The microbial factor is essential in the etiology of mastitis. In this regard, bacteriological diagnostics is one of the decisive moments in the recognition and differentiation of pathological conditions of the mammary gland.
However, it takes a lot of time to make a diagnosis using general methods, special culture media and reagents.
Получить достоверные данные регистра инсульта в Кашкадарьинской области.
This study is based on the comparison between management versus PCI in patients with CAD. The prevalence of the major forms of cardiovascular disease (CVDs), mostly coronary artery disease (CAD), has changed dramatically in recent years. Cardiovascular disorders are now the one of the major cause of death and disability in the world.1 In 2015, 17.7 million individuals died from cardiovascular disease (CVD), which is around 31% of all deaths worldwide; 7.4 million pass away from coronary artery disease (CAD), and 6.7 million expired from stroke. 2 CAD is also the major cause of death, count for 13.2% of all deaths globally.3 It is responsible for one-quarter of all deaths in the United States of America (USA). About 75 percent of people with CAD in European countries are between the ages of 27 and 34.4 CAD was accountable for 16% of all man deaths and 10% of all female deaths in the England.5 Sudden death and CAD have a close connection. According to post-mortem reports and death certificates, 62-85 percent of patients who expired outside of the clinic have a past of CAD.6 As per informations from the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2014, myocardial infraction affects 3.0% of the mature people in the USA (3.3 percent of males and 2.3 percent of females). An MI occurs every 40 seconds or so in the USA. In the USA, the mean age at 1st MI is 65.6 years for guys and 72.0 years for ladies.7 In this study the management and PCI are compared in patients with CVD.
Инсульт является чрезвычайно распространенным заболеванием. В Узбекистане заболеваемость мозговым инсультом колеблется от 0,9 до 1,4 на 1000 населения, а в г.Ташкенте 1,5 на 1000 населения. В последние годы происходит увеличение числа лиц, перенесших инсульт, одновременно с этим снижается летальность при этом заболевании. В настоящее время подходы к восстановлению больных после инсульта многообразны и включают восстановление как двигательных расстройств, так и высших психических функций.
Изучить особенности мнестического дефекта у больных с полушарным ишемическим инсультом и пути его коррекции в неотложной неврологии.
Инсульты одна из важнейших проблем общества, являются основной причиной длительной инвалидизации больных. Ежегодно в мире регистрируются более 15 млн инсультов.
Одним из наиболее частых диагнозов в амбулаторной и стационарной практике является «вертебрально-базилярная недостаточность» — ВБН (син.: «недостаточность кровообращения в вертебрально-базилярной системе-ВБС»,«дисциркуляция в ВБС»)
Purpose of the study: to study the effect of the combination of valsartan and sacubitril on the indices of central hemodynamics in patients with coronary heart disease (CHD) within 2 years after revascularization. Material and research methods. The study included 320 patients with coronary artery disease who underwent coronary revascularization. All patients were divided into 2 groups: patients who received valsartan (group B, 160 people), patients who received ARNI - a combination of valsartan and sacubitrile molecules (group C, 160 people). At baseline and in dynamics after three months, at the end of the first and second years of follow-up after revascularization in patients with coronary artery disease systolic the blood pressure (SBP, mm Hg), diastolic blood pressure (DBP, mm Hg), heart rate in minute, the concentration of brain natriuretic peptide (BNP) in the blood were determined. Also, during echocardiography, the stroke volume of the heart, indexed to the body surface area (SI, ml / m2), the minute index (MI, ml / m2), the mean pressure in the pulmonary artery (PA, mm Hg) were determined. Research results. In the group of patients taking valsartan (group B), the relative dynamics of BNP concentration was -10.69 ± 0.55% by the 3rd month of observation, -21.24 ± 1.03% by the end of the 1st year, and -34, 39 ± 1.64% by the end of the 2nd year of observation. The inclusion of sacubitril in the therapy scheme contributed to a greater positive effect in reducing the BNP concentration: the relative dynamics of the BNP concentration was -10.30 ± 0.52% by the 3rd month of observation, - 21.91 ± 1.00% by the end of the first year of observation, and -39.28 ± 1.67% (p <0.05 significant difference with group B). By the end of the 1st and 2nd years of observation, the use of a combination of valsartan and sacubitril contributed to a more pronounced decrease in blood pressure (p <0.01), a more pronounced dynamics of MI (p <0.05) and a decrease in pressure in РA (significantly lower baseline indicators, p <0.05 and indicator in group B, p <0.01). Conclusion. The present study revealed a positive effect of revascularization and subsequent therapy of coronary artery disease with the inclusion of sacubitrile on the BNP concentration, blood pressure and mean pressure of pulmonary artery.
Оценка двигательных, когнитивных расстройств у пациентов с ХСМН и оценка их динамики после проведения курса реабилитации.
Изучить уровень информированности населения города Ташкента о факторах риска, способы профилактики ОНМК.
С осудистые заболевания головного мозга представляют собой актуальную медико-социальную проблему,занимающую ведущее место в структуре заболеваемости и смертности в экономически развитых странах [1,18]. В последние годы структура заболеваний нервной системы меняется за счет нарастания ишемических форм. Это обусловлено повышением удельного веса артериальной гипертензии и атеросклероза как основной причины сосудистой патологии мозга [49,25]. Атеросклеротическое поражение сосудов, питающих головной мозг встречается у мужчин в 4 раза чаще,чем у женщин. Возраст большинства больных превышает 50 лет, но нередко это заболевание выявляется у лиц в возрасте 30-49 лет [48,20].
Анализ научной литературы последних лет демонстрирует неуклонный рост сосудистых заболеваний нервной системы, количество которых не только не уменьшилосьно и значительно увеличилось и изменилось в плане охвата населения различного возраста. В настоящее время инсульт развивается не только у лиц преклонного возраста, но и молодых людей, а в отдельных случаях даже у детей [20].
Nowadays, dependence on many types of clinical manifestations of APS has become an interdisciplinary problem that is widely studied by various medical specialties around the world: neurologist, rheumatologist, obstetriciangynecologist, dermatologist, and others. L.A. to study APS in Russia. Kalashnikov (neurologist), E.A. Nasonov (rheumatologist), T.M. Reshetnik (rheumatologist), Z.S. Barkagan (hematologist) and others made significant contributions. The first publication on the study of APS was published in 1990 in Ukraine by gynecologist Professor T.N. Demina and neurologist Professor S.K. Belonging to Evtushenko and his students [1; 143-146-p., 3, 4; 39-41-b 84-86-b.]. The results of many years of research on the neurological aspects (aspects) of AFS based on Donetsk National Medical University were presented by Professor S.K. The role of antiphospholipid antibodies in the development of cerebrovascular pathology in young people under the guidance of Evtushenko (M.F. Ivanova), "Cerebral palsy in children born to mothers with seropositive and seronegative variants of antiphospholipid syndrome" (M.A. Moskalenko in 2003). completed. In 2004, Professor S.K. Evtushenko visited Professor G. Hughes Clinic in London and got acquainted with the Lupus Journal Foundation, which publishes laboratory work, systemic connective tissue diseases, and scientific work related to APS. In recent years, the number of publications made by Ukrainian authors has increased. According to foreign and Russian authors, the incidence of APS hypercoagulability in the general population is 5% among young people [19; 513-518-b., 20; Pp. 1217, 39; Pp. 9-20]. The disease is observed in children even in newborns [17, 26; Pp. 21-25, 39; Pp. 9-20]. In the general population, APS is more often detected in women than in men (1: 5 ratio), probably due to women's predisposition to systemic connective tissue disease [6; 9-b.]. In 11.8% of cases, stroke was associated with APS among young women [20; Pp. 12-17].
Изучить состояния церебральной гемодинамики у больных с атеросклерозом головного мозга в остром периоде ишемического инсульта и определение методов вторичной профилактики ишемического инсульта.