The visual organ injuries in diabetes mellltus are an urgent problem-of ophthalmology to investigate. However, in our»Republic the studies of this kind are infriquent and do not use epidemiologic approach. Six hundred patients with diabetes mellltus of types I and II were examined, they being the residents of Tashkent and our examination revealed the visual organ changes. The eye fundus was injured in 83.68% of patients with dieletes. type I and in 84.53% of those with type II, the extent of the eye fundus injury being greater in IDDM (Insulin Dependent Diabetes Mellltus) than in IIDM ( Insulin Independent Diabetes Mellltus). The clinical analysis showed that the frequency of the lens clouding in patients with diabetes mellltus increased with the .age of the patients, duration of the disease and its severity. Me had developed the classification of the injuries of the eve fundus in patients with diatetes mellltus which-allows to choose the proper tactics of treatment and succession of specialists and measures at various stages of the treatment course. The integral assessment of the risk factors of diabetic retinopathy revealed that the risk factors in IDDM and IIDM are similar,but their influence on development of the disease is different. To improve prophylaxis of the retina injuries in patients with dia-betes mellltus-, we selected the following risk groups: "favourable prognosis", "attention", and " unfavourable prognosis". We also developed the criteria of time and frequency of examination of patients in these groups. The analysts of dynamics of morbidity rate for diabetes melli- tus by 2005 showed the further increase of this rate - in 1.4 times. Blindness in patients with I DOU is 5.65% and in those with IIDM - 11.11%. On the basis of the material described above, the neccessery conditions for organising the ophthalmo-diabetic service were formulated.
Efficiency of quadropril preparation was tested in 47 patients with types I and П diabetes mellitus with vascular complications. Functional condition of the kidneys, hemodynamic indices and eye bulbar conjunctiva microcirculation were assessed. The preparation had marked hypotensive effect, improved glomerular nitration, influencing insulin resistance, contributed to considerable decreasing microcirculation and lacked side-effects.
Актуальность обуславливается тем, что в последние дни увеличилось число людей, страдающих сахарным диабетом, а также возникли большие возрастные отличия, которые колеблются. Также заметны разные патологии влияющие на протекание беременности и его исход.
At the beginning of the third millennium, for mankind, which overcame the epidemic of life-threatening infections during its centuries-old history, the problem of cardiovascular diseases (CVD) came to the fore in relevance among all causes of morbidity and mortality. A significant role in this was played by lifestyle modification associated with limiting physical activity, increasing the calorie content of food, and a steady increase in emotional stress. All of this potentiates the main risk factors for CVD, which are a “negative asset of progress,” namely increased blood pressure (BP), dyslipidemia, diabetes mellitus (DM) and obesity. Since 1988, after G. Reaven's Banting lecture, it is customary to designate the interconnected combination of these pathologies by the single term "metabolic syndrome X".
Метаболический синдром является чрезвычайно актуальной проблемой современной медицины. Эксперты ВОЗ определяют метаболический синдром как новую пандемию века, охватывающую экономически развитые страны. Метаболический синдром широко распространен в популяции (около 20%).
Violation of the kidney filtration function is common enough among patients with cardiovascular disease (CVD), especially against disorders of carbohydrate metabolism (IGM). Renal dysfunction (PD) is associated with more frequent development of cardiovascular complications. In turn, the probability of development of renal disease in patients with cardiovascular disease is significantly higher than in general population. This bidirectional pathogenetic mechanisms existing between cardiovascular and kidney diseases were the basis for the formation of cardiorenal syndrome concept. The review discusses the general parts of pathogenesis within the cardiovascular continuum. In addition, it shows the effect on metabolic disorders during CVD combined with renal dysfunction. The review reveals a recent view on the main mechanisms of cardiorenal syndrome.
This article provides summary recommendations of some manuscripts related to Covid-19 and diabetes mellitus comorbidity. Manuscripts related to this topic were searched in PubMed. The article describes the mechanisms how COVID-19 may enhance complications in individuals with diabetes mellitus and providing special considerations on anti-diabetes drugs commonly used in patients with type 2 diabetes in view of COVID-19 developed by group of researches. These recommendations can be useful for those physicians who are involved in case management of Covid-19 and diabetes mellitus.
The present study reports for the first time the genotypic distribution of PPARG Pro12Ala polymorphism in group of Uzbek athletes. The human peroxisome proliferator-activated receptor gamma (PPARγ) is involved in lipid storage, glucose homeostasis and adipocyte differentiation. Pro-allele contributes to the development of high physical performance in sports where you need extra physical stamina, and Ala-allele - in sports based on the strength and speed. An analysis of the distribution frequency of genotypes of the PPARG gene, based on the general model of inheritance, in the group of athletes involved in football, was statistically significant compare to control (p =0.004). These results suggest that the presence of PPARG Ala allele, which increases the sensitivity of muscle tissue to insulin, and thus enhancing its anabolic effect on skeletal muscle, predisposes the development and display of speed-power qualities. In addition, we are studied frequencies of Pro/Ala genotypes in Uzbek population in comparison with Russian, Ukrainian, Italian, Bosnian and Herzegovinian, and Ethiopian samples. In conclusion, the present data seem to suggest that some selective factors such as climate could have influenced the present distribution of the Ala allele.
Essential hypertension can be defines as rise in blood pressure of unknown cause. It usually clusters with other risk factors such as ageing, weight gain, insulin resistance, diabetes and hyperlipidemia. Hypertension is common in developing countries, especially in urban area with sedentary lifestyle and low awareness, treatment and control. Though hypertension as a disease is not described in classical Ayurveda texts, there are many theories which can be adopted to treat. Data of four patients diagnosed with hypertension visiting OPD of Ayushakti Ayurveda Pvt Ltd were recruited for the study and the data of the same is analyzed in this case report.
This present study shows that this approach when administered in Hypertensive patients, they were able to significantly decrease the systolic as well as diastolic blood pressure without any toxic- or side effect. We were able to minimize the dose of antihypertensive modern molecules gradually when these polyherbal formulations were used along with Shirodhara and Heartdhara. With the help of this Ayurveda protocol hypertensive patients can be treated successfully by providing strength to the heart muscles.
The continuous development of medicine, which is an integral part of human life, allows to constantly replenish the terminological layer of the lexicon by introducing new names and developing stable ones. The fact that terminology in various disciplines exceeds the number of words in common use makes it necessary to study special vocabulary. In particular, severe acute respiratory syndrome, caused by 2 (SARC-CoV-2) detected in China on November 17, 2019, a new infectious disease COVID - 19 coronavirus infection, has now led to a pandemic situation worldwide. This reaffirms that an in-depth study of medical terminology is one of the most pressing issues. In this article, the features of the construction of Chinese medical terms; we have identified suffixes, semi-suffixes, prefixes, and semi-prefixes that are most actively involved in word formation, affixation methods, and term formation. It was considered that terms borrowed from other languages also played an important role in the Chinese medical lexicon. Terms learned from other languages also play an important role in the medical lexicon of Chinese; a pure phonetic assimilation is often found in the names of these substances 夫 南西林 [fūnánxīlīn ] “furatsilin" , many of which have a semantically assimilated alternative 因素林 [yīnsùlín] "insulin", some of them 阿摩西林 [āmóxīlín] and 阿莫西林 [āmòxīlín ] “amoxicillin” have been considered. Abbreviated complex words make it difficult to understand medical texts because they are formed in different ways, so abbreviations in Chinese 脱氧核糖核酸 [Tuōyǎng hétáng hésuān] "deoxyribonucleic acid" = 脱氧核 酸 [Tuōyǎng hésuān] «DNA»), that is, the abbreviations were studied separately. During the study of the construction of medical terms, we found that most terms and terminological phrases are formed by the method of addition and affixation. Systematization of these allows to determine the methodological basis for the translation of new terms in Chinese. In the article it has been investigated and drawn relevant conclusions on the subject of the works of Russian and Uzbek linguists such as Karimov A.A, Gorelov V.I. ,. Popova D.E., Xorechko U.V., Frolova O.P.,Ochirov O.R, Superanskaya, AV, Superanskaya, A.V, Karimov A.A, Nosirova S.A, Hashimova S.A, Mustafaeva S.