All articles - Pediatrics
Number of articles: 1393
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The etiology, pathogenesis, individual characteristics and pathophysiology of the meconium aspiration syndrome have been studied based on foreign and domestic literature. All kinds of diagnostic and preventive methods were fully considered. -
Evaluation of perinatal death cases and the level and status of ear, throat and nose diseases in themThe study examined the prevalence and causes of perinatal death in Khorezm region and the causes of infant mortality at 22 weeks and 7 days of gestation, as well as changes in the ear, throat, and nose. In the city of Urgench, Khorezm region, the birth rate was higher than in other districts, and in the course of inspections, the highest number of deaths was caused by upper respirator}* diseases.
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The aim of the study was to study the risk factors for congenital heart defects in newborns. 374 newborns with congenital heart defects were examined. When determining the significance, according to the questionnaire with a codifier of 42 features, modifying risk factors for the development of congenital heart defects were identified by socio-hygienic, medico-biological, the influence of intrauterine infections, taking medications by the mother during pregnancy, and obstetric and gynecological indicators. -
A total of 50 patients who were diagnosed with allergic rhinitis were inclu-ded in the study. Patients were categorized into two groups: as having intermittent (34%) and perennial (66%) rhinitis. All patients were given conservative treatment to facilitate symptom impairment and prolonged remission. -
DIAGNOSTIC VALUE OF CYTOKINE PARAMETERS IN SYSTEMIC INFLAMMATORY RESPONSE SYNDROME IN NEWBORNSThe authors conducted a study on the cytokine status of newborns with perinatal infectionsand non infec-tionsdisease in newborns. It was found that newborns with intrauterine infections arc characterized by high levels of IL-6. IL-8 TNF-a in venous blood. IFN-y and IL-6 are prognostic markers for newborns with perinatal pathology of non-infectious origin. Simultaneous increase in their concentration indicates an unfavorable outcome.
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PATHOGENETIC SIGNIFICANCE OF POLYMORFHIC GENES OF MATRIX METALLOPROTEINASES AND THEIR TISSUE INHIBITORS IN THE DEVELOPMENT OF CHRONIC GLOMERULONEPHRITIS IN CHILDRENThe incidence of chronic glomerulonephritis has been steadily progressing over the past 10 years and accounts for 36.76% of all diseases of the kidneys Diseases of the urinary system, according to WHO, currently occupy the 2nd place among the main forms of renal pathology characteristic of childhood. In the structure of kidney diseases in children hospitalized in the nephrological department, glomerulonephritis occupies the second place [I]. The urgency of the problem of chronic glomerulonephritis is explained not by the prevalence of the disease, but by the course of the disease and the development of renal failure [2J. Chronic glomerulonephritis is one of the severe kidney diseases in children, which is characterized by the frequent development of complications and progression of the disease.
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THE ROLE OF GENES-MEDIATORS OF IMMUNE INFLAMMATION IN DESTRUCTIVE- INFLAMMATORY DISEASES OF THE GASTRODUODENAL REGION IN CHILDRENA significant contribution to the development of gastroduodenal pathology is made by a violation of the functional activity of the immune system, implemented by T- and B-lymphocytes, in particular, cytokines. This is determined by the pleiotropy of cytokine effects and consists in the regulation of proliferation, differentiation and modulation of apoptotic cell death. The cytokine system includes about 200 individual polypeptide substances, among which are interleukins (IL) 1-37; interferons (INF) a, p and y; tumor necrosis factors (TNF) a and P; colony stimulating factors (CSF); growth factors; chemokines and some others. At the same time, two groups of cytokines are distinguished: anti-inflammatory (IL-l, IL-6, IL-8, IL-12, TNF-a, INF-y), and anti-inflammatory (IL-4, IL-10, IL-13, TGF-P) [5,11,48].
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Thymus is the main secret of medicine (primarily immunology). In the twentieth century, the attitude of scientists to the organ developed as a generator and regulator of immune reactions, a participant in the production of large populations of immunocompetent cells. The thymus is a major component of the immune system and, in many ways, a central organ. Infectious diseases, systemic autoimmune diseases, oncology, the problem of tissue incompatibility determine a person's life, in connection with which there is a growing scientific interest in the study of the immune system and its central organ - the function of the pancreas. The complexity of the study lies in the large number of integral connections with other components of the immune system of the pancreas, neuroendocrine, hematopoietic and connective tissues, organs that provide the barrier function, etc. The interest of pediatricians in this area is associated with a certain understanding of human ontogenesis from birth to old age, where the thymus gland plays an important role in the prenatal and postpartum periods. The purpose of this review is to draw attention to some of the results of inaccurate assessment of functions associated with the diaphragm, its derivatives and the cell membrane. -
CLINICAL MANIFESTATIONS OF GASTROINTESTINAL TRACT DISEASES IN THE ORAL CAVITY IN CHILDREN OF BUKHARAThis article describes changes in the state of the oral cavity at the pathology of the digestive system, shows the main clinical manifestations of these processes and their relationship. The information presented in the work emphasizes the advisability of including the results of a dental examination in a medical record, which will optimize the work of both pediatric dentists and pediatricians.
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The authors conducted a study on the influence of risk factors on the frequency and structure of congenital heart disease in children in the Bukhara region. It was found that the incidence of disease of the cardiovascular system is 6,42 cases for every 1000 births, 6 times more common in children living in niral conditions. Analysis of cities and districts of Bukhara region showed that congenital heart disease is more common in industrialized regions of the region. -
AGE FEATURES OF ANTHROPOMETRIC INDICATORS IN CHILDREN WITH ARTIFICIAL AND NATURAL FEEDINGAnnotation: The study of the growth, development and condition of the facial skeleton of a modem child can be the theoretical and methodological basis for the development and improvement of anthropometric methods of diagnosis and rcconstniction in medicine, the substantiation of new principles for the prevention and treatment of vertebral abnormalities and trauma diseases. In the modern concept of orthopedic treatment, the main task is to achieve the desired results, taking into account individuality.
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TO STUDY THE PREVALENCE OF DENTOFACIAL ANOMALIES AND DEFORMITIES IN SCHOOLCHILDREN IN THE CITY OF BUKHARASummary: In 2018-2019. Between ages 6 to 18. there are 642 schoolchildren living in the city of Bukhara, den-tofacial anomalies and deformations, as well as the spread of temporomandibular diseases caused by them, were identified. Maxillofacial anomalies and deformations were observed among children in Bukhara city with a frequency of 57.5%. of which 36.4% were dentomaxillary anomalies. About 642 children were observed and 298 of them were revealed with bad habits, including 52 (8.1%) children with respiratory failure (from mouth) and 67 (10.4%) children with impaired pronunciation.
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Blood pressure studied on 250 school children. It was found that clearly insufficient attention is paid to the early detection of hypertension and the identification of risk factors. It was found that for the correct diagnosis of arterial hypertension on an outpatient basis, it is necessary to clearly determine the correspondence of actual blood pressure with a value of 95%o for the corresponding sex, age and height. While daily monitoring of blood pressure is the most informative method for the diagnosis of arterial hypertension in pediatrics. -
The article discusses the diagnosis and treatment of urinary incontinence in children. The etiological factors of urinary incontinence in children are considered in detail. Practical recommendations are given to doctors on the choice of approaches to diagnosis and effective medications for treatment and pharmacological methods of therapy. As one of the effective medications for the treatment of monosymptomatic nocturnal urinary incontinence, the drug Driptan (oxybutynin hydrochloride) is recommended. -
THE EFFECTIVENESS OF OXYBRAL IN THE CORRECTION OF LIPID PEROXIDATION DISORDERS IN CHILDREN WITH THE CONSEQUENCES OF PERINATAL DAMAGE TO THE NERVOUS SYSTEMThe results of researches have shown, that at children with prenatal damages CNS reveal significant infringements in processes a lipid peroxidation (LPO), which is possible were characterized as decreasing and in some cases their misbalancc. The assignment of oxibral to children with prenatal damages of CNS alongside with normalization of parameters a LPO to faster improvement of neurological symptoms: children become quiet, active, the dream normalizing. Intra skull pressure on a background of prescription Oxibral was reduced much faster. The opportunity of correction neurological infringements with oxibral opens prospect of rehabilitation and promotes significant to reduction of percent of children with the residual phenomena of prenatal damages CNS.
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CLINICAL AND LABORATORY FEATURES OF THE COURSE OF ENTEROVIRUS ETIOLOGY SEROUS MENINGITIS IN CHILDRENThis article examines an examination of 16 patients aged 1 to 14 years with a laboratory confirmed (cerebrospinal fluid PChR) diagnosis of enterovirus meningitis. All patients, depending on age, were divided into 3 groups. The main group of cases was made up of school children. The course of the disease in all cases is benign with a short febrile period, a short period of clinically pronounced meningeal syndrom.
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Meaning oi dental disease on the background of somatic pathology in the scientific and practice medicine is defined by growth of their prevalence in the general population, the rapid development of complications and the need for a comprehensive approach to treatment by reference to the background therapy. Among 157 children and adolescents with rheumatism living in various regions of Bukhara, a study was made of the particular biophysical properties of oral fluid. An analysis of the results showed a decrease in the rate of saliva secretion (RSS) compared with a healthy group of children and the need to study the level of dental health taking into account the duration and form of rheumatism, basic therapy of background pathology, as well as the development of a set of dental treatment and prophylactic measures taking into account unified protocols for medical helping children with rheumatism. -
This article discusses the age-related features of the functional and physical development of young athletes involved in football and martial arts. The study involved 60 athletes (30 athletes involved in football and 30 athletes involved in martial arts between the ages of 8-15 years old. Assessment of physical development included the measurement of morphological and functional indicators (body weight, height, waist and hips, body mass indices). The obtained data on age periods are compared, and the effects of various sports on the body of children and adolescents are revealed. -
FREQUENCY OF MEETING ANORECTAL MALFORMATION AT ANTENATAL DIAGNOSTICS IN CHILDREN OF SAMARKAND AND SAMARKAND REGION1 he prevalence ot anorectal malformations ranges from I: JJUO to I: 5000 cases ot live births. With the development of antenatal diagnosis, ultrasound criteria specific to anus atresia are currently being actively discussed. The most affordable and effective method that allows you to establish anorectal malformations during pregnancy is ultrasound of the fetus. According to the approved protocol, when a fetus reveals sonographic signs of malformation in a screening center, the pregnant woman attaches herself to the department of pregnancy pathology. Screening ultrasound examination of pregnant women was performed at gestational age 20-22 weeks. Thus, antenatal ultrasound performed during gestational periods of 20-22 weeks shows a rather high information content for identifying sonographic signs, especially without fistulous forms of AWP in the fetus with a sensitivity of 57.1%. specificity - 98.8% and overall accuracy - 96.5 %.
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The article is intended for pediatricians, pediatric neurologists and general practitioners. It provides data on the possible causes of convulsive syndrome in children, as well as tactics and the algorithm of management, care for this category of patients by general practitioners. An integrated approach allows for timely and correctly identify of the cause of convulsive activity in children of different ages, based on objective clinical, laboratory and instrumental (EEG. CT, MRI, etc.) research methods. -
PERINATAL DAMAGES OF THE CENTRAL NERVOUS SYSTEM AND THEIR CONSEQUENCES (REVIEW OF LITERATURE ON EPIDEMIOLOGY, CLASSIFICATION AND TERMINOLOGY)Hypoxic-ischemic lesions of the central nervous system (CNS) in the perinatal period (synonyms - perinatal asphyxia, hypoxic-ischemic encephalopathy, congenital craniocerebral trauma) are characterized by symptoms of secondary ischemia of the nervous system, which develop as a result of chronic or utkir hypoxia (asphyxia) and are confirmed by clinical and laboratory tests. According to the criteria of the organization for the protection of health of the whole world for newly born jackals and births, new cul kilingai with tsgishli for fertility is carried out according to the conditions in the Kui, that is, in the period of 22 weeks the weight of the child should be at least 500 gr or less (with kupson), the height of dirty [2, 4, 5, 19, 22, 23]. The possibilities of living with a child who was born out of wedlock a few decades ago are very rare bulsa, apply now
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Treatment of satanic States depends on the reasons that make it thick. Quickly identify the causes and eliminate it in the uz vaccine allows you to burden some types of satanic cases without uttering an anticonvulsant (anti-Satanic) treatment. Recommended weight loss anticonvulsant therapy should be avoided, both choosing them causes feverish attacks and is prescribed carob in Kharkiv. In the first place, measures to eliminate hypoxia are established. During satiation, the demand for oxygen content increases by 5 times. Therefore, for the first time it is necessary to adequately provide oxygenation of the mine. To do this, the marrow is given with the help of an oxygenated nasal catheter, a enema, a mask, an oxygen chamber, when it is necessary to find (when breathing disorders, satiety attacks last more than 30 minutes), the trachea is intubated. Adskvat oxygen gives the effect of treatment to the bruise burden, it is better to use a transcutaneous monitor (pulsometer) to clarify the vision of the deposit into oxygen. The factors that lead to them in cases of hypoxia in the aloxia, which is accompanied by CyHi-pa metabolic disorders, lead to weight loss. -
Variants of the clinical course of the effects of perinatal hypoxic lesions of the central nervous systemThe objective of this study was to identify variants of the clinical course of central nervous system thera- py. The examined children were divided into groups with coarse focal lesions such as cerebral palsy and chil- dren with elevated functional impairment and minimal brain dysfunction. All children underwent a clinical and neurological examination of the neurophysiological EEG, TCDG. Identified brain immaturity, epileptiform ac- tivity, reduced blood flow to the vessels of the carotid pool
Journal problems of biology and medicine -
Some indicators of phosphorous-calcium exchanges and general condition in children with tubulo-interstitial kidney diseases48 children with secondary pyelonephritis and oxalate nephropathy were studied. A violation of calcium and phosphorus metabolism was revealed. It depended on the presence of risk factors, among which the patho-logical course of pregnancy in the mother, postponed rickets, deficiency of alimentary calcium, and hypodyna-mia are of the greatest importance
Journal problems of biology and medicine -
Efficiency of diagnostic algorithm in children with chronic glomerulonephritis with atopic dermatitisSurveyed 145 children aged 7 to 11 years. Of them: with nephrotic form CGN - 40; CGN on the back-ground of AD-40; AD-40. The control group consisted of -25 healthy children. It was found that in children with nephrotic form of CGN with blood pressure, CGN has a high information content of qualitative and quan-titative signs: oliguria, proteinuria, type 3 diabetes; CGN + BP: edema, total protein, ASL to kidney tissue, CIC; by markers of skin pruritus, IgE. As a diagnostic criterion for the nephrotic form of CGN with AD, there are immunopathological signs: an increase in the renal ASL, CIC, IgE, and overproduction of IL2, IL4. The effectiveness of the use of the diagnostic algorithm in CGN: early detection of GNSS- 35%, HVIN- 65%; CGN + AD: GRNS- 45%, GZNS 55%; AD 20%.
Journal problems of biology and medicine
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