The lack of understanding of bilateral breast cancer is a much more complex problem for oncologists. Today the incidence of unilateral as well as bilateral breast cancer is much higher than 10 years ago, which makes this problem even more urgent. Information about the causes of bilateral breast cancer, important criteria for the development of the disease, early diagnosis of the disease and early detection of the possibility of bilateral metachronous cancer, as well as preventive measures are not fully covered in the literature, scientific studies. In this article, the authors analyze the data of the recommendations of the international scientific society and the results of large clinical trials on bilateral breast cancer. Also, important criteria in the development of metachronous and synchronous breast cancer were analyzed, the results of clinical and morphological, immunohistochemical aspects were studied. The reasons for the development and modern knowledge about the diagnosis of bilateral breast cancer have been studied. In particular, the authors reviewed and studied about 40 foreign and domestic scientific works devoted to this problem.
The article deals with the treatment of primary disseminated breast cancer. Statistics are presented that in various countries around 10% of patients treat stage IV disease. In most cases, these are patients with T3-4 and multiple metastases in the lymph nodes. Metastases are most often detected in bones, lungs, and liver, and several organs are also affected. Standards have not yet been developed and therefore there are disagreements regarding the tactics of treating patients in this category. The article presents data from multicenter scientific research and clinical recommendations for the treatment of patients with primary disseminated breast cancer, taking into account the biological characteristics of the tumor.
This article examines the theories of creating brand value in the Dairy and Dairy Market market, based on the fact that brand value depends on the elements and image of the Marketing MIX of the enterprise. The activities of Bio Natural Food LLC, which was selected as the object, aimed at increasing the brand value, were analyzed on the basis of the model of systemic equations (SEM). The results of the analysis allowed to determine the main directions for the use of branding strategies in Bio Natural Food LLC.
Бугунги кунда сут чорвачилигида маҳсулот таннархини тўғри калькуляция қилиш долзарб масалалардан ҳисобланади. Мазкур мақолада маҳсулот таннархини калькуляция қилиш масалаларига услубий ёндашувлар баён қилинган. Маҳсулот таннархини калькуляция қилишга иқтисодий луғатларда берилган, хорижлик ва иқтисодчи олимларнинг томонидан берилган таърифлар ва фикр-мулоҳазалар ўрганилган. Сут чорвачилигида маҳсулот таннархини калькуляция қилиш бўйича тегишли хулосалар шакллантирилган ва таклифлар берилган.
Ушбу мақолада озиқ-овқат маҳсулотлари бренд қийматини баҳолашнинг услубий жиҳатлари тадқиқ этилиб, муаллиф томонидан бренд қийматини баҳолашнинг хорижий тажрибалари ўрганилиб, муаллиф томонидан озиқ-овқат маҳсулотлари брендини баҳолашнинг бўйича илмий таклиф ва тавсиялар тақдим этилган.
Ушбу мақолада болалар озиқ-овқат маҳсулотлари бозорида маркетинг тадқиқотлари ўтказиш ва болалар озиқ-овқат маҳсулотлари бозори ривожланишининг илмий-амалий жиҳатлари ўрганилган. Болалар озиқ овқат маҳсулотларини ишлаб чиқаришни шакллантириш ва ривожлантиришнинг лойиҳавий босқичлари таклиф этилган.