The aim of the study was to identify the mechanisms of the toxic effect of intrauterine and early postnatal exposure to pesticides on the development of the immune system of offspring. Experiments were performed on white adult female rats, which are obtained respectively pesticides cyhalothrin or fipronil during the pregnancy and lactation periods. The offspring from experimental and control animals have been studied on days 3, 7, 14, 21 and 30 days after birth using morphology, electron microscopy, immunohistochemistry and biochemistry methods. In was shown, that the toxic effect of pesticide exposure through the maternal organism during pregnancy and lactation is manifested in the form of a violation of the growth and formation of the thymus, as well as thymus-dependent zones of the peripheral organs of the immune system. In the mechanism of immunotoxic effect of pesticides a leading role plays the imbalance between proliferation and cells apoptosis of the thymus, caused both by direct toxic effects of drugs, and by the development of hypothyroidism and oxidative stress
Young apple trees that are planted in areas with limited water resources face challenges in their early growth stages. Insufficient intake of moisture often stunts the growth of the young tree and impacts its subsequent growth. In this study, we observed the interaction of semi-vigorous Marubakaido (Ma) (Malus prunifolia
„Ringo‟) and dwarfing Jm7 („Marubakaido‟ × M.9) rootstocks, water treatments (50% and 70% soil water content) and soil treatments (water retention substances) on young „Miyabi Fuji‟ apple trees and how this interaction impacts their growth under dry climactic conditions. The development of shoots, stems and roots was analyzed. The results showed that the interaction of rootstock and water and soil treatments had
a significant impact on total shoot length (p < 0.01), as did the interaction of rootstock and soil treatment on the length of the top three shoots (p< 0.05) and trunk fresh weight (p < 0.05). In addition, it was found that the interaction of water and soil treatments impacted shoot fresh weight (p < 0.05). This study revealed that the growth of young apple trees in areas with limited water resources can be aided by providing a 70% and 50% saturation of water and soil retention treatments for young trees that have been grafted onto semi-vigorous Ma and dwarfing Jm7 rootstocks. Growers in these areas should think about which rootstock to use, what soil water retention treatments that can be introduced into the soil as well the amount of water that should be applied.
The given study focuses attention on the essence of creating a
motivational environment while the teaching of English language for medical students as well as the improvement of modern methods and skills and their effective use. Besides, the influence of motivation on the successful acquisition of English, the impact of the most frequent motivational moments on medical students are analyzed. Some effective methods are proposed to create favorable conditions for students to learn the language, achieve effective results, and self-government in this regard. The development of motivational forms aimed at improving knowledge and skills of English in the training of personnel for the medical field is interpreted as much as possible in the organization of study strategies and effective curricula.
The present article seeks to explain the impact of the processes globalization on national cultures and the response of ethnic cultures to such processes from the viewpoint of alternate progress theories. The immanent connection between globalization and ethno-cultural diversity, proximity and national-cultural models of alternative development are the object of our research.In the current period, the communicative function of culture has expanded dramatically, transformation processes are taking place in it in accordance with global changes. In particular, forms of indirect communication (mobile phone, Internet) are making radical changes in this function. Now there is rapid rapprochement of cultures, exchange of experience and mutual enrichment. At the same time, it is necessary that the communicative function does not harm the diversity of ethno-cultures, does not interfere with intercultural communication in accordance with national interests, and especially does not focus on the decision-making of Western popular culture. No matter how much international dialogue and integration help to establish universal values and norms, they should not serve to make a culture in a mood of expansion become a dominant force.During the period of democratic reforms, scientific and practical research was started on the restoration of Uzbek ethnic culture, the use of its historical, educational and artistic-aesthetic possibilities. The state is leading the development of many types of folk creativity and art. However, comprehensive research of Uzbek ethnic culture, its genesis, sociological and axeological foundations, integration relations with the culture of sister nations, and comparison with other ethnic cultures in the system of these relations is one of the tasks before us. Philosophical studies conducted today are mainly empirical in nature, philosophical generalizations are rare in them. Therefore, there is a scientific-theoretical need to study cooperation, communication and integration between ethnic cultures under the influence of globalization from a philosophical point of view, without forgetting the allogenesis and ideogenesis of ethnic culture. It should focus not only on making philosophical generalizations, but also on finding ways to effectively use artistic-aesthetic possibilities, tools, and artifacts.
This article examines the influence of Karl Popper's views on postpositivism, and explains how Popper's views are related to the ideas of positivism, neopositivism, and formed as an idea that complements the above teachings from the point of view of historical development. The role and importance of Popper's views in modern philosophy and the attitude towards him in his time are analyzed.
The thyroid gland of posterity, got from full-grown with chronic intoxication by pesticides, have been studied on 1-90 day after birth using electron microscopy methods. It is revealed that intoxication of maternal organism vastly slows the rates of postnatal formation of secretory follicles. It is expected that discovered ultrastructural changes of the thyrocytes are morphological substratum of the dysfunctions of the thyroid gland.
Alkogolni salbiy ta'siri va kontiniumni kuchaytirishi
fanda yetarlicha isbotlangan yoki o'rganilgan. Lekin
giyohvandlar populyasiyasida bunday vazifani qo'yib
bajariigan tadqiqotlar juda kam, O'zbekistonning Farg'ona
vodiysida esa - yo'q darajada. Shu bois, giyohvandlikka
berilgan aholi guruhlarida alkogolni xatarli omil sifatida
epidemiologik tavsifi o'rganilib chiqildi va amaliyot
uchun ahamiyatli natijalar olindi
The current examination expects to analyze the concern that pedant occurrence in commanding of illuminate investigation compute, to uncover the motivation of the concern and to create arrangement proposals. Contextual investigation plan of subjective examination techniques was utilized in this exploration and it incorporates 41 volunteer pedant. Organized meeting structure was utilized in information assortment and the information were examined with content examination. It was discovered that the majority of the concern pedant occurrence in commanding of educating investigation compute were identified with understudies. They likewise had concern with study hall/course the board. In commanding of illuminate investigation cycles of the pedant, concern were identified with understudies, actual foundation, instructive framework and society/climate. It very well may be stated that a large portion of the concern can be settled if their motivation are resolved and taken care of. Likewise it is proposed that approaching pedant who are new to scholastic life need to follow the guidelines that incorporates understudy discipline guidelines and the understudies should be educated about the negative practices and their results toward the start of the term.