Subject of the inquiry: 97 patients with ankylosing spondylitis, 20 healthy volunteers.
Aim of the inquiry: to assess metabolic activity of erythrocytes and peculiarities of fcrrokinctics in using Fhlogcnzymc in the complex therapy of patients with AS. Methods of research: functional-metabolic process erythrocytes and ferrokinctics (scrum iron, ferritin, saturation of transferrin with iron) lipid peroxidation and antioxidant system.
The results achieved and their novelty: For the first time purposeful complex study was conducted of metabolic process parameters in erythrocytes and fcrrokinctics, lipid peroxidation and antioxidant system processes, Willebrand factor, atherogenicity in relation to the clinical course of the disease. Functional-metabolic disorders in erythrocytes in fcrrokinctics determined systemic changes in blood, with their extent associating with severity of the clinical course of AS. For the first time it was found that the use of Fhlogcnzymc in the complex treatment improved clinical course of the disease. The shortening of clinical recovery period was associated with normalization of parameters characterizing functional metabolic activity in crythrocytea and ferrokinctics. Systemic enzyme therapy was proved to increase the effect of conventional therapy by a directed improvement of functional metabolic processes in erythrocytes, energetic activity and ferrokinctics which allowed inclusion of systemic enzyme therapy preparations for hemic hypoxia in patients with AS.
Practical value: Use of Fhlogcnzymc in the complex treatment of AS increased the efficacy of therapy, decreased the rate of drug side-effects, allowed us to decrease the doses of basic preparations and non-stcroid anti-inflammatory. Changes of laboratory parameters in Fhlogcnzymc using included more significant decrease of acute phase indices, increase of hemoglobin and erythrocyte concentration in the peripheral blood.
Degree of inculcate and economic efficiency: conclusions and practical recommendations were introduced into the practice of departments of rheumatology, nephrology of the third clinic of the Tashkent Medical Academy and into teaching process of departments of faculty and hospital therapy, folk medicine, internal diseases of the stomatological faculty and clinical pharmacology of the Tashkent Medical Academy.
Sphere of usage: rheumatology, therapy.
Существует много людей, не только в нашей стране, но и во всём мире, которые страдают гиподинамией, то есть недостатком двигательной активности.
The socio-political activity of youth is an indicator of the processes taking place in modern society. Since the young generation is the main mobilization resource of society, which determines the future of the state. This article is devoted to youth policy, international legal documents developed by the UN, the growing relevance of this issue in connection with the deepening of globalization processes and the ensuing dangers and challenges covering all countries, the solutions of which are impossible without the active participation of young people, a question that is always one of the priority tasks of the international community and in particular the UN. The international legal documents regulating the youth sphere are considered, since this issue has been an object of state policy in more than 130 countries of the world since the middle of the 20th century. In the way in which the state organizes its youth policy, two models stand out - European and Anglo-Saxon. The European model is based on the leading role of the state in the field of youth policy. This model also clearly defines priorities, goals, objectives and expected results. The Anglo-Saxon model is characterized by an approach to support exclusively voluntary activity and youth organizations without the systematic participation of government bodies in the implementation of youth policy. The article analyzes the experience of youth policy in Japan and Uzbekistan, notes the similarities and features of approaches to solving problems and problems of this topic. It is noted that the socio-political system of Japan, unlike most developed countries of the world, for decades allows the government of this country to avoid major social upheavals and crises of social institutions. This, in turn, proves the effectiveness of government measures aimed at solving youth problems in Japanese society. Japan’s policy in this area has its own specifics, based on a combination of traditional preventive measures with innovative ones, which allows us to consider about its universality. The article comprehensively surveys the new course taken by Uzbekistan to increase the role of youth in the socio-political life of society. In this regard, emphasis is placed on the comprehensive support of youth initiatives, both from the state and from youth organizations. Based on this, it can be argued that an open dialogue with youth has become a strategic direction at a new stage in the development of Uzbekistan. In this strategy, a key place is given to increasing the social activity of youth, their involvement in the processes of formation of a modern, democratic state.
Для модернизированной науки проблема формирования физической активности подрастающего поколения является особо значимой и неизменно находится в центре внимания общества и государства. Именно физической активность является одним из важнейших качеств личности, которое формируется в деятельности, отличающейся общественно- значимыми мотивами и дающей общественно ценный результат. Современное общество от мала до велика подвержено гиподинамии. Еще недавно медики констатировали, что широкое приобретение автомобилей ведет к малоподвижному образу жизни, но сегодня, угрозой являются мобильные телефоны, планшеты и другие гаджеты, которые заменяют и взрослым, и детям и общение, и активные игры.
The search for new sources of highiy active drugs based on iocai raw materials is an urgent task of modern science, it is known that iicorice root is widely used in various sectors of the economy, the main component of it is glycyrrhizic acid. The presence of anti-inflammatory activity, iow toxicity and iack serious side effects make new synthetic derivative of glycyrrhizic acid promising for medicine compounds.
The purpose of the study. To study the antiulcer activity glycerinate on an experimental model of neurogenic uicers caused by 24-hour immobilization of animals and to identity the mechanism of antiulcer activity.