ИИ) билан касалланган беморларнинг 84,5% и 55 ёшдан юқори бўлган беморлар, эркаклар орасида бу кўрсаткич 40-55 ёшда 30% ни, аёллар орасида эса 40-60 ёшда 46,2% ни ташкил этади (6). Охирги йилларда инсультнинг бундай ёшариши бу муаммони нг долзарблигини янада оширмоқда.
Age-related macular degeneration (AMD) is one of the leading medical and social problems worldwide. The purpose of this study was to evaluate the effectiveness of drug prevention in patients with early-stage AMD luteinzeaxanthin containing vitamin and mineral complex. The clinical study included 50 patients of the main group who took lutein-zeaxanthin containing a vitamin and mineral complex 1 capsule 1 time a day for 3 months 2 times a year, for 3 consecutive years, and 50 patients of the control group who did not receive drug therapy. In the main group of patients, there was an increase in visual acuity, an improvement in indicators according to OCT data, and an improvement in the subjective perception of their own visual functions. At the same time, the patients of the control group had a deterioration in visual acuity, the progression of the disease according to OCT, which was manifested by the transition to the next stage of AMD. Conclusion: drug therapy of early-stage AMD has a preventive effect on the progression of the pathological process in the macular zone.
Subject of research: the evolution of English Grammars in the framework of information technologies development.
Purpose of work: the influence of information technologies to the constituents characteristics of English grammars in the process of evolution, the analyses of constituents of electronic English Grammars in comparison to traditional ones.
Methods of research: descriptive method, comparative method, expert-analythic method, observation method.
The results obtained and their novelty: the study of English Grammars in the framework of Information Technologies Development allows to clarify the achievements in the sphere of General and Applied Linguistics, the History of Linguistics, Text Linguistics, the Methods of Teaching Languages, allows to form the theoretical prerequisites in creation of electronic English Grammars, and defining the nature of new types of English Grammars.
Practical value: results of the dissertation can be used in creation of interactive electronic resources, in giving courses on Applied Linguistics, Text Linguistics, General Linguistics, the History of Linguistics and the Theory of Grammatical Description.
Degree of embed and economic effectivity. The main results of research and ideas arc reflected in scientific articles published by the candidate as well as her speeches at scientific conferences and arc implemented into teaching process of English language at the Academy of State and Social Construction under the President of the Republic of Uzbekistan and the Higher School of Business.
Field of application: creation of the new types of English Grammars, creation of interactive electronic resources, delivering courses of lectures on General Linguistics, the History of Linguistics, the Theory of Language and the courses on the methods of teaching.
"Psychomotor" development refers to changes in a child's cognitive, emotional, motor, and social abilities from the beginning of life through the embryonic and neonatal periods, infancy, childhood, and adolescence. This happens in a wide variety of fields. Knowledge of typical child development and related theories and models is very useful for clinical practice, leading to the recognition of developmental disorders and how to treat them. A thorough but focused history and neurological examination remain the most important initial elements of neurological diagnosis at any age.
Zamon jadallik bilan rivojlanayotgan bir paytda, insoniyatga o’z ta’sirini ko’rsatmay qolmayapti. Ma’lumotlarni ko’pligi, shovqin-suron, internet rivojlanishi va boshqalar inson psixikasiga o’z ta’sirini ko’rsatmoqda. Bugungi kunda antidepressant preparatlariga talab kuchaymoqda. Albatta preparatning nojoyi ta’siri kamligi, qabul qilish intervali uzoqligi va tabiiyligi ko’p taraflama qulayliklarga olib keladi. Ushbu ilmiy maqolada Supurgi oilasiga mansub Cistanche o'simliklarining toksik- farmakologik xususiyatlari keltirilgan. Hozirgi vaqtda mahalliy o'simliklardan samarali dorivor moddalarni topish juda muhim. Cistanche an'anaviy Xitoy tabobatida keng qo'llaniladi. Chet elda Cistanche tubulosa osteoporoz (OP), Altsgeymer kasalligi (AD) va erkaklar jinsiy disfunktsiyasini (MSD) davolashda keng qo'llaniladi. Cistanches Herba - buyrak etishmovchiligi, ayollarning bepushtligi, patologik ajralmalar va qarilikdagi qabziyatni davolash uchun qo’llaniladi. Yuqoridagilarni hisobga olgan holda, biz Oʻzbekiston Respublikasining Fargʻona viloyatida oʻsadigan Cistanche mongolica turidan tayyorlangan ekstraktning ba'zi farmakologik xususiyatlarini va o'tkir toksikligini, undan tashqari antideprassant xususiyatini tahlil qildik. Ushbu tadqiqot haqida ma'lumot quyida keltirilgan.
This article describes the ways of reflection of historical events in created epics and some lyrical poems at literary environment of Kokand. In this regard, there was a study of epics such as “Umarnoma”, “Voqeoti Muhammadalikhon”, “Shahnomai devona Mutrib”, “Shahnomai devona Andalib”, “Zafarnomai Xudoyorkhon”, “Jangnomai Xudoyorkhon”, “Maktubchai Khon” along with compositions of poets such as Akmal, Nodira, Muqimi, Nasimi. The ways of reflection of historical events in poems were explained by examples.
It was found that in many neurological diseases, cognitive impairment is a complication of the underlying disease. Cognitive impairment also leads to early disability in patients and negatively affects quality of life. Therefore, it is possible to prevent the development of dementia in patients with exercise that stimulates cognitive functions
Analysis of risk factors and clinical-hemodynamic parameters of patients with ischemic heart disease and arterial hypertension. Among the risk factors encountered in the examined IHD +AH patients, smoking + obesity + alcohol coexistence was 50%, obesity + hypodynamics 23.6%, alcohol + smoking 17%, heredity + alcohol + smoking 9.44%. Patients experienced headache in 75% of cases, tinnitus in 64%, weakness in 59%, tachycardia in 45%, and dizziness in 41%. The VEM test was performed in both groups of patients, with a threshold of (99.8 ± 2.3) Wt in patients with IHD + AH and 10.9% in patients with IHD without AH (109 ± 3.8) Wt. was At the same time (load) the duration of stress was equal to the initial value in the group with IHD + AH (8.3 ± 1.8), while in patients with IHD without AH was 9.2 ± 2.3 and 10.8%.
This article analyzes the role of political parties in the formation of state bodies (legislative and executive branches), the positive features of a multi-party system, the place of political parties and elections in the formation of civil society, reforms in the electoral system, the electoral function of political parties, and the place of the electoral platform
Age-related macular degeneration (AMD) is a progressive disease characterized by damage to the central zone of the retina, leading to blindness and disability, which is a medical and social problem. The aim of the study is to improve the organization of medical care for AMD by creating an electronic program for clinical examination of a patient with AMD.
The article analyzes the organization and activities of people’s universities, which were considered a mass form of continuous education of citizens in the country in the Soviet period and supplemented the system of political and economic education of workers and personnel experience.