Patients with diseases of the paranasal sinuses make up, according to various sources, from 15% to 62% of the total number of those who applied to ENT hospitals, ENT offices of polyclinic medical institutions. .Approximately 30% of women experience rhinitis symptoms during pregnancy.
The article demonstrates the effect of genetically engineered biological therapy on the clinical course of systemic onset juvenile arthritis in children. The analysis of the results showed that the administration of human monoclonal antibodies against the IL-6 receptor - a geneticallyengineered biological drug (tocilizumab) was confirmed by normalization of clinical symptoms and laboratory parameters, reduced disease activity, prevented oral administration of glucocorticoids and systemic initiating juvenile arthritis. provided the transition to the stage. The results obtained showed that the addition of tocilizumab to the complex treatment of systemic onset juvenile arthritis was correct, and confirmed its high efficacy in the treatment of this orphan disease in children.
The results of the studies revealed that SoJIA is characterized by varying stages of arthritis activity, severe course with minor and majorcriterias of the disease and frequent relapses, as well as with an extremely high level of laboratory activity as leukocytosis, thrombocytosis, progressive anemia, significantly elevated ESR, high levels of CRP and LDH.
In this article, it is stated that the promotion of Berdaq’s creative heritage among the young people of the institute has an effective effect on raising the spirituality of young people and inspiring them to noble goals. It is also stated that one of the effective methods of promotion is its use in medical education.
The article presents the results of a study of 189 children with juvenile idiopathic arthritis. The results of the study show that the prevalence of oligoarthritic (33.8%), polyarthritic (32.8%) and systemic (27.5%) forms of diseases is observed in the frequency of occurrence of various forms of juvenile idiopathic arthritis. In children, juvenile idiopathic arthritis can debut at any age and is characterized by varying degrees of arthritis activity, and the systemic form of the disease is characterized by the predominance of systemic manifestations, severe course of the disease and frequent relapses.
XX ва XXI асрлар чегарасида бутун дунёда юз берган оламшумул ижтимоий узгаришлар Уйгониш даврида вужудга келган цивилизация типидан инсоннинг кундалик хдётидан энг янги технологиялар, шу жумладан ахборот технологиялари кенг урин эгаллаши билан богликбулган янгича типдаги цивилизацияга утиш билан тавсифланади (бу ерда мухими шундаки, ахборот постиндустриал жамият коди булиб хизмат килади).
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The article presents the results of evaluating the effectiveness of a genetically engineered biological drug (tocilizumab) in children with juvenile arthritis with a systemic onset. Analysis of the results of the study showed that the use of a genetically engineered biological drug (tocilizumab) in the treatment of patients with juvenile arthritis with systemic onset contributes to a decrease in disease activity, regression of systemic signs and normalization of laboratory parameters in a significantly short time and improves the prognosis of the disease in these children.