Hereditary coagulopathies characterized by reduced blood clotting occupy a special place among diseases of the blood system. The most common of these are hemophilia and Willebrand's disease. Hemophilia-the disease of "royals" - is an old, but still relevant disease.
Hereditary coagulopathies, characterized by reduced blood clotting, occupy a special place among diseases of the blood system. Based on who data and the likely frequency of research on these diseases, the prevalence of hemophilia ranges from 3 to 25 patients per 10,000 population.
Few studies of the oral cavity in patients with hemophilia have shown a high level of dental diseases, poor hygiene of the oral cavity. This is due to the lack of proper oral care, and dispensary monitoring, fear of prolonged bleeding after dental manipulations. For this reason, dentists try to avoid treating dental diseases in this category of patients.
At the same time, modern achievements of medical science in the field of Hematology and the development of effective replacement therapy allow to prevent almost all types of bleeding.
However, this group of patients is still unable to receive timely and high-quality dental treatment and prevention, which largely determines the high prevalence of inflammatory diseases of the maxillofacial region.
All of the above is evidence of the presence of many predisposing factors of damage to the dental system in patients with hemophilia, as well as the need for preventive, therapeutic, including orthopedic dental measures for this category of patients.
The article is devoted to some features of the trade relations of the Kokand Khanate with neighboring countries, particularly with the emirate of Bukhara and the khanate of Khiva. Analysis of merchants’ conditions, demand for goods from Russia, China and Iran in domestic market and information about selling goods is been given in it.
Таким образом, боль после лечения корневых каналов обычно колеблется от легкой до умеренной и может возникать даже после оптимально проведенного лечения корневых каналов. Недавние достижения в эндодонтии позволили снизить частоту возникновения боли после лечения корневых каналов и повысить удовлетворенность пациентов в отношении послеоперационной боли.