Целью этого национального исследования было определение распространенности кариеса, опыта кариеса и индекса значительного кариеса (SiC) у 12-летних детей в Узбекистане.
Dental implantation is currently one of the most promising areas in the rehabilitation of dental patients. Despite the success achieved, dental implantation, like other surgical methods of treatment, is accompanied by various kinds of complications. The most common complications are of an inflammatory nature. However, there are many problems in dental implantology. This article presents a review of the scientific literature on risk factors for early and late complications of dental implantation. It is considered that a well-established and integrated dental implant should function for at least 10 years, satisfy the patient in aesthetic and functional terms, have clinical stability, and be biocompatible with respect to the surrounding tissues.
The tutorial provides brief information about various implant systems, their advantages and disadvantages, methods of surgical intervention, mechanisms for integrating implants in tissues. Modern views on the mechanisms of reparative bone regeneration, the structure and main characteristics of bone tissue are briefly presented. Describes possible complications of odontoplasty, techniques of their elimination and prevention. Biomechanical principles of orthopedic treatment of dental defects using implants are considered. The manual is prepared in accordance with the training program for specialists in the discipline "Surgical dentistry". The textbook contains the main questions of dental implantology. It at the present level presents the fundamental topics of dental implantology including osseointegration, of the morphological basis of dental implantation. Indications, contraindications, planning and surgical stages of installing plate and screw implants, complications arising during and after dental implantation, as well as their prevention and treatment are described in detail. The tutorial contains test tasks and situational tasks for monitoring the development of knowledge with reference standards of answers, as well as illustrative materials. The text of the manual contains illustrative material, final questions for each of the sections.
The feasibility and effectiveness of complex treatment in patients with secondary adentia and past Covid-19 was assessed. The planning of dental implantation in patients who have undergone Cavid-19 should be carried out with the most complete use of diagnostic procedures, including clinical, laboratory and functional examination of the patient. A systematic analysis of the studies conducted at all stages of dental treatment allows us to conclude that there are relative contraindications to dental implantation in patients with underlying pathology and who have undergone Cavid-19.
The popularity of orthopedic treatment using the method of dental implantation causes the interest of researchers to study the integration of implants in bone tissue. Analysis of the literature shows that the improvement of research technology and interdisciplinary approach to the study of the phenomenon of osteointegration of dental implants has led to a change in traditional concept in recent years. This article summarizes information about the physiological processes and cellular interactions occurring on the border "implant-bone tissue" in various stages of integration. The results of studies indicate the need for revision notions of bio inertness of titanium implants and consideration of the integration process in the immunological aspect.
The tutorial provides brief information about various implant systems, their advantages and disadvantages, methods of surgical intervention, mechanisms for integrating implants in tissues. Modern views on the mechanisms of reparative bone regeneration, the structure and main characteristics of bone tissue are briefly presented. Describes possible complications of odontoplasty, techniques of their elimination and prevention. Biomechanical principles of orthopedic treatment of dental defects using implants are considered. The manual is prepared in accordance with the training program for specialists in the discipline "Surgical dentistry". The textbook contains the main questions of dental implantology. It at the present level presents the fundamental topics of dental implantology including osseointegration, of the morphological basis of dental implantation. Indications, contraindications, planning and surgical stages of installing plate and screw implants, complications arising during and after dental implantation, as well as their prevention and treatment are described in detail. The tutorial contains test tasks and situational tasks for monitoring the development of knowledge with reference standards of answers, as well as illustrative materials. The text of the manual contains illustrative material, final questions for each of the sections.
Dental implantation is currently one of the most promising areas in the rehabilitation of dental patients. Despite the success achieved, dental implantation, like other surgical methods of treatment, is accompanied by various kinds of complications. The most common complications are of an inflammatory nature. However, there are many problems in dental implantology. This article presents a review of the scientific literature on risk factors for early and late complications of dental implantation. It is considered that a well-established and integrated dental implant should function for at least 10 years, satisfy the patient in aesthetic and functional terms, have clinical stability, and be biocompatible with respect to the surrounding tissues.
В последние несколько месяцев 2022 года число заболевших острыми респираторными инфекциями (ОРИ) детей значительно выросло. В этот период все койки в ДГКБ св. Владимира были перепрофилированы для работы с пациентами с диагнозом ОРИ. На основании данных ПЦР диагностики (мазок из носоглотки), проводившейся всем поступающим в ДКГБ св. Владимира детям, в большом числе случаев стало возможным
установить этиологическую природу заболевания.
According to the Protocol of intraoperative direct prosthetics (IDP), the immediate functional load is provided by temporary orthopedic structures. The Protocol significantly reduces the treatment time and the need for preliminary pre-prosthetic reconstructive surgery-bone transplantation methods and allows you to bypass areas where transplants are ineffective. The orthopedic Protocol is simplified as much as possible. The possibility of prosthetics without the use of cement fixation of prostheses is realized. Protocols of intraoperative direct prosthetics for implant-prosthetic rehabilitation of patients require prototyping and designing of treatment results.
Topicality and demand of the subject of dissertation. Bronchial asthma (BA) is one of the most common and serious diseases, which in the world suffer from 3 to 12% of the child population of the globe. Proportion of adolescents with asthma, is one third of all children with this disease. High prevalence of asthma in the numbers of teenagers, characteristics of the disease, age-related aspects of the functioning of the endocrine and immune systems of teenagers that cause difficulties which arise in the course of the diagnostic process, highlight the need to find innovative approaches to diagnosis and treatment of this disease.
It is known that the key immune mechanisms in the pathogenesis of the vast majority of AD cases is real and indisputable fact. Currently, considerable interest to researchers involved in the pathogenesis of positions of allergic diseases, especially asthma, along with IL-4 and IL-13 causes a number of other (IL-6, IL-8, IL-10, IL-5, INF-a and INF-y) immunoregulatory cytokines.
Genetic predisposition plays an important role in the development of allergic diseases. Currently available data on the relationship with asthma and associated with disease symptoms polymorphism approximately 150 genes. Important role as the main contender for the predisposition to asthma gene is a gene encoding flchain of high affinity receptor IgE. Interaction elevated levels of antigen-specific IgE with FceRip plays a central role in the pathogenesis of allergic asthma. Particularly attractive candidate gene asthma is also one of the enzyme genes biotransformation - GSTirl, encoding glutathione S-transferase and л1 express almost exclusively in the pulmonary tissue. This gene is located at the locus 11 ql 3, for which repeatedly shown clutch with atopic symptoms. Accumulated in the literature say about the relationship of gene polymorphism FceRI, GSTnl with different allergic diseases.
From this perspective, the study of immunological and genetic mechanisms of the pathogenesis of this disease for the construction of rational treatment and prevention emphasizes the relevance of this thesis research.
From the earliest days of independence, the country has successfully implemented state programs aimed at reforming the health care system. As a result, the targeted implementation of organizational health and research activities aimed at effective diagnosis, prevention and treatment of asthma among adolescents, with some success in the treatment of this disease in the country. However, now the problem of early diagnosis and the development of effective programs for treatment and prevention among adolescents with asthma remain one of the most important issues of modern health care. This research work was carried out in the framework of the tasks set by the Resolution of the Cabinet of Ministers of the Republic of Uzbekistan "On additional measures to improve the health of women and the younger generation," dated 25.01.2002 for the №32. In this regard, the need to deepen the information received about the state of cellular and humoral immunity among adolescents, asking pathogenetic informative immunogcnctic studies in asthma arc one of the important criteria demand the dissertation topic.
Purpose of research is study the immunological and genetic mechanisms of the pathogenesis of asthma in adolescents and form the basis of this plan rational diagnostic and therapeutic measures in this pathology.
In To achieve this goal the following tasks of research is solved:
to establish the clinical course of asthma in the population of adolescents living in the Samarkand region, in the early stages of the pathological process in the bronchopulmonary system.
explore the features of the state of cellular and humoral immunity, as well as activation markers in asthma in adolescence by determining the immunophenotype of lymphocytes in the peripheral blood.
to examine the level of production of immunorcgulatory cytokine interleukin-6 and interfcron-y and install them pathogenetic informative in asthma among adolescents.
to determine the features of distribution of allele and genotype frequencies of polymorphic variants of genes and FceRip GSTnl population Uzbek people with asthma, compared with the healthy part of the population.
examine the clinical and immunological aspects effectiveness of therapies using drugs and polioksidony tsikloferon in patients with asthma in adolescence.
on the basis of studies to develop a multivariate model of formation of bronchial asthma and develop an optimal algorithm for the diagnosis, treatment, prevention in adolescents with this pathological condition.
Scientific novelty of dissertational research consists in the following:
proposed introduction to the work of doctors teen clinics layered approach testing can significantly improve the detection rate of asthma in adolescence and optimize treatment and preventive measures in high-risk groups;
first defined the peculiar characteristics of the quantitative parameters of the immune status of patients with asthma in the cohort of adolescence and the corresponding proposed regulations and guidance documents for the healthy part of the adolescent population;
for the first time presents a comprehensive assessment of the cytokine profile of blood serum in bronchial asthma in adolescents. Specific features of products immunorcgulatory cytokines IL-6 and INF-y and their pathogenetic and regulatory information content in asthma among adolescents;
first analyzed the distribution of alleles and genotypes of polymorphic gene variants and gene FceRip GSTirl among patients with different phenotypic variants of AD and healthy individuals of Uzbek nationality, which resulted in the identified markers of increased risk or, conversely, resistance to the development of asthma in adolescents Uzbek ethnicity;
algorithms for phase diagnosis, treatment and prevention of asthma in adolescence in terms of disclosure of important moments of the pathogenesis of the disease, allowing to build a rational sequence of diagnostic search, aimed at verifying the diagnosis and expedient construction of preventive measures.
Conclusion
1. Set the frequency of occurrence of the disease and the structure of "asthma" in the arid zone among teens. Said pathology is recorded in 9,6% of the population surveyed adolescents, while the disease is more common among females. In the structure of the disease prevails periodical exposure and mild persistent form.
2. Identified by clinical features of asthma among adolescents living in the arid zone, indicate a high frequency of lesions of the bronchial tree association with allergic processes in other organs and tissues: in 73,9% of the AR, 53,7% with AK. 16,6% with BA and 14% with urticaria/angiocdcma.
3. Found that in the study population of patients with asthma adolescence occur expressed disturbances of the immune status, manifested deficit indicators as cell (CD3‘, CD4+, CD8 , CD16+), and humoral immunity (CD19 , IgA, IgG, IgM) and activation markers (CD23+, CD95). The immune status of patients with asthma in young people, adolescence has distinctive features, the depth of detected violations immunoreactivity was most pronounced in the younger age group.
4. In patients with bronchial asthma in adolescence revealed distinct changes in cell-cell interactions in the immune system: a significant increase in the content of Th2-cclls secreted IL-6 is a regulator of maturation of antibodies and immunoglobulin production itself, and vice versa reducing regulator activity of Th 1-cell cytokine INF-y.
5. It was found that the contents of cytokines IL-6, INF-y and in the peripheral blood is in communication with one pathogenic disease. It is shown that the lowest level of INF-y production in the scrum is characteristic of allergic clinical pathogenic variant asthma in adolescence. Adolescents suffering from predominantly infectious form of asthma, there is a sharp trend towards increased production of IL-6 in peripheral blood.
6. Revealed that markers of increased risk of allergic forms of asthma in adolescents Uzbek ethnicity arc genotype FceRip-109T/T allele FceRip-109T, low-risk markers - FcsRip-109C/C and allele Fc£Rip-109C. A high degree of cohesion genotype FcsRip-109T/T allele and FcsRip-109T with hereditary burden of asthma in the Uzbek population.
7. Among females ethnic Uzbek Association revealed lie-105 allele and genotype Ilc-105/Ilc-105 polymorphic gene locus GSTkI at high risk for asthma. Revealed that the genotype associated with the development Ilc-105/Ilc-105 allergic form of asthma in adolescents Uzbek population.
8. Complex therapy with adolescents’ patients with asthma ciklofcron and polyoxidonium, providing immunocorrective effect, enhances the clinical efficacy of basic therapy. In the study of prophylactic efficacy of immunomodulators positive indicators prevailed in the group of patients receiving polioksidony, necessitating its inclusion in the priority scheme of integrated treatment and prevention of asthma in adolescents.
The rural population, in comparison with the urban population, has even fewer opportunities to receive dental care, since dental institutions, where the most qualified personnel and the latest equipment are concentrated, are located mainly in cities. Diversity of geographical and economic conditions of rural population, state of communications, accessibility of transport, etc. they aggravate the inequality of residents of different localities in the possibilities of obtaining dental care, so the specifics of the forms and methods of its provision in rural areas is primarily in the approximation of General dental care to the entire rural population.
Dental membrane-a special film that is used in dental practice as a barrier and fixing material in procedures for dental implants. The use of the membrane can successfully fight bone atrophy, preventing its loss, which in turn creates favorable conditions for dental implants.
This article considers that the study of dental anxiety in relation to demographic indicators before patients visit the dentist is necessary for the study. This study examined demographic indicators (age, gender) and dental visiting habits of patients using a questionnaire method.
The purpose of this study was to determine how dental anxiety, demographic factors, and the nature of dental visits are interrelated. This cross-sectional study involved 100 patients who independently completed a questionnaire that included a modified indicator of dental anxiety (MDAS). In addition, demographic information was collected. According to regression analysis (p<05), anxiety about dental problems leads to improper dental treatment. According to the latest analysis, children between the ages of 9 and 15 and those who have never seen a professional dentist are more likely to experience dental anxiety. Boys are more likely than girls to experience anxiety about their teeth. With age, anxiety about teeth decreases. Poor oral hygiene is caused by high dental anxiety, and dental anxiety is increased in people who have never visited a dentist. The results of this study have implications for oral health and can be applied in healthcare programs to improve the effectiveness of care.
In the structure of dental disease parodontal disease occupy second place after dental caries. Therefore, the study of the epidemiology of this pathology and its appeal to the adult population continues to be relevant. At the same time, the question of the peculiarities of the appeal of the population of certain age and sex groups, ethnic groups, including national characteristics and living conditions in different regions of the country remains unexplored.
In the structure of dental disease parodontal disease occupy second place after dental caries. Therefore, the study of the epidemiology of this pathology and its appeal to the adult population continues to be relevant. At the same time, the question of the peculiarities of the appeal of the population of certain age and sex groups, ethnic groups, including national characteristics and living conditions in different regions of the country remains unexplored.
In recent years, research has been carried out to study the problems of improving the organization of dental care for both the General population and individual categories of industrial workers4,6.
However, to date not carried out in-depth studies on the problems of improvement of dental care to employees of the chemical industry in the new socio-economic conditions of development of industrial complex and reform of the health system, there is no comprehensive study of the current status of dental service medical-sanitary unit (MSCH) large enterprises, comparison of availability and quality of dental care to employees at the place of residence and place of work.
The purpose of this review is to study the dental morbidity of chemical workers, develop measures to improve their dental health and improve the quality of life.
At the present stage of development of the industrial complex of our country, a number of large enterprises have the opportunity to organize dental care for employees, primarily with harmful working conditions, at a higher level. At the same time, the implementation of the preventive orientation in dental care for the working population remains an unsolved problem2,3.
The successful functioning of any medical service in modern conditions is possible only with the optimal interaction of all parts, all elements of the health system depends largely on the level of organization and management of medical institutions to optimize their work7,8.
Keywords: Condition of the mucous membrane of the oral cavity, the hard tissues of teeth and paradontium, taste analyzer, unfavorable factors of production.
Material And Methods Of Research: It is planned to conduct a study of 120 workers of JSC "samarkandkime" - the main group, as well as 115 patients who applied to polyclinic No. 10 and are not related to the chemical industry - the control group.
The data that was received was subjected to statistical processing using the Microsoft Excel application package. The reliability of the difference in parameters was determined by the student's criterion.
Results and discussion.Currently, the issues of dental health for workers in various industries are relevant.
Various harmful factors of production can have a negative impact on human health, including on the tissues of the teeth, periodontal, oral and lip mucosa.
The development and implementation of new therapeutic measures in the field of dentistry as a level of work on "Reform of the medical field and the application of modern technologies and methods of treatment" is a pressing issue today. Nowadays, prosthetics of secondary adenomas present in the upper and lower jaws are one of the current problems facing dentists. One of the modern ways to overcome this problem i.e. dental floss defects is dental implantology.