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POTOMORPHALOGICAL DIFFERENTIAL
DIAGNOSTICS OF PULLOROSIS AND
STREPTOCOCCOS DISEASES IN POULTRY
Kiyamova Z. N.
Supporting Doctoral Student
Elmurodov B. A.
Scientific Leader, Professor
Veterinary Scientific Research Institute
Abstract
The article describes the co-occurrence, clinical signs and pathomorphological changes of
pullorosis and streptococcal diseases in chickens. Information on pathological changes in the div
of birds and their differential diagnosis is given.
Keywords
: Chicks, bacteria, pathogens, differential diagnosis, pullorosis, streptococcus,
pathomorphology, bacteriology, yellow peritonitis, diagnosis, dystrophy, necrotic processes,
inflammation.
Introduction
Relevance of the topic.
The co-occurrence of infectious streptococcosis and pullorosis among
poultry, especially chickens, poses problems for veterinary science and practice. Finding ways to
solve these problems and developing countermeasures is an urgent issue of the day. Decree of the
President of the Republic of Uzbekistan No. PF-60 of January 28, 2022 "On the new development
strategy of Uzbekistan for 2022-2026", No. PQ-4015 of November 13, 2018 "Further development
of poultry additional measures on the "Additional measures of state support of the livestock
industry", PQ-4576 of January 29, 2020, PQ-5146 of June 14, 2021 No. "On additional measures
aimed at the development of poultry farming and strengthening of the network food base", PQ-
121 dated February 8, 2022 "On measures for further development of livestock breeding and
strengthening of the food base", PQ-187 of March 31, 2022 "On the radical improvement of the
personnel training system in the field of veterinary and animal husbandry", PQ-281 of June 15,
2022 "Measures to further improve the state support system of the poultry industry" -events" and
other legal and regulatory documents related to this field, researches within this topic serve to a
certain extent.
In order to solve the above problems, the main goal of our scientific research is to determine the
mixed occurrence of pullorosis and streptococcal diseases in chickens, the level of their spread,
the causes of the origin of the diseases, the epizootic status, and to compare their
pathomorphological changes and differences from each other.
For the development of the poultry industry, it is necessary to create and implement new measures
to effectively fight infectious diseases among chickens. One of the most important problems facing
veterinary science is the development, improvement and implementation of measures to diagnose,
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prevent and combat infectious diseases that occur among poultry, especially chickens, and cause
great economic damage.
Pullorosis and streptococcal diseases of chickens are infectious diseases, septicemia and intestinal
disorders in chickens, and latent bacterial carriage in chickens. All types of birds are affected by
this disease. The main sources are sick and recovered birds, as well as wild birds, and in hatcheries
- rodents, blood-sucking insects and others. The causative agent of the disease is isolated from the
discharge from the beak of birds, from internal organs and feces.
Clinical symptoms of the disease, depending on the route of infection, the incubation period can
be from one day to one week. In this case, the clinical symptoms of each disease are very complex
in poultry. For example, in acute form - lethargy, drowsiness, rapid breathing, general weakness,
loss of appetite, nervous conditions, catarrhal-purulent or fibrinous conjunctivitis, clouding of the
cornea, diarrhea are observed. The litter is white, sometimes greenish-gray in color and smells
very unpleasant. The mortality rate is 70-80%. When the diseases are mixed, sometimes lameness,
swelling of the joints, signs of lung damage are noted in chicks.
The process of general clinical examination
of chicks.
Patholaganatomical examination process.
Bleeding in the large intestine.
Bleeding in the ovaries.
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Pathomorphological changes were detected depending on the age of the chicks and the form of
disease manifestation when the internal organs of birds that died of streptococcosis and pullorosis
were examined under natural conditions. When chickens were infected with streptococcus,
hemodynamic disturbances, degenerative changes and necrosis were observed in the liver, kidneys
and heart, followed by the formation of granulomas, hyperemia and edema in the lungs, catarrhal
enteritis, additional cuticulitis, catarrhal-fibrinous colitis in chickens co-infected with pullorosis. ,
hyperplasia of the spleen, degeneration of nerve cells develops. When chicks are infected with
pullorosis and streptococcus, there are urine salts in the urinary tract with enlarged kidneys,
granular necrotic areas are visible. Foci of necrosis are observed in parenchymatous organs. A
hard curd-like blue-white mass accumulates in the cecum. As a result of damage and inflammation
of ovaries and fallopian tubes (ovaritis, salpingitis), the presence of yellow peritonitis, cloacitis,
gray-white necrosis foci, development of dystrophic changes was observed in chickens.
Conclusions and Recommendations
:
Diseases were diagnosed on the basis of pathomorphological, bacteriological, microbiological,
serological and IFA, PCR test results and bioprobe methods. This disease was prevented as a result
of timely vaccination with an inactivated vaccine against poultry pullorosis. In the treatment or
prevention of the disease, a mixture of two anti-streptococcus drugs is successfully used:
sulfamethyl pyrimidine sodium (sulfamerazine) - 10.0 g and sulfaethyl sodium diazole (sulfaethi-
dol) - 10.0 g per 100 ml of distilled water. 5 ml of this solution is added to 1 liter of drinking water
every day for 4-5 days. The first drug is quickly absorbed through the intestinal wall, the second
is slow and maintains a certain therapeutic concentration.
As a result of the common occurrence of pullorosis and streptococcal diseases among poultry,
complex clinical and pathomorphological changes were observed in them. It is also advisable to
vaccinate diseases on time. It is better to prevent diseases than to cure them.
References
1. Бакулин В.А. Болезни птиц/ В.А. Бакулин. - СПб.: Искусство России, 2006. - 688 с.
2. Болезни домашних и селскохозяйственных птиц / Б. У. Келнек [и др.]; под ред. Б.У.
Келнека [и др.]; пер. с англ. И. Григорева [и др.]. - М.: АКВАРИУМ БУК, 2003. - 1232 с.
3. Громов И. Н. Клостридиозы птиц: патоморфологическая и дифференциалная
диагностика / И. Н. Громов // Ветеринарное дело. - 2018. - № 6 (84). - С. 26-31.
4. Аблов А.М. Cтрептококкозы млекопитающих и птиц и видовая характериcтика
возбудителей натерритории Прибайкаля / А.М. Аблов, Е.В. Анганов, А.C. Батомункуев //
Извеcтия Иркутcкого гоcударcтвенного универcитета. Cерия: биология, экология. – 2015.–
Т. 11. – C. 105–110
5. Brooks B.W., Perry M.B., Lutze-Wallace C.L. & Maclean L.L. (2008). Structural
characterization and serological specificities of lipopolysaccharides from Salmonella enterica
serovar gallinarum biovar pullorum standard, intermediate and variant antigenic type strains. Vet.
Microbiol, (4), 334–344.
6. Cha S., Jang D., Kim S., Park J. & Jang H. (2008). Rapid detection and discrimination of the
three Salmonella serotypes, S. Pullorum, S. Gallinarumand S. Enteritidis by PCR-RFLP of ITS
and fliC genes. Korean J. Poult. Sci. (1), 9–13.
Volume 2, Issue 3, March 2024
ISSN (E):
2938-3765
82 |
P a g e
7. Ниязов Ф.А., Дурдиев Ш.К., Алимарданов А.Ш. Заслон распространению заболеваний //
Ўзбекистон қишлоқ хўжалиги. 2008. № 6. C.26.
8. Ниязов Ф.А., Ибодуллаев Ф.И., Юсупов М.Г. Патоморфологические изменения в
организме кур при пуллорозе. // Зооветеринария 2008.№7, С.18.
9. Elmuradov, B. A. (2002). Detection of mixed bacterial infections in calves. Journal of
Agriculture of Uzbekistan. Tashkent, 3, 63.
10. Эльмурадов, Б. А. (2003). Смешанные инфекции телят. Ветеринарная патология, (2), 52-
53.
11. Azamov, V., Elmurodov, B., Parmanov, J., & Abdalimov, S. (2004). Changes in the intestinal
system in colibacillosis. In Proceedings of the Third Republican Scientific-Practical Conference,
Samarkand (pp. 9-12).
12. Abdalimov, S. A., Parmanov, J. M., & Elmuradov, B. A. (2004). Sheep pasteurellosis//Third
Res. Il-Amal. konf. ma'r. Collection of texts.
13. Элмуродов, Б. А. (2005). Клинические изменения при смешанных бактериальных
инфекциях птиц.
14. G’aniyev, I., & Elmuradov, B. A. (2008). Course and clinical signs of sheep pasteurellosis.
In Four. ilm.-amal. konf. ma'r. text collection. Samarkand (pp. 94-96).
15. Duskulov, V. M., Elmuradov, B., & Meyliev, M. (2018). Highly profitable sector of
beekeeping. Veterinary Medicine, 12.
16. Элмуродов, Б. А., Турдиев, А. К., & Набиева, Н. Куёнчилик укув кўлланма. Самарканд-
2018, 72-73.
17. Эльмурадов, Б. А., Наврузов, Н., & Курбонов, Ф. (2019). Патологоанатомические
изменения при смешанных бактериальных инфекциях птиц.
18. Эльмурадов, А., & Эльмурадов, Б. А. (2019). Содержание нуклеиновых кислот в стенках
двенадцатиперстной кишки у каракульских овец различного возраста и в разные сезоны
года.
19. Navruzov, N. I. The Role of Immunostimulants in the Prevention of Colibacillosis,
Salmonellosis and Pasteurellosis in Calves. International Journal on Integrated Education, 3(8),
232-234.
20. Элмуродов, Б. А., & Эшбуриев, С. Б. (2021). ТОВУҚЛАРДА МИНЕРАЛЛАР
АЛМАШИНУВИ
БУЗИЛИШЛАРИНИНГ
КЛИНИК
БЕЛГИЛАРИ. ВЕСТНИК
ВЕТЕРИНАРИИ И ЖИВОТНОВОДСТВА, 1(1).
21. Муродов, Х., Элмуродов, Б., Шодиева, У., & Ахмедов, Б. (2021). Профилактика и
лечение инфекционного ларинготрахеита птиц. in Library, 21(2).
22. Navruzov, N. I., Elmurodov, B. A., & Mamadullaev, G. K. (2021). THE ROLE OF
CHITOSAN IN THE PATHOMORPHOLOGY AND IMMUNOPROPHYLAXIS OF
COLIBASILLOSIS OF CALVES.
23. Ахмадалиева, Л. Х., Элмуродов, Б. А., & Орипов, А. О. (2021). ПРАВОВАЯ ОХРАНА
ЗДОРОВЬЯ ЖИВОТНЫХ И ЭКОСИСТЕМ В НИИ ВЕТЕРИНАРИИ. ББК 40.0 П78, 378.
24. Nabieva, N. A., Elmurodov, B. A., & Aktamov, U. B. (2022). Biochemical Changes in Blood
in Rabbit Pasteurella’s. Texas Journal of Medical Science, 13, 115-118.
25. Elmurodov, B. A., Navruzov, N. I., & Kiyamova, Z. N. (2022). Intervention of Bacterial
Diseases in Poultry. INTERNATIONAL JOURNAL OF BIOLOGICAL ENGINEERING AND
AGRICULTURE, 1(4), 8-12.
Volume 2, Issue 3, March 2024
ISSN (E):
2938-3765
83 |
P a g e
26. Элмуродов, Б. (2022). Ветеринария илм-фанининг истиқболлари ва соҳани
ривожлантиришдаги муҳим вазифалар. Перспективы развития ветеринарной науки и её
роль в обеспечении пищевой безопасности, 1(2), 462-464.
27. Элмуродов, Б., & Исмоилов, У. (2022). Молодняк животных в районах приаралья
течение колибактериоза и сальмонеллеза. Перспективы развития ветеринарной науки и её
роль в обеспечении пищевой безопасности, 1(1), 233-235.
28. Элмуродов, Б., & Исмоилов, У. (2022). Текст научной работы на тему Течение
колибактериоза и сальмонеллеза молодняка в Приаралье. Перспективы развития
ветеринарной науки и её роль в обеспечении пищевой безопасности, 1(2), 307-309.
29. Эльмурадов, Б. (2022). Перспективы ветеринарии и важные задачи развития
отрасли. Перспективы развития ветеринарной науки и её роль в обеспечении пищевой
безопасности, 1(1), 9-12.
30. Sh, N., Elmurodov, B. A., & Eshburiev, S. B. (2022). TUXUM YONALISHDAGI
TOVUQLAR
MAHSULDORLIGIGA
NOVAMIX
PREMIKSINING
TASIRI. AGROBIOTEXNOLOGIYA VA VETERINARIYA TIBBIYOTI ILMIY JURNALI,
476-479.
31. Набиева, Н., Элмуродов, Б., & Сайдуллаев, А. (2022). Эпизотология пастереллиоза
кроликов. Перспективы развития ветеринарной науки и её роль в обеспечении пищевой
безопасности, 1(1).
32. Hamraqulov, N. S. (2022). SYMPTOMS AND HEMATOLOGICAL INDICATORS OF
CALCIUM AND PHOSPHORUS EXCHANGE DISORDERS IN CHICKEN IN EGGLAYING
HENS. Conferencea, 92-94.
33. Султанова, И., & Элмурадов, Б. (2022). Течение и бактериологическое течение
сальмонеллы у кроликов методы проверки. Перспективы развития ветеринарной науки и её
роль в обеспечении пищевой безопасности, 1(2), 187-191.
34. BA, Elmurodov, et al. "Pathomorphological Changes in Poultry Pasteurellios, Pullorosis and
Colibacteriosis Diseases." (2023).
35. Aktamovich, E. B., Bakhtiyorovich, E. S., & Shokir, H. N. (2023). Prevention of Calcium
Phosphorus Exchange Disorders in Chickens. Web of Semantic: Universal Journal on Innovative
Education, 2(6), 222-228.
36. Мамадуллаев, Г. Х., Элмуродов, Б. А., Джураев, О. А., Джуракулов, О. К., & Файзиев,
У. М. (2023). РИФИЗОСТРЕП–НОВЫЙ КОМБИНИРОВАННЫЙ ПРЕПАРАТ ПРОТИВ
МИКОБАКТЕРИЙ ТУБЕРКУЛЁЗА. Эпизоотология Иммунобиология Фармакология
Санитария, (2), 52-57.
37. Navruzov, N. I., & Elmurodov, B. A. THE ROLE OF CHITOSAN SUCCINATE IN
COLIBACILLOSIS
OF
CALVES
AND
THE
EFFECT
ON
THE
IMMUNE
SYSTEM. СБОРНИК ТЕЗИСОВ, 50.
38. Nabieva, N. A., & Profissor, B. E. V. (2023). PATHOGISTOGRAM OF PASTEURELLOSIS
OF RABBITS. European International Journal of Multidisciplinary Research and Management
Studies, 3(01), 92-98.
39. Elmurodov, B. A., Abdalimov, S. H., & Sheralieva, I. D. Diseases of young animals Samarkand
2016.
Volume 2, Issue 3, March 2024
ISSN (E):
2938-3765
84 |
P a g e
40. Алламуродова, М., Киямова, З., & Элмуродов, Б. А. (2024). ИННОВАЦИОННЫЙ
ПОДХОД К ПРОФИЛАКТИКЕ ЗАБОЛЕВАНИЙ ЖИВОТНЫХ. World scientific research
journal, 25(1), 128-133.
41. Набиева, Н. А., & Элмуродов, Б. А. (2024). ҚУЁНЛАР ПАСТЕРЕЛЛЁЗИНИ
ДАВОЛАШДА АНТИБИОТИКЛАР САМАРАДОРЛИГИ. World scientific research
journal, 25(1), 134-140.
42. Navruzov, N. I., Kiyamova, Z. N., & Elmurodov, B. A. (2024). SALMONELLA PULLOROM
GALLINARIUM BILAN ZARARLANGAN JO ‘JALARDA PATOMOFOLOGIK O
‘ZGARISHLAR. World scientific research journal, 25(1), 141-151.
43. Элмуродов, А. А., Абдуллаева, Ю. У., & Абдуллаева, С. А. (2023). ЭФФЕКТИВНОСТЬ
ВЫРАЩИВАНИЯ СЕМЕННЫХ КЛУБНЕЙ СОРТОВ КАРТОФЕЛЯ IN VITRO В
УСЛОВИЯХ ЗЕРАВШАНСКОЙ ДОЛИНЫ. Бюллетень науки и практики, 9(1), 173-181.
44. Элмуродов, А. А., & Абдуллаева, Ю. У. ЭФФЕКТИВНОСТЬ ВЫРАЩИВАНИЯ
СЕМЕННЫХ КЛУБНЕЙ СОРТОВ КАРТОФЕЛЯ IN VITRO В УСЛОВИЯХ
ЗЕРАВШАНСКОЙ ДОЛИНЫ.
45. Элмуродов, Б. А., Наврузов, Н. И., Набиева, Н. А., Ахмадалиева, Л. X., & Киямова, З. Н.
Инновационные вакцины для профилактики пастереллеза кроликов и других животных.
In Современные достижения в решении актуальных проблем агропромышленного
комплекса: материалы международной научно-практической конференции, посвященной
100-летию Института экспериментальной ветеринарии им. СН Вышелесского (Минск, 15-
16 сентября 2022 г.) (pp. 282-284).
46. Davlatov, R. B., & Khushnazarov, A. K. (2024). Diagnosis and chemoprophylaxis of rabbit
eymeriosis. In E3S Web of Conferences (Vol. 480, p. 03020). EDP Sciences.
47. Khushnazarov, A. X. (2022). OBZOR LITERATURNYX DANNYX PO KHIMIOTERAPII
I KHIMIOPROPHYLAKTIKI EYMEROZA KROLIKOV. Journal of PEDAGOGS, 23(2), 83-
86.