As a result of numerous clinical and experimental studies, a relationship has been established between changes in the oral cavity and pathology of internal organs. In modem dentistry, interest in research on concomitant pathologies is explained by the accumulation of new arguments, the emergence of new information in the system of the whole organism [3,5]. This analysis focuses on the prevalence of hepatitis infection and its various oral manifestations,consequences and clinical course. In this regard, the monitoring of outpatient records of patients with concomitant pathology, such as hepatitis А, В, C with inflammatory processes of the oral cavity and maxillofacial area after tooth extraction for emergency indications in the clinic of surgical dentistry of the clinic of the Tashkent State Dental Institute over the past 5 years was carried out.
The aim of the research work is determination of the prospects for the use of a domestic agent for the prevention of adhesion formation in thoraco-abdominal surgery on the basis of experimental and morphological studies.
Research objectives were white outbred rats in the amount of 62 individuals, in two experimental studies on the abdominal and pleural cavities, in each series of experiments the studies were carried out in 2 comparative groups, control and main. Experiments on the formation of adhesions in the abdominal and pleural cavities were carried out on the basis of the Republican Specialized Scientific and Practical Medical Center of Surgery named after acad. V.Vakhidov in the Department of Experimental Surgery for the period from 2019 to 2020.
The scientific novelty of the research consists of the followings: it is proved according to the data of experimental research that when modeling the adhesion process in the abdominal cavity, the local application of an anti-adhesion coating made of cellulose derivatives reduces the processes of adhesiogenesis and the development of changes in architectonics, bends and narrowings of the intestinal lumen; it was found in an experimental study that when modeling the adhesion process in the chest cavity, the local use of an anti-adhesion implant provides a significant decrease in the risk of adhesiogenesis in the form of the formation of coarse adhesions or planar adhesions; it was determined that when blood serum was applied over a powder implant, the quality of adhesion and the uniformity of its distribution on the surface of the experimental defect of the peritoneum or lung did not change, but, in contrast to activation by blood (to ensure a hemostatic effect), it was not accompanied by the development of cellular inflammation due to the resorption of thrombotic masses; it was found that the formation of a gel film over the area of damage to the peritoneum in the absence of cellular elements of blood makes it possible to achieve biodegradation of the coating without a pronounced cellular-inflammatory reaction, providing cicatricial replacement of defects with a significant reduction in the risk of developing a massive adhesive process; the morphostructural features of the formation of the adhesive process when using an anti-adhesive coating, characterized by regression in the dynamics of the number of connective tissue cells of the inflammatory infiltrate with scarring of the defect zone without the development of adhesive conglomerates with the surrounding tissues, have been determined.
Introduction of the research results. According to the results of a scientific study on a comparative analysis of the use of a domestic agent for the prevention of adhesion formation in thoraco-abdominal surgery: methodological recommendations were developed: "New technologies for the prevention of adhesions in thoraco-abdominal surgery" (certificate of the Ministry of Health No. 08-09/10055 of August 12, 2021). The proposed recommendations for performing surgical interventions on the organs of the abdominal and thoracic cavities will allow for sparing local hemostasis, as well as prevent the formation of a coarse adhesive process in the abdominal cavity.
The obtained scientific results on a comparative analysis of the use of the domestic remedy for the prevention of adhesion formation in thoraco-abdominal surgery have been introduced into the practical activities of health care, including in the Republican Specialized Scientific and Practical Medical Center for Surgery named after V.I. Academician V. Vakhidov, surgical departments of the clinics of the Andijan and Samarkand State Medical Institutes (certificate of the Ministry of Health No. 08-09/10055 of August 12, 2021). Based on the proposed results of experimental studies, it was shown that the use of an anti-adhesive coating made of cellulose derivatives made it possible to reduce the risk of adhesion formation from 60% to 20%, bowel deformation without manifestations of obstruction from 33.3% to 13.3% and the possibility of acute adhesive intestinal obstruction from 6.7% to 0%.
Structure and scope of the dissertation. The dissertation consists of an introduction, four chapters, conclusions, practical recommendations and a list of cited literature. The volume of work is 113 pages.
The course of project drawing, at Tashkent Architectural and Construction Institute is aimed at the formation of the graphic culture of students, as well as the creative potential of the individual. A lot of effective work in this area, especially in the teaching design drawing is achieved through the use of modern graphic software. Among graphic programs, in particular in the field of architecture, ArchiCAD is the best in the opinion of professionals. This program illustrates most effectively students, three-dimensional drawings for understanding architectural projects. This is necessary for students to fully understand the specifics of their profession.
Blockchain technology is “cross-cutting”, that is, one that can be applied in many areas of the economy, management, including state, municipal and social spheres. The relevance of the analysis of the experience of implementing the blockchain technology is determined by the provisions and the need to form the basis for the prospective assessment of the consequences of the implementation of this technology, both nationally and internationally. In this article, we study the international experience of applying this technology in the supply chain of logistics processes and give the necessary recommenda tions.
A conditioned reflex (temporal connection) is an individual reaction acquired during life through learning (as opposed to an unconditioned (innate) reflex). It is produced under certain conditions: the coincidence in time of the unconditioned stimulus and the neutral stimulus (a classic example: the presentation of food with the simultaneous ignition of a light bulb), as a result of which a reaction (for example, salivation) appears after a while to the presentation of only a neutral stimulus.
Successfully teaching foreign monologue speaking in professionally specific contexts hinges on carefully selecting specialized vocabulary tailored to the professional focus of the training. The instructional module for foreign language monologic speaking, coupled with informative reading, constitutes a meticulously designed exercise. It entails grasping and executing a semantic strategy encompassing the identification, assessment, and incorporation of professionally pertinent information. This process involves consolidating the acquired information, structuring it into a monologue outline, and independently delivering a monologue based on this framework.
ХХI аср ахборот технологияларининг жадал ривожланиши билан ажралиб туради. Ахборот технологияларининг такомиллаштирилиши ҳаётнинг барча жабҳаларида ўзгаришларга олиб келади. Ўзбекистон Республикаси божхона тизимида ахборот технологиялари қўлланилиши истиқболлари хусусида иқтисодий таҳлил ўтказиш, башорат қилиш, алоқанинг ривожланишини лойиҳалаштириш, илмий-тадқиқот ва тажриба-конструкторлик ишлари режаларини асослаб бериш, янги техникаларни тайёрлаш ва жорий қилиш, ишлаб чиқаришни ривожлантириш ва такомиллаштириш бўйича чоратадбирларни амалга ошириш ва ҳоказоларда самарадорликни аниқлаш, тармоқ ва унинг таркибидаги кичик тармоқларни ривожлантиришнинг тезлашган суръатларини асослаб бериш, ривожланишнинг энг самарали йўналишларини танлаб олиш, ишлаб чиқариш структураси ва бошқарув тизимини такомиллаштиришнинг асоси бўлиб хизмат қилиши, тармоқда самарадорликнинг ўсиши ва умуман ишлаб чиқаришнинг ўсишини рағбатлантириши лозим
C индром дефицита внимания с гиперактивностью(СДВГ) в детском возрасте относится к одной из актуальнейших проблем современной нейропедиатрии, в связи с высокой распространенностью и недостаточной изученностью патогенетических механизмов. В последние годы активно изучается новый раздел неврологии – поведенческая неврология, изучающая связь проблем поведения и обучения с неврологической основой, в которой важнейшее место занимают нейромедиаторные и нейротрансмиттерные нарушения. Согласно Международной классификации (МКБ-10), поведенческие и эмоциональные расстройства, начинающиеся обычно в детском и подростковом возрасте включают синдром дефицита внимания с гиперактивностью (гиперкинетические расстройства) (f90).
Сахарный диабет (СД) является сложным заболеванием, I мшровождающимся нарушением углеводного, жирового и других видов обмена, в регуляции которых участвуют ферменты, гормоны, витамины. Поскольку все процессы обмена веществ по своей сущности являются ферментными |н акциями и связь микроэлементов с этими реакциями является Пдиболее важной, изучение микроэлементного состава у г больных СД является вполне правомерным[3,4,5,6]. С этой шоки зрения, сахарный диабет можно считать сложным •I акро элемент озон, в развитии и течении которого большую I poni. играют дисбалансы макро- и микроэлементов [1,2].
Teaching a foreign language for medical specialist means the formation and development of their habits and skills in listening, speaking, reading and writing. There is no opportunity to develop such skills effectively if we do not about ways and methods of teaching in accordance with nowdays demands, important skills and the ways of forming them, the influence of formerly acquired habits on the formation of new ones, and many other necessary factors that modern methods and technologies of language teaching can supply us with. When adopting the practical aims for a higher educational institutions course the following factors are usually taken into consideration: the economic and political conditions of society, the requirements of the state, the general goals of high school education, the nature of the subject and the conditions for instruction. In the foreign language teaching, as well as in teaching of medicine and other subject, general prin-ciples are applied and, in their turn, influence and enrich the experiebce. At different periods, depending on the aims of teaching and earning a foreign language, new methods sprang up.
Ҳозирда ахборот-коммуникатив жараён жадал суратларда тезлашиб, коммуникация воситалари такомиллашиб бормоқда. Ҳар бир алоқа воситасининг ахборот етказиб беришда ўз услуби ва имкониятлари мавжуд. Оммавий алоқа воситаси телевидение техника ёрдамида вербал ва визуал коммуникация унсурларидан фойдаланиб ахборотни кўп сонли аудиторияга узатади. Коммуникант (томошабин) ва коммуникатор (телевидение, яъни мазкур манба орқали маълумотларни узатиш истагида бўлган соҳа вакиллари) ўртасида коммуникатив алоқа ўрнатилади. Коммуникант ахборотни визуал ҳамда вербал коммуникация орқали қабул қилади. Г.Г.Почепцов коммуникацияга “вербал ахборотни новербалга ва аксинча новербални вербалга қайта кодлаштириш жараёни” [Почепцов, Г.Г. 2001: с.14.] деб таъриф берган. Телевидениенинг ижод аҳлиэса вербал ва новербал воситалар ила ахборотни визуаллаштирад и. В а уста мусаввир ўз асарида турли рангларни чаплаштириб ташламаганидек, адиб, кино ва телевидение аҳли ҳам сўзларни талабчанлик билан танлаши лозим. Телевидение қаламга олинадиган сўзни ҳам, талаффуз этиладиган сўзни ҳам инкор этмайди. Бу қудратли восита тасвир яратишга, тасвирни тўлдиришга, томошабин - тингловчи билан алоқа ўрнатишга, мавзунинг концепциясини очишга хизмат қилиши назарда тутилади.
Diabetic retinopathy (DR) is considered a microcirculatory disease of the retina. However, new data are emerging that suggest that retinal neurodegeneration is an early event in the pathogenesis of DR, which may precede the development of microcirculatory disorders that occur in DR, as well asparticipate in them. Therefore, studying the underlying mechanisms that lead to neurodegeneration will be essential for identifying new therapeutic targets in the early stages of DR. Elevated glutamate levels, oxidative stress, overexpression of the renin-angiotensin system, and activation of glycation end-product receptors play important roles in diabetic-induced retinal neurodegeneration. Finally, the balance between neurotoxic and neuroprotective factors is critical in determining the survival of retinal neurons. In this review, we focus on neurotrophic factors already synthesized by the retina under physiological conditions, and we also discuss current neuroprotective strategies and future directions for the treatment of DR