№ 10(MPHAPP) (2025) THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE “MODERN PHARMACEUTICS: ACTUAL PROBLEMS AND PROSPECTS”

Статьи

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  DEVELOPMENT OF A METHODOLOGY FOR THE ANALYSIS OF SOME PSYCHOTROPIC SUBSTANCES BY THE TLC METHOD The study of medicinal products containing psychotropic substances should be carried out using a simple, accessible, and rapid method - thin-layer chromatography.

  M Abdullayeva , N Olimov , Z Sidametova , M Shermatova

  235-236

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  SURUNKALI VENOZ ETISHMOVCHILIGINI DAVOLASHDA QO’LLANILADIGAN DORI VOSITALARINING MARKETING TAHLILI Venoz etishmovchiligi — qon tomir tizimining eng keng tarqalgan kasalliklaridan biridir.

  G Umarova

  237

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  PROBLEMS AND OPPORTUNITIES OF AUTOMATING QUALITY CONTROL IN A MEDICINE LABORATORY Automation of quality control in laboratories is becoming an integral part of the production process. On the one hand, it increases the efficiency, accuracy, and speed of laboratory analysis. On the other hand, the implementation of automated systems faces a number of challenges that require a professional approach.

  H Adamenka

  238

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  STATE OF METROLOGICAL SUPPORT FOR VISCOSITY MEASUREMENT Today, viscosity measuring instruments are widely used in the oil industry, fuel industry, medicine, cosmetology, and other important industries for assessing product quality and safety indicators and controlling technological processes in production conditions.

  Kh Alikulova , F Jurayeva

  239-240

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  ETERMINATION OF MINERAL ELEMENTS IN THE ABOVE GROUND PART OF NONEA PULLA L. Nonea pulla L. is one of the promising medicinal plants, containing tannins, coumarins, organic acids, anthocyanins, vitamin A, ascorbic acid, amino acids, polysaccharides, flavonoids, alkaloids, and microelements, but this plant has not been sufficiently studied.

  L Bozorova , Sh Khalilova

  241-242

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  LOPHANTHUS ANISATUS (BENTH) ANALYSIS OF QUERCETIN CONTENT IN THE AERIAL PARTS According to the data reported in the literature, the raw material of lophanthus anisatus (Benth.) exhibits immunomodulatory activity and contributes to faster recovery from complications of pneumonia, bronchitis, and bronchial asthma.

  D Ibragimova , N Farmanova , S Ibragimova , D Jumaqulova

  243-244

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  ANALYSIS OF FREE AMINO ACIDS OF FRUITS OF LUFFA ECHINATA ROXB The Decree of the President of the Republic of Uzbekistan dated January 29, 2025 No. PF-13 “On additional measures for the accelerated development of the pharmaceutical industry” sets out priority tasks such as the development of the biologically active additives industry in order to rapidly develop the pharmaceutical industry, provide the population with medicines of guaranteed quality, safety and effectiveness, localize production, organize medicinal plant plantations to form raw material bases for industry enterprises, and launch projects for the processing of medicinal plants grown on these plantations by the end of 2026.

  A Ganiev , N Gulomjonova

  245-246

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  UFFA ECHINATA ROXB. MEVALARINING ERKIN AMINOKISLOTALARI TAXLILI O‘zbekiston Respublikasi Prezidentining 29 yanvar 2025 yildagi «Farmasevtika tarmog‘ini jadal rivojlantirishga oid qo‘shimcha chora-tadbirlar to‘g‘risida» gi PF-13-son Farmonida farmasevtika tarmog‘ini jadal rivojlantirish, aholini sifatli, xavfsizligi va samaradorligi kafolatlangan dori vositalari bilan ta'minlash maqsadida biologik faol qo‘shimchalar sanoatini rivojlantirish, ishlab chiqarishni mahalliylashtirish, soha korxonalariga xom ashyo bazalarini shakllantirishda dorivor o‘simliklar plantasiyalarini tashkil etish va 2026 yil yakuniga qadar ushbu plantasiyalarda yetishtirilgan dorivor o‘simliklarni qayta ishlash loyihalari ishga tushirilishi kabi ustuvor vazifalar belgilab berilgan.

  A Ganiev , N Gulomjonova

  247-248

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  ON THE STUDY OF THE FLAVONOIDS OF LADIGINIA BUCHARICA LIPSKIYI Within the flora of Uzbekistan, many wild-growing plants remain insufficiently and unevenly studied

  Kh Komilov , M Ikramova , M Mukhitdinova

  249-250

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  DETERMINATION OF THE AUTHENTICITY OF THE GLABRUS DRY EXTRACT For the test solution, 1.0 g of the powdered sample was dissolved in 10 ml of a methanol–water (70:30) mixture and filtered. Depending on the active components of the plant, different mobile-phase compositions were selected to separate various active substances.

  N Karayeva , Z Turdiyeva , N Abdullajonova

  251-252

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  PHYTOCHEMICAL STUDY OF COUMARINS IN THE AERIAL PARTS OF PRANGOS FEDTSCHENKOI (REGEL ET SCHMALH.) KOROV Coumarin compounds are derivatives of cis-ortho-hydroxycinnamic acids. They are known for their biological activities, particularly their anticoagulant effects, while furocoumarins act as photosensitizers, i.e., they increase skin sensitivity to UV radiation (applied in the treatment of vitiligo). From this perspective, the search for coumarin-containing plants, isolation of their bioactive compounds, identification of their chemical structures, and study of their pharmacological activity are highly relevant.

  Kh Komilov , M Ikramova , M Mukhitdinova

  253-254

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  MEDICINAL PLANTS GROWING IN UZBEKISTAN The traditional use of herbal medicines dates back to long-established historical traditions. Official medicine, based on the experience of folk medicine, confirmed, substantiated, selected, and systematized the most valuable and theoretically understandable information in practice and modern science.

  N Olimov , Z Sidametova , B Nabiev

  255

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  QUANTITATIVE DETERMINATION OF POLYHEXAMETHYLENE GUANIDINE HYDROCHLORIDE IN A COMBINED PHARMACEUTICAL FORMULATION The development of novel antibacterial agents represents a promising direction in modern medicine. The demand for such drugs is continuously increasing due to the growing bacterial resistance to existing antimicrobial agents.

  R Kravchenko, S Rzheuski

  256

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  DETERMINATION OF THE MONOSACCHARIDE COMPOSITION BY PAPER CHROMATOGRAPHY METHOD FROM ACORUS CALAMUS L., HELICHRYSI MARACANDICUM POP EX KIRP. AND AERVA LANATA L. Plant polysaccharides are multifunctional biopolymers with a wide range of pharmacological activities.

  L Mahmudova, R Khusainova

  257-258

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  DETERMINATION OF THE QUANTITY OF COBALT-30 IN THE CAPSULE "KOASK-30" BY THE MASS SPECTROMETRIC METHOD An analysis of the pricing and assortment policy in the market of antianemic drugs has shown that it is necessary to take measures to develop and introduce into production domestic substances and dosage forms,as well as diversification of regional local production through the development of product varieties and the introduction of import-substituting products.

  B Mukhamedova , M Sagatova

  259-260

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  PHYTOCHEMICAL ANALYSIS OF DRIED EXTRACT OBTAINED FROM PLANTS USED IN BILIARY TRACT AND LIVER DISEASES Currently, liver and gallbladder diseases are widespread among the population, often resulting from irregular eating habits, excessive consumption of fatty products, physical inactivity, and the stagnation of bile

  M Malikova , M Alihodjaeva

  261-262

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  PHYTOCHEMICAL STUDY OF COMMON BASIL LEAVES this work is aimed at studying the main active ingredients of basil leaves, which have anti-inflammatory, choleretic, antiseptic effects.

  M Xolmatova, D Pulatova, F Urmanova

  263

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  ANALYSIS OF THE TRACE ELEMENT COMPOSITION OF TOOTHPASTES The aim of the study is to determine the micro- and macronutrient composition of toothpastes from various price categories using atomic emission spectral analysis to assess their safety and effectiveness.

  M Radin , M Radin , S Barmashov

  264

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  APPLICATION OF THE IMMOBILISATION METHOD TO INCREASE THE STABILITY OF ENZYMES It should be noted that enzymes have reciprocal and opposite processes, which disrupts the stability of substances in combination with the second component.

  G Tillaeva , N Abduvositova , U Tillaeva , Z Rakhmanova

  265-266

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  RAMAN SPECTROSCOPIC IDENTIFICATION OF SULFAMETHOXAZOLE IN PHARMACEUTICAL DOSAGE FORMS Sulfonamides are a group of compounds with antibacterial activity that have been widely used in medicine since the early 20th century. These substances exert a bacteriostatic effect by inhibiting the growth and reproduction of microbial cells. The mechanism of action of sulfonamides is based on the disruption of the biosynthesis of essential metabolites in bacteria, such as folic acid and dihydrofolate.

  N Saidkarimova, A Yunuskhodjayev

  267-268

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  POLAR LIPIDS OF ACHILLEA MILLEFOLIUM L. LEAVES Achillea millefolium L. is a perennial halotolerant species widely distributed across Central Asia, the European part of the Russian Federation and Siberia, the Caucasus, Western Europe and other regions.

  Z Samandarova , N Yuldasheva , S Gusakova

  269-270

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  NEUTRAL LIPIDS OF THE AERIAL PART OF ARTEMISIA JUNCEA Artemisia juncea Kar. et Kir. (rush-like wormwood, family Asteraceae) is a perennial herbaceous halophytic plant growing on moderately saline soils and is one of the most widespread Artemisia species in the flora of Uzbekistan. A. juncea is widely used in folk and traditional medicine.

  Z Samandarova , N Yuldasheva , S Gusakova , S Nishanbayev

  271-272

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  COMPARATIVE QUALITY CONTROL AND STANDARDIZATION OF DICLOFENAC-CONTAINING MEDICINAL PRODUCTS IN TABLET FORM Diclofenac sodium and diclofenac potassium salts to inflammation against, pain leaver and antipyretic features because of medicine in practice wide applicable drugs to the point They are arthritis, rheumatism, neuralgia, muscles and in the joints the pains in reduction primary from tools is considered.

  M Shodmonova , F Rasulov

  273

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  PHYTOCHEMICAL ANALYSIS OF FLAVONOIDS IN HORSETAIL (EQUISETUM ARVENSE) Flavonoids, being an important group of plant secondary metabolites, play a key role in the physiological functioning of plants and have a wide range of biological activities, including antioxidant, anti-inflammatory, antibacterial and cardioprotective effects. Horsetail (Equisetum arvense) is one of the plants traditionally used in folk medicine, known for its medicinal properties due, among other things, to the presence of flavonoids

  G Hasanova

  274

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  STUDY OF THE BLACK SEA OLIVE (ELAEAGNUS ANGUSTIFOLIA) Elaeagnus angustifolia, also known as jida, is a species of oleaster found in Uzbekistan. Its leaves, seeds, and flowers, along with its fruits, contain a complex of biologically active substances.

  G Hasanova

  275-276

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