Изучить клинико-неврологических проявлений детского аутизма.
Any epidemic and pandemic that is a great stress or emergency leads to disruptions in the psycho-neurological system and human behavior. Psycho-emotional excitement in patients with severe Covid-19 dramatically reduces the effectiveness of non-invasive ventilation. Purpose of the study: to assess the efficacy, safety and impact on the quality of life of patients with dexmedetomidine and propofol against the background of a decrease in need for oxygen. The study included 21 patients with severe and extremely severe Covid-19. In the first group of patients with fear of death, a combination of drugs propofol + sibazone + fentanyl was used. In the second group, dexmedetomidine and promedol. Conclusions: in patients with a severe course of coronavirus infection, dexmedetomidine is more effective in reducing psycho neurological arousal and improving cognitive functions, which leads to an effective supply of oxygen and to their faster recovery.
Проблема задержки внутриутробного роста и развития плода (ЗВУР) остается одной из актуальных в современном акушерстве и перинатологии.
The review article considers the issues of dementia and the need for research on cognitive decline in Central Asian countries. The paper presents the results of experimental and clinical studies of liposomes, which are a product of nanotechnology, which make it possible to assess the prospects for the therapeutic potential in many neurological disorders, including dementia
Any pathological mechanisms are triggered by various etiological factors or biological events, therefore a large number of neurological diseases, especially of ischemic origin, with different evolution (acute, chronic) are degenerative and are reflected in the state of other vital organs [1 ,6]. The main task of eliminating cerebral ischemic catastrophes is to block ongoing pathogenetic processes in the shortest possible time, in order to maximally limit the penumbra zone in order to avoid massive death of brain cells [5, 11].
У детей одним из наиболее частых неврологических синдромов после ЧМТ является хроническая посттравматическая головная боль. Выделение хронической посттравматической головной боли (ХПТГБ) в Международной классификации болезней 10 пересмотра из общего класса посттравматических расстройств отражает современную тенденцию к выделению отдельных нозологических синдромов для разработки дифференцированных стандартов лечения и свидетельствует об актуальности проблемы.
Изучить особенности неврологических нарушений у детей с аутизмом.
BACKGROUND: Sepsis is one of the leading causes of hospital mortality in children. a decisive role in improving the results of treatment of this group of patients belongs to early diagnosis and pathogenetic therapy. AIM: this study optimizes the diagnosis and intensive care of surgical sepsis in children based on clinical and laboratory criteria and bacteriological monitoring.
MATERIALS AND METHODS: the study period is 2018–2020. the study subjects were children (n = 73) with surgical pathology (diffuse purulent peritonitis, bacterial destruction of the lungs, post-traumatic brain hematomas, injuries of the abdominal organs, and others). clinical and laboratory parameters were analyzed, and microbiological monitoring was performed to determine antibiotic sensitivity.
RESULTS: Patients who developed sepsis had a pronounced hypermetabolic syndrome, which was manifested by tachycardia and tachypnea, hyperthermia, low levels of albumin, and total protein in the blood. Protein catabolism in patients was accompanied by a decrease in globulins (IgG) synthesis and the development of a secondary immunodeficiency state. Both gram-positive and gram-negative microorganisms were involved in developing surgical sepsis in children, increasing the proportion of the latter. Given the high proportion of multi-resistant flora, empirical combined de-escalation antibiotic therapy (aBt) with broad-spectrum antibiotics was prescribed. this was followed by its revision based on microbiological monitoring and clinical and laboratory data of the patient with sepsis. Studies have shown the effectiveness of complex intensive care in 86.3% of cases. Mortality occurred in 13.7% of cases. Patients with severe surgical pathology died: fecal, generalized peritonitis, severe traumatic brain injury + coma with irreversible neurological disorders, and urosepsis against the background of chronic renal failure after repeated surgical interventions.
CONCLUSIONS: early diagnosis of sepsis, rational aBt under the control of microbiological monitoring, non-aggressive infusion therapy, and active sanitation of the surgical infection focus contributed to a decrease in mortality in this category of patients.
The relevance of CVD (Cerebrovascular Diseases), in particular strokes, is due to the high prevalence, disability and mortality.
The degree of medical, social, psychological rehabilitation of patients after Ischemic Stroke depends on the regression of the clinical picture and cerebral disintegration.
Objectives of the study: detection of the entire spectrum of clinical manifestations from examined patients, corresponding to damage to the structures of the brain supplied by the vessels of the Vertebrobasilar basin, the relationship with regression of the primary focus and the subtype of Ischemic Stroke, and determination of the presence of a statistically significant dependence of clinical manifestations on COPD.
To achieve the goal and solve the set tasks, 126 patients, 60 men and 66 women were examined in the recovery period of stroke in the in the vertebro-basillar system, at the age of 50-80. The Blindemark scale was used to assess the neurological status. To assess neuropsychological status, the Montreal Cognitive Assessment Scale, the Hospital Anxiety and Depression Scale, the Rankin scale were used, as well as for objectification of MRI data and Dopplerography.
Results of the study: In patients with Ischemic Stroke in the vertebro-basillar system, paresis and paralysis prevailed in the structure of clinical manifestations, 68 patients had them, which is 54%, 43.7% of patients had dysarthria, coordination disorders were observed in 48.4% of patients, 26.2% had vertigo, 24.6% had sensory impairments and 5.6% had neglect.
In patients with Ischemic Stroke in the vertebro-basillar system, a correlation was found between the scores of Renkin scale. Various pathogenetic subtypes of ischemic stroke in vertebro-basillar system were analyzed. They have a significant correlation between NIHSS scores at the time of hospitalization and at the end of rehabilitation. In patients with AT Ischemic Stroke in the vertebro-basillar system the incidence of oculomotor disorders is significantly lower. Based on the above mentioned, the following conclusions can be drawn:
1. A certain localization of the focus of ischemic stroke in the vertebra-basilar system is more likely to be characteristic of the corresponding stroke subtype.
2. The rate of reduction and reorganization of the focus does not depend on the stroke subtype, localization of the hearth, comorbidphone, rehabilitation methods and is proportional to the initial size of the heart attack site.
3. The degree of severity of COPD has a correlation with the blood flow indices of posterior cerebral arteries and vertebral arteries, as well as the asymmetry coefficient.
The brain organic defect, which forms the basis of cerebral palsy, occurs early, during the incomplete process of formation of the main structures and mechanisms of the brain, which causes a complex combined structure of neurological and mental disorders. The degree of mental disorders varies from mild disorders in the emotional sphere to severe intellectual underdevelopment. The peculiar- ity of mental development in cerebral palsy is not only its slow pace, but also its uneven nature. In recent years, microcurrent reflexo - therapy (MTRT) has been widely used to correct motor and coordination disorders in this group of patients.
Cardiovascular pathology and acute cerebrovascular accident (ACV) are in first and second place, respectively, as the causes of mortality in the structure of general mortality of the population. In this regard, interest in the issues of cerebral blood flow disorders does not weaken all over the world, more and more new aspects of this problem are being considered. CVA is a widespread pathology in the world and according to the WHO “... about 17.5 million people die every year from cerebrovascular diseases in the world, which is 30% of mortality from all diseases ...”. The most severe form of vascular pathology of the brain is a stroke. In European countries, mortality from stroke varies from 63.5 to 273.4 people per 100,000 population per year. About 85-88% of cerebral strokes are ischemic in nature. Ischemic stroke in developed countries ranks first as a cause of permanent disability. Movement disorders of varying severity are the most common and severe consequences of strokes.
Изучить особенности клинического течения параноидной шизофрении, сочетанной с хроническими соматическими заболеваниями.
In patients with radiculopathies of various origins, along with chronic pain syndrome, various prolapse of the pyramidal sphere of the peripheral nervous system is observed [1]. In groups of patients with radiculopathies, the motor sphere was investigated using the described methods of studying the neurological status Skoromets A. A, which revealed a statistically significant limitation of the motor sphere [2]. The performed electroneuromyography confirmed the lesion in the motor fibers in patients with chronic pain syndrome with radiculopathies of various origins [4].
Определить уровень тревожности у мужчин, состоящих в бесплодном браке.