In the introductory part of the article the author characterizes economic attitudes in conditions of market economy. In the basic part of the article the legal status of the microcredit organizations in conditions of market economy is considered.
In the conclusion the author comes to opinion, that it is necessary to develop national norms in sphere of microcrediting in a direction of development of microcredit attitudes.
The article considers the recreational and touristic potential of the region. For the example of the Tashkent region, the possibilities of effective organization of recreational activities with the subsequent impetus for the development of various fields of the service sector are considered. In order to identify opportunities, threats, positive and negative aspects of the region, a SWOT analysis of the recreational and tourist potential of the Chimgan-Charvak resort and recreational zone was carried out. The capacity of the Charvak reservoir zone was considered. As a result of this analysis, problems that were identified associated with negative changes in the ecosystem of the region and assumptions were made about the possibility of reducing the recreational and tourist potential of the Tashkent region. Also, zoning of the mountain and foothill zone of the Tashkent region was carried out. As a result, four functionally different types of mountain recreation areas were identified. The Concept of the prospects for integral development and territorial organization of recreation in the mountainous zone of Uzbekistan is proposed and the basic principles of its functioning are developed.
The article talks about the roads of the city of Samarkand, traffic flows, existing infrastructure and conducts a theoretical analysis. We are also talking about the nature of decisions and regulations on the development of the city of Samarkand, adopted by the President of the Republic of Uzbekistan and the Cabinet of Ministers.
The purpose of the study is to determine the significance of genetic factors in the development of chronic nephritic syndrome in children and to clarify the features of the clinical course
The оbject of research were 129 children aged 4-15 years who were treated for chronic nephritis in the nephrology department of the Samarkand Regional Multidisciplinary Paediatric Medical Centre.
The scientific novelty of the study is as follows:it has been established that the severity of chronic nephritic syndrome in children is associated with clinical manifestations (gradual development, dyspepsia, abdominal pain) and an increase in the amount of Cystatin C in the blood;for the first time, it was revealed that the development of sclerotic lesions due to increased proliferation in patients with the presence of the MMP-9 (A-8202G) rs 11697325 genotypes in chronic nephritic syndrome leads to a worsening of the clinical course of the disease; established early diagnostic marker MMP-9 (A-8202G) rs 11697325 and its tissue inhibitor TIMP-2 (C536T) rs 11551797 in chronic nephritic syndrome in children in the diagnosis of the disease; for the first time, the prognostic value of the alleles of the MMP-9 (A-8202G) rs 11697325 genes and the homozygous G/G genotype in determining the risk of developing the disease in children with chronic nephritic syndrome has been proven.
Implementation of the research results. Based on scientific results of evaluation of the role of polymorphic genes of matrix metalloproteinase and its tissue inhibitors in chronic nephritic syndrome in children: methodological recommendation “The role of polymorphic genes of matrix metalloproteinase and its genetic inhibitors in the development of chronic nephritic syndrome in children” was developed and approved (reference of the Ministry of Health of the Republic of Uzbekistan No. 8n-r / 554 of 30.02.2022).
This methodological recommendation made it possible to predict the development of chronic nephritic syndrome in children and improve preventive measures; approved and developed on the basis of scientific results of research on early diagnosis and prognosis of chronic nephritic syndrome “Dynamics of clinical and laboratory parameters in nephritic syndrome in children”, (reference of the Ministry of Health of the Republic of Uzbekistan No. 8n-r / 555 of 30.02.2022).
This methodological recommendation made it possible to optimize the diagnosis and treatment tactics for various forms of nephritic syndrome in children;
The results obtained were implemented in the practice of health care, in particular, in the Republican Children's National Medical Center, in the 1st clinic of the Samarkand State Medical University, in the Samarkand Regional Children's Multidisciplinary Medical Center (conclusion No. 8 n-r/324 of 21.06.2022 of the Ministry of Health of Uzbekistan).
The application of the obtained results to practice has made it possible to reduce the frequency of recurrence of the disease in children, prevent complications of the disease, improve the quality of life of patients, diagnose and prevent the disease.
The structure and scope of the dissertation. The dissertation consists of an introduction, 4 chapters, conclusions, practical recommendations. The volume of the dissertation is 120 pages.
Бугунги давр ривожланган давлатлар қаторига қўшилиш, мамлакатимизда бозор ислоҳотларини чуқурлаштириш, жамиятни ижтимоий-иқтисодий ривожлантириш, аҳолини ижтимоий ҳимоялаш, ижтимоий хизматларнинг кенг тизимини яратиш, меҳнат бозорини ривожлантириш ва аҳоли турмуш д аражасини кўтариш имконини беру вчи ҳуқуқий асосларини мукаммаллаштириш зарурлиги билан изоҳланади. Утган қарийб 30 йиллик истиқлол даврида инсон, унинг ҳаёти, орзуси, дарду ташвишларини кун тартибига қўйишни ва бу борадаги ишлар кўлами самарадорлигини оширишни ҳаётнинг ўзи тақозо этмоқда. AMMO ҳал этилиши зарур бўлган муаммолар жамиятни асосий бўғинини ташкил этувчи оилаларнинг кундалик ташвишлари билан ҳам боғлиқ эканлигини замоннинг ўзи намоён этмоқда.
Ушбу мақолада кичик бизнеснинг инновацион фаолияти ҳудудлар иқтисодиётини ривожлантириш омили сифатида тадқиқот олиб борилган бўлиб, инновацион фаолияти бизнес жараёнларининг алоҳида тузилмаси, бошқарувнинг алоҳида объекти бўлиб, молиявий капитал,меҳнат ва бошқа ресурсларни бошқаришни ўз ичига қамраб олади. Тизимли ёндашувсиз бошқарув самарасиз бўлиб қолиши ва бу ҳолда инновациялар кичик бизнеснинг барча жараёнларига (интеллектуал, ижтимоий, иқтисодий, психологик) таъсир кўрсатиши лозим эканлиги таҳлил қилинган
The article examines the organization of regional tourist zones of our Republic, and also analyzes the potential of these zones to determine the directions of their development. Moreover, on the basis of an analysis of the possibilities of clusters in the improvement of regional tourist zones, the directions of development of this area are determined, and proposals and recommendations are given for the development of high-quality services for tourists.
The literature of recent years on the etiopathogenesis, clinical features and methods of treatment of dental diseases in children and adolescents with congenital cerebral palsy has been studied. The analysis of statistical data showed that the incidence of congenital cerebral palsy among children is increasing, the assistance provided to them with dental diseases is not effective enough. In patients, there is an increase in various pathological conditions of the oral cavity and teeth.
This article deals with a number of scientific proposals and practical recommendations for developing the company's priorities, identifying its strengths and weaknesses, opportunities and threats to its activities by assessing the current state of Uzbektelecom JSC in the context of the transition to innovative development of the national economy.