This article provides data on the main fungal diseases of dog rose in the conditions of the Tashkent Botanical Garden. The main diseases and their causative agents and signs of such diseases as rust, powdery mildew, gray rot and various spots have been studied.
The results of the study were used to develop measures to combat rosehip fungal diseases. To suppress the spread of rosehip spots, Previkur SL 722 c.c. preparations were used. at two consumption rates and Falcon 46% e. The biological effectiveness of the drugs used was studied. Thus, the maximum value was noted in the variant with Previkur SL 722 v.r.k. at a consumption rate of 1.5 kg / ha, which was 90.9% on day 15, and by 30 - 86.5%. For the fungicide Falcon 46% ae. (0.5 l / ha), biological efficiency was 78.2% on day 15 and 66.8% on day 30. Against powdery mildew, we used fungicides Ridomil Gold 68% w.g. at a consumption rate of 2.5 kg / ha and powder of ground sulfur (20 kg / ha). fungicide Ridomil Gold 68% w.dg, showed biological effectiveness on leaves on day 15 - 74.8%, on stems - 71.3%, however, these indicators on day 30 were 75.2% and 72.2%, respectively , on the 45th day the indicators decreased. In the case of sulfur, 20 kg / ha, the indicators were on the 15th day, on the leaves - 71.5%, on the stems 70.6%, on the 30th day - on the leaves 71.3% and on the stems 70.6%..
Since ancient times, the inhabitants of Central Asia have used a producing economy. In this way, they were helped by the skills gained by observing the movement ofcelestial bodies such as the Moon and the Sun. Our forefathers were able to accurately predict the timing of seed sowing, the irrigation season, and harvest time thanks to regular observation of their movement. These abilities developed over millennia and resulted in Chronology, the study of calculating time. The research of several Central Asian scientists who made a significant contribution to the development of chronology is the subject of this article.
The aim of the study is to development of an algorithm for managing pregnancy and childbirth by studying the functional state of the mother-placenta-fetus system in pregnant women who have undergone COVID-19 in different trimesters of pregnancy.
The object of the study was 105 pregnant women who, were treated at the Samarkand Regional Perinatal Center and a specialized maternity center for pregnant women with COVID-19
Тhe scientific novelty of the research consists of the followings: for the first time in pregnant women infected with COVID-19, a relationship was established between the course of pregnancy, childbirth, the postpartum period and the development of complications depending on the trimester and severity of the disease; a direct correlation has been established between the state of the vessels of the mother-placenta-fetus system (resistance and pulsation indices, Endothelin-1 indicators), disorders in the hemostasis system (D-dimer, platelet aggregation) and the clinical course of the disease in pregnant women who underwent COVID-19; it has been established for the first time that the developed scale for assessing risk factors for non-developing pregnancy in women infected with COVID-19 (age, BMI, obstetric history, gestation period, hemostasis system status, endothelial function and severity of the disease) can serve as a prognostic marker of the degree of risk of pregnancy complications; it was proved for the first time that the choice of effective therapy for restoring hemodynamics in the mother-placenta-fetus system, in women who underwent COVID-19 at different stages of pregnancy, leads to a decrease in the number of thrombophilic complications.
Implementation of the research results. The results of the scientific research were introduced into the practical activities of the Samarkand Regional Perinatal Center by Order No. 128/1 of 01.09.2022 and the Samarkand City Maternity Complex No. 1 by order No. 58/1 of 03.10.2022. In pregnant women who underwent COVID-19 at different periods of pregnancy, changes in the mother-placenta-fetus system were determined using simple and effective research methods, such as ultrasound and Dopplerography, and this saved 53,000 soums; obstetricians and gynecologists, as well as neonatologists and therapists, are needed to diagnose signs of complications in the echocartin, that is, it has been proven that there is no need for other highly qualified specialists for this, due to the lack of need to train new personnel, state budget funds have been saved. With early detection of disorders in the hemostasis system in pregnant women with COVID-19: the period of stay of patients in the hospital was reduced from 10.5 days to 7.5 days and the number of hospital bed days was reduced; due to the reduction of the period of stay in the hospital for several days, the number of necessary drugs was reduced (on average, drugs are used for 1 day in the amount of 130,000 soums). Examination of pregnant women infected with viral diseases using simple and effective research methods such as ultrasound and Dopplerography served to save 85,000 soums: in the early stages up to 16 (10-11 weeks. - fetometry), 19-21, 32-34, 38-40 weeks of pregnancy; due to the absence of the need to use other research methods, it was possible to reduce costs by 23.5%; early detection of changes in the hemostasis system and endothelial dysfunction using fast, budgetary and effective research methods, contributed to the prevention of possible pregnancy complications, as well as the absence of the need to use long-term and expensive research methods, and this saved 106 000 soums: the coagulogram was checked in 105 (100%) patients, time was saved and efficiency was increased; endothelin-1 was also determined in 105 (100%) patients, efficiency was increased by 78.6%.
Improving the functionality of blood circulation in the uteroplacental and fetal-placental systems, a comprehensive analysis of possible complications during pregnancy and childbirth in women who have had viral infections, improving diagnostic, preventive and prognostic measures for managing pregnancy and childbirth contributed to the birth of live, full-term and healthy newborns in women who experienced COVID-19 during pregnancy, as well as a decrease in maternal mortality and perinatal mortality, 43% of women underwent rehabilitation in the postpartum period, 23.8% of women who underwent severe COVID-19 improved their quality of life.
To introduce scientific novelty on the topic “The impact of COVID-19 on the state of hemodynamics in the mother-placenta-fetus system in pregnant women”, a letter was sent to the Ministry of Health from Samarkand State Medical University on November 9, 2022 under No. 4295 (Conclusion of the Ministry of Health No. 8 n-z / 679 of December 15, 2022).
The structure and volume of the dissertation. The content of the dissertation consists of an introduction, five chapters, conclusion, list of used references. The volume of the dissertation consists of 113 pages.
Recent studies indicate the prevalence of myopic refraction in children with pseudophakia, which significantly reduces the functional results of treatment and may be an indication for replacing the intraocular lens (IOL). Therefore, studies conducted to achieve the target refraction in children with pseudophakia are relevant.
Purpose — to determine the risk factors for the prognosis of myopic refraction in children after extraction of congenital cataract and IOL implantation.
Material and methods. The study presents the results of refraction examination in 69 (110 eyes) children aged 1 to 12 years 36 months after extraction of congenital cataract with implantation of soft IOL.
Results. The obtained data of anamnesis, results of ophthalmological, echobiometric, clinical and laboratory studies were subjected to statistical processing assessing the significance of differences in outcomes depending on the impact of possible risk factors for the development of pseudophakic myopia; a regression logistic model and a ROC-curve were constructed.
Conclusion. According to the authors, reliable risk factors for the development of pseudophakic myopia in children can be such indicators as axial eye length at the time of IOL implantation exceeding the age norm by more than 0.2 mm; the child from the first pregnancy; the AL/CR ratio of 23.0; myopia on the paired eye; strabismus of more than 4 prism diopters; hereditary load; tension of eye's fibrous capsule: pressure of SI 80 mm Hg at the time of IOL implantation. The presented reliable factors, as well as a combination of less significant signs (the child being outside for less than 1 hour per day, intermarriage of the patients parents, near-sight visual loads ot more than 3 hours per day, the blood Ca level of less than 1.8 mmol/L) can be used for prognosis of the development of pseudophakic myopia and to help make adjustments in the management tactics for patients to achieve target refraction.
На сегодняшний день одной из самых важных проблем в стоматологии любого возраста является “одонтофобия” Специфика детского приема заключается в психоэмоциональной нестабильности пациента, что часто приводит к: вынужденному положению, обморокам, гиперактивности, шоку и психическим травмам. Поэтому по сей день стоматологи ищут универсальное седативное средство которое не только облегчит прием пациентов, но и будет абсолютно безвредным для несовершеннолетнего организма. В 21 веке таким является - Закись азота.
An adverb is a lexico-grammatical class of unchangeable, as a rule, words denoting a sign of an action, quality or object and acting in the syntactic function of a circumstance or definition, less often of a predicate. The adverb in all languages of the world belongs to the late parts of speech, the formation process of which continues to the present day. At the same time, words belonging to this category still retain their functions in other parts of speech from which they were formed. Another distinctive feature of the adverb is the conceptual heterogeneity of the class of words in comparison with other parts of speech. Based on the above, we can say that there are many definitions of adverbs in Afghan and Iranian studies. Previously, the works of Arab scholars served as the basis for studying the grammar of Dari and the Persian languages; today, Afghan and Iranian philologists admit that there are significant differences between Arabic and their languages, and therefore, in studying the grammar of their language, they try to take into account the grammatical features exclusively Farsi. It should be noted that there is an activity of Iranian philologists in the field of writing scientific articles and books devoted to the interpretation of a particular grammatical issue, the attention of researchers to the structure of syntax has increased. We have analyzed a number of works on the grammar of the Dari and Persian languages, which touch on the question of parts of speech and minor members of a sentence. Below is a brief description of some works on the grammar of the modern Dari and Persian languages, in which the question of our research is most fully considered. In world linguistics, the Dari language is not widely studied, like the Persian language. In Iranian studies, in the scientific description of this language, it is mainly noted that it differs from the modern Persian language. In the Dari language, as well as in the Persian language, the authors consider the adverb from a morphological and syntactic point of view. In the course of our research, we analyzed the works related to the modern Dari language, as well as unique works that are being republished for the second time in Afghanistan
This work is to study the effectiveness of topical glucocorticosteroids in the treatment of adenoid vegetations in preschool children. The study included 50 children (mean age 4.25 ± 0.24 years) with adenoid vegetations. The patients were divided into 2 groups. Group 1 included 25 children (mean age 4.0 ± 0.22 years) who received irrigation therapy with fluticasone furoate, 1 injection of 55 μg into each half of the nose once a day for at least 1 month. Group 2 - 25 children (average age 4.5 ± 0.5 years), who were prescribed irrigation therapy with saline solution, 3-5 ml in each half of the nose 3 times a day for at least 1 month. Intranasal use in patients with adenoid vegetations of fluticasone furoate for a month led to a decrease in the size of the hypertrophied pharyngeal tonsil and an improvement in nasal breathing, thereby improving the quality of life of a sick child.
Актуальность изучения базальноклеточного рака кожи продиктована тем, что данная опухоль является самой распространенной, и инциндентность в настоящее время растет. В структуре кератиноцитарных опухолей на долю БКК приходится 80%. По данным эпидемиологических исследований соотношение частоты сквамозноклеточного рака кожи (плоскоклеточного СКК/ПКК) и базальноклеточного рака кожи было иным: ранее преобладал СКК по частоте, и соотношение составляло 5:1. На сегодняшний день инциндентность БКК значительно возросла, и соотношение уже БКК к СКК составляет 2:1. Главными независимыми факторами риска возникновения БКК на сегодняшний день считаются мужской пол и возраст. Так, соотношение мужчин и женщин с БКК составляет 1,5-2:1, что соответствует полученным нами результатам.
На сегодняшний день все больше увеличивается количесвто больных H. pylori ассоцированной язвенной болезнью. По последним уточнённым данным 38 % язв желудка во всем мире связаны с инфекцией H. pylori , поэтому каждому врачу общей практики придется столкнуться с пациентами, которым необходима антихеликобактерная терапия. В настоящее врмя наблюдается резкое увеличение числа штаммов НР, устойчивых к нитроимидазолам. С учетом этого актуальной задачей на сегодняшний день представляется поиск более действенных режимов эрадикации НР. Поэтому в последние годы растет интерес к применению макролидов при лечении НР- ассоциированной язвенной болезни. Многочисленными работами показана эффективность применения макролидов для эрадика- ции НР. Эти препараты обладают высокой способностью проникать в летки, интенсивно выделяются на слизистые оболочки,что увеличивает ихэффективность против НР.
The President of the Republic of Uzbekistan Shavkat Mirziyoyev in his Address to the Oliy Majlis on December 29, 2020, noted that in the face of today's complex geopolitical processes, the coronavirus pandemic and the global economic crisis, Uzbekistan is actively pursuing an open and pragmatic foreign policy. He noted that as a result of our efforts, the prestige of the country is growing, and priorities for the implementation of foreign policy for 2021 have been outlined. Among the tasks that need to be given special attention in the implementation of the country's foreign policy in 2021, listed by the leader of Uzbekistan, are proposals and initiatives for the development of public diplomacy and cultural diplomacy, which are important areas of foreign policy and diplomacy of Uzbekistan. The idea of creating a Compatriots Fund was formulated by the United Nations General Assembly Resolution on the celebration of July 30 as International Day of Friendship in order to inspire efforts to strengthen friendship and peace between nations, cultures and peoples, and to build bridges between societies respecting cultural diversity July 30 - International Day of Friendship and the holding of the international conference "Central Asia at the crossroads of world civilizations" in cooperation with UNESCO in Khiva in 2021 formed a goal: to increase the prestige and image of Uzbekistan in the world (this historical initiative of the President of the Republic of Uzbekistan Mirziyoyev Sh.M. nominated at the 75th session of the UN General Assembly).