The article deals with the treatment of primary disseminated breast cancer. Statistics are presented that in various countries around 10% of patients treat stage IV disease. In most cases, these are patients with T3-4 and multiple metastases in the lymph nodes. Metastases are most often detected in bones, lungs, and liver, and several organs are also affected. Standards have not yet been developed and therefore there are disagreements regarding the tactics of treating patients in this category. The article presents data from multicenter scientific research and clinical recommendations for the treatment of patients with primary disseminated breast cancer, taking into account the biological characteristics of the tumor.
Заболевание РМЖ сопровождается у больных тяжелым психологическим стрессом, который плохо поддается медикаментозной терапии. Радикальная мастэктомия не ведет к выздоровлению, поскольку «обменивает» рак на эстетический дефект [5,11,12]. Реконструктивнопластические операции занимают главное место в реабилитации больных РМЖ и лечении психических расстройств, связанных с утратой женственности и целостности собственного организма
This article presents a clinical case of a patient diagnosed with right-sided breast cancer T3N1M0, a condition after 6 courses of NPCP. Simultaneous radical subcutaneous mastectomy (PME) was performed with reconstruction by moving the TRAM flap. The following are the stages of the operation of simultaneous plastic surgery with the reconstruction of the TRAM flap in a schematic form and the results of this operation.
The article examines the degree of influence of political Islam on the processes of modernization, geopolitics, as well as socio-political development, including the need to create a scientific basis for regulating religious relations in Arab African countries, which have become a source of instability. In this context, political processes in North Africa and the Middle East are studied. The processes of social and political transformations have influenced the political systems of Tunisia, Egypt, Libya and other Gulf countries. The purpose of this article is to demonstrate that the wave of socio-political transformations that began in December 2010 in Tunisia and Algeria, called the “Arab Spring”, was a phenomenon caused by a difficult internal situation, as well as internal and external factors that triggered these events. Also, the result of social and religious unrest was the overthrow of the ruling regimes in Tunisia, Egypt, Libya. They led to changes in the ruling elite in Yemen and to this day the struggle continues between the Syrian government and the opposition. If the demonstrations against the regime in Tunisia, Egypt and Yemen were based on the internal socio-economic crisis, corruption of the ruling elite, the absence of genuine democratic freedoms and ethno-confessional confrontation, then the support of external forces was a key factor in Libya and Syria. These events spanned the entire Arab world, with the exception of Somalia, Mauritania and the Comoros, and led to a change in their political systems, structures, as well as the political future of states. The influence of the “Arab spring” on North Africa and the Middle East is not the same. As a result of the political and economic upheavals of the Arab Spring, countries such as Tunisia, Egypt, Yemen, Bahrain, Libya, Syria were seriously affected by them. And on Morocco, Jordan, Lebanon, Algeria, Kuwait, Saudi Arabia and Oman, they had only a superficial influence. At the same time, changes in the socio-political situation in each of the countries of the region directly affect their neighboring states. Recent events in the Middle East and North Africa have created a more complex and interdependent situation, which has led to changes in the relations of security and stability not only in neighboring regions, but also in the world.
The Tashkent Institute of improvement of doctors Results of treatment of 78 bladders sick by a cancer (BCa) with a lesion regional lymph nodes in stages T3-4 N1-2 MO are presented. The recurrent tumor is taped 19 (82,6 %) from 23 patients by whom the radical cystectomy (RCE) with standard lymph node dissection and the subsequent polychemotherapy (PCHT ) (I group was spent). On the average in 5,2 months after the treatment termination; in 11 group of 25 patients after RCE with dilated lymph node
dissection and the subsequent PCHT at 18 (72.0 %) the recurrent tumor, on the average in 4,8 months is taped. In 111 group after carrying out PCHT (without surgical treatment) advance of growth of a tumor after its regress and stabilization, was diagnosed at 27 (90,0 %) from 30
patients, on the average in 3,5 months. The survival rate median in 1 group of patients has made 9,4± 3,6 months, in II group - 12,5±4,2 months and in 111 group - 7,4 ± 2.9 months (p <0,05)