В данной работе рассмотрена возможность формирования элементов врачебного мышления на основе применения законов логики в ходе преподавания частной гистологии. С целью развития у студентов мыслительных процедур, таких как анализ, синтез, рассуждение путем индукции и дедукции, аналогии и абстракции, необходимо включать соответствующие задания в традиционные ситуационные задачи, используемые в учебном процессе. В специально разработанных методических рекомендациях к ситуационным задачам для студентов должно быть доходчиво разъяснено понятие врачебного (клинического) мышления, структура мыслительного процесса, а также аргументирована значимость формирования элементов врачебного мышления на ранних этапах обучения. На примере конкретной ситуационной задачи даны алгоритмы ее решения в виде логически последовательных вопросов, сформулированных в соответствии с условиями задачи, ответы на которые приведут к правильному ее решению.
The aim of the research work is determination of the prospects for the use of a domestic agent for the prevention of adhesion formation in thoraco-abdominal surgery on the basis of experimental and morphological studies.
Research objectives were white outbred rats in the amount of 62 individuals, in two experimental studies on the abdominal and pleural cavities, in each series of experiments the studies were carried out in 2 comparative groups, control and main. Experiments on the formation of adhesions in the abdominal and pleural cavities were carried out on the basis of the Republican Specialized Scientific and Practical Medical Center of Surgery named after acad. V.Vakhidov in the Department of Experimental Surgery for the period from 2019 to 2020.
The scientific novelty of the research consists of the followings: it is proved according to the data of experimental research that when modeling the adhesion process in the abdominal cavity, the local application of an anti-adhesion coating made of cellulose derivatives reduces the processes of adhesiogenesis and the development of changes in architectonics, bends and narrowings of the intestinal lumen; it was found in an experimental study that when modeling the adhesion process in the chest cavity, the local use of an anti-adhesion implant provides a significant decrease in the risk of adhesiogenesis in the form of the formation of coarse adhesions or planar adhesions; it was determined that when blood serum was applied over a powder implant, the quality of adhesion and the uniformity of its distribution on the surface of the experimental defect of the peritoneum or lung did not change, but, in contrast to activation by blood (to ensure a hemostatic effect), it was not accompanied by the development of cellular inflammation due to the resorption of thrombotic masses; it was found that the formation of a gel film over the area of damage to the peritoneum in the absence of cellular elements of blood makes it possible to achieve biodegradation of the coating without a pronounced cellular-inflammatory reaction, providing cicatricial replacement of defects with a significant reduction in the risk of developing a massive adhesive process; the morphostructural features of the formation of the adhesive process when using an anti-adhesive coating, characterized by regression in the dynamics of the number of connective tissue cells of the inflammatory infiltrate with scarring of the defect zone without the development of adhesive conglomerates with the surrounding tissues, have been determined.
Introduction of the research results. According to the results of a scientific study on a comparative analysis of the use of a domestic agent for the prevention of adhesion formation in thoraco-abdominal surgery: methodological recommendations were developed: "New technologies for the prevention of adhesions in thoraco-abdominal surgery" (certificate of the Ministry of Health No. 08-09/10055 of August 12, 2021). The proposed recommendations for performing surgical interventions on the organs of the abdominal and thoracic cavities will allow for sparing local hemostasis, as well as prevent the formation of a coarse adhesive process in the abdominal cavity.
The obtained scientific results on a comparative analysis of the use of the domestic remedy for the prevention of adhesion formation in thoraco-abdominal surgery have been introduced into the practical activities of health care, including in the Republican Specialized Scientific and Practical Medical Center for Surgery named after V.I. Academician V. Vakhidov, surgical departments of the clinics of the Andijan and Samarkand State Medical Institutes (certificate of the Ministry of Health No. 08-09/10055 of August 12, 2021). Based on the proposed results of experimental studies, it was shown that the use of an anti-adhesive coating made of cellulose derivatives made it possible to reduce the risk of adhesion formation from 60% to 20%, bowel deformation without manifestations of obstruction from 33.3% to 13.3% and the possibility of acute adhesive intestinal obstruction from 6.7% to 0%.
Structure and scope of the dissertation. The dissertation consists of an introduction, four chapters, conclusions, practical recommendations and a list of cited literature. The volume of work is 113 pages.
Language is a carrier of culture, and language reflects not only the real existence that surrounds a person, but also the social self-consciousness of the people, its mentality, national character, lifestyle, traditions, customs, morals, values and worldview. The article deals with the main objectives of linguoculturology, the development of folklore, linguistic and cultural science, emotional-color elements of military vocabulary, the factors influencing the development of military vocabulary, the task of choosing vocabulary for vocabulary, the most difficult tasks facing linguists and the role of linguoculturology in the making of military terms.
Аннотация. В данной статье рассмотрены перспективы развития нормирования энергосбережения в области строительства, краткое содержание изменения в строительных нормативных документах. Целии задачи Стратегии развития энергоэффективности поставленные на 2022-2026 годы. В соответствие с принципами системного подхода математическую модель теплового режима здания как единой теплоэнергетической системы целесообразно представить в виде трех взаимосвязанных моделей, более удобных для изучения: - математической модели теплоэнергетического воздействия наружного климата на здание; - математической модели теплоаккумуляционных характеристик оболочки здания; - математической модели теплоэнергетического баланса помещений здания. Оптимизационная задача для энергоэффективного здания имеет следующее содержание: определить показатели архитектурных и инженерных решений здания, обеспечивающих минимизацию расхода энергии на создание микроклимата в помещениях здания. В статье представлены решения оптимизационной задачи, включающей в себя реализацию математических моделей здания как единой теплоэнергетической системы, также показано, что решение, например, задачи оптимального управления расходом энергии при на топе помещений, обеспечивает более 70% экономии энергии.
The aim of the study is to improving the quality of treatment of ventral hernias in patients with morbid obesity by improving the tactical and technical aspects and optimizing the choice of hernioplasty method.
The object of the study were 121 patients with ventral hernias and morbid obesity who were hospitalized in the surgical department of the 1st clinic of the Samarkand State Medical University in the period from 2012 to 2021.
The scientific novelty of the study is as follows: a method was developed for preoperative preparation of patients with ventral hernia and morbid obesity using a modified pneumatic belt-bandage to adapt the cardiovascular and respiratory systems to intra-abdominal hypertension after hernioplasty; improved technical aspects of the reconstruction of the anterior abdominal wall in patients with morbid obesity; the surgical instrument "retractor" has been improved for technical optimization of the stage of suturing the anterior abdominal wall for fixing the prosthesis in patients with concomitant obesity and abdominal ptosis; clarified clinical and instrumental criteria for the specific unification of the scale for assessing the quality of life of patients after hernioplasty and abdominoplasty for ventral hernias and morbid obesity with differentiation of the value of physical, mental and social daily activity. The practical results of the study are as follows: According to the results of a scientific study to improve the diagnosis and surgical treatment of patients with ventral hernias and morbid obesity: improved "retractor". The use of the proposed tool made it possible to level the technical difficulties in fixing the prosthesis against the background of severe overweight with a reduction in the operation time; developed guidelines "Technical aspects of hernioplasty for ventral hernias in patients with morbid obesity" (certificate of the Ministry of Health 8n-r / 905 dated October 12, 2021), "Criteria for the choice of surgical treatment of patients with ventral hernias and obesity" (certificate of the Ministry of Health 8n-r /906 dated October 12, 2021). The proposed recommendations made it possible to optimize the choice of tactics for surgical treatment of patients with ventral hernias and morbid obesity; the obtained scientific results on improving the quality of diagnosis and surgical treatment of patients with ventral hernias and morbid obesity have been introduced into the practice of health care, in particular, in the departments of surgery of the 1st clinic of the Samarkand State Medical Institute, the Jizzakh Regional Multidisciplinary Medical Center and the Sh. Rashidov District Medical Association of the Jizzakh region (certificate of the Ministry of Health 8n-z / 368 dated October 22, 2021). The implementation of research results by improving the tactical and technical aspects of the surgical treatment of patients with ventral hernias and morbid obesity made it possible to reduce the overall incidence of postoperative complications from 14.8% to 8.9%, including wound complications from 11.1% to 4.5% and extra-abdominal from 7.4% to 4.5%, as well as significantly reduce the duration of surgical treatment and rehabilitation periods after various types of hernioplasty and abdominoplasty. The structure and scope of the dissertation. The dissertation consists of an introduction, five chapters, a conclusion, conclusions, practical recommendations and a list of cited literature. The volume of the text material is 107 pages.
In this article it is revealed the aims and tasks of proceeding in the first instace of economical court; it is given suggestions and recommendations directed for the development the economical procedural legislation, also it was made comparative analysis of economical procedural legislation of CIS countries.
The purpose of the study was to determine and evaluate the features of morphological changes in the liver parenchyma of 5-month-old white outbred rats under the influence of anti inflammatory drugs under conditions of polypharmacy.
The object of study for experimental studies was taken 250 white male rats weighing 200-250 g.
The scientific novelty of the research is as follows: polypharmacy of anti-inflammatory drugs negatively affects all parameters of liver structures. Under the influence of polypharmacy, there is a decrease in the absolute mass of the liver, volume and morphological parameters of the liver parenchyma. The decrease in morphometric parameters depends on the number of drugs in polypharmacy; under conditions of polypharmacy, the state of the hepatic capillaries and internal bile ducts, as well as biological membranes, was studied, as a result of which the structural structure of the liver, the development of destruction of the hepatic tissue were studied, and the morphofunctional foundations of this condition were shown.
Implementation of the research results. Based on the obtained scientific results, the morphofunctional characteristics of the liver of rats in the norm and under the influence of polypharmacy were determined:
Approved methodological recommendations: "Methodology for determining the morphometric parameters of the liver during polypharmacy of anti-inflammatory drugs" (Conclusion No. 8n-r / 265 dated 14.03.2022 of the Ministry of Health of the Republic of Uzbekistan) and "Methodology for determining the morphometric parameters of the liver during polypharmacy of anti-inflammatory drugs" (Uzbekistan, Conclusion of the Ministry of Health of the Republic of Uzbekistan No. 8 n-z 180 of 2022), electronic program No. DGU 1038 "Program for studying the comparative characteristics of morphological changes caused by polypharmacy in the liver."
The scientific results obtained in the study of morphological and functional properties and morphometric changes in the structure of the liver under the influence of polypharmacy have been introduced into the practice of the Samarkand branch of the Republican Specialized Oncological and Radiological Scientific and Practical Medical Center of the Samarkand City Medical Association (Order of the Ministry of Health of the Republic of Uzbekistan dated March 14, 2022, 8n-r / 265-No. and conclusion No. 8 n-z 180 of 2022). The implementation of the obtained research data allows developing methods for early diagnosis, treatment and prediction of organopathology by morphological parameters, improving the quality of life and reducing the number of complications.
The structure and scope of the dissertation. The structure of the dissertation consists of an introduction, three chapters, a conclusion and a list of references. The volume of the dissertation was 103 pages.
This scientific article analyzes the importance of the conceptual ideas put forward in the address of the President of the Republic of Uzbekistan to the Parliament of December 28, 2018. Special attention is paid to their importance in raising large-scale reforms in the country to a new level, carried out on the basis of an Action strategy. In particular, the issues of deepening globalization processes occurring in the world and difficult international situation under its influence, the need to take into account the international situation in the process of independent political development, the main tasks of further improving the effectiveness of the political system, democratizing society at the current stage of our country are illuminated in it. The President’s address paid special attention to improving the practice of strengthening parliamentary oversight over decisions, passing laws and applying democratic mechanisms in the activities of parliament. The article also deals with the optimization of the executive system, justified in the address of the President, about topical issues of increasing the efficiency of the activities of the Cabinet of Ministers. The author of the article talks about the most advanced models of modern democracy being implemented in our country. In particular, he sets forth his analytical thoughts on such concepts as “Democracy of monitoring”, “Deliberative democracy”, “E-democracy”, “Mobile democracy” and on other new models of democracy. The article analyzes the great goals and objectives related to the achievement of great results, based on modern mechanisms and principles of democracy in the context of the implementation of innovative state policy containing the actual needs of our country’s renewal and development based on the most advanced requirements of our time, which were set forth in the address of the President. At the same time, it is shown that the leading principles, the philosophy of the implementation of innovation policy express the expectations and aspirations of our people. In this regard, the article presents the conclusions about the importance of the implementation of modern innovative democratic development in society.
The article defines the objectives of agricultural development in the system of territorial division of labor for the future, taking into account the emerging conditions of increasing water scarcity and
environmental tension, and developed proposals for the reorientation of the territorial and intersectoral structure of the agro-industrial complex of the Republic on the basis of improving the specialization of agricultural production.
At the same time, the main principles of the mechanism of economic regulation in the agro-industrial complex, capable of ensuring intersectoral changes taking into account the interests of the Republic, regions and producers of products, have been identified.
The main purpose of the research is to define the task in the areas of poverty reduction, socio-economic development of the regions, transformation of enterprises with state participation, formation and
implementation of investment policy, development of entrepreneurship in the country.
The aim of the study is to development of an algorithm for managing pregnancy and childbirth by studying the functional state of the mother-placenta-fetus system in pregnant women who have undergone COVID-19 in different trimesters of pregnancy.
The object of the study was 105 pregnant women who, were treated at the Samarkand Regional Perinatal Center and a specialized maternity center for pregnant women with COVID-19
Тhe scientific novelty of the research consists of the followings: for the first time in pregnant women infected with COVID-19, a relationship was established between the course of pregnancy, childbirth, the postpartum period and the development of complications depending on the trimester and severity of the disease; a direct correlation has been established between the state of the vessels of the mother-placenta-fetus system (resistance and pulsation indices, Endothelin-1 indicators), disorders in the hemostasis system (D-dimer, platelet aggregation) and the clinical course of the disease in pregnant women who underwent COVID-19; it has been established for the first time that the developed scale for assessing risk factors for non-developing pregnancy in women infected with COVID-19 (age, BMI, obstetric history, gestation period, hemostasis system status, endothelial function and severity of the disease) can serve as a prognostic marker of the degree of risk of pregnancy complications; it was proved for the first time that the choice of effective therapy for restoring hemodynamics in the mother-placenta-fetus system, in women who underwent COVID-19 at different stages of pregnancy, leads to a decrease in the number of thrombophilic complications.
Implementation of the research results. The results of the scientific research were introduced into the practical activities of the Samarkand Regional Perinatal Center by Order No. 128/1 of 01.09.2022 and the Samarkand City Maternity Complex No. 1 by order No. 58/1 of 03.10.2022. In pregnant women who underwent COVID-19 at different periods of pregnancy, changes in the mother-placenta-fetus system were determined using simple and effective research methods, such as ultrasound and Dopplerography, and this saved 53,000 soums; obstetricians and gynecologists, as well as neonatologists and therapists, are needed to diagnose signs of complications in the echocartin, that is, it has been proven that there is no need for other highly qualified specialists for this, due to the lack of need to train new personnel, state budget funds have been saved. With early detection of disorders in the hemostasis system in pregnant women with COVID-19: the period of stay of patients in the hospital was reduced from 10.5 days to 7.5 days and the number of hospital bed days was reduced; due to the reduction of the period of stay in the hospital for several days, the number of necessary drugs was reduced (on average, drugs are used for 1 day in the amount of 130,000 soums). Examination of pregnant women infected with viral diseases using simple and effective research methods such as ultrasound and Dopplerography served to save 85,000 soums: in the early stages up to 16 (10-11 weeks. - fetometry), 19-21, 32-34, 38-40 weeks of pregnancy; due to the absence of the need to use other research methods, it was possible to reduce costs by 23.5%; early detection of changes in the hemostasis system and endothelial dysfunction using fast, budgetary and effective research methods, contributed to the prevention of possible pregnancy complications, as well as the absence of the need to use long-term and expensive research methods, and this saved 106 000 soums: the coagulogram was checked in 105 (100%) patients, time was saved and efficiency was increased; endothelin-1 was also determined in 105 (100%) patients, efficiency was increased by 78.6%.
Improving the functionality of blood circulation in the uteroplacental and fetal-placental systems, a comprehensive analysis of possible complications during pregnancy and childbirth in women who have had viral infections, improving diagnostic, preventive and prognostic measures for managing pregnancy and childbirth contributed to the birth of live, full-term and healthy newborns in women who experienced COVID-19 during pregnancy, as well as a decrease in maternal mortality and perinatal mortality, 43% of women underwent rehabilitation in the postpartum period, 23.8% of women who underwent severe COVID-19 improved their quality of life.
To introduce scientific novelty on the topic “The impact of COVID-19 on the state of hemodynamics in the mother-placenta-fetus system in pregnant women”, a letter was sent to the Ministry of Health from Samarkand State Medical University on November 9, 2022 under No. 4295 (Conclusion of the Ministry of Health No. 8 n-z / 679 of December 15, 2022).
The structure and volume of the dissertation. The content of the dissertation consists of an introduction, five chapters, conclusion, list of used references. The volume of the dissertation consists of 113 pages.
The article analyzes the role and importance of technoparks in the imitation and innovative development of small and medium-sized enterprises (SMEs), the concept of a technopark, its structure, types, incubators, the main element of a classic technopark, their goals and objectives. The goals, objectives, management system and constraining factors for the development of "Yashnobad" technopark and measures for its development have been studied.
This article analyzes the priority directions of social development at the present stage based on proposals, initiatives and conceptual ideas put forward in the Address of the President of the Republic of Uzbekistan to the Oliy Majlis in 2018. As noted in the article, the Strategy of Action on the five priority directions of development of the Republic of Uzbekistan in 2017–2021 contributes to the improvement of the strategic framework to ensure the vital needs and legitimate interests of the population and strengthen the foundations of a decent and comfortable life. In this regard, as noted in the article, the Address of the President of the Republic of Uzbekistan Shavkat Mirziyoyev to Oliy Majlis on December 28, 2018, and the fact that 2019 was proclaimed the “Year of Active Investments and Social Development” became the logical continuation of the years of “Dialogue with the people and human interests”, “Support for active entrepreneurship, innovative ideas and technologies” in the country. It indicates that in the third stage of the reform strategy, the importance of social development as a priority of state policy increases. According to the author, increasing the economic potential of the country by attracting investment will inevitably lead to the development of social spheres. The article focuses on the development of the social sphere. The author reveals the essence of the concept of “social development”. As noted, “social development” is a change that contributes to the emergence of new social relations, institutions, norms and values in society. In this regard, features and criteria of social development are shown. The article outlines the main tasks for the further development of the social sphere in 2019, as defined in the Presidential Address. In particular, comments were given to initiatives and conceptual ideas for further improvement of science, modern and continuing education, further strengthening of state social support for young people, and the development of a national idea. The article widely describes the concept of “investment in human capital” and the article notes that investments in human capital include expenditures on health care, general and special education, employment, vocational training, raising children and others. The effectiveness of such investments is reflected in the pace of development of society in all areas. The article shows how the issues of modern education and upbringing of young people and their social support are important in the social development of the country. The article analyzes important practical steps taken to ensure that the sphere of education and training directly serves further human improvement.
Современные технологии и телекоммуникации открывают широкие возможности перед высшим образованием и научными исследованиями. Они, безусловно, позволяют повысить качество учебно воспитательного процесса и мотивировать студентов и исследователей в получении новых знаний и сведений. В этой связи, поставленные перед Высшей школой задачи подготовки высококвалифицированных, конкурентоспособных, отвечающих современным требованиям, кадров – специалистов ХХI века, требуют незамедлительного их выполнения. В связи с этим являются актуальными вопросы подготовки специалистов – кадров с применением современных цифровых технологий, создание инновационных или технологических парков (технопарков) в этом направлении и др