Congenital heart defects are considered an urgent problem in pediatric cardiology. If high-quality medical care is not provided on time, about 50% of children with cardiovascular diseases die in the neonatal period, and 25% die in the first year of life.
Early diagnosis of Myeloproliferative diseases (MPD) is one of the serious problems of oncohematological practice. MPD efers to multifactorial diseases, the development of which is influenced by both environmental factors and genetic predisposition. The study studied the association of the carriage of the genotype for the polymorphic marker encoding glycoprotein-P and the development of MPD. The homozygous T / T genotype of the rs1045642 polymorphism of the MDR1 gene is a significant determinant of the increased risk of developing MPD in Uzbekistan (P<0.05). Conclusion. Genotype association the rs1045642 polymorphism of the MDR1 gene is associated with the risk of developing MPD.
The review article provides up-to-date information about the etiology, pathogenesis, classification, clinical picture and diagnosis of the disease. The issues of drug treatment of reactive arthritis are covered.
Treatment of women with a combined form of fibroids and adenomyosis is much more complicated than each disease separately. Infertility is acommon cause of treatment in these patients. The purpose of this study was to determine the tactics of treatment of women with a combinedform of fibroids and adenomyosis. We examined 65 women with menstrual disorders. All examined were divided into 3 groups: group 1 - 55women with a combined form of fibroids and adenomyosis, group 2 - 40 women with adenomyosis, group 3 - 40 women with uterine myoma.
The article is about the creativity of poets who lived in Golkonda in the 17th century during the reign of the Kutubshah dynasty, such as Mulla Gavasi and about his book Sharkhi Margub al-Kulub and Shahadat al-hakika, Mulla Vajahi, about his masnavi "Irshadnama”.