Соблюдение принципов антибактериальной терапии поможет врачам эффективно и безопасно применять антибактериальные препараты, снизить развитие резистентности микробов к антибактериальным препаратам.
Актуальность исследования: Фотодинамическая терапия (ФДТ) - один из новейших методов лечения воспалительных заболеваний, вызванных теми или иными инфекциями или хроническим воспалением, с успехом применяется в ряде европейских стран с 1999 года. Лечение заключается в обработке патогенных зон лазером с предварительным нанесением фотосенсибилизатора. После лазерного воздействия образуется фотокоагуляционная пленка, предохраняющая от повторного проникновения микробов.
В областном противотуберкулезном диспансере Хорезмской области г. Ургенча в детском отделении мы применили метод Арт терапии для лечения больных детей туберкулезом. В данной представленной статье рассматривается арт-терапия как одно из направлений современной психотерапии во взаимосвязи с возможностями ее применения в педиатрической практике. Подробно описаны виды арт-терапии — рисование, музыкотерапия. Также рассмотрены главные механизмы лечебного воздействия, особенности проведения сеансов в зависимости от формы музыкотерапии, рисования. Нами указаны основные сферы применения в педиатрической практике.
The article deals with the study effective and safe use NAID (non-steroidal and anti-inflammatory drugs at patients’ treatment). The rational use NAID will help to guarantee the safety of pharmacotherapy.
BACKGROUND: Sepsis is one of the leading causes of hospital mortality in children. a decisive role in improving the results of treatment of this group of patients belongs to early diagnosis and pathogenetic therapy. AIM: this study optimizes the diagnosis and intensive care of surgical sepsis in children based on clinical and laboratory criteria and bacteriological monitoring.
MATERIALS AND METHODS: the study period is 2018–2020. the study subjects were children (n = 73) with surgical pathology (diffuse purulent peritonitis, bacterial destruction of the lungs, post-traumatic brain hematomas, injuries of the abdominal organs, and others). clinical and laboratory parameters were analyzed, and microbiological monitoring was performed to determine antibiotic sensitivity.
RESULTS: Patients who developed sepsis had a pronounced hypermetabolic syndrome, which was manifested by tachycardia and tachypnea, hyperthermia, low levels of albumin, and total protein in the blood. Protein catabolism in patients was accompanied by a decrease in globulins (IgG) synthesis and the development of a secondary immunodeficiency state. Both gram-positive and gram-negative microorganisms were involved in developing surgical sepsis in children, increasing the proportion of the latter. Given the high proportion of multi-resistant flora, empirical combined de-escalation antibiotic therapy (aBt) with broad-spectrum antibiotics was prescribed. this was followed by its revision based on microbiological monitoring and clinical and laboratory data of the patient with sepsis. Studies have shown the effectiveness of complex intensive care in 86.3% of cases. Mortality occurred in 13.7% of cases. Patients with severe surgical pathology died: fecal, generalized peritonitis, severe traumatic brain injury + coma with irreversible neurological disorders, and urosepsis against the background of chronic renal failure after repeated surgical interventions.
CONCLUSIONS: early diagnosis of sepsis, rational aBt under the control of microbiological monitoring, non-aggressive infusion therapy, and active sanitation of the surgical infection focus contributed to a decrease in mortality in this category of patients.
Abstract. In ischemic heart disease (CHD), progressive disorders of the hemostasis system are corrected with shorter and longer antiplatelet therapy. However, recent studies have consistently demonstrated the development of up to 25% of all possible side effects and complications of anticoagulant and antiplatelet therapy.
Purpose of the study: to study the effect and complication of anticoagulant therapy on the state of the gastroduodenal zone in patients with ischemic heart disease.
Material and methods: 146 patients with ischemic heart disease (CHD), were examined, among them there were 12 (8.22%) patients with acute myocardial infarction (MI), 68 (46.57%) with progressive intense angina pectoris (PNS), intense angina pectoris (NS , functional class III-IV) - 66 (45.20%) people. The average age of the patients was 56.3 ± 2.4 years.
Results and its discussion: in the present study, the “ulcerative” history was assessed and whether there was a complication (bleeding, penetration or perforation). Detailing the data of the anamnesis made it possible to establish that the "ulcerative" anamnesis was detected only in 22.60% of cases. In other cases, as the duration of the course of the disease increases and, accordingly, the duration of the use of antiplatelet agents and anticoagulants, there is a directly proportional relationship to the increase in the frequency of gastropathy.
The author shows the clinical and statistical study of the impact of various risk factors (age, sex, bad habits, dietary treatment, occupational hazard) for the development of pathology gepatopankreatoduodenalnoy system, the gravity of the current.