The aim of the investigation was to study the pathomorphological changes in the structures of the myocardium in dilated cardiomyopathy (DCM). We obtained autopsy materials for DCM cases at the Republican Center for Pathological Anatomy over the past 20 years (2010 2020), and also analyzed the autopsy protocols and medical history. Sudden development of heart failure of the right and left ventricles with DCM, cardialgia and angina pectoris; In some cases, with thromboembolism, cardiac arrhythmias were observed, often accompanied by ventricular fibrillation, ventricular extrasystoles and blockade of conduction. Histologically, the following types of pathological changes were observed in the myocardium and endocardium with DCM: excessive proliferation of interstitial connective tissue, the development of myxamatosis, and sometimes lipomatosis. The main changes characteristic of DKMP were muscle fiber dilatation, that is, thinning of muscle fibers, thinning, fragmentation and homogenization of cardiomyocytcs, disordered arrangement of nuclei, and deformation and degeneration due to changes in the environment.
This paper examines the level of electron microscopy of structural changes that develop in the myocardium as a result of dilated cardiomyopathy (DK.MP). A patient myocardial fragment from DKMP was prepared in a specific order for electron microscopy. The results show that DKMP cardiac-myocardial infarction is manifested by destructive changes in the circulatory and connective tissue, circulatory, edema, dystrophy, destruction submicroscopic structures. Dystrophy, atrophy, and destruction of organelles in the sarcoplasm of cardiomyocytcs led to the destruction of all organelles, including mitochondrial ultrastructure shrinkage, deformation and disintegration of crystals, vacuolation of the matrix, lipidization, and deposition of calcium salts. Myofibrils are characterized by deformation, tearing of sarcomeres, disordered arrangement of actin and myosin structures, separation from each other, in one of which only myosin, in the other actin is stored.
Pituitary adenomas are the third most common primary intracranial tumors. Aggressive pituitary adenomas are a rare form of adenomas that pose a particular problem in diagnosis and treatment due to the lack of clear prognostic markers. This review provides an update on diagnostic criteria and discusses the clinical, immunologicaland molecular genetic aspects of aggressive pituitary adenomas.
Бугун хар бир ижтимоий, сиёсий, иқтисодий ва халқаро ўзгариш, ислоҳотлар умуминсоний маданиятга нима беради, деган савол нуқтаи назаридан баҳоланмоқда. Глобал тараққиёт миллий маданиятларни инкор этмайди, балки уларни янада ривожлантиришни, имкониятлардан фойдаланиб жаҳон ҳамжамиятини мустаҳкамлашни назарда тутади. Жахон халклари интеграция ва глобализация йўлидан бораётган экан, ушбу жараёнларни позитив воқеликка айлантириш учуй миллий маданиятлар олдидаги муаммоларни хам хал этиш талаб қилипади.
The article examines the internal, immanent features of Uzbek ethnoculture, aspects related to the national idea. The national ideological and ideological essence of artistic and aesthetic images and images in Uzbek ethnoculture is revealed. Forming an aesthetic ideal is the main function of Uzbek ethnoculture. In the article, the features of this function, issues of wider use of ethnocultural possibilities for its formation are studied from the point of view of national idea and ideology.
В данной статье приведены перспективные и широко используемые в транспортном строительстве способы усиления земляного полотна с применением геотекстиля в качестве армирующей и разделяющей прослойки. Экспериментально были проведены работы по устройству покрытий из геотекстиля на железнодорожном участке Кокандской дистанции пути. Приведен анализ первичных результатов мониторинга состояния геометрии рельсовой колеи экспериментального участка, который показал хорошую эффективность использования геотекстиля для усиления основной площадки земляного полотна.
The second half of the twentieth century is remarkable for the development of memoir literature and the significant interest in it of both readers and literary critics, because of increasing in the selfconsciousness of a human being who realizes his close connection with history. The study of the development of memoir literature from the point of view of the history of individual art forms, the analysis of the genre and poetic specificity of works opens up wide opportunities for understanding the general trends and evolution of memoiristics as a whole. This article makes an attempt to trace the historical stages of the origin and development of Hindi memoir literature and determine in it the place of the outstanding Hindi writer Vishnu Prabhakar who through the prism of artistic perception in his memoir works depicts the era of his time by subjectively understanding the changes taking place not only in the structure of Indian society but also in its mind.
This article outlines the genesis and subject matter of culture. Also, the origin of the Uzbek ethnonym was researched.
The topicality of the subject matter of this article is revealed by the fact that there are many students as a whole. Countries around the world learn English, so foreign language education, especially English Easier and more effective with the help of various innovations. The use of innovation is based on improvement. Areas of vocabulary and grammar; various skills: reading, listening, speaking, writing. It involves various innovations. It's important to be clear what your main goals are to focus on in the lesson.
One receives the disputes that occur during working hours,
decisions made by the administration which are sometimes contrary to the imagination and needs of the employee, as a matter of course, because work time is a responsibility imposed by the social system. A person obeys the above decisions and judgments, knowing that he must take on this responsibility, and strives to
fulfill them in full. However, after work, especially in leisure time, a person does not accept all the views, norms, decisions that are present in a given society. He prefers to assimilate only the values that correspond to his interests and needs, to receive spiritual nourishment from them. He does not accept values or actions that
do not suit his interests and needs, or openly denies them. Since ethnoculture is based on the spiritual, national and cultural needs and interests of the nation, formed over the centuries, it is impossible to adopt an attitude of indifference towards ethnocultural traditions. This phenomenon can account for the permanence of traditional values, the growing interest of our youth in the historical and cultural heritage, traditions of national holidays and rites. The article describes the methods of recreation and leisure in the ethnoculture of the Uzbek people with the example of calendar holidays, recreational festivals, nature-related ceremonies.
Mazkur maqolada talabalarning g‘oyaviy-mafkuraviy bilimini rivoj lantirish muammosining falsafiy-pedagogik adabiyotlarda o‘rganilishi yoritib berilgan, muallif tomonidan nazariy materiallarni tahlil etish asosida “ta’lim tarbiya”, “g‘oya-mafkura”, “immunitet-mafkuraviy immunitet” tushunchalari mohiyatini ochib bergan.
This article describes the social features of ethnoculture. It is emphasized that one of the main social characteristics and essence of ethnoculture is that it encourages people to create new cultural assets, to create, to search, to make the environment more beautiful, pleasant, and humane. The process of globalization and popular culture are also discussed.
The authors of the article considere the experience of decentralization of government in the countries of Eastern Europe and some other countries. Also models of the development of local self-government were presented.