Analysis of the assortment of sedatives registered in the Republic of Uzbekistan showed that sedatives are represented on the pharmaceutical market of the country by such dosage forms as drops, solutions, tinctures, syrups, medicinal herbal raw materials, capsules and tablets. Considering that sedatives registered in the form of a substance, with the exception of the dry extract of Leoglycyrfl produced by “Uzkimyofarm”, there are practically no names of S.K. Islambekov in the Joint Stock Company. In this regard, we consider it expedient to create a new sedative medicinal product of herbal origin in the form of a substance and obtain dosage forms based on it.
The article analyses arbitration as a means of resolving international disputes. The author states that the development of arbitration in the world created strong international and regional arbitral institutions that allow parties to choose a forum according to their needs and resolve disputes in the way, which suits them more. In conclusion, the author comes to the opinion that nation-states must further remove obstacles to international arbitration by, inter alia, joining various international treaties and ensuring that effective mechanisms exist to enforce international arbitral awards to improve the investment climate.
Синдром слабости синусового узла (СССУ) клинико-электрокардиографический синдром, отражающий структурные повреждения синусового узла, его неспособность выполнять функции водителя ритма и обеспечить проведение импульса к
предсердиям
In this article, special attention is paid to the explanatory dictionary of scientific, popular scientific terms intended for use by various categories of readers, regardless of whether it relates to a certain sector of the economy or not.
Annotation. This article shows a method for solving two periodic solutions of second order differential equations with piecewise continuous constant arguments in the form x''(t)+px''(t-1)=qx([t])+f(t ), where [.]denotes the function of the largest integer, p and q are non-zero real numbers, and f(t) is a real-valued periodic function. In the article, firstly, the conditions for the existence of 2-periodic solutions of second-order differential equations are given, and then the solution of the problem is represented as a linear system of algebraic equations
The article discusses the author's corps and its significance in modern glossary, the world of Pushkin's author's corps, the Czech writer's corps, Shakespeare's author's corps and their shortcomings. The interface of the author's corps is made up of different designs and structures, and the author is responsible for its completeness, the interface should be attractive and impressive. The creation of the interface is based on the design of the national or modern features, the interface should involve the life and works of the artist in photoes. The Corpus of Linguistics is a very rapidly developing branch of the world of computational linguistics, which has achieved great success in this regard.
The Corpus of Linguistics is also taught as a science in world universities. The subject of this discipline is the theory and practice of building a corpus, such as body features and the basics of programming. The Corpus of Linguistics deals with general theory and practice of computational linguistics, the formation of the language body, and computer technologies. The article tells about modern information technologies that have created tremendous opportunities for language functionality. Computer translation, editing, analysis, electronic dictionary and thesaurus are proof of our opinion. Especially the creation of modern electronic dictionaries and the culture of their use is one of the effective ways of learning a language. In particular, the role of language buildings created and developing at a fast pace throughout the world when demonstrating the ability and ability to master the language is very large. The purpose of the article is to study the linguistic foundations of the Uzbek language corpus, to study the linguistic value of the linguistic corpus, the history of corpus linguistics, to study the author's linguistics of the corpuses, its features in the social, lexicological, educational and other fields.
The article gives an idea about the interface, the content of the corpus, its flawless functioning and at first glance the importance of the author’s personality, creative heritage, classification.
Понимание остеоартрита (ОА) как болезни, прежде всего, суставного хряща ушло в прошлое. Согласно современным представлениям, ОА – это заболевание суставов, характеризующееся клеточным стрессом и деградацией экстрацеллюлярного матрикса, возникающими при макроили микро-повреждениях, которые активируют ненормальные адаптивные восстановительные ответы, включая провоспалительные пути иммунной системы. В связи с этим становится понятным, почему ОА рассматривается как органное поражение, т. е. заболевание всего сустава, при котором в процесс вовлекаются хрящ, субхондральная кость, синовиальная оболочка, связки, капсула, мышцы. ОА – самое частое заболевание суставов, которым страдает более 10% населения земного шара [1–3]; 81 млн больных ОА зарегистрирован в пяти развитых странах (Германия Италия, Франция, Велико-британия, Испания) и более 380 млн – в России, Бразилии, Индии и Китае [4]. По данным официальной статистики, с 2000 по 2010 г. в Российской Федерации число больных ОА увеличилось почти 2,5 раза [5]. Каждый год диагноз впервые устанавливается более чем у 600 тыс. пациентов, но и эти данные не отражают истиннойраспространенности заболевания, поскольку не все пациенты обращаются за помощью в лечебные учреждения. В недавно проведенном эпидемиологическом исследовании было показано, что в России ОА коленных и (или) тазо-бедренных суставов страдает 13% населения старше 18 лет [6].
В настоящее время нарушения нормофлоры(дисбактериоз), состояние иммунного статуса и проявления болезни рассматриваются в единстве, причём роль пускового механизма в каждом конкретном случае может принадлежать любому из компонентов этой триады: дисбактериозу, иммунному статусу и патологическому процессу. [2,4]. Инфекционные факторы играют роль в возникновении многих ревматических болезней. Кишечные бактерии и продукты их жизнедеятельности могут стимулировать развитие артрита с поражением различных областей [1]. При этом значительно повышается проницаемость кишечной стенки для микробных антигенов и их токсинов, что рассматривается как важнейший фактор сенсибилизации организма к микробным антигенам и, возможно, развитию аутоиммунных заболеваний, в том числе артритов [5]. К возникновению артритов могут иметь отношение различные микроорганизмы, обладающие неспецифическим воздействием на иммунную систему, нарушения со стороны которой определяют дальнейшее течение болезни [3].
This article presents the results of a study of the hepatoprotective properties of the herbal drug darmonal in combination with phytin compounds in experimental animals (rats) with experimental hepatitis caused by SS14 intoxication. The obtained research results showed that darmonal in combination with phytin compounds increases the synthesis of total protein and normalizes the composition of protein fractions of blood serum. Both studied drugs have a high level of hepatotropic effect. The combination of darmonal and fitin-C was the most effective. According to this effect, they were superior to the hepatoprotective drug LIV-52.
The article is devoted to a review of the topical problem of our time “Microbiocenosis of open cavities of the body and its role in the occurrence of many diseases of the human body ”. It has now been proven that the normal microflora of the human body plays a huge role in the normal course of life processes. The slightest violation of the composition of microorganisms leads to various irreversible defects in the normal course of human life, which are associated with the functions of the microbiocenosis and which no medicine can replace. The concept of microbiocenosis appeared in the 70s of the last century, although the first stone in this direction was put by Louis Pasteur, who proved the role of a microorganism in the process of fermentation and digestion. Many scientists contributed to the leap forward development of this science, which was forced due to errors in the use of antibiotics and chemotherapeutic drugs. Yes, indeed, the path of development of the science of biocenoses is closely related to the misuse of drugs, which often leads to dysbiosis. In addition, environmental pollution due to the uncontrollable development of urbanization plays a huge role in the development of dysbiotic processes.Therefore, with the aim of acquainting readers with the concept of biocenoses, certain pathways of pathogenetic links in the development of various diseases in violation of the composition of the normal microflora of the human body, we set ourselves the task of conducting a partial review of the achievement of the science of biocenoses of open cavities of the body.