Milk production plays a crucial role in ensuring food security in India by providing a vital source of essential nutrients. This study analyzes the linkages between milk production and food security, focusing on the availability and accessibility of milk and dairy products, their nutritional significance, and the implications for livelihoods. The findings demonstrate a positive association between milk production and improved food security indicators. Increased milk production contributes to enhanced availability and accessibility of nutrient-rich food sources, addressing both macronutrient and micronutrient deficiencies. Moreover, milk production stimulates sustainable livelihoods, particularly for smallholder farmers, and promotes rural development through income generation and employment opportunities. However, challenges such as limited infrastructure and market linkages for dairy farmers exist. To capitalize on the linkages between milk production and food security, it is crucial to invest in sustainable practices, strengthen supply chains, and support smallholder farmers. These findings provide valuable insights for policymakers and stakeholders in shaping strategies and interventions to further enhance food security through milk production in India.
In modern abdominal surgery, one of the current areas for research continues to be the improvement of various options for plastic surgery of postoperative hernias. More than 2,100,000 operations for ventral hernia are performed annually in the world, and 42% of them are postoperative hernias. In recent years, there has been a clear trend toward the expanded use of various types of biological meshes in hernioplasty. “A pooled analysis of seven PCSTAR studies for incisional hernias using retromuscular mesh showed a hernia recurrence rate of 5.7%”[1]. The use of standard surgical interventions such as alloplasty in the onlay position does not solve the problem of early postoperative complications: seroma discharge, mesh migration, adhesive disease, high frequency of hernia recurrence, etc. At the same time, hernia repair with local tissue creates the problem of increased intra-abdominal pressure and late complications in the form of recurrent hernias. “An increase in postoperative intra-abdominal pressure leads to multiple organ failure, then abdominal compartment syndrome, and even death.” [2]. Currently, there is no consensus on the surgical approach for giant postoperative abdominal wall hernias, and therefore the need to continue to develop new technologies and improve There is no doubt about the tactics. In world practice, at present, the most relevant studies continue to be studies aimed at studying the morphological and functional aspects of recurrent postoperative ventral hernias; electron microscopy reveals ultrastructural destructive changes in skin cells, aponeurosis and muscles, which indicates morphofunctional insufficiency of abdominal wall tissues; issues of cell engineering are discussed new innovative materials, experimental studies are being carried out on animals testing the biotechnical properties, texture and elasticity of new polymers, research is being conducted on open approaches with division of the posterior component with the release of the transverse abdominis muscle and a retrograde mesh, robotic operations have begun. Modern aspects of the development of domestic healthcare include many measures aimed at improving the results of treatment of patients with postoperative ventral hernias and associated pathological conditions through the introduction of modern principles of intensive care and surgical tactics. The development strategy of New Uzbekistan for 2022-2026 in seven priority areas includes tasks to improve the quality of provision of qualified medical services to the population[3]. The implementation of these tasks, including by optimizing tactical and technical approaches to the choice of hernioplasty method, as well as the development of methods for the prevention of purulent-inflammatory complications in the field of alloplastic material, is one of the current areas of abdominal surgery and medicine in general, due to the high medical and social the significance of this pathology.
This dissertation research to a certain extent serves to fulfill the tasks approved by the Decree of the President of the Republic of Uzbekistan “On comprehensive measures to radically improve the healthcare system of the Republic of Uzbekistan” No. UP-5590 dated December 17, 2018, the Resolutions of the President of the Republic of Uzbekistan “On measures to transform the surgical service, improving the quality and expanding the scale of surgical operations in the regions" for No. PP-5254 dated October 4, 2021 and "On additional measures to ensure public health by further increasing the efficiency of medical prevention work" for No. PP-4891 dated November 12, 2020, and as well as other regulatory documents adopted in this area. Compliance of the research with the priority directions of development of science and technology of the republic. The dissertation research was carried out in accordance with the priority direction of development of science and technology of the VI Republic “Medicine and Pharmacology”. Review of foreign scientific research on the topic of the dissertation.[4] Research work aimed at improving the quality of therapeutic and preventive care for patients with ventral hernias, carried out by many leading scientific centers and higher educational institutions in the world, including the Department of Surgical and Perioperative Sciences, Umeå University, Umeå (Sweden), Department of Surgery, Kingston General Hospital, 76 Stuart Street, Kingston (Sweden). nada), Department of Surgery, Helsinki University Hospital, Helsinki ( Finland), Service de chirurgie digestive et oncologique, CHU d'Amiens (France), Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Tulsa (USA), Department of Surgery, Howard University College of Medicine, Washington (USA) , Yong Loo Lin School of Medicine, National University of Singapore (Singapore), Department of Surgery, Michigan Medicine, Ann Arbor, MI, USA; University of Calgary, Calgary (Canada), Division of Plastic Surgery, Perelman School of Medicine at the University of Pennsylvania, University of Pennsylvania Health System, Philadelphia (USA), Brigham and Women's/Faulkner Hospital, Harvard Medical School, Boston (USA) , Department of Surgical Sciences, Uppsala University Hospital, Uppsala (Sweden), Department of Surgery, University of Texas Health Sciences Center at Houston, Houston (USA), Department of Surgery, Erasmus University Medical Center Rotterdam, Rotterdam (Netherlands), Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University, Fukuoka (Japan), National Medical Research Center for Surgery named after A.V. Vishnevsky" (Russia), Republican Scientific Center for Emergency Medical Care (Uzbekistan), Tashkent Medical Academy (Uzbekistan), Republican Specialized Scientific and Practical Medical Center for Surgery named after Academician V. Vakhidov (Uzbekistan).
As a result of studies conducted around the world to increase the effectiveness of alloplasty for postoperative ventral hernias and reduce the risk of complications in the postoperative period, a number of scientific results were obtained, including: it was determined that patients who underwent reconstruction of the abdominal wall have an increased risk of postoperative respiratory failure, understanding the epidemiology of this complication can improve prevention (the Division of Plastic and Reconstructive Surgery, Department of Surgery, Oregon Health & Science University, USA); It has been proven that the larger the hernia, the higher the risk of early surgical complications, including such as respiratory decompensation, since hernias often increase in size over time, delaying surgery can lead to an increase in the size of the hernia and, therefore, a greater risk of complications (CentreforDigestiveDiseases, KarolinskaUniversityHospital, Stockholm, Sweden); it has been shown that the ratio of the hernia volume to the volume of the abdominal cavity <20% is an independent factor in tension-free closure, which justifies the interest in preoperative volumetry to adapt the tactics of surgical care (Servicedechirurgiegénérale, digestiveetendocrinienne, CHU LyonSud, HospicescivilsdeLyon, France); It has been determined that in patients undergoing elective laparoscopic hernia repair, predictors of mortality are older age and certain concomitant diseases: congestive heart failure, pulmonary circulatory disorders, coagulopathy, liver disease, metastatic cancer, neurological disorders and paralysis (Department of Surgery, College of Medicine, University of Oklahoma, Tulsa , USA); Older age, ascites, preoperative renal and pulmonary insufficiency have been found to be independent predictors of 30-day mortality, and in the presence of these risk factors, conservative treatment should be seriously considered (Department of Surgery, University of Kentucky College of Medicine, Lexington, USA); The American College of Surgeons (ACS) Universal Surgical Risk Calculator has been shown to accurately predict thirty-day outcomes, including major complications: venous thromboembolism, medical morbidity, surgical site infection, unplanned reoperation, mortality, and length of hospital stay (Department of Plastic Surgery, Brown University and Rhode Island Hospital, Providence, USA). At the present time in the world, the most relevant research in surgery continues to be the development of new methods of hernioplasty for large and giant ventral hernias, each of which has its own pros and cons depending on the complexity of implementation, the risk of postoperative complications and relapse, large randomized clinical trials are being conducted, comparing existing methods of traditional hernioplasty with laparoscopic access and robotic surgery, which has become increasingly widespread in the last 10 years, a search is being made for new synthetic and biological materials developed for the production and use of composite meshes that have the necessary strength and the ability to prevent fatal local complications in a contaminated environment. However, despite technical advances in this field, no modern hernia repair method or prosthesis meets all the requirements. One of the key problems is that existing synthetic endoprostheses do not have sufficient elasticity, resistance to infection, high mechanical strength and integrity over a long period of time. Further research into these clinical aspects will undoubtedly improve the current understanding of the capabilities of biocompatible endoprostheses and will make it possible to develop an optimal method for their placement during allohernioplasty. The degree of knowledge of the problem. The current period of development of abdominal surgery is characterized by an emphasis on the problems of the effectiveness of introducing new installation methods and techniques for attaching bioprostheses, options for various suture materials to determine the most promising directions for the development of these technologies [5]. Researchers led by BittnerR.[6] (2019) state that a giant postoperative abdominal wall hernia, the maximum diameter of which exceeds 12 cm or the ratio of the volume of the hernial sac to the abdominal cavity more than 20%, is difficult to treat, with a high recurrence rate and a large number of complications. One of the most challenging problems is that after the hernia contents return to the abdominal cavity, postoperative intra-abdominal pressure will increase, leading to multiple organ failure, then abdominal compartment syndrome (ACS), and even death. There is currently no agreement on the surgical approach for these giant incisional abdominal wall hernias. To prevent recurrences, some articles recommend placing the hernia mesh in the sublayer position and or linings (KirkpatrickAW.)[7]. According to CornetteB.[8], to prevent recurrence, it is recommended to place the hernia mesh in a sublayer or underlay position, and to achieve better mesh expansion, a component separation technique (CST) may be a suitable solution, but with a significant risk of complications and recurrence. JensenKK, et al. believe that truly successful giant hernia repair requires effective bridging or augmentation that will prevent recurrence with an acceptable risk of complications[9]. Another pressing issue in abdominal surgery is that patients with incisional hernias are extremely difficult to treat due to a number of factors including obesity, previous hernia repair, previous mesh placement, domain loss, and other variables.
The approach to patients with incisional hernias has changed significantly over the past 20 years due to both advances in mesh technology and surgical approaches. Key factors for successful outcome include modification of risk factors preoperatively, such as smoking cessation and weight loss, selection of mesh appropriate for the type of hernia and planned mesh location, and wide mesh coverage beyond the hernia defect. New techniques such as transabdominal muscle release and component separation with retrograde mesh placement and robotic approaches to abdominal wall hernia are increasingly being used in these patients[10]. Recent years have seen an increase in the number of biological meshes available for abdominal wall hernia repair. Biological meshes typically consist of materials obtained from humans, pigs, or cattle. The rationale for using biological meshes is that they can act as a scaffold for the growth of natural tissues. In addition, there are absorbable synthetic meshes that have properties similar to those of biological meshes, but with theoretically less risk because they are not derived from animal or human material. The choice of mesh for a ventral hernia depends on many factors, which include both the properties of the mesh and its location, for example, whether it should be placed intraperitoneally, preperitoneally, or retrorectus. BaierKF[11](2021) believes that the guiding principle should be to avoid placing uncoated polypropylene mesh in an intraperitoneal location where it may be in direct contact with internal organs. In addition, the type of hernia defect is another risk factor, such as whether the wound is clean or dirty, and whether the repair is performed with a bridge or abutment. Lightweight or biologic meshes to bridge the defect should be avoided due to increased recurrence rates. Holihan JL [12] (2016), Hodgkinson JD [13] (2018) believe that the principle of anatomical restoration to achieve a reliable, tension-free repair with reinforced mesh reduces the incidence of early postoperative complications and late recurrence of hernia compared with bridging mesh. The analysis of the literature concerning the theoretical aspects and clinical experience of using technologies for improving modern synthetic and biological prostheses that can provide a better plastic effect, as well as methods for preventing recurrence of ventral hernias, indicates that this is one of the priority areas in modern abdominal surgery. An unresolved issue remains the choice of the optimal endoprosthesis, which is highly effective and meets international standards for such properties as biological inertness and mechanical strength, as well as the method of positioning the mesh in relation to the layers of the abdominal wall. Considering that many of the allohernioplasty methods used today are not without drawbacks, the current direction is the development of new methods of repair for giant ventral hernias and methods for the prevention of postoperative complications in conditions of a contaminated wound, with justification of their effectiveness in a clinical experimental study. The connection between the dissertation research and the research plans of the research institution where the dissertation was completed. The dissertation research was carried out within the framework of the research work plan of the State Institution “RSNPMCH named after. acad. V. Vakhidov" under the project AL-422105574 "Development of new biocompatible mesh implants made of composite materials for reconstructive surgery of abdominal and diaphragmatic hernias" (2022-2024).
The purpose of the study is to improve the results of surgical treatment of large and giant postoperative ventral hernias by introducing new laser technologies and improving the tactical and technical aspects of surgical treatment. Objectives of the study: to study the structure of immediate complications after various types of prosthetic plastic surgery; to clarify the influence of obesity factors, primary or repeat hernioplasty on the incidence of immediate and long-term complications; to evaluate the role of the immediate complicated course of the postoperative period in the incidence of long-term complications of hernioplasty; to improve the technical aspects of alloplasty for large and giant postoperative ventral hernias (POVH); to improve the technique of photodynamic therapy (PDT) of the wound surface after prosthetic plastic surgery; to study in an experiment the effectiveness of using the proposed technique of alloplasty and PDT; evaluate the morphological features of the condition of tissues during prosthetic plastic surgery using the proposed method; in a comparative aspect, evaluate the clinical effectiveness of the proposed alloplasty options in the immediate and long-term periods. The object of the study was the results of allohernioplasty in 448 patients with extensive (large) and giant POVH, who were operated on at the surgical department of the 1st clinic of the Samarkand State Medical Institute in the period from 2012 to 2021, as well as experimental animals on which the effectiveness was assessed developed a technique for prosthetic repair of postoperative ventral hernias and applied the technique of photodynamic therapy.
The subject of the study is to analyze the effectiveness of the developed alloplasty of postoperative ventral hernias and intraoperative photodynamic therapy in abdominal surgery in experiments and in the clinic. Research methods. To achieve the goal of the study and solve the assigned problems, general clinical, instrumental, biotechnological, experimental, histomorphological, microbiological and statistical research methods were used. The scientific novelty of the study is as follows: it was established that the need for extensive tissue mobilization and, as a consequence, the intersection of lymphatic capillaries during implantation of the prosthesis in the onlay position, as well as the lack of sufficient resorption function of the hernial sac in the inlay position causes a high risk of the formation of clinically significant seromas; It was determined that with prosthetic hernioplasty, along with the volume of the defect, the type of plastic surgery and the degree of obesity, the most significant predictor of the risk of developing immediate complications is the factor of re-intervention in case of recurrent hernia with the presence of a “dormant infection” hidden in the remaining ligature granulomas or scar tissue; the structure and clinical features of the course of long-term complications of hernioplasty for giant and extensive hernias were clarified, taking into account the results of the immediate postoperative period, as well as the option of fixing the prosthesis, primary or repeated hernioplasty and the degree of obesity; the method of surgery for large hernias of the anterior abdominal wall has been improved, characterized by a combination of factors such as the formation of tension-free prosthetic repair, preservation of local resorptive function to prevent the development of fluid accumulations and reducing the risk of infection; the method of preventing the development or progression of wound infection during alloplasty of ventral hernias has been improved, aimed at enhancing the antibacterial effect and stimulating reparative activity through the photosensitizing and photodynamic effect of low-energy laser radiation; It was determined in an experimental model of prosthetic plastic surgery that the proposed method of fixing the prosthesis in combination with the use of the effect of photodynamic therapy through laser radiation helps to enhance reparative processes with a reduced risk of wound complications; It has been proven that all methods of antiseptic exposure and laser stimulation of the wound surface after prosthetic plastic surgery enhance preventive measures against the development of local infection, but are ineffective in the case of an already developed purulent-inflammatory process against the background of the use of alloplastic material. The practical results of the study are as follows: it has been determined that the implantation of synthetic materials for giant and extensive hernias is accompanied by a significant number of wound complications caused by both the surgical technique itself and the reaction of surrounding tissues to a foreign body, requiring improvement of tactical and technical approaches when performing hernioplasty; it was clarified that scar-degenerative changes in the tissues of the aponeurosis in giant and extensive hernias are a predisposing factor to the occurrence of post-prosthetic hernias, especially when implanting the prosthesis in the “inlay” position and, accordingly, require increasing the efficiency of their fixation and engraftment, as well as reducing the risk of developing local complications; it was determined based on the data of an experimental study that the proposed method of alloplasty for large ventral hernias makes it possible to achieve adequate reconstruction of the anterior abdominal wall, reduce the incidence of infection in the wound, and also use a smaller size of prosthetic material; it was determined that the proposed method of tension-free repair of large hernias of the anterior abdominal wall with strengthening of the aponeurosis with a mesh implant allows maintaining physiology, reducing the number of complications, shortening treatment time and reducing the risk of hernia recurrence; It has been determined that the proposed method for preventing the development or progression of wound infection during alloplasty of ventral hernias can reduce the frequency of suppuration, shorten the treatment time and the likelihood of relapse; It has been proven that the use of the proposed tactical and technical aspects of prosthetic repair for postoperative ventral hernias can reduce the incidence of specific complications, reduce rehabilitation time and the risk of hernia recurrence. Reliability of the research results. The reliability of the results is justified by the use of objective criteria for assessing the condition of patients, modern methods of diagnosis and treatment, the correct application of methodological approaches and sets of statistical analysis, methods for solving the problems discussed in the dissertation are based on modern scientific and practical concepts and approaches to the diagnosis and surgical treatment of patients with giant postoperative hernias. Scientific and practical significance of the research results. The results obtained make a significant contribution to the expansion of irradiation of existing ideas about the structure and clinical features of complications of hernioplasty for giant and extensive ventral hernias by identifying the morphological features of the development of a purulent-inflammatory process against the background of the use of alloplastic material, studying predictors of the risk of developing immediate complications, mechanisms for enhancing reparative processes through the use of an improved method of fixing the prosthesis in together using the effect of photodynamic therapy through laser radiation, which made it possible to enhance the antibacterial effect and improve the wound healing process. The practical significance of the study is that, based on the results obtained, the tactical and technical aspects of prosthetic hernioplasty have been optimized, the features of methods of antiseptic exposure and laser stimulation of the wound surface after prosthetic repair have been revealed, enhancing preventive measures for the development of local infection, and the method of surgery for large anterior abdominal hernias has been improved walls, characterized by a combination of factors such as the formation of tension-free prosthetic plasty, preservation of local resorptive function to prevent the development of fluid accumulations, thereby reducing the risk of developing postoperative complications, reducing the frequency of unsatisfactory results, length of hospitalization and the likelihood of relapse. Implementation of research results. According to the results of a scientific study to optimize the tactical and technical aspects of surgical treatment of large and giant postoperative ventral hernias: the “method for plastic surgery of giant hernias of the anterior abdominal wall” has been improved (invention patent No. IAP 2022 0148 dated April 18, 2022). The proposed method of tension-free repair of large hernias of the anterior abdominal wall with strengthening of the aponeurosis with a mesh implant made it possible to reduce the number of complications, shorten the treatment time and reduce the risk of hernia recurrence; the “method for preventing the progression of infection during alloplasty of infected hernias” has been improved (certificate of the Ministry of Health No. 08-32071 dated October 17, 2022). The proposed method made it possible to reduce the frequency of wound purulent-inflammatory complications and shorten the period of rehabilitation of patients after allohernioplasty; methodological recommendations “Tactical and technical aspects of prosthetic repair for large and giant postoperative ventral hernias” have been developed (certificate of the Ministry of Health No. 08-32071 dated October 17, 2022) . The developed recommendations made it possible to optimize the tactical and technical aspects of allohernioplasty in patients with large and giant postoperative ventral hernias; The scientific results obtained were introduced into the practical activities of healthcare, in particular, in the departments of surgery of the Khorezm and Andijan regional multidisciplinary medical centers, the clinic of the Samarkand State Medical University (certificate of the Ministry of Health No. 08-32071 dated October 17, 2022). Improving the tactical and technical aspects of prosthetic repair for postoperative ventral hernias has made it possible to reduce the incidence of specific immediate complications from 40.9% to 15.6%, to reduce rehabilitation time from 8.6±2.7 to 7.1±1.5 days, and also reduce the likelihood of long-term complications from 11.7% to 3.1%. Approbation of research results. The results of this study were discussed at 8 scientific and practical conferences, including 5 international and 3 republican ones. Publication of research results. 26 scientific works have been published on the topic of the dissertation, including 9 journal articles, 4 of which in republican and 5 in foreign journals recommended by the Higher Attestation Commission of the Republic of Uzbekistan for publication of the main scientific results of doctoral dissertations. Structure and scope of the dissertation. The dissertation consists of an introduction, seven chapters, a conclusion, conclusions, practical recommendations and a list of cited literature. The volume of work is 200 pages.
This study conducts a comparative analysis of returns to technology and scale in broiler production across Peninsular Malaysia. Broiler production is a significant component of the poultry industry in Malaysia, and understanding the dynamics of technology adoption and production scale is crucial for sustainable growth and competitiveness. The research employs econometric methods to analyze data collected from broiler farms across different regions of Peninsular Malaysia. By examining the relationship between technology adoption, production scale, and returns, the study aims to provide insights into the factors influencing broiler production efficiency and profitability in the Malaysian context. The findings offer valuable implications for policymakers, farmers, and stakeholders seeking to enhance the productivity and competitiveness of the broiler industry in Peninsular Malaysia.
The article discusses the issues of effective development of the fruit-growing industry from the point of view of the correct choice and formation of types of specialized enterprises engaged in the production and delivery of fruit products to the consumer, and also highlights other factors that determine the effective production of fruits and berries.
Agricultural production is characterized by a high degree of risk, due to the fact that the economy is carried out in open space and there is a high dependence on biological, climatic, and extermal conditions. The inelasticity of the supply of agricultural products in relation to sing changes in market prices, unforeseen situations in the world and changes in the regulatory framework governing agricultural production are significant sources of risk in agriculture
Currently the main roks for agriculture in the world are restrictions on international trade in agricultural products imposed by individual governments, difficulties with Ingistics leading to the interruption of the supply chains hor its final consumers in domestic and foreign markets, agricultural labor within countries due as well as restrictions r on the mobility of to with the quarantine measures in place. The main naks and factors affecting food security are population growth, increasing demand for land, water and energy resources well as dramatic climate change
In conditions of age-related decrease in sex hormones and a number of pathological conditions and diseases in postmenopausal women, there is a deficiency of D hormone. In our country, the geographic location of which is below northern latitude and sufficient ultraviolet radiation, an insufficient content of vitamin D is seen in postmenopausal women. There are a lot of risk factors leading to vitamin D deficiency - the presence of smog and dust in cities, insufficient consumption of vitamin-fortified foods, the presence of problems with the gastrointestinal tract and excretory system and a number of others. One of the important factors that reduce vitamin storage is overweight and obesity, especially in combination with old age, when all absorption processes are reduced. The aim of our research was to study risk factors in women with vitamin D deficiency with subsequent correction of the deficiency state. We examined the level of total 25 (OH) D in the blood serum in 46 postmenopausal women, and identified risk factors. Vitamin D deficiency was detected in 86.96% of women, and its deficiency was registered in 10.87%. At the same time, a pronounced vitamin deficiency was not registered in any patient. Overweight was registered in 32.6%, obesity of varying degrees in 26.1%. Given the indicators, recommendations were given for correcting vitamin D deficiency. All postmenopausal women, especially those with risk factors for deficiency, are recommended to determine the basic level of vitamin D. In case of deficiency, drug correction is recommended to reduce the risk of cardiovascular and oncological diseases.
Among the production of harmful industry all over the world, including in our repub-lic, tobacco production occupies a significant place. In Uzbekistan, tobacco cultivation is car-ried out by workers of the Urgut district of the Samarkand region, which accounts for a large share in agriculture and brings significant economic profit.
The available literature does not cover the issue of the effect of tobacco dust and pes-ticides in combination with uncomfortable microclimatic conditions on the organs and tissues of the oral cavity of tobacco growers.
Some aspects of the mechanism of development of pathological changes in the oral cavity of tobacco growers are not specified in the conditions of Uzbekistan, and accordingly there is no data on adequate methods of their prevention and treatment [1,3]. In this regard, there is a need to study the features of the clinic and the course of the main dental diseases in tobacco growers in order to develop a set of organizational, sanitary, hygienic and therapeutic and preventive measures aimed at improving the quality of the production environment, pre-venting the development and reducing the frequency of dental morbidity among tobacco growers.
Each region of the Fergana Valley is characterized by its strong management centers, the diversity of natural resources, the general agro-climatic factors, the availability and the potential for the creation of a finished product production system. For this reason, it is advisable to work out prospective directions for the deployment and development of productive forces. At the same time, it is important to fully utilize the capabilities of the main sector in the organized economic system of the region. The future development of productive forces in this area is inseparably linked with agro-industrial production and its sectoral and regional improvement. In addition, the interregional production system, which is based on the continuous growth of food production in the regions, the intensification of intersectoral communications, the expansion of the role of intensive factors, in turn, will increase the demand for complex scientific forecasts. At this stage, the scientific forecasting should reflect the activities of the food market and facilitate the expansion of foreign markets. The region's participation in the world economy opens the way for further stages of social and economic development. At the same time, the emphasis should be on the sustainable improvement of the elastic business structure, adapted to the changing competition inherent to the market economy. The main task of the food market in the Ferghana Valley in the near and long-term perspective is to increase production efficiency and bring the level of material welfare of the population to the world's leading countries on the basis of equalizing social and economic development in the regions. This, in its turn, is a very complex and urgent issue, not only with the radical changes in the economy, but also with a change in the lives of the whole society and, consequently, the acceleration of its development. In this regard, this article elaborates the forecasts of the food market in the Ferghana Valley
for 2020-2030 and its alternative scenarios. The first scenario is based on a retrospective analysis of food production in the Ferghana Valley. In the second scenario, the population's food supply is calculated based on the minimum consumer budget, while the third scenario provides the regions' food supply coefficients and supply estimates. On the basis of the analysis of the forecast parameters of the Ferghana Valley Food Market and its results, scientific-practical conclusions have been developed.
Vegetable soybeans are non-traditional crop in the Uzbekistan. The universality of the use of this crop testifies to its potential and value for agriculture, since cultivated soybeans are a food, technical, oilseed, fodder and siderate crop. The article describes the data for the production of high-quality seeds of vegetable soybeans in the conditions of Uzbekistan. It is necessary to comply with the rules of seed production, including individual and group selection in primary seed production and mass selection of elite seed production. It is necessary to select plants with a high yield of beans and well-ripened full-fledged seeds, the selection of beans with pronounced and corresponding to the variety morphological features.
Local duck rearing is an important source of income and food for small-scale farmers in many developing countries. However, the production performance of local ducks is often limited by various constraints that affect their productivity and profitability. This study aimed to assess the production performance of local ducks and identify the constraints of duck rearing at the farmer's level in a selected community in Nigeria. A case study design was employed, including both qualitative and quantitative data collection methods. The study found that local duck production was a profitable enterprise for farmers, but they faced several constraints that limited their productivity, including disease outbreaks, poor nutrition, inadequate housing, and lack of access to credit and markets. The study highlights the need to improve local duck production by providing farmers with access to extension services, credit, and markets and training on best management practices.
Topicality and demand of the subject of dissertation. Various techniques of hybridization arc used in crop breeding, including cotton to produce a wide variability in agronomical valuable traits and develop new forms.
Regardless of its implementation hybridization process leads heredity decoding which allow the new plastic genotypes formation with an ability to change and adapt to the new conditions. Hybridization and selection arc considered as a main synthetic method of new varieties development and a success in this largely depends on the choice of crosses method and genotypes of initial forms. Therefore, there is given a special attention for studying the genetic basis and improving of hybridization methods. However, based on the most widely used of hybridization methods arc not always possible to develop varieties having high parameters of composite agronomical traits. Many developed varieties as a result of breeding methods arc genetically become homogeneous, which leads to a reduction of genetic variation and increasing of risk of cpiphytoty outbreaks and decreasing of total productivity (Boroycvich, 1981). Therefore, it is necessary to increase the genetic variability of crops’ agronomic traits by involving of original forms, as well as wild relatives of crops with genetic resistance to various stress factors, diseases and pests.
In increase cotton production through the creation of early maturing, high-yielding having good fiber yield and quality, resistant to various diseases, pests and stress factors, as well as with low level or toxic gossypol in cotton seeds still remain as critical problem in cotton production.
To overcome these problems there need to improving of genetic basis for assessment of existing donors and through the use of various hybridization methods to create new enriched genotypes, promoting positive recombination of polygene in hybrid’ organism for use in applied cotton breeding. Based on the above stated, the study of the genetic aspects of various methods of remote composite intraspecific and interspecific hybridization, based on the comparative evaluation of the effectiveness in order to isolate valuable recombinants and transgressive forms having new genetic variability of traits arc important both scientific and practical point of view.
The dissertation meets the objectives as set out in the Lows of Uzbekistan «On Seed Production» of December by 21, 2007 and «On Breeding achievements» by August 21, 2002 directed to developing and introduction of high-yielding cotton varieties, with a good yield and fiber quality, tolerance to various factors, as well as improving seed production.
Purpose of researches is comparative study of effectiveness of the various methods of intraspecific composite, convergent and inter-specific (3 to 5 species) hybridization revealing the nature of inheritance, form shaping and transgressive variation of traits, total and (+)-gossypol in creation of genetically enriched breeding material and for using in the applied cotton breeding.
Scientific novelty of the dissertation research is follows:
in the system of topcrosscs there used genetic evaluation for combining ability of main agronomic traits cotton varieties with different origins for further using in intraspecific composite and convergent hybridizations;
there established principally dominant inheritance and overdominance type of inheritance (with deviation toward the initial forms with the high agronomic traits) in F| at composite intra-and interspecific hybridization which genetically distinct accessions from the local and foreign selection and wide transgressive variability in F2-F3, facilitating to efficient selection of valuable recombinants;
first identified the inheritance nature and variability of total and (+)-gossypol in the cotton hybrids’ generative parts, developed by involving of American accessions with high (+)- gossypol and local varieties, as well as their correlation with some agronomical valuable traits;
first there held comparative study of economic traits at the different forms of amphidiploid G.thurheri x G.raimondii K-58 (hirsutum type) and K-59 (type harhadense) for free reproduction and after crossing the cultural forms of G.hirsutum L. species, it was established a wide range of variation of agronomic traits at mutant form of K-59 and composite hybrids, derived from it’s participation as compared to K-58 amphidiploid and it’s composite hybrids. It was found out those two types (type G.hirsutum K-58 and type G.harhadense K-59) of amphidiploid G.thurheri x G.raimondii at the free reproduction exhibits similarities with the both cultural tctraploid species; G.hirsutum L. and G.harhadense L., respectively. When they crossed with the cultivated G.hirsutum L. species these amphidiploid forms also behave as natural tctraploids;
it is revealed that, at the composite hybrids produced with the participation of the both forms of amphidiploid (K-58 and K-59) G.thurheri Tod. x G.raimondii Ulhr., as a result of transgressive variation, there is a disturbance of negative correlations between such traits as yield and fiber length, fineness and boll numbers conducive to positive recombinants emergence and increase donor opportunities of amphidiploids;
by comparative study of different methods of remote intra-and interspecific hybridization revealed the genetic nature of inheritance nature and variation degree of the main agronomic traits in composite hybrids, as well as their effectiveness in allocating recombinants having a new genetic variability of traits;
it is revealed that the possibility of breaking some negatively correlated traits by different methods of composite intra-and interspecific hybridization and selection of recombinants combining early maturity and high productivity, high fiber output with its quality and 1000 seed weight, etc.;
it is confirmed that the effectiveness of used methods such as a composite intraspecific and interspecific crosses, to increase positive transgressive variation and segregation genetically enriched recombinants having new combination of high levels of positive parameters of agronomic traits that were recommended and used to develop valuable initial material and new cotton varieties;
the obtained theoretical data on inheritance nature, hcritability and agronomic traits morphogenesis, levels of total and (+)-gossypol and their correlation with other agronomical valuable traits at developed hybrids could be successfully used in the field of fundamental research, and created unique hybrids, forms, progenies, lines and varieties could be used in applied cotton breeding.
Conclusion
1. There obtained and identified on comparative study base of intraspecific composed and converged hybrids with participation of six registered medium staple cotton cultivars in topcross system and high effects of GCA on the following traits:
«50%-cmcrgcncy-50 % flowering» Yulduz (-0.71); Tashkent-6 (-0.39) and in S-9070 (-0.38); “50% cmcrgcncy-50% maturing” S-9070 (-1.43), and in
Tashkent- 6 (-0.91); one boll weight S-6532 (+ 0.11); 1000 seeds weight S-9070 (+0.51); on productivity Tashkent-6 (+5,28), S-4911 (+4,04) and S-9070 (+2 24); fiber output S-6532 (+1,29); fiber length S-4911 (+0,70) and S-6532 (+0,48); fiber strength S-6532 (+1,57) and S-4911 (+0,91); micronairc S-6532 (+0,24) and Ak-Darya-6 (+0.24). These donors of high valuable traits were used by us for improving of the recurrent varieties by composite and convcrcgcnt hybridization. It was found that involvement of the varieties with a high GCA in convergent hybridization allows improving of the recurrent varieties and developing of a new initial material for cotton breeding:
inheritance nature and variability degree of agronomic traits at intraspecific composite and convergent cotton hybrids revealed the relative efficiency of the studied hybridization techniques during elaboration of new initial material with enriched genotypes of agronomic traits, and recommended to use in geneticselection process;
convergent hybrids F i dominated by early maturity, in terms of productivity and fiber output occurcd overall effect of overdominance, and F2-F3 appeared as positive transgressive forms;
significant effect of the genotype of the parental forms involved in hybridization on the inheritance nature of fiber quality (length, micronairc, strength) had convergent hybrids Fj, as well as their level of recombination in F2-F3 indicating the need for breeding of recombinants on these traits in early generations, taking into account genotype of initial forms;
the inheritance of the wilt tolcrancccs bccamcs not only depending on the pathogen load in soil fungus infections, but also depends on the used hybridization methods. Thus, most high resistance, i.c. negative superdominance on wilt tolerance observed in convergent hybrids F, and F2;
the direction and strength of correlation between the studied traits in intraspecific composite and convergent hybrids varied in depending on crosses type and from genotype of recurrent varieties. At present ease, the greatest number of recombinants with positive combination of high indicator traits which determining fiber quality, as well as its output, length, observed with with composite, particularly with convergent hybridization.
2. For the first time, on the basis of studies on determination the percentage of (+)- gossypol in seeds of genetically different cultivars of Uzbek cotton selection and analysis of variability, inheritance degree of total and (+)-gossypol in the environmentally and genetically remote hybrids and their correlations with economically valuable traits was proved:
the cultivars S-6524, S-6530 and S-6532 which were elaborated involving subspccic of G.ssp.punctatum had the highest level of (+)- gossypol and the «Turon» cultivar which was developed by composite hybridization has a low indicator of the current trait and relatively high level of total gossypol in seeds;
It was determined intermediate inheritance level of (+)- gossypol in the petals and seeds in F| hybrids and wide positive and negative transgressive variability in Ғ2-Ғ3. It was proved that the efficiency of plant selection with high (+)- gossypol in seeds since F2, that confirmed with segregation of constant progenies and lines on trait basis in F4 hybrids;
as a result of research the cross-correlation total and ( +)- gossypol and some agranomically valuable traits was found that between the ( +)- gossypol in the petals and seed exists a weak correlation. The data on correlations of studied traits showed an independent genetic control of (+)-gossypol in the generative organs and independent inheritance of them at cco- geographically and genetically remote hybridization.
3. For the first time, based on comparative study of agronomic traits of amphidiploid G.thurheri Tod. x G.raimondii Ulbr. two forms (hirsitum type -K-58 and harhadense type -K-59) and hybrids derived from G.hirsutum L. varieties revealed:
both studied forms of hirsutum type and harhadense type of amphidiploid G.thurheri Tod. x G.raimondii Ulbr., being functional diploids provided wide combinative variability in the progeny from the free reproduction and crossing with the cultivars of tetrapioid G.hirsutum L., and showed their similarity to G.hirsutum L. and G.harhadense L. tctraploid species, respectively;
as a result of the research a group of unique composite hybrids (F\G.thurherii Tod. x G.raimondii Ulbr.) x G.hirsutum L. confirmed unlimited transgressive variation as the basis of a new form revealing, new gene pool developing for use in applied cotton breeding. Herewith, at bud mutant K-59 observed emergence of phenotypes with higher variability for most agronomic traits compared to K-58;
it was found out that in composite hybrids which obtained by crossing of studied forms of G. thurberi Tod. x G. raimondii Ulbr. amphidiploids (2n=52) and with G.hirsutum L. cultivars were observed relatively rapid improvement on productivity and its components in comparison with freely propagated amphidiploids offspring. Herewith, composite hybrids involving K-58 on boll number in all generations was slower comparied to hybrids derived from K-59;
composite hybrids F, obtained involving two cultivars of cultivated forms on fiber output and length were observed deviation toward the parent with the best expression of the trait. It was revealed that the fiber output and length of the studied composite hybrids susceptible to less variability compared in terms productivity and its components. Relatively high variation was manifested on fiber output in F2, and on fiber length in F2-F3. In freely multiplying offspring of K-59 and its hybrids with varieties in F3 was observed the derivations of more long staple plants compared with hybrids, developed involving K- 58;
free propagating amphidiploids’ offsprings and composite hybrids selected by using of cultural forms showed the least wilt susceptibility compared with the control. Wilt resistance of barbadense type K-59 progenies from the free breeding was higher as compared than offspring of K-58, and higher in composite hybrids F2-F4, obtained involving K-59.
4. Under the general principle of correlation relationships among the studied hybrids were found that composite hybrids F2 amphidiploids’ G.thurberi Tod x G.raimondii Ulbr., both types (K-58 and K-59) with a G.hirsutum L. type Acala sj-5 cultivar showed mainly low positive and negative correlation coefficient values, which in most eases were none significant. In hybrid combination of K-58 x Andijan-60 fiber output and length correlated positively;
5. Based on comparative study of inheritance and variation of agronomic traits in developed 4 genomic [(G.thurberi Tod. X G.raimondii Ulbr.) X G.arhoreum L.] x G.hirsutum L., 5 - genome [(F|K-28 x S-6524 ) x G.harhadense L. hybrids and their backcross hybrids were proved:
the possibility of broad transgress variation and creation genetically enriched recombinants on unique traits;
efficiency of backcrosscs among the composite interspecific earlier generation hybrids for rapid improvement and stabilization of eultuvated forms of cotton;
wide transgress variability presence in 4 and 5 species composite hybrids and their backcross hybrids on productivity and its components starting with F|. In particular, it was confirmed the effectiveness of five species hybridization to increase the boll numbers per plant, boll weight and weight of 1000 seeds at 4 and 5 species and backcrosscs hybridization.
by obtaining recombinants having fiber output 43,1-45,0%, fiber length - 40 mm and above, micronairc of fiber 3.9-4.5 and wilt tolerance it was confirmed the effectiveness of introgressive and transgressive breeding at composite 4-5 species hybridization and their backcross hybrids.
6. As a result of studies of correlations in composite 4-5 species and backcrosscs hybridization of F2 hybrids it was revealed the effectiveness of used methods in interruption of such negatively correlated traits as «fiber output» and «fiber length» from medium positive (r=+0,39) up to high positive (r=+0,62), «fiber length» and «micronairc» -medium positive (r=+0,55), as well as «fiber length» and «fiber strength» -medium positive (r =+0,56 and r=+0.50).
7. Based on intraspecific composite and convergent, eco-geographically and genetically remote and 3-4-5 species and backcrosscs hybridizations were developed the following new breeding progenies, lines and varieties of upland cotton:
by composite and convergent hybridization way-L-7966, L-214/05; CC-896/05; CC-896/28; CC-991/05; CC-991/09; KC-1/05; КС-1/08; КС-1/18; KC-1/35; KC-1/51; KC-1/77, S-231-233/07, L-234-235/07, L-236-237/07, L-242-243/07, L-244-245/07, L-482-483/07, L-484-485/07, L-666-667/07, L-397-398/07, L-802-803/07, L-814-815/07, L-230/05;
cco- geographically and genetically distant hybridization - cultivar S-7300, S-7301, the progenies S-5344, S-5361. HPG-1;
composite 3 - specific hybridization -cultivar «Sulton», «Jarkurgan», S-7276, S-7277, as well as a number of lines;
8. Using the remote intra-and interspecific hybridization it was elaborated unique introgression hybrids, genetically enriched cotton recombinants, progenies, lines, and varieties «Sulton», «Jarkurgan», S-7276, S-7277, S-7300, S-7301 having positive combination of high agronomic traits. Cultivar «Sulton» was included in the State register from 2011 and for the period from 2008 up to 2014 it was sown on the area of over than 275,5 thousand hectares.
9. The following rcccomcndations were given for practize and future studies:
use of method convergent hybridization, allowing improving of agronomic valuable traits of recurrent parent and registered medium staple cotton cultivars and receiving a positive transgressive variability;
as an initial source in convergent crosses use cotton varieties with high General combination ability (GCA) on the following: on early maturity- Tashkent-6 and S-9070; boll weight - S-6532; weight of 1000 seeds S- 9070; on productivity -Tashkent-6, S-4911 and S-9070; fiber output -S-6532; fiber length - S-4911 and S-6532; fiber strength - S-6532 and S-4911; and for micronairc - S-6532 and Ak-Darya-6.
for use as an initial source in cotton genetics and breeding research such new cotton selection progenies as well as the lines: KS-1/05; K.S-1/08; K.S-1/18; KS-1/35; KS-1/51; and KS-1/77, L-7966, L-214/05, S-214/05, SS-896/05; SS-896/28; SS-991/05 and SS-991/09 with early maturity, productivity, wilt tolerance, fiber output and quality.
to use in cotton genetics and breeding researches both USA accessions BC3S,-47-8-l-17, BC3S|-l-3-6-15 with 95% of (+)-gossypol level in seeds and lines HPG-1 and others with 90% of (+)-gossypol level, as donors on this trait. Since 2012, developed and studied in the competitive variety testing of Institute the following lines: L-404-05 and L-6970 with high (+)- gossypol level were recommended for testing on ground control of the State Inspection Commission for Agriculture crops variety testing.
widespread use of various forms of synthetic tetrapioids G.thurheri Tod. x G.raimondii Ulbr., 4-5 species composite hybrids [(G. thurheri Tod. x G. raimondii Ulbr.) x G.arhoreum L.] x G.hirsutum L. and [(F t K- 28 x C-6524 ) x G.harhadense L., as well as their backcrosscs for achievement the broad transgress variation, elaboration genetically enriched recombinants on economically valuable traits and their use in practical cotton breeding;
to extend the areas in of early maturing commercialised cotton cultivar «Sulton» and perspective one «Jarkurgan» as well broad testing of such as new varieties S-7277, S-7300 and S-7301 in the republic.