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No. 2 (2018) Doctor’s herald
No. 2 (2018) Doctor’s herald
Journal:
Doctor's Herald
Published:
2022-03-30
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Статьи
Nephropathy of metabolic genesis in young children: Assessment of partial renal function
121 children with pneumonia on dismctabolic nephroparthy background were investigated, and 20 children with pneumonia wittout urinary syndrome. It were performed following methods of kidney partial functions investigation of glomerulus filtration, ammonia, acidity, osmotic quality of urine, daily metabolites screening (oxalates, urates, urine acid). In patients with pneumonia on dismetabolic nephroparthy background were revealed significant alterations of kidney partial functions, stnictural and functional condition of erythrocytes membrane, increasing of peroxides lipid oxidation processes. For the purpose of correction children with pneumonia and renal pathology it was prescribed following treatment.
М Akhmedova, R Sharipov, N Rasulova, Z Makhmudova
12-15
757
12
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Resection of small intestine in patients with acute obstruction of gastrointestinal tract. Complications and prevention
The purpose of the work is to study the causes of complications after resection of small intestine in patients with its acute obstruction and to develop possible methods for their prevention, which will improve the results of surgical treatment of such patients. In 19 patients (4,1%) from 221 operated patients, resection of the intestine with anastomosis was performed. The degree of severity of intoxication syndrome, non-specific resistance of an organism, terms of recovery of motor-evacuation function of small intestine, comorbidity index, degree of surgical and anesthetic risk on the ASA scale have been studied. Retrospective analysis was performed in 15 patients with adverse treatment outcomes. Possible causes of the complicated course of the postoperative period are highlighted. A method of enterostomy for decompression of the digestive tract in patients with acute obstruction of the small intestine and medication stimulation of the small intestine motility in the postoperative period is suggested, which helps prevent the development of intestinal motility disorders and improve the quality of life of patients after the operation.
V
20-24
35
8
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The role of indicators of cytokins and markers of inflammation In development of complications in acute inflammatory diseases of upper respiratory ways in children
Based on a survey of 167 children with acute inflammation of the upper respiratory tract, the features of the cytokine status in children with acute inflammatory diseases of the respiratory system were identified, which were expressed in the activation of IL-1, IL-8 and TNF-a, depending on the development of the inflammatory process. The relationship between changes in traditional clinico-laboratory indicators for acute inflammatory diseases of the respiratory system that determine the severity of the disease and changes in levels of markers of inflammation, in particular C-reactive protein, is established.
A Zufarov
29-32
69
6
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Influence of mother's preeklampsy on the state of newborns
The state of 65 newborns born from mothers who had prceclampsia and from a physiologically occurring pregnancy was studied. It was found that the preeclampsia of the mother significantly affects the health of the newborn and leads to a greater frequency in the CNS lesion, while in the group of children bom to mothers with preeclampsia, more severe syndromes of the CNS are noted.
G Islomova, Z Safoyeva, М
37-40
46
12
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The role of ultrasound method of diagnostics for monitoring of efficiency of neoadjuvant mammary gland cancer chemotherapy
Samarkand Branch of the Republic Specialized Scientific-Practical Medical Centre of Oncology and Radiology Nowadays mammary gland cancer takes one of the first places in the structure of morbidity and is an actual problem in oncology. In this work the meaning of USD scanning for monitoring of efficiency of neoadjuvant mammary gland cancer chemotherapy is examined.
М Karimova, А Akramov, О, N Achilov
44-46
170
9
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The prevalence of neurocirculatory dystonia in hiv-infected population as a function of the marital status, an accessory to the ethnical and religious group
An analysis of the prevalence of NDCs in the HIV infected population of Fergana has been performed, depending on the age, marital status, as well as belonging to the ethnic and religious group. It is a comprehensive assessment of the unique nature of the course of the disease in patients of different sex and age, as well as with different marital status, enabling the doctor to improve early diagnosis and prevention, for further planning an individual approach to treatment.
N Mamasaliev, М Ibragimov, Z Mamasaliev, U Suvonkulov
50-54
42
4
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Epidemiological-clinical peculiarities of comorbid pathology in hiv infected patients with neurocirculatory dystonia
The research, which we conducted, is based on an epidemiological analysis of the results of a questionnaire of 341 HIV-infected persons with NCDs. This study was conducted using specially developed questionnaires, as well as instrumental diagnostic methods. The results of the research showed that the clinical diagnosis of NCDs in HIV-infected patients with comorbid pathology is a big challenge. In turn, this indicates the importance of carrying out complex instrumental and special diagnostic methods for patients in this group.
N Mamasaliev, М Ibragimov, Z Mamasaliev, U Suvonkulov
59-62
163
7
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Determination of level 25 (oh)d3 in serum and its effect on the prevention of rickets
In the article, data on the effect of prophylaxis of rickets in children at level 25 (OH)D in serum in Uzbekistan arc considered. Proper use of vitamin D can reduce severe forms of rickets, improve the child’s psychomotor development.
N Rasulova, А Rasulov, R Sharipov, М Akhmedova, L Irbutaeva
72-75
35
10
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Symptomatic myoma of uterus and differentiated approach in its treatment
Today a modern woman wishes to give birth at a sufficiently mature age, pre-planning the number of children, unfortunately often at this age is found out uterine myoma. Established fact, negative affection of both submucous and intramural nodes on the ability to conceive and safe bearing of pregnancy. In our study were women of different ages symptomatic uterine fibroids which was recommended for hysterectomy surgery and which was previously as pre-opcrative preparation to prescribe the drug ulipristal acctat in the from of a course of treatment.
N Saparbayeva
85-84
41
5
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Risk factors of geneur lesions of the spinal brain and shoulder splitting
This article describes the risk factors for the development of spinal cord injuries accompanied by obstetric paralysis of various types. We examined 80 children with consequences of a combined trauma of the spinal cord and brachial plexus, which were divided into 2 groups. Results of a research have shown that in origin of the combined patrimonial damages of a spinal cord and a humeral texture the set of pathological factors matters.
S Umirova, А Gaybiev
89-91
20
7
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Features of hormonal status and mineral exchange in juvenile rheumatoid arthritis in children with different forms of the current
This article presents the results of a comprehensive examination of 55 patients with juvenile rheumatoid arthritis. This type of children has desynchronization in the endocrine system, which is manifested in the increase of thyroid hormones, and the severity of the disturbances depends on the form, the expressed activity and the duration of the disease. There were changes in the parameters of the structural and functional state of bone tissue in children suffering from JRA, which manifested itself in the form of osteoporosis or osteopenia of varying severity.
E Shamansurova, U Rahimgaziev
97-101
87
20
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Content of volatile fatty acids in biological media in babies with sepisis
In babies with sepsis, there is a change in the quantitative and qualitative composition of the microbiota, manifested by an increase in the feces of oil and propionic acids, which indicates the activation of opportunistic flora and severe anaerobes. The displacement of the aerobic index in the region of sharply negative values and a sharp increase in the ratio of the level of iso-acids and the ratio of isovaleric acid to valeric acid, indicates an increase in the activity of aerobic microflora with proteolytic activity in the lumen of the intestine in patients with sepsis. The increase in agglomeration properties of leukocytes is associated with an increase in the content of butyric acid in the blood of patients with sepsis.
A Shamsiev, A Alimov, D Rabbimova
107-110
29
3
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Application of medical physical training for children сerebral palsy in home conditions
The aim: to study the role of physical culture in children's cerebral palsc. Materials and methods of research. We examined 84 sick children with cerebral palsc. All the sick children were divided info two groups: basic and control. In addition to standard therapy, the children of the main group were also added therapeutic physical skills at home. Results. The children of the main group became healthier, moral values were formed, and skills of independent activity were formed. Conclusion. Therapeutic physical training at home should be an essential part of the treatment for infantile cerebral palsy.
М Egamova, Z Mavlyanova, G Burhanova
114-117
72
9
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Gigantic lymphoma of mammary gland
The analysis of the clinical case examined in Samarkand Branch of the Republic Specialized Scientific-Practical Medical Centre of Oncology and Radiology is assumed as a basis of this work. The methods of diagnostics and the scheme of treatment of the patient with gigantic non-Hodgkin's lymphoma of the right mammary gland (extranodal) with affection of tonsil and spleen concomitant viral hepatitis in stage III A were described.
М, D Rakhmatov, M Abdukhalilov, D Tugizova, N Achilov
123-126
30
5
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Cesarean section after metroplasty
The most common causes of metroplasty are a two-horned uterus and the presence of a septum in its cavity. Among all women, such congenital pathologies occur in 2-3%, and among women with repeated miscarriages — in about 15% and with infertility—in 14%. Cesarean section after metroplasty with abnormalities of uterine development is the most acceptable method of delivery, due to the presence of many complications of the course of labor.
B Negmadzhanov, F Ganiyev, М Mamatkulova, V Kim
130-132
36
9
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Analysis of the autodestructive behavior of depressive genesis in adolescents
Article presents the experience of analysis of the self-destructive behaviors in adolescents revealed that adolescents often observed demonstratively-blackmailing suicidal behavior, emerging against the background of depressive affect, as a result of intrapersonal conflicts and are mainly a problem of behavioral and stress-related disorders, occur against a background of non-psychotic level of psychopathological conditions. The study of clinical features of selfdestructive actions in adolescents with behavioral disorders depressive register reveals the risk for suicidal willingness among this group of patient.
V Abdullayeva, S Babarakhimova
7-11
60
24
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Some morphofunctional changes of heart at the influence of pesticides
In our work, we identified morphological and functional changes in the heart in an experimental model of toxic myocarditis with exposure to pesticides who went through the mother's milk. Based on the results of the study found out when exposed to pesticides in the experimental groups in the early stages there are certain disorders of the myocardium and blood vessels. These changes arc confirmed violations of the functional parameters of the heart changes.
S Akhmedova, U Mirsharapov
16-19
17
8
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Evaluation of physical working capacity of young athletes with increased рhysical exertion
We carried out a comparative evaluation of physical working capacity according to the results of the Harvard step-test of 100 young athletes and 20 children and adolescents who are not involved in sports.
G Burkhanova, О Kim
25-28
48
11
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The use of immunocorrective therapy for the treatment and prevention of diseases in children who are often ill
The problem of chronically ill children is one of the most urgent and unsolved problems in pediatrics. We identified specific abnormalities in certain parts of the immune system and non-specific defense of the organism in FIC, which is the basis for inclusion immunocorrective drugs for the treatment and prevention of diseases. Use as drug immunocorrective Broncho-Munal reduces the incident of disease and improve quality of life of ill children.
L Irbutaeva, R Sharipov, A Rasulov, N Rasulova, M Akhmedova
33-36
100
26
Read
Frequency and structure of non-esophageal manifestations of gastroesophagal reflux disease
Among all the patients examined, the course of gastroesophageal reflux disease is associated with diseases of other organs and systems of the upper respiratory tract (67.2%), including otorhinolaryngological manifestations (63.2%), bronchial asthma (53.1%), non-congenital pain syndrome thorax (61.3%). Based on the data obtained, a close relationship between GERD and the possibility of the development of chronic pathology of bronchopulmonary system (bronchial asthma) and upper respiratory tract (chronic pharyngitis) has been proved.
S Kaleda
41-43
36
6
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Evaluation of the effectiveness of physiotherapeutic treatment at the craniocervicalgia
Complication of the pathogenesis of cranioccrvicalgia and clinical polymorphism of the complex of symptoms reveals the need for a systematic approach to restoring healing procedures. The effectiveness of physiotherapy treatment in patients aged 18-35 years with craniocervicalgia was evaluated. Pathogenetic orientation and high efficiency of complex physiotherapeutic treatment were determined.
Z Mavlyanova, М Abdusalomova, Sh Sabirova
47-49
71
12
Read
Epidemiological model and algorithms of prevention Of neurocyryculatory dystony in hiv-infected population under the conditions of the fergana valley of uzbekistan
In the course of the epidemiological research, were identified 18 major risk factors in the formation of NCDs among the HIV-infected population. Based on the data obtained, was developed an algorithm for the early detection and prevention of NCD in an HIV-infected population of the Fergana Valley of Uzbekistan.
N Mamasaliev, М Ibragimov, Z Mamasaliev, U Suvonkulov
55-58
63
7
Read
Diagnostic effectiveness of visualization methods of renal cell Carcinoma according to the surgical intervention`s data
Aim of the research: According to the comparison of data of ultrasound diagnosis and computer tomography with the results of intraoperational findings and histology research; the sensibility degree, specific and effectiveness of that methods should be identified with the assessment of renal carcinomas local dispersion for each given research methods. Materials and methods: The results of examination and therapy of 170 patients who suffered from renal cell carcinoma were addressed to the urology department of Republican Center of Oncology and to the Republican Center of Urology from the 2010 till the 2015 constitute the basis for the given research. It is worth mentioning that 104 of patients were males (61,2%), whereas the number of females were just 66 (38,8%). The age of patients fluctuated from 22 until 83 years old, the average age was 57,5±6,8. Results: The given data about the assessment of the results of renal carcinoma patients' ultrasound diagnostic showed that the sensibility of USS during the identification of the T1 stage constitute 66,7%, while the figure for T2, T3 and T4 is 68,9%, 83,3% and 100% respectively. As regard the specificity of USS during identification of the T1 stage is 100%, this ratio is 95,7% for T2, 96,5% for T3 and 97,1% for T4. The diagnostic accuracy of the USS in the determination of T1 stage is 94,2%, T2-80.8%T3-94,2%T4-97,l%. The tomography's results of the patients who suffer from renal carcinoma showed that the sensibility rate during the determination of the T1 stage is 90%, T2-97,5%, T3 and T4 - 100%. Specificity of tomography in the determination of T1 and T2 stages is 100%, T3-87,3% and T4-88,5%. The diagnostic accuracy of tomography in the determination of T1 stage is 87,6%, T2-98,9%, T3-89,9% and T4- 88.8%. Conclusion: The obtained results of the research showed that inclusion of modern diagnostic methods such as ultrasound, X-ray, tomography into complex plan of the patients' examination who suffer from renal cell carcinoma allows to determine quite effectively the degree of cancer prevalence and distinguish local cancer from primarily-generalized tumor forms. This improvement, in turn, affects the tactic of treating this category of patients.
D Nizamov, N Rakhimov
63-71
34
6
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Results of modified surgical access to regional lymph nodes in the treatment of renal cancer
Purpose: To study the long-term results of a new method of surgical access to the main vessels and regional renal cancer lymphocollectors. Materials and methods: In the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology, as well as in its Tashkent City Branch from 2010-2015, 96 patients were treated. The distribution of patients by sex and age intervals is shown in the figure. There male predominance 51 (53.1%) versus 45 (46.9%) women, the ratio was 1.1: 1. The age range is from 21 to 75 years, the average age of patients was 56.0 ± 1.3 years. From 96 patients participating in the study, a tumor process was established in 51 (53.1%) men and 45 (46.9%) women. The number of patients with metastatic lesion of regional lymph nodes were followings: N1 - 10 (10.5%), N2-6 (6.2%). In the remaining 80 (83.3%) patients, regional lymph nodes were intact. All patients underwent radical-extended nephrectomy. After laparotomy, the ascending and transversely dividing colon of the large intestine is mobilized, the loops of the intestines are pulled back with a moist towel up and to the left. After this, the back of the peritoneum is opened over the projection of the aorta from the level of the aortic bifurcation, the top with the dissection of the triceal ligament is opened beyond the peritoneal space. Results: The character of the histological form of the kidney tumors established after the operation by morphological examination were followings: the clear cell cancer in 77 (80.2%), papillary cancer in 8 (8.3%), unclassifiablc cancer in 4 (4.2% ), chromophobic cancer - in 7 (7.3%). At stage 1, no metastasis was detected. In stage 2 metastasis was noted in 4.2% of cases. In stage 3, 18.0% metastasis was detected. In 27.3% of patients metastasis took place in the 4th stage. All 13 patients (13.5%) had postoperative progression of the disease revealed. Conclusion: In renal tumors with Ti, we recommend performing selective lymphodisection, that is removing of first-order lymph nodes for precise staging. For T2.4N0.2M0 tumors, it is recommended to perform an extended lymph dissection from the level of the diaphragm legs to the aortic bifurcation. The development of surgical access with a cut of the triceal ligament with extended lymph node dissection of the renal cancer and a small number of postoperative complications make it possible to apply it in all patients with renal cancer.
N Rakhimov
76-81
28
6
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Comorbid flow of gout and metabolic syndrome
In 49 patients (mean age - 50.6 ± 1.6 years, duration of disease - 9.4 ± 1.7 years) male gout were investigated anthropometric data, lipid profile, depending on the extent of the clinical and laboratory parameters. It has been established that the basic 3 clinical factors of the metabolic syndrome - obesity, hypertension, diabetes mellitus occurs in 49.3% of patients with gout. Dislipedemiya, hypercholesterolemia and increase in low density lipoprotein and very low density detected in 60,0-67,3% cases. In patients with urolithiasis frequency, severity of the violation rate of lower limb function, the number of affected joints, the number of subcutaneous tophi, arthritis incidence in the last year, the duration of the latest exacerbation and severity of gout own index higher than that of patients without metabolic syndrome. The degree of hyperuricemia and duration of the disease have a direct correlation with the degree of increase of total lipids and cholesterol in the blood serum.
D Toirov, I Sultonov
85-88
111
12
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