The paper identifies the clinical, functional and radiological features of COPD in diabetes mellitus, the possibility of predicting its development. The examined patients were divided into 3 groups: patients with COPD in combination with diabetes mellitus, patients with COPD and patients with diabetes mellitus. In the structure of COPD, the pulmonary component and systemic manifestations arc distinguished, which can aggravate the disease. The manifestations of diabetes mellitus are based on micro- and macroangiopathies that affect pulmonary microcirculation. When managing patients with COPD in combination with diabetes mellitus, attention was drawn to more pronounced clinical manifestations of respiratory failure (shortness of breath, participation in breathing of auxiliary muscles, hypoxemia), especially in stage III COPD, compared to patients with COPD. To diagnose microvascular lesions in patients with COPD and diabetes mellitus, to predict the course of nonspecific lung diseases, based on the specific results of the study, multispiral computed tomography was performed. In patients with COPD, the assessment of the degree of impaired ventilation in the lungs should be carried out under CT conditions performed in the inspiratory and expiratory phases. Diagnostically significant for COPD during computed tomography is a symptom of expiratory "air trap", in combination with expansion and deformation of bronchi of various sizes, up to broncho- and bronchioectasis. When MSCT in patients with COPD and diabetes mellitus, pathognomic changes characterizing microangiopathy and fibrotic changes. The clear-cut shape of microvessels is a specific X-ray morphological sign in patients with COPD in combination with diabetes mellitus.
The article examines the relationship between diabetes mellitus and dental health. The lack of knowledge of dentists and dental patients about diabetes is shown. The role of the dentist in the early diagnosis of diabetes mellitus and the features of the treatment of dental diseases in patients with diabetes are discussed.
Diabetes mellitus (DM) and complications associated with diabetes are one of the leading causes of death worldwide. The International Diabetes Federation (IDF) has estimated that 592 million people will suffer from diabetes by 2035. Therefore, it is vital to find a new biomolecule that can further help in the treatment of diabetes. For several decades, a persistent interest in the biological properties of melatonin (MT) has been maintained in biological science and medicine. In recent years, a lot of information has appeared about its participation in maintaining energy homeostasis and the genesis of diabetes mellitus. The purpose of this review is to study the pathogenetic mechanism of melatonin in diabetes mellitus
This article provides summary recommendations of some manuscripts related to Covid-19 and diabetes mellitus comorbidity. Manuscripts related to this topic were searched in PubMed. The article describes the mechanisms how COVID-19 may enhance complications in individuals with diabetes mellitus and providing special considerations on anti-diabetes drugs commonly used in patients with type 2 diabetes in view of COVID-19 developed by group of researches. These recommendations can be useful for those physicians who are involved in case management of Covid-19 and diabetes mellitus.
One of the frequent complications of diabetes mellitus (DM) is the lesion of human blood vessels, leading to the development of diabetic foot. Literature and daily practical observation show an increase of the rate of diabetic foot (30-70%), which raises the actuality of the problem of diabetic foot treatment. This article contains data concerning the results of surgical treatment of 151 patients with diabetes mellitus complicated by diabetic foot and purulent-necrotic soft tissue inflammation. Our work presents the basic principles of treatment of purulent-necrotic complications of diabetes mellitus. The effectiveness of local application of Acerbin solution and two-stage surgical tactics in the complex surgical treatment of purulent-necrotic complications of diabetes mellitus has been proved.
The purpose of the study is to study the correlation rate of the quality of life, electroneuromyography, doppler and neuro markers BNDF in the blood in patients with a type 2 of type with diabetic foot syndrome.
Methods: The following 2 groups of patients were formed: 1 gr. - SDS patients, neuropathic form -37 patients, 2 gr. - SDS patients, neuroichmic form -35 patients, 3 gr. - Control group, these are 20 healthy persons of the appropriate age and gender.
Results: In all groups of patients, the quality of life is significantly different in the FSHC questionnaire compared with the control group (p <0.05). In patients with a neuroecemic form of diabetic foot syndrome, a significant decrease was found (p <0.05). All indicators of doppler song vessels of legs compared with patients with neuropathic shape.
Revealed significant correlations of FSHK and laboratory and instrumental indicators. A correlation connection with the duration of the disease, the duration of the disease, the levels of glycemia of an empty stomach, the level of the glycated haemoglobin, BNDF in the blood, the speed of blood flow in the femoral artery, in the lower leg, is discovered.
The definition of neuromuscular transmission showed that the patients of the 1st and 2nd groups have a weak reduction in muscle contraction involuntarily. This confirmed the impairment of neuromuscular transmission in both groups.
Conclusions: 1) A questionnaire to determine the quality indicators - FSHK is the most sensitive and informative to determine the quality of life in patients with type 2 diabetes mellitus with neuropathic and neuroecemic forms
2) FSHP questionnaire can be used for dynamic assessment of type 2 diabetes patients with neuropathic and neuroecemic forms in outpatient clinical practice.
3) Revealed significant correlations of FSHK and laboratory and instrumental indicators. A correlation connection with the duration of the disease, the duration of the disease, the levels of glycemia on an empty stomach, the level of the glycated haemoglobin, BNDF in the blood, the speed of blood flow in the femoral artery, in the shin, M-answer when stimulating a tibial nerve.
The visual organ injuries in diabetes mellltus are an urgent problem-of ophthalmology to investigate. However, in our»Republic the studies of this kind are infriquent and do not use epidemiologic approach. Six hundred patients with diabetes mellltus of types I and II were examined, they being the residents of Tashkent and our examination revealed the visual organ changes. The eye fundus was injured in 83.68% of patients with dieletes. type I and in 84.53% of those with type II, the extent of the eye fundus injury being greater in IDDM (Insulin Dependent Diabetes Mellltus) than in IIDM ( Insulin Independent Diabetes Mellltus). The clinical analysis showed that the frequency of the lens clouding in patients with diabetes mellltus increased with the .age of the patients, duration of the disease and its severity. Me had developed the classification of the injuries of the eve fundus in patients with diatetes mellltus which-allows to choose the proper tactics of treatment and succession of specialists and measures at various stages of the treatment course. The integral assessment of the risk factors of diabetic retinopathy revealed that the risk factors in IDDM and IIDM are similar,but their influence on development of the disease is different. To improve prophylaxis of the retina injuries in patients with dia-betes mellltus-, we selected the following risk groups: "favourable prognosis", "attention", and " unfavourable prognosis". We also developed the criteria of time and frequency of examination of patients in these groups. The analysts of dynamics of morbidity rate for diabetes melli- tus by 2005 showed the further increase of this rate - in 1.4 times. Blindness in patients with I DOU is 5.65% and in those with IIDM - 11.11%. On the basis of the material described above, the neccessery conditions for organising the ophthalmo-diabetic service were formulated.
An estimated 190 million people worldwide have diabetes, and this figure could reach 300 million by 2025. Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia resulting from impaired insulin secretion, insulin action, or both. To date, the incidence of DM is growing catastrophically in all countries of the world without exception, acquiring the scale of a worldwide epidemic.
The peculiarities of the attitude of the individual to the disease and treatment in diabetes mellitus are analyzed in the article. The research is conducted in the frames of a biopsychosocial approach towards health and disease (G.Engel), V.N.Myasischev’s theory of attitudes. The tutorial “Attitude type towards disease” (L.Vasserman) was used as a research method.
At all stages of the development of medical science, there was a violation of the therapeutic order. As early as the Hippocratic era, the problem of loyalty and the patient's lying about taking the drug was an urgent issue. Despite the changes in medical practice and in-depth reforms, the problem of adherence to doctor's recommendations remains relevant even in the current period, over the past decade this direction has become the subject of independent scientific research not only in medical practice but also in clinical psychology.
The phenomenon of treatment adherence is considered in the science of psychology from the side of various approaches, theories, structures, and factors. Hence, there are loyalty models of biomedical, behavioral, communicative, cognitive, and self-management (e.g., L. Myers, K. Evidence, 1998; M.X. Karamyan, 2010).
I.E. Leppic gives a broad definition of compliance- basically: it represents the type of patient Hulk, the degree of complability, and the pursuit of purpose. In his views, the scientist includes the patient's taking the medicine on the Hulk, regular visits to the hospital, and proper adherence to the doctor's instructions. The absence of complacency can be explained in a narrow framework as follows: the patient takes the drug in the wrong dose (in very small quantities or overstates), how many times does not follow the procedure of administration and duration, or takes another drug that the doctor does not recommend at all. In particular, the issues of adherence to treatment in diabetes have not been studied by scientists from Uzbekistan. However, B.X. Shagazatova (2004) on the issue of improving the basics of medical social care and treatment-prevention measures, D.I. Ilkhamova (2003) – characteristics of the sex of the age of an individual in cardiovascular diseases, M.X. Karamyan-conducted research on the nature of the value relationship of the attitude to health.
An analysis of the work devoted to the attitude to treatment and commitment to therapy shows that, in general, the question of its basis in diabetes mellitus, in the second – of the connection between the commitment to treatment and the motivational – values of the individual is little studied. In other words, despite our understanding of the importance of psychological factors in the constructive formation of the attitude to treatment, research on the dependence of loyalty on individual-motivational characteristics was found in patients with Type 1 and Type 2 sugar diabetes.