Presentation: Reproductive wellbeing, kid wellbeing and nourishment are center needs for any
nation, all the more so for India, with the world's most noteworthy weight of maternal, infant, and
youngster passings.
Targets: To evaluate the interpretation wellbeing and youngster wellbeing depiction of the
characterized populace utilizing regenerative wellbeing and kid wellbeing markers in the greensward
execution zone of Rajeswari Medical College and Hospital.
Materials and strategies: A people group based cross-sectional investigation was led among ladies of
regenerative age gathering utilizing a pretested and semistructured survey which included
interpretation wellbeing and kid wellbeing markers.
Strategy for examination: Data product dissected utilizing Statistical Package for Social Sciences
programming.
The investigation of work environment wellbeing should consider an assorted arrangement of components including work measures, hardware, shields, preparing, guidelines, and strategies. Authoritative wellbeing society has been perceived as another significant factor in the examination of work environment security. The security culture present in any association can have a significant impact upon wellbeing practices and likelihood of setbacks. The appraisal of wellbeing society has been the focal point of various exploration projects in light of the fact that the capacity to recognize the pathologies inside security culture can successfully address underlying drivers of mishaps. Advancement of devices to comprehend and adequately survey security culture keeps on being a subject of extraordinary interest in the wellbeing sciences. Understanding the social factors that lead to clashes inside associations and result in accidents is basic to injury and ailment counteraction. Generally utilized clash examination procedures were analyzed for their likely application as wellbeing investigation devices. The Ishikawa Fishbone Dispersion Analysis system and the Social Cubism Discord Analysis Model were distinguished as possibly successful apparatuses for setback underlying driver examination and evaluation of authoritative security culture as a component of wellbeing examinations.
For studying reactance of an organism at various forms nephrotuberculosis, 237 patients have been twisted to complex clinic
- laboratory inspection. With the purpose of revealing of different combinations of genetic markers defined phenotypes haptoglobin, activity erythrocytes glucose -6 phosphatedehidrogenese, type inactivation (HINA). On combinations of a complex of these genetic markers defined 4 combinations of genetic markers: adverse, favorable, rather adverse and rather
favorable. Researches have shown high frequency of the widespread forms nephrotuberculosis at persons with adverse and rather adverse combinations of genetic markers. Definition on combination with chronic renal insufficiency of different combinations of genetic markers can be used for revealing groups of risk on the given disease
This study was carried out on the “Perceived effects of class size on student’s psychological wellbeing in the University of Bamenda”. The study soughts to examine the perceived impact of large class size on students’ Psychological wellbeing; to examine the extent to which perceived impact of small class size influence student psychological wellbeing. The survey research design was used and the sample size was made up of 354 students who were from a college, school and faculty in the University of Bamenda. The instrument used for data collection was a questionnaire. The data were analysed using Statistical Package for Social Science (SPSS version 23.0) with the aid of descriptive and inferential statistics. The descriptive statistical tools used were frequency count and percentages. The Spearman’s rho test was used in testing the hypotheses of the study. Findings indicated that: there was a significant and negative relationship between large class size and the students’ psychological wellbeing (P=0.021, <0.05). Finding equally revealed that there was a significant and positive relationship between small class size and the students’ psychological wellbeing (P=0.009, <0.05). It was recommended that the government should alongside recruiting more teachers, build more classes to reduce large and overcrowded classrooms so as to make the student to learn in a supportive and comfortable learning environment.
Introduction; Worldwide, young women and men suffer a disproportionate share of reproductive health problems, such as unplanned pregnancies, sexually transmitted diseases, including HIV/AIDS, and other serious reproductive health problems. Youth Reproductive Health Service is a special gift from the youth age group, young people all over the world are in need of much better education and health care related to reproduction.
Methodology; This cross-sectional community based descriptive study was conducted in West Hararghe, Gumbi Bordade woreda Arba Bordade Health Center, with the main objectives of assessing youth reproductive health service preferences and utilization. Based on probability proportionate to the population size of kebele, the lottery method was used to identify the study population by interviewing 239 youth selected by systematic sampling using per-structured questionnaires
Result-. A total of 239 youth aged 15-24, 221 responded to the structured questionnaire, out of which 114 (51.6%) were male, with a male to female ratio of 1.14:1. Among the study participants, 140 (63.3%) were aged 15-19, and 38 (17.2%) were married. In the assessment of utilization and preference of the health institution, 96(43.4%) of the respondents preferred to be served in governmental health institution and 69 (31.2%) of the youth indicated the need to rearrange in the existing health institution having separate youth health institution, and 93(42.1%) of the them preferred to be served by young and of the same sex.
Conclusions: -A high figure of the youth not served in the existing health institution for their reproductive health needs, even those who used to be served, they claimed that the existing health institutions were inconvenient and unattractive. Almost half of the respondents preferred the need for rearrangement of youth reproductive health institutions separately, and also to be served by young and the same sex health providers. Family health service, sexual education, partner relation guidance, information and education on STD/HIV AIDS and to having an information center were preferred by almost by all respondents.
The aim is to study the review of the literature review on autoimmune thyroiditis and violations of the reproductive function in women of fertile age
Methods. In total, 100 cases of Ait in women of fertile age with various disorders of the menstrual function (MF) and the reproductive system (PC) were studied. The average age of women was ranging from 18 to 45 years (31.5 ± 0.4).
All 100 patients were performed by a study spectrum, including the study of endocrine status (anthropometric - height, weight, waist volume, thighs, body weight index), general crystal, biochemical, hormonal (TSH, LG, FSH, prolactin, estradiol, progesterone, free thyroxine, antibodies to TPO and other - in the laboratory of radioimmune hormonal studies of the RSNPMC Endocrinology of the Ministry of Health of Ruz. In addition, they performed an ultrasound study of the brief and genital organs, an ECG, as well as a study of the quality of life on the questionnaire of The World Health Organization Quality Of Life (WHOQOL -Qol).
Research results. Depending on the body mass index (BMI), the patients were distributed into 2 groups: 1 group - patients with ait with soblinic hypothyroidism -48 (48.0%) patients, 2 groups - patients with AIT with manifestic hypothyroidism - 52 (52.0%) patients.
In the structure of violations of MC in women, the 1st groups were allowed -24.6%, secondary amenorrhea -12.5%. These patients had a history of miscarriage (12.5%), stillbirth (14.6%). Violations of reproductive function were not observed.
In the structure of violations of the MC in women, 2 groups were an olnognosorya -59.6%, the metrrahny frequency is 21.2%, secondary amenorrhea -19.2%. For this category of patients, a high frequency of violations of the reproductive system (53.9%) is characterized, of which: primary infertility was observed in 40.4% of cases, secondary infertility - 13.5% of cases. These patients had a history of miscarriage (32.8%), stillbirth (39.8%), butorous prevention of the fetus (22.7%).
Conclusions. 1) The first stage in the treatment of menstrual disorders and infertility in women with ait should be the correction of excess body weight. 2) Most often, the violation of the MC and the reproductive function was observed in patients with ait and 1 degree of obesity than with ait and normal body weight.
Topicality and demand of the subject of dissertation. Researches of human population genomic variety and scenarios of its genetic pool formation arc one of perspective directions of modem genetics. Prompt progress in this field has allowed defining the basic routes of continents settlement. However the information about Central Asian (CA) populations even on «classical» genetic markers has accidental, fragmentary character, and requires additional large-scale investigations. Besides, according to historical, archeological, paleontological and some anthropogenetic studies, given region was playing certain role in ancient moving of modem human ancestors throughout Eurasian continent. Therefore it is extremely important to summarize and perform complex assessment of new and collected data on Central Asian populations as practically there arc no multivariate analyses studies of given region as a complex population system.
In studies of human population genetic structure arc usually used various approaches allowing understanding concept of populations subdivision and character of genetic relationships between them. Among these techniques the prominent place belongs to approaches based on an assessment of genetic distances between populations with their subsequent analysis by multivariate statistics methods. For even more compelling picture of the relationships between the populations on tree diagram we composed «the genetic landscape» of area, where the description of population genetic structure is presented by equally spaced figures consistently consolidating populations according to their genetic distances from each other and thus creating a genetic landscape. This approach is not only a tool for elementary population boundary detection, but also can be effectively used for identification of borders and sizes of population as naturalistic unit.
Multigcnctic landscape is a collection of different genetic systems which arc specific to the region and ethnic groups, which have their geographical areas, their geographical, historical and cultural boundaries. Gene flows arc run through these conventional boundaries, but they arc less intense than in the limits of area. These limits arc ambiguous and fluid, but it is real. You can identify them by studying, for example, the structure of marriage migration. Therefore anthropogenesis of different populations will inevitably differ from each other. Ethnogenetic composition tends to change over time, from generation to generation, and hence there is a need to understand the structure of the genepool, not only at a given time, but also in the study of genetic processes that form and reform the gcncpooL In this regard, the studying of multigcnctic landscapes is in close contact with the demographics, medical and genetic ecology, anthropology, ethnology, archeology and history of the peoples, that is, with a range of areas, not only natural, but also the humanities knowleges.
Study of genomic diversity is important not only to address questions of origin and genetic history of different ethnic groups, but is also the basis for molecular epidemiology of hereditary and multifactor diseases. Each region is characterized by a specific set of common genetically determined diseases. To understand the causes of the prevalence of disease in different regions, and to develop approaches to their early DNA diagnosis and effective prevention, initially it is necessary to conduct population-based studies, which determine the development of the disease.
Purpose of research is to implement a comprehensive description of the structure of indigenous Central Asian populations genetic pool, examine demographic, phylogenetic and evolutionary features of Central Asian populations through the analysis of genetic variety of mtDNA, Y-chromosomal (NRY), autosomal, X-chromosomal microsatcllites and immunogcnetic variants of Helicobacter pylori (H.pylori) and hepatitis В virus (HB V).
To achieve this goal the following tasks of research is solved:
specification of immunogcnetic variants of H.pylori and HBV, allocated at the patients in Central Asian region, with the subsequent comparative phylogenetic analysis of H.pylori and HBV regional versions with those in other regions of the world;
examination of genetic variety and degree of genetic differentiation of Central Asian populations according to classical population-genetic objects -polymorphisms of mtDNA, Y-chromosomal, autosomal and X- chromosomal STRs;
assessment of the Western and East-Eurasian lines of population inheritance contribution to Central Asian populations’ genetic pool at regional, ethnic, sub-cthnic levels and in a level of elementary populations;
reviewing of character of regional populations relationships by genetic variety of mtDNA, autosomal, X-chromosomal, Y-chromosomal STRs markers in view of ethnographic, social and linguistic data;
evaluation of sex-specific genetic structure and the social organization according to polymorphisms of mtDNA, autosomal, X-chromosomal, Y-chromosomal markers in the region;
determination of ancient ways of migrations and scripts of formation of Central Asian populations according to mtDNA, autosomal, X-chromosomal, Y-chromosomal STRs markers and immunogcnetic variants of H.pylori and HBV',
evaluation of ethnogenetic position of studied Central Asian populations in the system of genetic pools of Eurasia and the world in general through comparative analysis of all studied population-genetic parameters.
Scientific novelty of dissertational research consists in the following:
for the first time was performed a study of genetic pool structure of 26 Central Asian populations from 6 ethnic groups as complete population systems using a wide range of genetic objects;
for the first time was made an assessment of informativeness of each type of genetic subjects. For the first time was received detailed characteristic of genetic pool structure of indigenous Central Asian population on the basis of variability lines of the spectrum of genetical objects;
for the first time was defined the ratio of Westem-and the East-Eurasian lines in a genepool of Central Asian population and were made an assessments of genetic variety level and genetic differentiation degree of regional populations as a whole;
for the first time phylogenetic analysis of major haplogroups of investigated genetic subjects was conducted;
for the first time the position of Central Asian population in population genetic pool system of surrounding regions and Eurasia in the whole was studied;
for the first time the evolutionary-adaptable mechanisms, necessary in the forecast of formations of multigenic pathologies in region were studied at 6 ethnoses of Central Asian.
CONCLUSION
1. H.pylori from Central Asian territory is similar to Western Europe isolates, and shaped by two ancestral populations genotype Ancestral Europe 1 (dominant) and Ancestral Europe2 and for AE1-genotype Central Asian region probably is the source. H.pylori from the territory of Central Asia form a separate cluster group: close relationship of Tadjik, Uzbek strains and Iranian isolates from the north of Iran is established. Kirghiz isolates were found to be closer to populations from territory of Siberia.
2. High diversity of HBV genotypes in Central Asia was found -4 genotypes (A, C, D, and G). Phylogenetic analysis of Central Asian genotype HBV-with options for other regions of the world showed a close relationship between the dominant genotype D (0,78), the D1-subtype with variants of the virus in Europe, the Middle East and Africa.
3. The rates of genetic affinity for STR-NRY in Kazakhs, Turkmens, Karakalpaks Turtkul at the level of the same lineage were high: 0,58 (p<0,001); 0,34 (p<0,01) and 0,77 (p<0,001), respectively. The coefficients of relationship at the level of clan for Kazakhs, Turkmens, Uzbeks and Karakalpaks from Kungrad and Turtkul were lower: 0,30 (r<0,01); 0,21 (p<0,001) and 0,40 (r<0,001); 0,07 (p<0,05) and 0,09 (p<0,05), respectively. At the level of the tribe, the indicators were negative for all Turkic populations: -0,02 (r<0,05);-0,04 (r<0,001);-0,07 (p<0,01); -0,0011 (r<0,1) and -0,10 (r<0,01), respectively.
4. The analysis of mtDNA HVS-1 showed that total rate of differentiation level for all populations was low: FST=0,013; p<0,0001. Level of diversity between groups was 0,6% (p<0,001) of the total variability. Parameter of genetic differences between Turkic and Indo-Iranian populations made 0,55% (p<0,0283) of the total genetic variability. The rate of genetic differentiation on a sub-ethnic level was significantly expressed in Indo-Iranian group (FST=0,0197;r<0,001) than among the Turkic-speaking (0,3%; p=0,10). In all populations, in general, wasn‟t detected the correlation between genetic and geographic distances at the global level on mtDNA HVS-1: r=0,00682; p=0,502.
5. Analysis of STR-NRY showed that the level of the genetic differentiation between ethnic groups was 5,6% (p<0,02); general differentiation between populations made RST=0,186 (p<0,001). Combined analysis, taking into account the language and way of life of Turkic and Indo Iranian populations, showed the general differences between the two groups – 9,1% Value of genetic differentiation when comparing the ethnos-ethnos was slightly lower than the level within ethnos: 5,6% among ethnic groups, 18,6%, and 13,7%-between populations within the ethnic group.
6. Analysis of heterozygosity (H) and the average number of pairwise differences (p) of mtDNA, were high in nomadic populations (av.H=0,99; av.p=5,29) and farmer populations (av.H=0,99; av.p=5,32). Heterozygosity (H) on Y- chromosome was lower in nomadic groups than in the agrarian – 0,86 and 0,99,respectively (p<0,01). Nomadic populations exhibit a higher level of population differentiation (RST) in comparison with farmers - 0,19 and 0,06, respectively (p<0,01). Indicators of population growth (r) were lower in nomadic populations compared with farmers - 1,004 and 1,008, respectively (p=0,056).
7. The level of genetic differentiation in all ethnic groups was higher on the Y chromosome in comparison with mtDNA. The farming populations showed no significant difference in the genetic differentiation FST (Y)=0,069 and FST (mtDNA)=0,034, while among patrilineal nomadic population the level of genetic diversity was higher in the male line of inheritance - FST(Y)=0,177 and FST (mtDNA)=0,010. Genetic diversity of population structure in patrilineal nomads on autosomal and X-linked markers were: FST (A)=0,008 (0,006-0,010) and FST (X)=0,011 (0,001-0,004) (H0: FST(A)=FST(X); H1: FST(A)>FST(X); p=0,02). In bilinear farmer populations the differences of autosomal and X-chromosomal markers were insignificant: FST (A)=0,014 (0,012-0,016) and FST (X)=0,013 (0,008-0,018 at p=0,36).
8. Analysis of mtDNA indicated that the age of expansion on the territory of Eurasia (τw) declined significantly from East to West (r=0,72; p<0,001). The age of expansion had a pronounced tendency to decrease from 30 thousand years in China to 17 thousand years in Western Europe. Age of expansion in Central Asia amounted to 26 thousand years. Results of expansion analysis on NRY also show a decrease in genetic diversity from the East to the West of Eurasia (r=0,49; p<0,001). In Central Asia this age was 16 thousand yrs. According STRs-NRYBatwing analysis of the minimal age of Uzbek population origin was 1232,71 yrs old (Ne=14088 (6765-23942); α=0,0108 (0,0065-0,0155)).
9. The apportionment of multilocus genetic variations among ethnic and linguistic groups of Central Asian populations showed that more than 98% of all variations were within the population (p<0,0001). Evaluation of the ethnic and linguistic affiliations in the observed variations showed reliable conformity - FST=0,007; p<0,0001 and FST=0,011; p<0,0001, respectively. We didn‟t find evidence of geographical isolation within each of the Turkic and Indo Iranian groups of populations (p=0,363 and p=0,772, respectively).
10. Analysis of multilocus allelic diversity (AR) and heterozygosity (He) showed differences among the Central Asian and other populations in allelic variety (χ2 =105,29; d.f.=25; p<0,0001) and heterozygosity (χ2=67,98; d.f.=25; p<0,0001). Population differentiation at multilocus analysis at populations of Central Asia is more pronounced than in the other regions of Eurasia: in European and Middle Eastern groups pairwise estimation of FST ranged from 0,011 to 0,015 and -0,008-0,021, respectively; in East-Asian groups from -0,011 to 0,046; and finally, in Central Asia these rates ranged from -0,004 to 0,056. Heterozygosity was significantly higher in the group of the Indo-Iranian populations than among Turkic-speaking (He=0,818 and He=0,787, respectively; Z=-4, 55; p<0,0001). According to multilocus analysis all 26 Central Asian populations slightly but significantly differed (FST=0,015; CI99%=0,011-0,018; p<0,01).
This study delves into the complex intersection of internal displacement and women's reproductive health in Nigeria. As the country grapples with ongoing internal displacement crises due to various factors, including conflict and environmental challenges, it becomes imperative to examine the repercussions on the reproductive health of displaced women. Through a comprehensive analysis of quantitative and qualitative data, this research sheds light on the unique challenges faced by internally displaced women, including access to healthcare, family planning, maternal care, and the psychosocial aspects of reproductive health. The findings highlight the resilience of displaced women and provide crucial insights for policymakers, healthcare providers, and organizations striving to support and improve the reproductive health outcomes of this vulnerable population.
Topicality and demand of the subject of dissertation. Bronchial asthma (BA) is one of the most common and serious diseases, which in the world suffer from 3 to 12% of the child population of the globe. Proportion of adolescents with asthma, is one third of all children with this disease. High prevalence of asthma in the numbers of teenagers, characteristics of the disease, age-related aspects of the functioning of the endocrine and immune systems of teenagers that cause difficulties which arise in the course of the diagnostic process, highlight the need to find innovative approaches to diagnosis and treatment of this disease.
It is known that the key immune mechanisms in the pathogenesis of the vast majority of AD cases is real and indisputable fact. Currently, considerable interest to researchers involved in the pathogenesis of positions of allergic diseases, especially asthma, along with IL-4 and IL-13 causes a number of other (IL-6, IL-8, IL-10, IL-5, INF-a and INF-y) immunoregulatory cytokines.
Genetic predisposition plays an important role in the development of allergic diseases. Currently available data on the relationship with asthma and associated with disease symptoms polymorphism approximately 150 genes. Important role as the main contender for the predisposition to asthma gene is a gene encoding flchain of high affinity receptor IgE. Interaction elevated levels of antigen-specific IgE with FceRip plays a central role in the pathogenesis of allergic asthma. Particularly attractive candidate gene asthma is also one of the enzyme genes biotransformation - GSTirl, encoding glutathione S-transferase and л1 express almost exclusively in the pulmonary tissue. This gene is located at the locus 11 ql 3, for which repeatedly shown clutch with atopic symptoms. Accumulated in the literature say about the relationship of gene polymorphism FceRI, GSTnl with different allergic diseases.
From this perspective, the study of immunological and genetic mechanisms of the pathogenesis of this disease for the construction of rational treatment and prevention emphasizes the relevance of this thesis research.
From the earliest days of independence, the country has successfully implemented state programs aimed at reforming the health care system. As a result, the targeted implementation of organizational health and research activities aimed at effective diagnosis, prevention and treatment of asthma among adolescents, with some success in the treatment of this disease in the country. However, now the problem of early diagnosis and the development of effective programs for treatment and prevention among adolescents with asthma remain one of the most important issues of modern health care. This research work was carried out in the framework of the tasks set by the Resolution of the Cabinet of Ministers of the Republic of Uzbekistan "On additional measures to improve the health of women and the younger generation," dated 25.01.2002 for the №32. In this regard, the need to deepen the information received about the state of cellular and humoral immunity among adolescents, asking pathogenetic informative immunogcnctic studies in asthma arc one of the important criteria demand the dissertation topic.
Purpose of research is study the immunological and genetic mechanisms of the pathogenesis of asthma in adolescents and form the basis of this plan rational diagnostic and therapeutic measures in this pathology.
In To achieve this goal the following tasks of research is solved:
to establish the clinical course of asthma in the population of adolescents living in the Samarkand region, in the early stages of the pathological process in the bronchopulmonary system.
explore the features of the state of cellular and humoral immunity, as well as activation markers in asthma in adolescence by determining the immunophenotype of lymphocytes in the peripheral blood.
to examine the level of production of immunorcgulatory cytokine interleukin-6 and interfcron-y and install them pathogenetic informative in asthma among adolescents.
to determine the features of distribution of allele and genotype frequencies of polymorphic variants of genes and FceRip GSTnl population Uzbek people with asthma, compared with the healthy part of the population.
examine the clinical and immunological aspects effectiveness of therapies using drugs and polioksidony tsikloferon in patients with asthma in adolescence.
on the basis of studies to develop a multivariate model of formation of bronchial asthma and develop an optimal algorithm for the diagnosis, treatment, prevention in adolescents with this pathological condition.
Scientific novelty of dissertational research consists in the following:
proposed introduction to the work of doctors teen clinics layered approach testing can significantly improve the detection rate of asthma in adolescence and optimize treatment and preventive measures in high-risk groups;
first defined the peculiar characteristics of the quantitative parameters of the immune status of patients with asthma in the cohort of adolescence and the corresponding proposed regulations and guidance documents for the healthy part of the adolescent population;
for the first time presents a comprehensive assessment of the cytokine profile of blood serum in bronchial asthma in adolescents. Specific features of products immunorcgulatory cytokines IL-6 and INF-y and their pathogenetic and regulatory information content in asthma among adolescents;
first analyzed the distribution of alleles and genotypes of polymorphic gene variants and gene FceRip GSTirl among patients with different phenotypic variants of AD and healthy individuals of Uzbek nationality, which resulted in the identified markers of increased risk or, conversely, resistance to the development of asthma in adolescents Uzbek ethnicity;
algorithms for phase diagnosis, treatment and prevention of asthma in adolescence in terms of disclosure of important moments of the pathogenesis of the disease, allowing to build a rational sequence of diagnostic search, aimed at verifying the diagnosis and expedient construction of preventive measures.
Conclusion
1. Set the frequency of occurrence of the disease and the structure of "asthma" in the arid zone among teens. Said pathology is recorded in 9,6% of the population surveyed adolescents, while the disease is more common among females. In the structure of the disease prevails periodical exposure and mild persistent form.
2. Identified by clinical features of asthma among adolescents living in the arid zone, indicate a high frequency of lesions of the bronchial tree association with allergic processes in other organs and tissues: in 73,9% of the AR, 53,7% with AK. 16,6% with BA and 14% with urticaria/angiocdcma.
3. Found that in the study population of patients with asthma adolescence occur expressed disturbances of the immune status, manifested deficit indicators as cell (CD3‘, CD4+, CD8 , CD16+), and humoral immunity (CD19 , IgA, IgG, IgM) and activation markers (CD23+, CD95). The immune status of patients with asthma in young people, adolescence has distinctive features, the depth of detected violations immunoreactivity was most pronounced in the younger age group.
4. In patients with bronchial asthma in adolescence revealed distinct changes in cell-cell interactions in the immune system: a significant increase in the content of Th2-cclls secreted IL-6 is a regulator of maturation of antibodies and immunoglobulin production itself, and vice versa reducing regulator activity of Th 1-cell cytokine INF-y.
5. It was found that the contents of cytokines IL-6, INF-y and in the peripheral blood is in communication with one pathogenic disease. It is shown that the lowest level of INF-y production in the scrum is characteristic of allergic clinical pathogenic variant asthma in adolescence. Adolescents suffering from predominantly infectious form of asthma, there is a sharp trend towards increased production of IL-6 in peripheral blood.
6. Revealed that markers of increased risk of allergic forms of asthma in adolescents Uzbek ethnicity arc genotype FceRip-109T/T allele FceRip-109T, low-risk markers - FcsRip-109C/C and allele Fc£Rip-109C. A high degree of cohesion genotype FcsRip-109T/T allele and FcsRip-109T with hereditary burden of asthma in the Uzbek population.
7. Among females ethnic Uzbek Association revealed lie-105 allele and genotype Ilc-105/Ilc-105 polymorphic gene locus GSTkI at high risk for asthma. Revealed that the genotype associated with the development Ilc-105/Ilc-105 allergic form of asthma in adolescents Uzbek population.
8. Complex therapy with adolescents’ patients with asthma ciklofcron and polyoxidonium, providing immunocorrective effect, enhances the clinical efficacy of basic therapy. In the study of prophylactic efficacy of immunomodulators positive indicators prevailed in the group of patients receiving polioksidony, necessitating its inclusion in the priority scheme of integrated treatment and prevention of asthma in adolescents.
Strength is a basic freedom. Value in wellbeing infers that in a perfect world everybody ought to have afair freedom to accomplish their full wellbeing potential and, all the more practically, that nobody should be distraught from accomplishing this potential. Tending to the multi-layered wellbeing needs of ethnically and socially different people in the United States is a mind boggling issue that requires inventive systems to diminish hazard factors and support defensive variables to progress greater well-being among people, families, and networks. With developing variety concerning various identities and ethnicities; and with critical changes in the star grouping of various of risk factors that can impact wellbeing results, it is basic that we outline vital endeavors that encourage better admittance to essential consideration, centered local area based projects, multi-disciplinary clinical and translational examination approaches, and wellbeing strategy backing drives that may improve people's life span and personal satisfaction.
Nominal capital has been perceived as one significant nominal determinant for wellbeing,
however we despite everything have constrained information about how it tends to be
utilized to clarify imbalance in wellbeing. This examination researched the connections
between singular nominal capital and self-evaluated wellbeing by sexual orientation and
instructive level, and investigated if access to nominal capital may clarify the watched
inconsistencies in self-appraised wellbeing among people and distinctive instructive
gatherings. Study structure: Strategies:
This comprehensive study, titled "Beyond Borders: Understanding the Effects of Internal Displacement on Women's Reproductive Health in Nigeria," delves into the multifaceted impact of internal displacement on the reproductive health of women within the Nigerian context. Utilizing a multidisciplinary approach, the research investigates the intersection of displacement, healthcare access, and reproductive well-being. Through a synthesis of qualitative and quantitative data, the study aims to provide valuable insights for policymakers, healthcare practitioners, and humanitarian organizations striving to address the unique challenges faced by internally displaced women.
The main factors of the current situation are: low awareness of the population in matters of sexual and reproductive health; lack of a system of sexual education for children and adolescents; the prevalence of sexually transmitted infections, especially among adolescents and young adults; high rates of teenage pregnancy and abortion; insufficient involvement of specialists in the process of protecting reproductive health and preparing for a planned pregnancy; insufficient saturation of the pharmaceutical market with high-quality contraceptives and their high cost; lack of research on the needs of the population in services for the protection of sexual and reproductive health.
Achievements of recent years in the study of molecular pathogenetic aspects of osteoporosis contributed to the search for the most specific and informative markers which reflect the intensity of remodeling processes. Although these markers are divided into synthesis and resorption markers, it should be kept in mind that under pathological conditions, when bone tissue remodeling processes are coupled and altered in one direction, any of the above markers will reflect the total rate of bone metabolism
The remarkable development of accessible data sources has enormously impacted the admittance to useable wellbeing data. As an outcome, restoratively one-sided data has become hard to use for navigation. In this paper, we consider these outcomes and present an improved technique for getting to wellbeing data continuously. The methodology includes the utilization of the vapnik Backing Vector Machine process for text grouping. The proposed technique was frameworked on php/mysql for web client. Trial arrangement shows that the strategy outflanks the pattern in the Accuracy, Review and F1 measures. An expansion utilizing the Gaussian portion is suggested in the paper.
The reason for this cross sectional review is to examine understudy impression of learning conditions at a significant Australian College. Different parts of climate are analyzed between courses, year levels, instructive foundations and sexual orientation. The positive discernment held by Flinders University wellbeing science understudies towards their schooling and learning conditions is ideally characteristic of comparative courses inside Australia and globally. While future investigations might assist with affirming this, the current discoveries offer an opportunity to investigate the fundamental reasons for this energy in more profundity just as think about likenesses and contrasts between the particular wellbeing science disciplines. Radiography and clinical imaging, word related treatment, drug store, nourishment and dietetics, physiotherapy and social work courses at Flinders University. Accommodation examining was utilized and scores were analyzed across gathering factors recognized by means of segment data.
Mechanical ventilation might be a day to day existence saving clinical consideration used in kids in PICU. These basically wiped out kids are in some cases broadly examined in PICU. Chest actinism is partner degree indispensable examination in these patients before ventilation.We concentrated on the effect of starting chest actinism on a definitive result of broadcasted kids.Retrospective. Setting: Tertiary consideration showing hospital.One hundred and 41 children were encased inside the review. Beginning chest actinism of the relative multitude of broadcasted kids was assessed and result of those children was correspond with the underlying actinism at confirmation.