The study includes 557 patients with ulcer of the stomach and duodenal intestine complicated by bleeding. The control group was 290 patients, of which 48 patients with active bleeding were performed by standard endoscopic hemostasis techniques, and in 242 cases, when verifying stopping bleeding, endoscopy was limited to the diagnostic step with subsequent conservative patient management. The main group includes 267 patients in addition to endoscopic hemostasis with active bleeding (46 patients), the manipulation was supplemented with the implementation of the proposed method of endoscopic treatment of gastroduodenal bleeding of ulcerative genesis. When revealed bleeding (221 patients), endoscopic intervention was also accompanied by the implementation of the proposed method.
The application of the composite polymer material over the ulcerative defect contributed to a decrease in the frequency of the nearest recurrences of hemorrhagic syndrome from 9.0% to 1.9%, reduce the need to perform operational treatment from 6.6% to 1.1% and levity indicator from 1.7% up to 0.7%, which generally affected the increase in the share of patients discharged without complications from 90.7% to 97.8% and reducing the timing of the hospital phase of treatment.
Despite the significant breakthrough of obstetric science and practice in the second half of the 20th century and the beginning of the 21st century, the introduction of innovative methods, the rapid development of the pharmacological industry, the problem of obstetric bleeding remains one of the most urgent problems of obstetrics [2,5,7]. Of the 550-600 thousand maternal deaths, about 200,000 die from obstetric bleeding. Bleeding is in the leading positions among the so-called "big five" causes of maternal mortality [1,3,9,10] At the same time, 125 thousand women die due to massive obstetric bleeding, almost half die from uterine hypotension. The main reasons for the development of hypo and atonic bleeding may be the insufficiency of myometrial retraction and thrombosis in the vessels of the placental site, which has from 150 to 200 spiral arteries [4,5]
Purpose of the study. To assess the effectiveness of the use of hemostatic agent "GEMOGUBKA" for the prevention of bleeding from the bed of the gallbladder during traditional cholecystectomy. Methods. The study included 88 patients operated for acute calculous cholecystitis. Depending on the method of bleeding hemostasis, all patients were divided into 2 groups: in the study group (n=43), after cholecystectomy, 250-300 mg of "GEMOGUBKA" in the form of a fine powder was applied to the gallbladder bed for hemostasis; in the control group (n=45), after cholecystectomy, hemostasis was carried out by electrocoagulation of the gallbladder bed with a monopolar electrode. All patients in the postoperative period underwent control-dynamic ultrasound examination, study of the volume and nature of the discharge from the drains, as well as a biochemical blood tests. Results. In the study group, the average duration of hemostasis with bleeding from the bladder bed was 2,3±1,3 minutes, which is almost 2 times less than in the control group - 4,2±1,5 minutes. The duration of bed-days after surgery was 4,5±0,78 days and 6,3±2,06 days, respectively. The duration of the presence of the drainage tubes in the abdominal cavity in the study group was 1,49±0,88 days, while in the control group it was 4,24±1,38 days. The dynamics of the manifestation of cytolytic syndrome showed a low degree of intraoperative aggression during hemostasis in the study group, which significantly differed from the high rates of cytolysis in the control group. In the study group of patients, it was possible to significantly reduce the proportion of serous-hemorrhagic and hemorrhagic discharge from the drainage tube in comparison with patients in the control group. Conclusion. The use of the biocomposition in the form of the hemostatic drug "GEMOGUBKA" allowed both to reduce the duration of bleeding from the bed of the gallbladder, and the incidence of local inflammatory complications of the surgical site during traditional cholecystectomy.
A special place in the problem of abnormal uterine bleeding is occupied by the issues of qualitative diagnosis of patients with abnormal uterine bleeding, the cause of which is pathomorphological changes in the endomyometrium, such as: endometrial hyperplasia, uterine myoma, adenomyosis, a combination of fibroids and endometrial hyperplasia, a combination of adenomyosis and endometrial hyperplasia. Abnormal uterine bleeding is observed in 10-30% of women of reproductive age, in perimenopause - their frequency increases to 50%.
Меъда ва ичак системасидан қон кетиши хирургиянинг долзарб масалаларидан бири бўлиб қолмоқда ва унинг сабаби 50-60% холатларда яра касаллигидир. Муолажа тактикаси, хамда қон кетиш жараёнида даволаш услублари адабиётда кескин мунозараларга сабаб бўлиб келаяпти. Айрим муаллифлар актив тактика, яъни, тезкор амалиёт тарафдори бўлсалар, бошқалари актив назорат ва консерватив гемостатик тактика тарафдорларидир
The problem of the development of polyhydramnios is relevant in connection with the complications of pregnancy and childbirth, both for the mother and for the fetus. One of the most dangerous complications is hypotonic bleeding in the postpartum period, which leads to an increase in maternal morbidity and mortality. Among the causes of bleeding, polyhydramnios, the frequency of which reaches 1-8% of the total pool of pregnant women, occupies one of the leading positions. The aim of the study was to study the features of the clinic and the morphological structure of the uterine wall in polyhydramnios of varying severity. All this dictates the need to improve ways to prevent hypotonic postpartum bleeding in women with polyhydramnios.
Activation of the system of hemostasis in preeclampsia creates a premorbid background for thrombohemorrhagic complications. Hemostasis disorders increase the risk of severe bleeding during labor and cesarean section. During surgical interventions against the background of thrombocytopenia and thrombocytopathy (even with careful stopping of bleeding) bleeding is possible, including delayed bleeding. The same is observed in coagulation factor deficiency.
The problem of the development of polyhydramnios is relevant in connection with the complications of pregnancy and childbirth, both for the mother and for the fetus. One of the most dangerous complications is hypotonic bleeding in the postpartum period, which leads to an increase in maternal morbidity and mortality. Among the causes of bleeding, polyhydramnios, the frequency of which reaches 1–8% of the total pool of pregnant women, occupies one of the leading positions. The aim of the study was to study the features of the clinic and the morphological structure of the uterine wall in polyhydramnios of varying severity. All this dictates the need to improve ways to prevent hypotonic postpartum bleeding in women with polyhydramnios.
The Relapses gastroezofagale bleedings (GEK) beside sick with portal hypertension (PG) are one of
the the most complex problems of modern medicine. As of Worldwide organization of the public
health death-rate from cirrhosis liver and his (its) complications occupies for presentday day eighth
place in structure general mortality. Esohpago-gastric bleedings, forming from 5 before 42% all
gastrointestinal bleedings, are one of the main reasons to deaths sick with syndrome portal
hypertension. The Real danger of the syndrome portal hypertension is connected with bleeding from
varicose extended vein gullets and belly (VRVPZH), since death-rate from the first episode of the
bleeding forms 50-70 %. The High percent of the complications survival and low sick dictate need of
the improvement medical tacticians at bleedings from varicose extended vein gullets. At present for
stop and preventive maintenances of the bleedings from varicose extended вен gullets (VRVP) use
the facility an endockopic, medikamentoz, and surgical gemostaz. Our purpose to introduce in
practical person endockopic scleroterapy and alloying at bleedings under varicose extended вен
gullets. In consequence of which will is reached reduction of the relapse of the repeated bleeding
and complications, miniinvaziveness method and mortality.
Abstract. In ischemic heart disease (CHD), progressive disorders of the hemostasis system are corrected with shorter and longer antiplatelet therapy. However, recent studies have consistently demonstrated the development of up to 25% of all possible side effects and complications of anticoagulant and antiplatelet therapy.
Purpose of the study: to study the effect and complication of anticoagulant therapy on the state of the gastroduodenal zone in patients with ischemic heart disease.
Material and methods: 146 patients with ischemic heart disease (CHD), were examined, among them there were 12 (8.22%) patients with acute myocardial infarction (MI), 68 (46.57%) with progressive intense angina pectoris (PNS), intense angina pectoris (NS , functional class III-IV) - 66 (45.20%) people. The average age of the patients was 56.3 ± 2.4 years.
Results and its discussion: in the present study, the “ulcerative” history was assessed and whether there was a complication (bleeding, penetration or perforation). Detailing the data of the anamnesis made it possible to establish that the "ulcerative" anamnesis was detected only in 22.60% of cases. In other cases, as the duration of the course of the disease increases and, accordingly, the duration of the use of antiplatelet agents and anticoagulants, there is a directly proportional relationship to the increase in the frequency of gastropathy.