Subject of the inquiry: 298 patients with finn deformations of the larynx and trachea
Aim of the inquiry: early rehabilitation of patients with firm deformations of the larynx and trachea path optimization and creating clinical and pathogenic methods of complex treatment.
Methods of the inquiry: clinical examination, special examination: LOR-examination, endoscopy of air ways, X-ray, CT, MRI of larynx, trachea and bronchus, bacterial examination of larynx and trachea wounds; morphological examination, biochemical methods of examination: lipid peroxidation, antioxidant enzymes, activity of hepatic monooxygenase system (MOS); biophysical methods of examination: исследование electric damage of erythrocytes’ membrane (EDEM), blood viscosity (BV) and blood shift velocity (BSV); cytological examination.
The results achieved and their novelty: In patients with firm deformations of the larynx and trachea, firstly basing on complex investigation clinical and structural-functional parameters revealed pathomorphological changes in neck tissues as chronic inflammation with productive component. Despite, revealed disrupt balance of process lipid peroxidation and antioxidant system, hydroxylic function of liver, decrease of electoral penetrability of erythrocytes’ membrane and aggravate of hemorheology. With this, level of expression of changes depends on clinic form and load disease, correlate with stage of wound healing and after restore of functions of the larynx and trachea gradually becoming normal. Presented classification of the firm deformations of the larynx and trachea, permitting complexly counting etiologic factor and morphological variant of the damage of laryngotracheal tract. In scheme of the pathogenic complex conservative therapy before and after reconstructive operations included medicine, influencing on Hemodynamic, with ability membranotrope action, systemic enzymotherapy, immunostimulators, and correction of the tissue metabolism by laser. Created private and modified methods of reconstructive laryngotracheoplasty in case of cicatricle stenosis of glottic and subglottic parts, bilateral paralyses of the larynx, cicatricle deformations of pharyngolarynx, combination deformations and defects of the larynx and trachea, permitting single stage restore laryngotracheal ways.
Practical value: The investigation of pathogenic mechanism of developing of the firm deformations of the larynx and trachea on data of changes of main functional and metabolic processes will permit not only activating and improving of pathogenic therapy, and forecasting variant of development and course of postoperative period after reconstructive operations.
Use of proposed methods of complex conservative and surgical treatment of the firm deformations of the larynx and trachea allowed to provide whole volume of restoring means in more short time and with less quantity of stage operations, preoperative preparing till 3 days, hospital stay till 14-20 days, surgical operations in 1.9 time.
Degree of embed and economical effectivity: The results of investigation intruded in treatment practice of the First and Second Tashkent Medical Institutes, LOR-clinics of Samarqand territorial children hospital, territorial hospital of Karshi. Materials of the investigation using in study process of LOR - cathedra First Tashkent Medical Institutes during lectures and practice tutorials with students, magistracies, and clinic ordinators. Determined main economic effect in use of proposed complex therapy in connection with reduce of term of treatment and hospital stay (on an average 10 days) and taking off or decreased disability on 67% patients.
Sphere of usage: otorhinolaryngology, surgery, reanimation
The aim of the study was to assess the effectiveness of the use functional food products aimed at reducing the content of table salt in the body. According to the research results, a positive trend towards an increase in the level of sodium excretion in urine was revealed in students who received functional food products made from local products rich in potassium and low in sodium, developed by us in the standard "Products of functional nutrition NUMA".
Изучить предикторы формирования факторов риска у больных параноидной шизофрении,перенесших нарушение мозгового кровообращения.
Mazkur maqolada о‘z-о‘zini rivojlantirishning o‘ziga xos xususiyatlari tahlil etilgan. Shuningdek, maqolada о‘z-о‘zini anglash imkonini beruvchi topshiriqlar, о‘z о‘rnini belgilab olishga imkoniyat beruvchi topshiriqlar, о‘quvchilarni hamkorlikda rivojlanishiga qaratilgan topshiriqlar, о‘zini о‘zgartirish, rivojlanishga qaratilgan topshiriqlar ham berilgan.
При гипопаратиреозе отсутствие или недостаточность ПТГ неизбежно сопровождается развитием гипокальциемии. К основным патогенетическим механизмам относятся: снижение активности остеокластов с уменьшением высвобождения кальция из костей; повышение экскреции кальция с мочой; подавление синтеза кальцитриола в почках и снижение абсорбции кальция из кишечника.
This article analyzes the foreign experience of improving agriculture. It also shows the ways to implement and effectively use innovative technologies in this area
This article analyzes the works of the Chinese writer Lao She “Catcountry”. The author examines the factors that cause the degradation of Chinese culture and its figurative interpretation through a work of art.The novel satirically describes the current events in the city of cats. Lao She shows the negative circumstances in Chinese culture, spirituality, and enlightenment. The article says that the novel is also significant from a modern point of view.
Актуальность приобретает проблема психоэмоциональных реакций мужчин с бесплодием, что обусловлено недостаточной изученностью влияния психического здоровья на репродуктивную систему человека, что значительно повышает относительный риск развития бесплодия. При стрессовых воздействиях организм отвечает системно, при этом взаимодействуют иммунная, нервная и эндокринная системы. Изменение уровня эндокринной регуляции при стрессе оказывает непосредственное влияние на иммунный ответ. Различные формы иммунного ответа могут возникать как в центральной, так и в периферической нервной системе.
In the works of prominent representatives of modern Arabic and Uzbek literature, Gad al-Samman and Zulfiya Kurolboy kizi, the psychological image and style, which is very relevant in the field of literature today, is in the center of attention of a wide range of readers and literary critics. The prose of these two writers, in particular, is characterized by the fact that their stories are created in the environment and reality of different socio-political situations. This article discusses the issues of psychologism and
psychological analysis in the stories of Gada as Samman and Zulfiya Kurolboy kyzy, as well as the common features of the works of the two writers. The similarity of the style of writers is revealed, as well as the possibility of using tools of psychological analysis, such as internal monologue, speech characteristics, psychological portrait, hallucinations, dreams, reveals the inner world of the protagonist. The writers Gada as Samman and Zulfiya Kurolboy kizi also include psychological analysis in their work, such as inner speech - inner replica, inner dialogue, inner monologue (monologue-discussion, monologue-memory, monologue-reflection), speech characteristics, portrait, repetition, hallucinations, skillfully using their tools, create prose works enriched with elements of psychological and magical realism. In particular, the depiction of psychological images, inner speech, and the concept of inner monologue play an important role in their work. Similar ideas in the works of two writers who lived and worked in different countries, having no connection and influence, the harmony of the author's intention, commonality in society, the harmony of the author's style Gada al-Samman and the daughter of Zulfiya Kurolba, a certain shift in literary processes proves that he was one of the creators who influenced the rise.
Obstetric hemorrhages, despite the global measures introduced to prevent them, still represent a real threat to the maternal health and life, and require a search for more effective measures for their prevention and treatment. The list of references which formed the basis for the present review will allow the reader to determine the vector of searching for modern information on obstetric hemorrhages, to compare the outcomes of labor with postpartum hemorrhage in different countries, and to understand the prognostically significant risk factors.
Явилось изучение эффективности вакцинопрофилактики гепатита В у детей с острым лимфобластным лейкозом и её протективный уровень.
Today, in our Republic, most of the baking oils are margarines prepared on the basis of food salami. These margarines do not meet the standards of trans acid content (more than 2%). The research paper presents the results of hydrogenation of cotton palmitin in the presence of a regenerated catalyst, the melting temperature of which is less than 59 °C and the iodine number of no more than 6, and the preparation of a recipe for margarine with reduced trans acid content, which is used in baking based on it.
Изучение современного состояния транспортно-логистической системы. Характеристика системных проблем и рисков. Особенности зарубежного опыта функционирования транспортно-логистических систем, применение выборочного контроля на основе управления рисками.